Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 22028-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#22028-1-AP, RRID:AB_11183760
- Product name
- PIK3C2A antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PIK3C2A antibody (Cat. #22028-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Cezanne promoted autophagy through PIK3C3 stabilization and PIK3C2A transcription in lung adenocarcinoma.
Kinase-independent synthesis of 3-phosphorylated phosphoinositides by a phosphotransferase.
Phosphoinositide Conversion Inactivates R-RAS and Drives Metastases in Breast Cancer.
The Role of Tim-3 on dNK Cells Dysfunction During Abnormal Pregnancy With Toxoplasma gondii Infection.
Defining endogenous TACC3-chTOG-clathrin-GTSE1 interactions at the mitotic spindle using induced relocalization.
PI(3,4)P2-mediated cytokinetic abscission prevents early senescence and cataract formation.
Mitotic Spindle Assembly and Genomic Stability in Breast Cancer Require PI3K-C2α Scaffolding Function.
Phosphatidylinositol 3,4-bisphosphate regulates neurite initiation and dendrite morphogenesis via actin aggregation.
A four-gene signature predicts survival in clear-cell renal-cell carcinoma.
Wang Y, Li J, Zheng H, Wang K, Ren X, Wang G, Du J
Cell death discovery 2023 Aug 18;9(1):302
Cell death discovery 2023 Aug 18;9(1):302
Kinase-independent synthesis of 3-phosphorylated phosphoinositides by a phosphotransferase.
Walpole GFW, Pacheco J, Chauhan N, Clark J, Anderson KE, Abbas YM, Brabant-Kirwan D, Montaño-Rendón F, Liu Z, Zhu H, Brumell JH, Deiters A, Stephens LR, Hawkins PT, Hammond GRV, Grinstein S, Fairn GD
Nature cell biology 2022 May;24(5):708-722
Nature cell biology 2022 May;24(5):708-722
Phosphoinositide Conversion Inactivates R-RAS and Drives Metastases in Breast Cancer.
Li H, Prever L, Hsu MY, Lo WT, Margaria JP, De Santis MC, Zanini C, Forni M, Novelli F, Pece S, Di Fiore PP, Porporato PE, Martini M, Belabed H, Nazare M, Haucke V, Gulluni F, Hirsch E
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Mar;9(9):e2103249
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Mar;9(9):e2103249
The Role of Tim-3 on dNK Cells Dysfunction During Abnormal Pregnancy With Toxoplasma gondii Infection.
Li T, Cui L, Xu X, Zhang H, Jiang Y, Ren L, Yang C, Liu X, Hu X
Frontiers in cellular and infection microbiology 2021;11:587150
Frontiers in cellular and infection microbiology 2021;11:587150
Defining endogenous TACC3-chTOG-clathrin-GTSE1 interactions at the mitotic spindle using induced relocalization.
Ryan EL, Shelford J, Massam-Wu T, Bayliss R, Royle SJ
Journal of cell science 2021 Feb 1;134(3)
Journal of cell science 2021 Feb 1;134(3)
PI(3,4)P2-mediated cytokinetic abscission prevents early senescence and cataract formation.
Gulluni F, Prever L, Li H, Krafcikova P, Corrado I, Lo WT, Margaria JP, Chen A, De Santis MC, Cnudde SJ, Fogerty J, Yuan A, Massarotti A, Sarijalo NT, Vadas O, Williams RL, Thelen M, Powell DR, Schueler M, Wiesener MS, Balla T, Baris HN, Tiosano D, McDermott BM Jr, Perkins BD, Ghigo A, Martini M, Haucke V, Boura E, Merlo GR, Buchner DA, Hirsch E
Science (New York, N.Y.) 2021 Dec 10;374(6573):eabk0410
Science (New York, N.Y.) 2021 Dec 10;374(6573):eabk0410
Mitotic Spindle Assembly and Genomic Stability in Breast Cancer Require PI3K-C2α Scaffolding Function.
Gulluni F, Martini M, De Santis MC, Campa CC, Ghigo A, Margaria JP, Ciraolo E, Franco I, Ala U, Annaratone L, Disalvatore D, Bertalot G, Viale G, Noatynska A, Compagno M, Sigismund S, Montemurro F, Thelen M, Fan F, Meraldi P, Marchiò C, Pece S, Sapino A, Chiarle R, Di Fiore PP, Hirsch E
Cancer cell 2017 Oct 9;32(4):444-459.e7
Cancer cell 2017 Oct 9;32(4):444-459.e7
Phosphatidylinositol 3,4-bisphosphate regulates neurite initiation and dendrite morphogenesis via actin aggregation.
Zhang SX, Duan LH, He SJ, Zhuang GF, Yu X
Cell research 2017 Feb;27(2):253-273
Cell research 2017 Feb;27(2):253-273
A four-gene signature predicts survival in clear-cell renal-cell carcinoma.
Dai J, Lu Y, Wang J, Yang L, Han Y, Wang Y, Yan D, Ruan Q, Wang S
Oncotarget 2016 Dec 13;7(50):82712-82726
Oncotarget 2016 Dec 13;7(50):82712-82726
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- PC-3 cells were subjected to SDS PAGE followed by western blot with 22028-1-AP(PIK3C2A antibody) at dilution of 1:1500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human heart using 22028-1-AP(PIK3C2A antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PIK3C2A antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human PIK3C2A. This antibody recognizes human, mouse antigen. The PIK3C2A antibody has been validated for the following applications: ELISA, WB, IHC analysis.