AMM02101G

antibody from Leading Biology

Targeting: CYBB CGD, GP91-PHOX, NOX2

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

AMM02101G

Provider

Leading Biology

Product name

NOX2 / gp91phox Antibody (clone 48)

Antibody type

Monoclonal

Description

Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc.

Reactivity

Human

Host

Mouse

Antibody clone number

48

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.