MAB2607

antibody from R&D Systems

Targeting: GPC5

Western blot (Data presented on provider website)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

MAB2607

Provider

R&D Systems

Product name

Human/Mouse Glypican 5 Antibody

Antibody type

Monoclonal

Description

Protein A or G purified from hybridoma culture supernatant. Detects human and mouse Glypican 5 in direct ELISAs and Western blots. In direct ELISAs and Western blots, 100% cross-reactivity with recombinant mouse Glypican 5 is observed and no cross-reactivity with recombinant human Glypican 2, 3 or 6 is observed.

Reactivity

Human, Mouse

Host

Mouse

Conjugate

Unconjugated

Antigen sequence

P78333


Isotype

IgG

Antibody clone number

297716

Vial size

100 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

References

Submitted references

Heparan sulfate proteoglycans containing a glypican 5 core and 2-O-sulfo-iduronic acid function as Sonic Hedgehog co-receptors to promote proliferation.

Witt RM, Hecht ML, Pazyra-Murphy MF, Cohen SM, Noti C, van Kuppevelt TH, Fuller M, Chan JA, Hopwood JJ, Seeberger PH, Segal RA
The Journal of biological chemistry 2013 Sep 6;288(36):26275-26288

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Role for amplification and expression of glypican-5 in rhabdomyosarcoma.

Williamson D, Selfe J, Gordon T, Lu YJ, Pritchard-Jones K, Murai K, Jones P, Workman P, Shipley J
Cancer research 2007 Jan 1;67(1):57-65