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ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
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- Product number
- RA0694 - Provider product page
- Provider
- Oursmab
- Product name
- Sirtratumab (Biosimilar Reference Antibody) (SLITRK6)
- Antibody type
- Monoclonal
- Description
- Sirtratumab is a humanized IgG2 monoclonal antibody targeting SLIT and NTRK-like family member 6 (Slitrk6), a transmembrane protein involved in neural development and cell adhesion. It binds to Slitrk6, which is overexpressed in certain tumors (e.g., neuroendocrine and some solid tumors), aiming to inhibit tumor progression through modulation of signaling pathways or induction of antibody-dependent cellular cytotoxicity (ADCC). It is being developed for the treatment of Slitrk6-positive cancers.
- Reactivity
- Human
- Isotype
- IgG
- Vial size
- 100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg
- Concentration
- Bottled at the concentration indicated on the vial.
- Storage
- Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.
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Supportive validation
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- Oursmab (provider)
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- Experimental details
- Sirtratumab (Biosimilar Reference Antibody) (SLITRK6)-RA0694-Oursmab determined by SDS-PAGE. The purity of the protein is greater than 98%.
