22355-1-AP

antibody from Proteintech Group

Targeting: CXCL9 CMK, crg-10, Humig, MIG, SCYB9

Provider product page for 22355-1-AP

ELISA

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [30]
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Product number: 22355-1-AP - Provider product page
Provider: Proteintech Group
Product name: MIG antibody
Antibody type: Polyclonal
Description: MIG antibody (Cat. #22355-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC,ELISA.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

CXCL9 protein structure - 22355-1-AP shown in red.

Submitted references Inhibiting ADAR1-Mediated Excessive Epigenetic A-to-I RNA Editing Improves the Immune Microenvironment and Increases Sensitivity to Immunotherapy in Lung Adenocarcinoma.

Wang S, Zheng S, Liu C, Zhang C, Wang X, Wang Z, Wang Y, Feng X, Xue Q, Sun N, He J
MedComm 2026 Mar;7(3):e70574

CHB-Induced Immune Zonation Chaos Elicited LXRα-mediated Lipid Metabolism Disorders in Kupffer Cells to Induce Cancer Stem Cell Formation.

Shi J, Li Q, Li J, Bai J, Xi J, He Q, Zhou J, Wang X, Song X, Li X, Yue X, Zhang X, Sun Z, Li J, Yang W, Cui Y, Shu W, Guo L, Wang S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(10):e10275

CXCL9 as a key feature for deep learning-based immune subtyping and prediction of immune checkpoint blockade response in triple-negative breast cancer.

Li J, Xu B, Shi Q, Deng Y, Li Y, Jin W, Zhu Y, Jiang R, Qu S, Teng L, Wu C
International immunopharmacology 2026 Apr 15;175:116439

Reciprocal activation between M1 macrophages and trophoblasts through CXCL9/STAT1/ZEB1/CCL2 axis promotes recurrent spontaneous abortion.

Yan S, Wang X, Wu Q, Ding J, Qiu H
Frontiers in immunology 2025;16:1629370

Baicalin promotes anti-tumor immunity in hepatocellular carcinoma through HIF-1α/Lactate/CXCL9 axis.

Yang X, Chen W, Sun H, He C, Liu Y, Qin M, Jiang W, Wang Y, He S
Biochemical pharmacology 2025 Nov;241:117157

Radiogenomic analysis of clinical and ultrasonic characteristics in correlation to immune-related genes in breast cancer.

Dou T, Chen Y, Liu L, Zhang Y, Pei W, Li J, Lei Y, Wang Y, Jia H
Scientific reports 2025 May 7;15(1):15918

Unravelling the transcriptome of the human tuberculosis lesion and its clinical implications.

Fonseca KL, Lozano JJ, Despuig A, Habgood-Coote D, Sidorova J, Aznar D, Arias L, Del Río-Álvarez Á, Carrillo-Reixach J, Goff A, Wildner LM, Gogishvili S, Nikolaishvili K, Shubladze N, Avaliani Z, Tapia G, Rodríguez-Martínez P, Cardona PJ, Martinón-Torres F, Salas A, Gómez-Carballa A, Armengol C, Waddell SJ, Kaforou M, O'Garra A, Vashakidze S, Vilaplana C
Nature communications 2025 May 30;16(1):5028

Melatonin Alleviates Behavioral and Neurodevelopmental Abnormalities in Offspring Caused by Prenatal Stress.

Wu D, Du J, Zhao T, Li N, Qiao X, Peng F, Wang D, Shi J, Zhang S, Diao C, Wang L, Zhou W, Hao A
CNS neuroscience & therapeutics 2025 Mar;31(3):e70347

Ultra-high dose rate radiotherapy overcomes radioresistance in head and neck squamous cell carcinoma.

Li HS, Tang R, Shi HS, Qin ZJ, Zhang XY, Sun YF, Wei ZG, Ma CF, Yang L, Chen Y, Liu ZR, Zhu LL, Yang W, Yang L, Xu AN, Zhang Z, Liao SQ, Shi JS, Deng JJ, He XZ, Peng XC
Signal transduction and targeted therapy 2025 Mar 3;10(1):82

Spatial transcriptomics reveals tryptophan metabolism restricting maturation of intratumoral tertiary lymphoid structures.

Tang Z, Bai Y, Fang Q, Yuan Y, Zeng Q, Chen S, Xu T, Chen J, Tan L, Wang C, Li Q, Lin J, Yang Z, Wu X, Shi G, Wang J, Yin C, Guo J, Liu S, Peng S, Kuang M
Cancer cell 2025 Jun 9;43(6):1025-1044.e14

Rubia cordifolia L. extract ameliorates vitiligo by inhibiting the CXCL10/CXCL9/STAT1 signaling pathway.

Xia M, Li Z, Yang C, Wang Y, Zhang J, Zhong G, Ouyang H, Feng Y
Journal of ethnopharmacology 2025 Jun 26;350:120027

RANKL/PD-1 dual blockade demonstrates survival benefit for patients with advanced lung adenocarcinoma harboring KRAS mutations.

Li HS, Liu CM, Zheng SF, Wu P, Xu HY, Hao XZ, Li JL, Xing PY, Duan JC, Wang ZJ, Zhong J, Tian LY, Cui YY, Fang Q, Lei SY, Wang SH, Luo YJ, Wang ZY, Wang J, He J, Sun N, Wang Y
Cell reports. Medicine 2025 Jul 15;6(7):102235

Histone deacetylases 10 as a prognostic biomarker correlates with tumor microenvironment and therapy response in colorectal cancer.

Nie HH, Yang XY, Zhou JK, Gao GL, Ding L, Hong YT, Yu YL, Qiu PS, Zeng ZY, Lai J, Zheng T, Wang HZ, Zhao Q, Wang F
World journal of gastroenterology 2025 Jul 14;31(26):108662

Neutrophil membrane-coated circular RNA nanoparticles for targeted immunotherapy in HER2-positive breast cancer brain metastasis.

Liu Y, He W, Li X, Lu X, Wu C, Gao Y, Fan D, Dong C, Zhao H
Cell communication and signaling : CCS 2025 Jul 10;23(1):333

TMT-based quantitative proteomics unveils the protective mechanism of Polygonatum sibiricum polysaccharides on septic acute liver injury.

Xiao L, Ping Y, Sun S, Xu R, Zhou X, Wu H, Qi L
Journal of proteomics 2025 Jan 6;310:105331

Glucose starvation mimetic aldometanib removes immune barriers permitting mice with hepatocellular carcinoma to live to normal ages.

Hu HH, Wang X, Lan B, Cheng H, Wen H, Chen F, Wu J, Li M, Chen J, Zhang J, Chen D, Lin S, Lin J, Yang M, Wu Z, Zheng ZZ, Chen F, Zhou J, Chen G, Chen Y, Deng X, Zhang CS, Liu J, Lin SC
Cell research 2025 Dec;35(12):934-953

CCL8 suppresses ovarian cancer progression via M1 macrophage polarization and NF-κB-mediated apoptosis.

Fang J, Zhao X, Wang J, Yang Y, Xiao Y
Scientific reports 2025 Dec 17;16(1):2960

Microwave ablation combined with α-PD-L1 enhances abscopal effect and promotes CTL activation and intratumoral homing by a cytokine network involving IFN-γ and CXCL9.

Ma F, Miao X, Lin Y, Luo X, Chen T, Ni Z, Wang X
International immunopharmacology 2025 Apr 24;153:114498

Development and clinical validation of a seven-gene signature based on tumor stem cell-related genes to predict ovarian cancer prognosis.

Wang G, Liu X, You Y, Chen S, Chang X, Yang Q
Journal of ovarian research 2024 Mar 13;17(1):58

Single-cell transcriptome dissecting the microenvironment remodeled by PD1 blockade combined with photodynamic therapy in a mouse model of oral carcinogenesis.

Dong Y, Zeng K, Ai R, Zhang C, Mao F, Dan H, Zeng X, Ji N, Li J, Jin X, Chen Q, Zhou Y, Li T
MedComm 2024 Jul;5(7):e636

Blockade of C5a receptor unleashes tumor-associated macrophage antitumor response and enhances CXCL9-dependent CD8(+) T cell activity.

Luan X, Lei T, Fang J, Liu X, Fu H, Li Y, Chu W, Jiang P, Tong C, Qi H, Fu Y
Molecular therapy : the journal of the American Society of Gene Therapy 2024 Feb 7;32(2):469-489

Spatial patterns and MRI-based radiomic prediction of high peritumoral tertiary lymphoid structure density in hepatocellular carcinoma: a multicenter study.

Long S, Li M, Chen J, Zhong L, Abudulimu A, Zhou L, Liu W, Pan D, Dai G, Fu K, Chen X, Pei Y, Li W
Journal for immunotherapy of cancer 2024 Dec 15;12(12)

Defining cell type-specific immune responses in a mouse model of allergic contact dermatitis by single-cell transcriptomics.

Liu Y, Yin M, Mao X, Wu S, Wei S, Heng S, Yang Y, Huang J, Guo Z, Li C, Ji C, Hu L, Liu W, Zhang LJ
eLife 2024 Aug 30;13

CD276-dependent efferocytosis by tumor-associated macrophages promotes immune evasion in bladder cancer.

Cheng M, Chen S, Li K, Wang G, Xiong G, Ling R, Zhang C, Zhang Z, Han H, Chen Z, Wang X, Liang Y, Tian G, Zhou R, Zhu Y, Ma J, Liu J, Lin S, Xu H, Chen D, Li Y, Peng L
Nature communications 2024 Apr 1;15(1):2818

LRPPRC facilitates tumor progression and immune evasion through upregulation of m(6)A modification of PD-L1 mRNA in hepatocellular carcinoma.

Wang H, Tang A, Cui Y, Gong H, Li H
Frontiers in immunology 2023;14:1144774

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Xi Z, Yang T, Huang T, Zhou J, Yang P
Biomedicines 2023 Nov 24;11(12)

CXCL9 influences the tumor immune microenvironment by stimulating JAK/STAT pathway in triple-negative breast cancer.

Wu L, Sun S, Qu F, Sun M, Liu X, Sun Q, Cheng L, Zheng Y, Su G
Cancer immunology, immunotherapy : CII 2023 Jun;72(6):1479-1492

Activation of the chemokine receptor 3 pathway leads to a better response to immune checkpoint inhibitors in patients with metastatic urothelial carcinoma.

Feng W, Lin A, Sun L, Wei T, Ying H, Zhang J, Luo P, Zhu W
Cancer cell international 2022 May 13;22(1):186

A comparison expression analysis of CXCR4, CXCL9 and Caspase-9 in dermal vascular endothelial cells between keloids and normal skin on chemotaxis and apoptosis.

Dong X, Zhang M, Chen Y, Li C, Wang Y, Jin X
Journal of plastic surgery and hand surgery 2022 Apr;56(2):93-102

Avoiding Absolute Quantification Trap: A Novel Predictive Signature of Clinical Benefit to Anti-PD-1 Immunotherapy in Non-Small Cell Lung Cancer.

Liu C, Wang S, Zheng S, Xu F, Cao Z, Feng X, Wang Y, Xue Q, Sun N, He J
Frontiers in immunology 2021;12:782106

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