BS8239

antibody from Bioworld Technology, Inc

Targeting: PTRH2 BIT1, CFAP37, CGI-147, PTH2

Immunohistochemistry

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Validation data

Product number: BS8239 - Provider product page
Provider: Bioworld Technology, Inc
Product name: PTRH2 polyclonal antibody
Antibody type: Polyclonal
Antigen: Recombinant full length Human PTRH2.
Description: PTRH2 (peptidyl-tRNA hydrolase 2), also known as BIT1 (Bcl-2 inhibitor of transcription 1), is a 179 amino acid mitochondrial protein. During apoptosis, PTRH2 is released from the mitochondia to the cytoplasm. Once in the cytoplasm, PTRH2 regulates the function of two transcriptional regulators, TLE5 and TLE1, thereby promoting caspase-independent cell death. It is also believed that the natural substrate for PTRH2 may be petidyl-tRNAs, which leave the ribosomes during protein synthesis. PTRH2 is a monomer that contains a N-terminal mitochondrial localization signal and a C-terminal UPF0099 domain.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

PTRH2 protein structure - BS8239 shown in red.