PA1667

antibody from Boster Biological Technology

Targeting: CYBB CGD, GP91-PHOX, NOX2

Provider product page for PA1667

Western blot

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [22]
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Validations
Western blot [1]

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Product number: PA1667 - Provider product page
Provider: Boster Biological Technology
Product name: Anti-NOX2/gp91phox/CYBB Antibody
Antibody type: Polyclonal
Description: Polyclonal antibody for NOX2/CYBB detection. Host: Rabbit.Size: 100μg/vial. Tested applications: IHC-P. Reactive species: Human. NOX2/CYBB information: Molecular Weight: 65336 MW; Subcellular Localization: Cell membrane; Multi-pass membrane protein; Tissue Specificity: Detected in neutrophils (at protein level).
Reactivity: Human, Mouse, Rat
Host: Rabbit
Vial size: 100μg/vial
Concentration: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage: At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquoted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Handling: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

CYBB protein structure - PA1667 shown in red.

Submitted references Tanshinone IIA inhibited intermittent hypoxia induced neuronal injury through promoting autophagy via AMPK-mTOR signaling pathway.

Si J, Liu B, Qi K, Chen X, Li D, Yang S, Ji E
Journal of ethnopharmacology 2023 Oct 28;315:116677

TIPE1 promotes liver regeneration by enhancing ROS-FoxO1 axis mediated autophagy.

Zhang X, Li S, Ren X, Xiang P, Zhang Y, Wang T, Qin Q, Sun F, Liu J, Gao L, Ma C, Yue X, Yang X, Han S, Liang X
The FEBS journal 2023 Feb;290(4):1117-1133

Secretome of hESC-Derived MSC-like Immune and Matrix Regulatory Cells Mitigate Pulmonary Fibrosis through Antioxidant and Anti-Inflammatory Effects.

Hu W, Yang J, Xue J, Ma J, Wu S, Wang J, Xu R, Wei J, Wang Y, Wang S, Liu X
Biomedicines 2023 Feb 5;11(2)

Identification of Resolvin D1 and Protectin D1 as Potential Therapeutic Agents for Treating Kidney Stones.

Wang B, Wei J, Huangfu Q, Gao F, Qin L, Zhong J, Wen J, Ye Z, Yang X, Liu H
Oxidative medicine and cellular longevity 2022;2022:4345037

Therapeutic Potential of Astragaloside IV Against Adriamycin-Induced Renal Damage in Rats via Ferroptosis.

Qin LY, Guan P, Wang JX, Chen Y, Zhao YS, Yang SC, Guo YJ, Wang N, Ji ES
Frontiers in pharmacology 2022;13:812594

Prenatal hypothyroidism diminished exogenous NO-mediated diastolic effects in fetal rat thoracic aorta smooth muscle via increased oxidative stress.

Guo J, Yu X, Liu Y, Lu L, Zhu D, Zhang Y, Li L, Zhang P, Gao Q, Lu X, Sun M
Reproductive toxicology (Elmsford, N.Y.) 2022 Oct;113:52-61

Potential cardioprotective effect of octreotide via NOXs mitigation, mitochondrial biogenesis and MAPK/Erk1/2/STAT3/NF-kβ pathway attenuation in isoproterenol-induced myocardial infarction in rats.

Khalifa AA, El Sokkary NH, Elblehi SS, Diab MA, Ali MA
European journal of pharmacology 2022 Jun 15;925:174978

The role of reactive oxygen species derived from different NADPH oxidase isoforms and mitochondria in oxalate-induced oxidative stress and cell injury.

Qian X, Wu W, Hu H, Yu X, Wang S, Zhu J, Zhang J
Urolithiasis 2022 Apr;50(2):149-158

XIST Inhibition Attenuates Calcium Oxalate Nephrocalcinosis-Induced Renal Inflammation and Oxidative Injury via the miR-223/NLRP3 Pathway.

Lv P, Liu H, Ye T, Yang X, Duan C, Yao X, Li B, Tang K, Chen Z, Liu J, Deng Y, Wang T, Xing J, Liang C, Xu H, Ye Z
Oxidative medicine and cellular longevity 2021;2021:1676152

Theaflavin protects against oxalate calcium-induced kidney oxidative stress injury via upregulation of SIRT1.

Ye T, Yang X, Liu H, Lv P, Lu H, Jiang K, Peng E, Ye Z, Chen Z, Tang K
International journal of biological sciences 2021;17(4):1050-1060

Fetal e-cigarette exposure programs a neonatal brain hypoxic-ischemic sensitive phenotype via altering DNA methylation patterns and autophagy signaling pathway.

Walayat A, Li Y, Zhang Y, Fu Y, Liu B, Shao XM, Zhang L, Xiao D
American journal of physiology. Regulatory, integrative and comparative physiology 2021 Nov 1;321(5):R791-R801

The Protective Roles of Estrogen Receptor β in Renal Calcium Oxalate Crystal Formation via Reducing the Liver Oxalate Biosynthesis and Renal Oxidative Stress-Mediated Cell Injury.

Zhu W, Zhao Z, Chou FJ, Zuo L, Liu T, Bushinsky D, Chang C, Zeng G, Yeh S
Oxidative medicine and cellular longevity 2019;2019:5305014

Epigenetic Down-Regulation of Sirt 1 via DNA Methylation and Oxidative Stress Signaling Contributes to the Gestational Diabetes Mellitus-Induced Fetal Programming of Heart Ischemia-Sensitive Phenotype in Late Life.

Chen Z, Gong L, Zhang P, Li Y, Liu B, Zhang L, Zhuang J, Xiao D
International journal of biological sciences 2019;15(6):1240-1251

Renal and cerebral RAS interaction contributes to diabetic kidney disease.

Liu Y, Li L, Qiu M, Tan L, Zhang M, Li J, Zhu H, Jiang S, Su X, Li A
American journal of translational research 2019;11(5):2925-2939

Increased Tim-3 expression alleviates liver injury by regulating macrophage activation in MCD-induced NASH mice.

Du X, Wu Z, Xu Y, Liu Y, Liu W, Wang T, Li C, Zhang C, Yi F, Gao L, Liang X, Ma C
Cellular & molecular immunology 2019 Nov;16(11):878-886

H19 promote calcium oxalate nephrocalcinosis-induced renal tubular epithelial cell injury via a ceRNA pathway.

Liu H, Ye T, Yang X, Liu J, Jiang K, Lu H, Xia D, Peng E, Chen Z, Sun F, Tang K, Ye Z
EBioMedicine 2019 Dec;50:366-378

Wnt/β-catenin links oxidative stress to podocyte injury and proteinuria.

Zhou L, Chen X, Lu M, Wu Q, Yuan Q, Hu C, Miao J, Zhang Y, Li H, Hou FF, Nie J, Liu Y
Kidney international 2019 Apr;95(4):830-845

Dietary phytol reduces clinical symptoms in experimental autoimmune encephalomyelitis (EAE) at least partially by modulating NOX2 expression.

Blum L, Tafferner N, Spring I, Kurz J, deBruin N, Geisslinger G, Parnham MJ, Schiffmann S
Journal of molecular medicine (Berlin, Germany) 2018 Oct;96(10):1131-1144

C1q/tumor necrosis factor-related protein 3 inhibits oxidative stress during intracerebral hemorrhage via PKA signaling.

Yang B, Wang S, Yu S, Chen Y, Li L, Zhang H, Zhao Y
Brain research 2017 Feb 15;1657:176-184

NADPH oxidase 2-dependent oxidative stress, mitochondrial damage and apoptosis in the ventral cochlear nucleus of D-galactose-induced aging rats.

Du Z, Yang Q, Liu L, Li S, Zhao J, Hu J, Liu C, Qian D, Gao C
Neuroscience 2015 Feb 12;286:281-92

D‑galactose‑induced mitochondrial DNA oxidative damage in the auditory cortex of rats.

Du Z, Yang Q, Zhou T, Liu L, Li S, Chen S, Gao C
Molecular medicine reports 2014 Dec;10(6):2861-7

Effects of quercetin on gene and protein expression of NOX and NOS after myocardial ischemia and reperfusion in rabbit.

Wan LL, Xia J, Ye D, Liu J, Chen J, Wang G
Cardiovascular therapeutics 2009 Spring;27(1):28-33

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Submitted by: Boster Biological Technology (provider)
Main image
Experimental details: Anti-NOX2/gp91phox antibody, PA1667, Western blottingLane 1: HELA Cell Lysate Lane 2: JURKAT Cell LysateLane 3: MCF-7 Cell Lysate Lane 4: SMMC Cell Lysate
Additional image