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- Antibody Data
- Antigen structure
- References [13]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
- Flow cytometry [1]
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- Product number
- 14920-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14920-1-AP, RRID:AB_2243302
- Product name
- ATP6V1D antibody
- Antibody type
- Polyclonal
- Description
- ATP6V1D antibody (Cat. #14920-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references E3 ligase AREL1 controls perinuclear localization of lysosomes and supports Purkinje cell survival.
Trans-Golgi network-associated noncanonical autophagy depends on the V-ATPase-ATG16L1 axis and mediates IL1B secretion.
A heterotrimeric protein complex assembles the metazoan V-ATPase upon dissipation of proton gradients.
Nonreceptor tyrosine kinase ABL1 regulates lysosomal acidification by phosphorylating the ATP6V1B2 subunit of the vacuolar-type H(+)-ATPase.
Cell-Type Resolved Protein Atlas of Brain Lysosomes Identifies SLC45A1-Associated Disease as a Lysosomal Disorder.
Diphyllin elicits a doubled-pronged attack on the entry of SARS-CoV-2 by inhibiting cathepsin L and furin.
Tangshen formula protects against podocyte apoptosis via enhancing the TFEB-mediated autophagy-lysosome pathway in diabetic nephropathy.
Missing WD40 Repeats in ATG16L1 Delays Canonical Autophagy and Inhibits Noncanonical Autophagy.
Multi-Cell Line Analysis of Lysosomal Proteomes Reveals Unique Features and Novel Lysosomal Proteins.
Inhibition of autophagy and induction of glioblastoma cell death by NEO214, a perillyl alcohol-rolipram conjugate.
Cross-linking of the endolysosomal system reveals potential flotillin structures and cargo.
The Ncoa7 locus regulates V-ATPase formation and function, neurodevelopment and behaviour.
Quantitative proteome of medulla oblongata in spontaneously hypertensive rats.
Jiang L, Tang J, Zhang YF, Zou WX, Deng G, Tian N, Zhao X, Han L, Liu K, Song BL, Luo J
The EMBO journal 2026 Feb;45(3):655-691
The EMBO journal 2026 Feb;45(3):655-691
Trans-Golgi network-associated noncanonical autophagy depends on the V-ATPase-ATG16L1 axis and mediates IL1B secretion.
Long J, Xie H, Shan H, Chen R, Zhong J, Tang J, Fang D, Wang Y, Liu P, Yin XM, Li M
Autophagy 2026 Apr;22(4):691-708
Autophagy 2026 Apr;22(4):691-708
A heterotrimeric protein complex assembles the metazoan V-ATPase upon dissipation of proton gradients.
Nardone C, Mintseris J, He D, Rutter JC, Ebert BL, Gygi SP, Rapoport T
Nature structural & molecular biology 2025 Oct;32(10):2076-2087
Nature structural & molecular biology 2025 Oct;32(10):2076-2087
Nonreceptor tyrosine kinase ABL1 regulates lysosomal acidification by phosphorylating the ATP6V1B2 subunit of the vacuolar-type H(+)-ATPase.
Song C, Dong Q, Yao Y, Cui Y, Zhang C, Lin L, Zhu L, Hu Y, Liu H, Jin Y, Li P, Liu X, Cao C
Autophagy 2025 Jun;21(6):1192-1211
Autophagy 2025 Jun;21(6):1192-1211
Cell-Type Resolved Protein Atlas of Brain Lysosomes Identifies SLC45A1-Associated Disease as a Lysosomal Disorder.
Ghoochani A, Heiby JC, Rawat ES, Medoh UN, Di Fraia D, Dong W, Gastou M, Nyame K, Laqtom NN, Gomez-Ospina N, Ori A, Abu-Remaileh M
bioRxiv : the preprint server for biology 2024 Oct 14;
bioRxiv : the preprint server for biology 2024 Oct 14;
Diphyllin elicits a doubled-pronged attack on the entry of SARS-CoV-2 by inhibiting cathepsin L and furin.
Mao B, Le-Trilling VTK, Tang H, Hu J, Schmitz MS, Barbet K, Xu D, Wei Z, Guo B, Mennerich D, Yao C, Liu J, Li Z, Wan Y, Zhang X, Wang K, Tang N, Yu Z, Trilling M, Lin Y
Virus research 2024 Dec;350:199485
Virus research 2024 Dec;350:199485
Tangshen formula protects against podocyte apoptosis via enhancing the TFEB-mediated autophagy-lysosome pathway in diabetic nephropathy.
Wang Y, Peng L, Lu X, Zhang H, Zhao H, Zhao T, Yang L, Mao H, Ma F, Liu T, Li P, Zhan Y
Journal of ethnopharmacology 2024 Apr 24;324:117721
Journal of ethnopharmacology 2024 Apr 24;324:117721
Missing WD40 Repeats in ATG16L1 Delays Canonical Autophagy and Inhibits Noncanonical Autophagy.
Tang J, Fang D, Zhong J, Li M
International journal of molecular sciences 2024 Apr 19;25(8)
International journal of molecular sciences 2024 Apr 19;25(8)
Multi-Cell Line Analysis of Lysosomal Proteomes Reveals Unique Features and Novel Lysosomal Proteins.
Akter F, Bonini S, Ponnaiyan S, Kögler-Mohrbacher B, Bleibaum F, Damme M, Renard BY, Winter D
Molecular & cellular proteomics : MCP 2023 Mar;22(3):100509
Molecular & cellular proteomics : MCP 2023 Mar;22(3):100509
Inhibition of autophagy and induction of glioblastoma cell death by NEO214, a perillyl alcohol-rolipram conjugate.
Ou M, Cho HY, Fu J, Thein TZ, Wang W, Swenson SD, Minea RO, Stathopoulos A, Schönthal AH, Hofman FM, Tang L, Chen TC
Autophagy 2023 Dec;19(12):3169-3188
Autophagy 2023 Dec;19(12):3169-3188
Cross-linking of the endolysosomal system reveals potential flotillin structures and cargo.
Singh J, Elhabashy H, Muthukottiappan P, Stepath M, Eisenacher M, Kohlbacher O, Gieselmann V, Winter D
Nature communications 2022 Oct 20;13(1):6212
Nature communications 2022 Oct 20;13(1):6212
The Ncoa7 locus regulates V-ATPase formation and function, neurodevelopment and behaviour.
Castroflorio E, den Hoed J, Svistunova D, Finelli MJ, Cebrian-Serrano A, Corrochano S, Bassett AR, Davies B, Oliver PL
Cellular and molecular life sciences : CMLS 2021 Apr;78(7):3503-3524
Cellular and molecular life sciences : CMLS 2021 Apr;78(7):3503-3524
Quantitative proteome of medulla oblongata in spontaneously hypertensive rats.
Sun D, Cheng Y, Zhou D, Liu T, Chen S, Liang J, Tang C, Lai X
Journal of proteome research 2013 Jan 4;12(1):390-5
Journal of proteome research 2013 Jan 4;12(1):390-5
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 14920-1-AP(ATP6V1D antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human lung cancer using 14920-1-AP(ATP6V1D antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human lung cancer using 14920-1-AP(ATP6V1D antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ATP6V1D antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ATP6V1D. This antibody recognizes human,mouse,rat antigen. The ATP6V1D antibody has been validated for the following applications: ELISA, WB, IHC, FC analysis.
