Antibody data
- Antibody Data
- Antigen structure
- References [17]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 10763-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10763-1-AP, RRID:AB_2115506
- Product name
- GSPT1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated GSPT1 antibody (Cat. #10763-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Discovery of novel BTK PROTACs with improved metabolic stability via linker rigidification strategy.
GSPT1 Functions as a Tumor Promoter in Human Liver Cancer.
Degradation of neurodegenerative disease-associated TDP-43 aggregates and oligomers via a proteolysis-targeting chimera.
Discovery of a potent BTK and IKZF1/3 triple degrader through reversible covalent BTK PROTAC development.
An integrative analysis of the lncRNA-miRNA-mRNA competitive endogenous RNA network reveals potential mechanisms in the murine hair follicle cycle.
Overexpression of eRF3a Promotes Cell Proliferation and Migration in Liver Cancer.
Hsp90 is involved in pseudorabies virus virion assembly via stabilizing major capsid protein VP5.
Long non-coding RNA LINC00511 promotes proliferation, invasion, and migration of non-small cell lung cancer cells by targeting miR-625-5p/GSPT1.
A Cereblon Modulator CC-885 Induces CRBN- and p97-Dependent PLK1 Degradation and Synergizes with Volasertib to Suppress Lung Cancer.
Spatiotemporal Proteomic Analysis of Stress Granule Disassembly Using APEX Reveals Regulation by SUMOylation and Links to ALS Pathogenesis.
Downregulation of microRNA-27b-3p via aberrant DNA methylation contributes to malignant behavior of gastric cancer cells by targeting GSPT1.
A Novel Rac1-GSPT1 Signaling Pathway Controls Astrogliosis Following Central Nervous System Injury.
A novel cereblon modulator recruits GSPT1 to the CRL4(CRBN) ubiquitin ligase.
Polyamine stimulation of eEF1A synthesis based on the unusual position of a complementary sequence to 18S rRNA in eEF1A mRNA.
Nicotine-mediated invasion and migration of non-small cell lung carcinoma cells by modulating STMN3 and GSPT1 genes in an ID1-dependent manner.
Mammalian hyperplastic discs homolog EDD regulates miRNA-mediated gene silencing.
Readthrough of nonsense mutation W822X in the SCN5A gene can effectively restore expression of cardiac Na+ channels.
Chen S, Chen Z, Lu L, Zhao Y, Zhou R, Xie Q, Shu Y, Lin J, Yu X, Wang Y
European journal of medicinal chemistry 2023 Jul 5;255:115403
European journal of medicinal chemistry 2023 Jul 5;255:115403
GSPT1 Functions as a Tumor Promoter in Human Liver Cancer.
Xi YQ, Gao JB, Li XF, Xu LH, Li Z, Yang LJ, Wang J, Wang HQ, Fang XC, Huang SR, Xie W, Feng MH, Zhang JW
Current medical science 2023 Feb;43(1):104-114
Current medical science 2023 Feb;43(1):104-114
Degradation of neurodegenerative disease-associated TDP-43 aggregates and oligomers via a proteolysis-targeting chimera.
Tseng YL, Lu PC, Lee CC, He RY, Huang YA, Tseng YC, Cheng TR, Huang JJ, Fang JM
Journal of biomedical science 2023 Apr 26;30(1):27
Journal of biomedical science 2023 Apr 26;30(1):27
Discovery of a potent BTK and IKZF1/3 triple degrader through reversible covalent BTK PROTAC development.
Yu X, Guo WH, Lin H, Cheng R, Monroy EY, Jin F, Ding L, Lu D, Qi X, Wang MC, Wang J
Current research in chemical biology 2022;2
Current research in chemical biology 2022;2
An integrative analysis of the lncRNA-miRNA-mRNA competitive endogenous RNA network reveals potential mechanisms in the murine hair follicle cycle.
Ding Y, Chen Y, Yang X, Xu P, Jing J, Miao Y, Mao M, Xu J, Wu X, Lu Z
Frontiers in genetics 2022;13:931797
Frontiers in genetics 2022;13:931797
Overexpression of eRF3a Promotes Cell Proliferation and Migration in Liver Cancer.
Xi YQ, Xu LH, Yang LJ, Wang HQ, Yang TC, Li Z, Xie W, Zhang JW, Li XF, Feng MH
Current medical science 2022 Feb;42(1):100-107
Current medical science 2022 Feb;42(1):100-107
Hsp90 is involved in pseudorabies virus virion assembly via stabilizing major capsid protein VP5.
Zhang WJ, Wang RQ, Li LT, Fu W, Chen HC, Liu ZF
Virology 2021 Jan 15;553:70-80
Virology 2021 Jan 15;553:70-80
Long non-coding RNA LINC00511 promotes proliferation, invasion, and migration of non-small cell lung cancer cells by targeting miR-625-5p/GSPT1.
Cheng Y, Wang S, Mu X
Translational cancer research 2021 Dec;10(12):5159-5173
Translational cancer research 2021 Dec;10(12):5159-5173
A Cereblon Modulator CC-885 Induces CRBN- and p97-Dependent PLK1 Degradation and Synergizes with Volasertib to Suppress Lung Cancer.
Li L, Xue W, Shen Z, Liu J, Hu M, Cheng Z, Wang Y, Chen Y, Chang H, Liu Y, Liu B, Zhao J
Molecular therapy oncolytics 2020 Sep 25;18:215-225
Molecular therapy oncolytics 2020 Sep 25;18:215-225
Spatiotemporal Proteomic Analysis of Stress Granule Disassembly Using APEX Reveals Regulation by SUMOylation and Links to ALS Pathogenesis.
Marmor-Kollet H, Siany A, Kedersha N, Knafo N, Rivkin N, Danino YM, Moens TG, Olender T, Sheban D, Cohen N, Dadosh T, Addadi Y, Ravid R, Eitan C, Toth Cohen B, Hofmann S, Riggs CL, Advani VM, Higginbottom A, Cooper-Knock J, Hanna JH, Merbl Y, Van Den Bosch L, Anderson P, Ivanov P, Geiger T, Hornstein E
Molecular cell 2020 Dec 3;80(5):876-891.e6
Molecular cell 2020 Dec 3;80(5):876-891.e6
Downregulation of microRNA-27b-3p via aberrant DNA methylation contributes to malignant behavior of gastric cancer cells by targeting GSPT1.
Zhang C, Zou Y, Dai DQ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Nov;119:109417
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Nov;119:109417
A Novel Rac1-GSPT1 Signaling Pathway Controls Astrogliosis Following Central Nervous System Injury.
Ishii T, Ueyama T, Shigyo M, Kohta M, Kondoh T, Kuboyama T, Uebi T, Hamada T, Gutmann DH, Aiba A, Kohmura E, Tohda C, Saito N
The Journal of biological chemistry 2017 Jan 27;292(4):1240-1250
The Journal of biological chemistry 2017 Jan 27;292(4):1240-1250
A novel cereblon modulator recruits GSPT1 to the CRL4(CRBN) ubiquitin ligase.
Matyskiela ME, Lu G, Ito T, Pagarigan B, Lu CC, Miller K, Fang W, Wang NY, Nguyen D, Houston J, Carmel G, Tran T, Riley M, Nosaka L, Lander GC, Gaidarova S, Xu S, Ruchelman AL, Handa H, Carmichael J, Daniel TO, Cathers BE, Lopez-Girona A, Chamberlain PP
Nature 2016 Jul 14;535(7611):252-7
Nature 2016 Jul 14;535(7611):252-7
Polyamine stimulation of eEF1A synthesis based on the unusual position of a complementary sequence to 18S rRNA in eEF1A mRNA.
Terui Y, Sakamoto A, Yoshida T, Kasahara T, Tomitori H, Higashi K, Igarashi K, Kashiwagi K
Amino acids 2015 Feb;47(2):345-56
Amino acids 2015 Feb;47(2):345-56
Nicotine-mediated invasion and migration of non-small cell lung carcinoma cells by modulating STMN3 and GSPT1 genes in an ID1-dependent manner.
Nair S, Bora-Singhal N, Perumal D, Chellappan S
Molecular cancer 2014 Jul 16;13:173
Molecular cancer 2014 Jul 16;13:173
Mammalian hyperplastic discs homolog EDD regulates miRNA-mediated gene silencing.
Su H, Meng S, Lu Y, Trombly MI, Chen J, Lin C, Turk A, Wang X
Molecular cell 2011 Jul 8;43(1):97-109
Molecular cell 2011 Jul 8;43(1):97-109
Readthrough of nonsense mutation W822X in the SCN5A gene can effectively restore expression of cardiac Na+ channels.
Teng S, Gao L, Paajanen V, Pu J, Fan Z
Cardiovascular research 2009 Aug 1;83(3):473-80
Cardiovascular research 2009 Aug 1;83(3):473-80
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- SGC-7901 cells were subjected to SDS PAGE followed by western blot with 10763-1-AP(GSPT1 antibody) at dilution of 1:100
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GSPT1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human GSPT1. This antibody recognizes human, mouse, rat antigen. The GSPT1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.