Tissue expression
Cell line expression
Protein structure
UCMA
Upper zone of growth plate and cartilage matrix associatedC10orf49, GRP
This gene encodes a chondrocyte-specific, highly charged protein that is abundantly expressed in the upper immature zone of fetal and juvenile epiphyseal cartilage. The encoded protein undergoes proteolytic processing to generate a mature protein that is secreted into the extracellular matrix. The glutamic acid residues in the encoded protein undergo gamma carboxylation in a vitamin K-dependent manner. Undercarboxylation of the encoded protein is associated with osteoarthritis in humans. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2015]
Top validated antibodies |
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OriGene | AP23876PU-N | Polyclonal |
WB
EL
IHC
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Novus Biologicals | NBP1-72115 | Polyclonal |
WB
EL
IHC
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||
Acris Antibodies GmbH | AP23876PU-N | Polyclonal |
WB
EL
IHC
|
||
Biorbyt | orb2195715 | Polyclonal |
WB
EL
IHC
|
||
Abnova Corporation | PAB16758 | 2 references | Polyclonal |
WB
|
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Supportive data in Antibodypedia
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Recommended by provider