Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 11267-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11267-1-AP, RRID:AB_2288787
- Product name
- XRN2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated XRN2 antibody (Cat. #11267-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references DDX21 mediates co-transcriptional RNA m(6)A modification to promote transcription termination and genome stability.
R-Loop Immunoprecipitation: A Method to Detect R-Loop Interacting Factors.
Divergent transcriptional regulation of astrocyte reactivity across disorders.
Arginine methylation of the DDX5 helicase RGG/RG motif by PRMT5 regulates resolution of RNA:DNA hybrids.
Intronless mRNAs transit through nuclear speckles to gain export competence.
Characterization of miR-122-independent propagation of HCV.
Dissecting the roles of the 5' exoribonucleases Xrn1 and Xrn2 in restricting hepatitis C virus replication.
Microprocessor, Setx, Xrn2, and Rrp6 co-operate to induce premature termination of transcription by RNAPII.
Hao JD, Liu QL, Liu MX, Yang X, Wang LM, Su SY, Xiao W, Zhang MQ, Zhang YC, Zhang L, Chen YS, Yang YG, Ren J
Molecular cell 2024 May 2;84(9):1711-1726.e11
Molecular cell 2024 May 2;84(9):1711-1726.e11
R-Loop Immunoprecipitation: A Method to Detect R-Loop Interacting Factors.
Beghè C, Gromak N
Methods in molecular biology (Clifton, N.J.) 2022;2528:215-237
Methods in molecular biology (Clifton, N.J.) 2022;2528:215-237
Divergent transcriptional regulation of astrocyte reactivity across disorders.
Burda JE, O'Shea TM, Ao Y, Suresh KB, Wang S, Bernstein AM, Chandra A, Deverasetty S, Kawaguchi R, Kim JH, McCallum S, Rogers A, Wahane S, Sofroniew MV
Nature 2022 Jun;606(7914):557-564
Nature 2022 Jun;606(7914):557-564
Arginine methylation of the DDX5 helicase RGG/RG motif by PRMT5 regulates resolution of RNA:DNA hybrids.
Mersaoui SY, Yu Z, Coulombe Y, Karam M, Busatto FF, Masson JY, Richard S
The EMBO journal 2019 Aug 1;38(15):e100986
The EMBO journal 2019 Aug 1;38(15):e100986
Intronless mRNAs transit through nuclear speckles to gain export competence.
Wang K, Wang L, Wang J, Chen S, Shi M, Cheng H
The Journal of cell biology 2018 Nov 5;217(11):3912-3929
The Journal of cell biology 2018 Nov 5;217(11):3912-3929
Characterization of miR-122-independent propagation of HCV.
Ono C, Fukuhara T, Motooka D, Nakamura S, Okuzaki D, Yamamoto S, Tamura T, Mori H, Sato A, Uemura K, Fauzyah Y, Kurihara T, Suda T, Nishio A, Hmwe SS, Okamoto T, Tatsumi T, Takehara T, Chayama K, Wakita T, Koike K, Matsuura Y
PLoS pathogens 2017 May;13(5):e1006374
PLoS pathogens 2017 May;13(5):e1006374
Dissecting the roles of the 5' exoribonucleases Xrn1 and Xrn2 in restricting hepatitis C virus replication.
Li Y, Yamane D, Lemon SM
Journal of virology 2015 May;89(9):4857-65
Journal of virology 2015 May;89(9):4857-65
Microprocessor, Setx, Xrn2, and Rrp6 co-operate to induce premature termination of transcription by RNAPII.
Wagschal A, Rousset E, Basavarajaiah P, Contreras X, Harwig A, Laurent-Chabalier S, Nakamura M, Chen X, Zhang K, Meziane O, Boyer F, Parrinello H, Berkhout B, Terzian C, Benkirane M, Kiernan R
Cell 2012 Sep 14;150(6):1147-57
Cell 2012 Sep 14;150(6):1147-57
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The XRN2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human XRN2. This antibody recognizes human, mouse, rat antigen. The XRN2 antibody has been validated for the following applications: ELISA, WB analysis.