ABCC8

gene product
ABC36, HHF1, HI, HRINS, MRP8, PHHI, SUR, SUR1, TNDM2
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy, an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II, an autosomal dominant disease of defective insulin secretion. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2013]
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288 antibodies from 32 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
84 antibodies
Novus Biologicals
26 antibodies
Boster Biological Technology
3 antibodies
Affinity Biosciences
1 antibody
LifeSpan BioSciences, Inc.
46 antibodies
Biorbyt
14 antibodies
Invitrogen Antibodies
4 antibodies
NSJ Bioreagents
2 antibodies
OriGene
4 antibodies
Aviva Systems Biology
2 antibodies
Atlas Antibodies
1 antibody
UC Davis/NIH NeuroMab Facility
6 antibodies
NovoPro Bioscience Inc.
2 antibodies
Abgent
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Antibodies.com
1 antibody
Acris Antibodies GmbH
3 antibodies
Everest Biotech
1 antibody
Abnova Corporation
6 antibodies
MyBioSource
5 antibodies
FabGennix
3 antibodies
Arigo
1 antibody
GeneTex
1 antibody
Creative Biolabs
17 antibodies
St John's Laboratory
3 antibodies
Creative Diagnostics
4 antibodies
ProSci
1 antibody
RayBiotech, Inc.
1 antibody
United States Biological
26 antibodies
Sigma-Aldrich
3 antibodies
EMD Millipore
2 antibodies