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- Antigen structure
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- Product number
- 19013-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- NOX2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated NOX2 antibody (Cat. #19013-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Reversal of cholestatic liver disease by the inhibition of sphingosine 1-phosphate receptor 2 signaling.
NOX2 and NOX4 expression in monocytes and macrophages-extracellular vesicles in signalling and therapeutics.
Inhibition of MST1 ameliorates neuronal apoptosis via GSK3β/β-TrCP/NRF2 pathway in spinal cord injury accompanied by diabetes.
Food therapy of scutellarein ameliorates pirarubicin‑induced cardiotoxicity in rats by inhibiting apoptosis and ferroptosis through regulation of NOX2‑induced oxidative stress.
Caffeic acid phenethyl ester inhibits neuro-inflammation and oxidative stress following spinal cord injury by mitigating mitochondrial dysfunction via the SIRT1/PGC1α/DRP1 signaling pathway.
FGF21 Inhibits Hypoxia/Reoxygenation-induced Renal Tubular Epithelial Cell Injury by Regulating the PPARγ/NF-κB Signaling Pathway.
Intracellular and extracellular Cyclophilin a promote cardiac fibrosis through TGF-β signaling in response to angiotensin Ⅱ.
Nicotinamide mononucleotide attenuates airway epithelial barrier dysfunction via inhibiting SIRT3 SUMOylation in asthma.
The antihypertensive effect of Alizarin is achieved by activating VEGFR2/eNOS pathway, attenuating oxidative stress-induced mitochondrial damage and premature senescence.
Mitochondrial complex I activity in microglia sustains neuroinflammation.
CYBB-Mediated Ferroptosis Associated with Immunosuppression in Mycobacterium leprae-Infected Monocyte-Derived Macrophages.
GKT137831 in combination with adipose-derived stem cells alleviates high glucose-induced inflammaging and improves diabetic wound healing.
Sphingolipid biosynthesis is essential for metabolic rewiring during T(H)17 cell differentiation.
Esculin targets TLR4 to protect against LPS-induced septic cardiomyopathy.
Nox2 inhibition reduces trophoblast ferroptosis in preeclampsia via the STAT3/GPX4 pathway.
Antigen stasis and airway nitrosative stress in human primary ciliary dyskinesia.
Adipocyte-Derived Exosomal NOX4-Mediated Oxidative Damage Induces Premature Placental Senescence in Obese Pregnancy.
Effects of liraglutide on astrocyte polarization and neuroinflammation in db/db mice: focus on iron overload and oxidative stress.
Identification and validation of immune-associated NETosis subtypes and biomarkers in anti-neutrophil cytoplasmic antibody associated glomerulonephritis.
FGL2 deficiency alleviates maternal inflammation-induced blood-brain barrier damage by blocking PI3K/NF-κB mediated endothelial oxidative stress.
Oscillatory shear stress promotes vein graft intimal hyperplasia via NADPH oxidase-related pathways.
Pure total flavonoids from citrus alleviate oxidative stress and inflammation in nonalcoholic fatty liver disease by regulating the miR-137-3p/NOXA2/NOX2 pathway.
A Novel NOX Inhibitor Alleviates Parkinson's Disease Pathology in PFF-Injected Mice.
Inhibition of AT1R/IP3/IP3R-mediated Ca(2+) release protects against calcium oxalate crystals-induced renal oxidative stress.
Niclosamide Inhibits Aortic Valve Interstitial Cell Calcification by Interfering with the GSK-3β/β-Catenin Signaling Pathway.
Transient receptor potential vanilloid 4 (TRPV4) in neutrophils enhances myocardial ischemia/reperfusion injury.
Glucocorticoid-induced activation of NOX/ROS/NF-κB signaling in MSCs contributes to the development of GONFH.
Intermittent fasting alleviates type 1 diabetes-induced cognitive dysfunction by improving the frontal cortical metabolic disorder.
The novel peptide athycaltide-1 attenuates Ang II-induced pathological myocardial hypertrophy by reducing ROS and inhibiting the activation of CaMKII and ERK1/2.
Colchicine protects against the development of experimental abdominal aortic aneurysm.
Short-chain acyl-CoA dehydrogenase is a potential target for the treatment of vascular remodelling.
Electroacupuncture alleviates early brain injury via modulating microglia polarization and suppressing neuroinflammation in a rat model of subarachnoid hemorrhage.
Lnc-17Rik promotes the immunosuppressive function of Myeloid-Derived suppressive cells in esophageal cancer.
Dioscin ameliorates silica-aggravated systemic lupus erythematosus via suppressing apoptosis and improving LC3-associated phagocytosis in MRL/lpr mice.
Capsaicin inhibits aortic valvular interstitial cell calcification via the redox-sensitive NFκB/AKT/ERK1/2 pathway.
Synergistic effect of elevated glucose levels with SARS-CoV-2 spike protein induced NOX-dependent ROS production in endothelial cells.
The pro-inflammatory signature of lipopolysaccharide in spontaneous contracting embryoid bodies differentiated from mouse embryonic stem cells.
Contemporary Antiretroviral Therapy Dysregulates Iron Transport and Augments Mitochondrial Dysfunction in HIV-Infected Human Microglia and Neural-Lineage Cells.
Dysregulated B7H4/JAK2/STAT3 Pathway Involves in Hypertriglyceridemia Acute Pancreatitis and Is Attenuated by Baicalin.
Stromal Vascular Fraction Restores Vasodilatory Function by Reducing Oxidative Stress in Aging-Induced Coronary Microvascular Disease.
Saxagliptin alleviates erectile dysfunction through increasing stromal cell-derived factor-1 in diabetes mellitus.
Acid sphingomyelinase promotes diabetic cardiomyopathy via NADPH oxidase 4 mediated apoptosis.
Adrenomedullin Improves Hypertension and Vascular Remodeling partly through the Receptor-Mediated AMPK Pathway in Rats with Obesity-Related Hypertension.
Exosomal RBP4 potentiated hepatic lipid accumulation and inflammation in high-fat-diet-fed mice by promoting M1 polarization of Kupffer cells.
Apolipoprotein C-III itself stimulates the Syk/cPLA2-induced inflammasome activation of macrophage to boost anti-tumor activity of CD8(+) T cell.
Nogo-B mediates endothelial oxidative stress and inflammation to promote coronary atherosclerosis in pressure-overloaded mouse hearts.
Comprehensive analysis and identification of prognostic biomarkers and immunotherapeutic targets in the NADPH oxidase family (and its regulatory subunits) in pancreatic ductal adenocarcinoma.
BMP4 inhibits corneal neovascularization by interfering with tip cells in angiogenesis.
Fibroblast growth factor 21 protects the liver from apoptosis in a type 1 diabetes mouse model via regulating L-lactate homeostasis.
Purinergic receptor P2X7 activates NOX2/JNK signaling to participate in granulosa cell inflammation and apoptosis in polycystic ovary syndrome.
Angiotensin II Increases Oxidative Stress and Inflammation in Female, But Not Male, Endothelial Cells.
SGLT2 inhibition ameliorates nano plastics-induced premature endothelial senescence and dysfunction.
Aerobic Exercise Training Improves Renal Injury in Spontaneously Hypertensive Rats by Increasing Renalase Expression in Medulla.
Lonicera caerulea Berry Polyphenols Extract Alleviates Exercise Fatigue in Mice by Reducing Oxidative Stress, Inflammation, Skeletal Muscle Cell Apoptosis, and by Increasing Cell Proliferation.
Recurrent Hypoglycemia Impaired Vascular Function in Advanced T2DM Rats by Inducing Pyroptosis.
Schisandrin B Diet Inhibits Oxidative Stress to Reduce Ferroptosis and Lipid Peroxidation to Prevent Pirarubicin-Induced Hepatotoxicity.
Angiotensin II Induces Cardiac Edema and Hypertrophic Remodeling through Lymphatic-Dependent Mechanisms.
Soluble Epoxide Hydrolase Inhibition Protected against Diabetic Cardiomyopathy through Inducing Autophagy and Reducing Apoptosis Relying on Nrf2 Upregulation and Transcription Activation.
Change in Oxidative Stress and Mitochondrial Dynamics in Response to Elevated Cold-Inducible RNA-Binding Protein in Cardiac Surgery-Associated Acute Kidney Injury.
Pyrrosia petiolosa Extract Ameliorates Ethylene Glycol-Induced Urolithiasis in Rats by Inhibiting Oxidative Stress and Inflammatory Response.
Rosmarinic Acid Ameliorates Pulmonary Ischemia/Reperfusion Injury by Activating the PI3K/Akt Signaling Pathway.
A Novel Compound, Tanshinol Borneol Ester, Ameliorates Pressure Overload-Induced Cardiac Hypertrophy by Inhibiting Oxidative Stress via the mTOR/β-TrCP/NRF2 Pathway.
Administration of USP7 inhibitor P22077 inhibited cardiac hypertrophy and remodeling in Ang II-induced hypertensive mice.
A dual Keap1 and p47(phox) inhibitor Ginsenoside Rb1 ameliorates high glucose/ox-LDL-induced endothelial cell injury and atherosclerosis.
Combination Treatment with Hydroxytyrosol and Vitamin E Improves NAFLD-Related Fibrosis.
Edaravone dexborneol protects cerebral ischemia reperfusion injury through activating Nrf2/HO-1 signaling pathway in mice.
Inhibition of Hypoxia-Inducible Factor Prolyl-Hydroxylase Modulates Platelet Function.
Suramin enhances chondrogenic properties by regulating the p67(phox)/PI3K/AKT/SOX9 signalling pathway.
Mycobacterium tuberculosis Utilizes Host Histamine Receptor H1 to Modulate Reactive Oxygen Species Production and Phagosome Maturation via the p38MAPK-NOX2 Axis.
Identification of a necroptosis-related prognostic gene signature associated with tumor immune microenvironment in cervical carcinoma and experimental verification.
Gut microbiome dysbiosis contributes to abdominal aortic aneurysm by promoting neutrophil extracellular trap formation.
The Clostridium Metabolite P-Cresol Sulfate Relieves Inflammation of Primary Biliary Cholangitis by Regulating Kupffer Cells.
Lipopolysaccharide induces placental mitochondrial dysfunction in murine and human systems by reducing MNRR1 levels via a TLR4-independent pathway.
Graphene oxide leads to mitochondrial-dependent apoptosis by activating ROS-p53-mPTP pathway in intestinal cells.
Impact of Selective Renal Afferent Denervation on Oxidative Stress and Vascular Remodeling in Spontaneously Hypertensive Rats.
Pu-erh Tea Restored Circadian Rhythm Disruption by Regulating Tryptophan Metabolism.
Prednisone Ameliorates Atrial Inflammation and Fibrosis in Atrial Tachypacing Dogs.
Effects of polystyrene nanoplastics on endothelium senescence and its underlying mechanism.
Disruption of mitochondrial redox homeostasis as a mechanism of antimony-induced reactive oxygen species and cytotoxicity.
In utero hypoxia attenuated acetylcholine-mediated vasodilatation via CHRM3/p-NOS3 in fetal sheep MCA: role of ROS/ERK1/2.
Accumulation of advanced oxidation protein products contributes to age-related impairment of gap junction intercellular communication in osteocytes of male mice.
Role of Nox4 in High Calcium-Induced Renal Oxidative Stress Damage and Crystal Deposition.
Reducing oxidative stress may be important for treating pirarubicin-induced cardiotoxicity with schisandrin B.
mTORC1 activation induced proximal tubular damage via the pentose phosphate pathway in lupus nephritis.
Chronic Sigma 1 receptor activation alleviates right ventricular dysfunction secondary to pulmonary arterial hypertension.
Honokiol improves endothelial function in type 2 diabetic rats via alleviating oxidative stress and insulin resistance.
A Novel NOX Inhibitor Treatment Attenuates Parkinson's Disease-Related Pathology in Mouse Models.
Electronic cigarette exposure causes vascular endothelial dysfunction due to NADPH oxidase activation and eNOS uncoupling.
Crocin Improves Endothelial Mitochondrial Dysfunction via GPx1/ROS/KCa3.1 Signal Axis in Diabetes.
Human Tissue Kallikrein 1 Is Downregulated in Elderly Human Prostates and Possesses Potential In Vitro Antioxidative and Antifibrotic Effects in Rodent Prostates.
Shenxian-Shengmai Oral Liquid Improves Sinoatrial Node Dysfunction through the PKC/NOX-2 Signaling Pathway.
Microglia-Derived Exosomes Improve Spinal Cord Functional Recovery after Injury via Inhibiting Oxidative Stress and Promoting the Survival and Function of Endothelia Cells.
17β-Estradiol promotes LC3B-associated phagocytosis in trained immunity of female mice against sepsis.
Iron Oxide Nanoparticles Combined with Cytosine Arabinoside Show Anti-Leukemia Stem Cell Effects on Acute Myeloid Leukemia by Regulating Reactive Oxygen Species.
Nox2 contributes to reactive oxygen species-induced redox imbalance in cancer-induced bone pain.
Nox2 impairs VEGF-A-induced angiogenesis in placenta via mitochondrial ROS-STAT3 pathway.
Compound essential oils relieve oxidative stress caused by PM(2) (.5) exposure by inhibiting autophagy through the AMPK/mTOR pathway.
Effects of different intensities of continuous training on vascular inflammation and oxidative stress in spontaneously hypertensive rats.
Aged Ripe Pu-erh Tea Reduced Oxidative Stress-Mediated Inflammation in Dextran Sulfate Sodium-Induced Colitis Mice by Regulating Intestinal Microbes.
Canagliflozin is a potential cardioprotective drug but exerts no significant effects on pirarubicin‑induced cardiotoxicity in rats.
The protective effect of harpagoside on angiotensin II (Ang II)-induced blood-brain barrier leakage in vitro.
Distinction between 2'- and 3'-Phosphate Isomers of a Fluorescent NADPH Analogue Led to Strong Inhibition of Cancer Cells Migration.
Mild hypothermia in rat with acute myocardial ischaemia-reperfusion injury complicating severe sepsis.
Protective effect of recombinant Lactobacillus plantarum against H(2)O(2)-induced oxidative stress in HUVEC cells.
C-C motif ligand 8 promotes atherosclerosis via NADPH oxidase 2/reactive oxygen species-induced endothelial permeability increase.
Sirtuin 1 ameliorates defenestration in hepatic sinusoidal endothelial cells during liver fibrosis via inhibiting stress-induced premature senescence.
Scoparone alleviates Ang II-induced pathological myocardial hypertrophy in mice by inhibiting oxidative stress.
Hsa_circ_0005915 promotes N,N-dimethylformamide-induced oxidative stress in HL-7702 cells through NRF2/ARE axis.
Protective effect of scorpion venom heat-resistant synthetic peptide against PM(2.5)-induced microglial polarization via TLR4-mediated autophagy activating PI3K/AKT/NF-κB signaling pathway.
Silencing COX-2 blocks PDK1/TRAF4-induced AKT activation to inhibit fibrogenesis during skeletal muscle atrophy.
Normothermic machine perfusion attenuates hepatic ischaemia-reperfusion injury by inhibiting CIRP-mediated oxidative stress and mitochondrial fission.
RND3 attenuates oxidative stress and vascular remodeling in spontaneously hypertensive rat via inhibiting ROCK1 signaling.
Maternal supply of cysteamine alleviates oxidative stress and enhances angiogenesis in porcine placenta.
Ginkgetin Alleviates Inflammation, Oxidative Stress, and Apoptosis Induced by Hypoxia/Reoxygenation in H9C2 Cells via Caspase-3 Dependent Pathway.
Brevilin A Inhibits STAT3 Signaling and Induces ROS-Dependent Apoptosis, Mitochondrial Stress and Endoplasmic Reticulum Stress in MCF-7 Breast Cancer Cells.
Targeting Epstein-Barr virus oncoprotein LMP1-mediated high oxidative stress suppresses EBV lytic reactivation and sensitizes tumors to radiation therapy.
Magnesium isoglycyrrhizinate alleviates fructose-induced liver oxidative stress and inflammatory injury through suppressing NOXs.
Protective effect of Berberine on reproductive function and spermatogenesis in diabetic rats via inhibition of ROS/JAK2/NFκB pathway.
MiR155-5p Inhibits Cell Migration and Oxidative Stress in Vascular Smooth Muscle Cells of Spontaneously Hypertensive Rats.
Cathelicidin Modulates Vascular Smooth Muscle Cell Phenotypic Switching through ROS/IL-6 Pathway.
p47phox deficiency impairs platelet function and protects mice against arterial and venous thrombosis.
The Role of Testosterone in Amplifying the Effect of a Phosphodiesterase Type 5 Inhibitor After Pelvic Irradiation.
Increased Blood Pressure Causes Lymphatic Endothelial Dysfunction via Oxidative Stress in Spontaneously Hypertensive Rats.
BCL6 Attenuates Proliferation and Oxidative Stress of Vascular Smooth Muscle Cells in Hypertension.
Propofol Alleviates DNA Damage Induced by Oxygen Glucose Deprivation and Reperfusion via FoxO1 Nuclear Translocation in H9c2 Cells.
Protective Effects of 18β-Glycyrrhetinic Acid on Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats.
Human tissue kallikrein-1 protects against the development of erectile dysfunction in a rat model of hyperhomocysteinemia.
Astragaloside IV alleviates doxorubicin induced cardiomyopathy by inhibiting NADPH oxidase derived oxidative stress.
Allicin ameliorates obesity comorbid depressive-like behaviors: involvement of the oxidative stress, mitochondrial function, autophagy, insulin resistance and NOX/Nrf2 imbalance in mice.
(Pro)renin Receptor is Involved in Myocardial Damage in Alcoholic Cardiomyopathy.
MicroRNA-24 inhibits the oxidative stress induced by vascular injury by activating the Nrf2/Ho-1 signaling pathway.
Exogenous hydrogen sulfide protects against high glucose-induced apoptosis and oxidative stress by inhibiting the STAT3/HIF-1α pathway in H9c2 cardiomyocytes.
Role of JAK2 in the Pathogenesis of Diabetic Erectile Dysfunction and an Intervention With Berberine.
Chronic fetal hypoxia disrupts the peri-conceptual environment in next-generation adult female rats.
Growth differentiation factor 11 is involved in isoproterenol‑induced heart failure.
Oxidative and endoplasmic reticulum stresses are involved in palmitic acid-induced H9c2 cell apoptosis.
Chronic gestational hypoxia accelerates ovarian aging and lowers ovarian reserve in next-generation adult rats.
Testosterone preserves endothelial function through regulation of S1P1/Akt/FOXO3a signalling pathway in the rat corpus cavernosum.
Sensory plasticity of carotid body is correlated with oxidative stress in paraventricular nucleus during chronic intermittent hypoxia.
Inhibiting inflammation and modulating oxidative stress in oxalate-induced nephrolithiasis with the Nrf2 activator dimethyl fumarate.
Calcium Release from Endoplasmic Reticulum Involves Calmodulin-Mediated NADPH Oxidase-Derived Reactive Oxygen Species Production in Endothelial Cells.
Downregulated Expression of Solute Carrier Family 26 Member 6 in NRK-52E Cells Attenuates Oxalate-Induced Intracellular Oxidative Stress.
Losartan Ameliorates Calcium Oxalate-Induced Elevation of Stone-Related Proteins in Renal Tubular Cells by Inhibiting NADPH Oxidase and Oxidative Stress.
Notch inhibitor can attenuate apparent diffusion coefficient and improve neurological function through downregulating NOX2-ROS in severe traumatic brain injury.
BRG1 regulates NOX gene transcription in endothelial cells and contributes to cardiac ischemia-reperfusion injury.
Myocardin-related transcription factor A (MRTF-A) contributes to acute kidney injury by regulating macrophage ROS production.
Lipoxin A4 improves erectile dysfunction in rats with type I diabetes by inhibiting oxidative stress and corporal fibrosis.
Argirein alleviates vascular endothelial insulin resistance through suppressing the activation of Nox4-dependent O(2)(-) production in diabetic rats.
Megakaryocytic Leukemia 1 Bridges Epigenetic Activation of NADPH Oxidase in Macrophages to Cardiac Ischemia-Reperfusion Injury.
MitoTEMPO Prevents Oxalate Induced Injury in NRK-52E Cells via Inhibiting Mitochondrial Dysfunction and Modulating Oxidative Stress.
Berberine ameliorates fatty acid-induced oxidative stress in human hepatoma cells.
Therapeutic effect of human ghrelin and growth hormone: Attenuation of immunosuppression in septic aged rats.
Activation of ATP-sensitive potassium channel by iptakalim normalizes stress-induced HPA axis disorder and depressive behaviour by alleviating inflammation and oxidative stress in mouse hypothalamus.
Nitro-oleic acid ameliorates oxygen and glucose deprivation/re-oxygenation triggered oxidative stress in renal tubular cells via activation of Nrf2 and suppression of NADPH oxidase.
Poor maternal nutrition and accelerated postnatal growth induces an accelerated aging phenotype and oxidative stress in skeletal muscle of male rats.
Chlorogenic acid protects against liver fibrosis in vivo and in vitro through inhibition of oxidative stress.
PKCα promotes generation of reactive oxygen species via DUOX2 in hepatocellular carcinoma.
The phosphodiesterase-5 inhibitor vardenafil reduces oxidative stress while reversing pulmonary arterial hypertension.
TIPE2, a novel regulator of immunity, protects against experimental stroke.
Cao H, Chen L, Zeng Z, Wu X, Lei Y, Jia W, Yue G, Yi B, Li YJ, Shi Y
PeerJ 2024;12:e16744
PeerJ 2024;12:e16744
NOX2 and NOX4 expression in monocytes and macrophages-extracellular vesicles in signalling and therapeutics.
Rathi D, Rossi C, Pospíšil P, Ramalingam Manoharan R, Talarico L, Magnani A, Prasad A
Frontiers in cell and developmental biology 2024;12:1342227
Frontiers in cell and developmental biology 2024;12:1342227
Inhibition of MST1 ameliorates neuronal apoptosis via GSK3β/β-TrCP/NRF2 pathway in spinal cord injury accompanied by diabetes.
Huang W, Wu D, Cai C, Yao H, Tian Z, Yang Y, Pang M, Rong L, Liu B
Redox biology 2024 May;71:103104
Redox biology 2024 May;71:103104
Food therapy of scutellarein ameliorates pirarubicin‑induced cardiotoxicity in rats by inhibiting apoptosis and ferroptosis through regulation of NOX2‑induced oxidative stress.
Lan Y, Tian F, Tang H, Pu P, He Q, Duan L
Molecular medicine reports 2024 May;29(5)
Molecular medicine reports 2024 May;29(5)
Caffeic acid phenethyl ester inhibits neuro-inflammation and oxidative stress following spinal cord injury by mitigating mitochondrial dysfunction via the SIRT1/PGC1α/DRP1 signaling pathway.
Zhang Y, Deng Q, Hong H, Qian Z, Wan B, Xia M
Journal of translational medicine 2024 Mar 25;22(1):304
Journal of translational medicine 2024 Mar 25;22(1):304
FGF21 Inhibits Hypoxia/Reoxygenation-induced Renal Tubular Epithelial Cell Injury by Regulating the PPARγ/NF-κB Signaling Pathway.
Li R, Liu X
Cell biochemistry and biophysics 2024 Jun;82(2):909-918
Cell biochemistry and biophysics 2024 Jun;82(2):909-918
Intracellular and extracellular Cyclophilin a promote cardiac fibrosis through TGF-β signaling in response to angiotensin Ⅱ.
Cao M, Zhao Q, Xia H, Lyu S, Luo J, Fu K, Chen R, Yuan W
Biochemical pharmacology 2024 Jul;225:116271
Biochemical pharmacology 2024 Jul;225:116271
Nicotinamide mononucleotide attenuates airway epithelial barrier dysfunction via inhibiting SIRT3 SUMOylation in asthma.
Liang J, Zhou C, Zhang C, Liang S, Zhou Z, Zhou Z, Wu C, Zhao H, Meng X, Zou F, Yu C, Cai S
International immunopharmacology 2024 Jan 25;127:111328
International immunopharmacology 2024 Jan 25;127:111328
The antihypertensive effect of Alizarin is achieved by activating VEGFR2/eNOS pathway, attenuating oxidative stress-induced mitochondrial damage and premature senescence.
Qian YW, Guo YQ, Li YL, Wang Y, Guo S, Niu QQ, Zhu ML, Li P
Life sciences 2024 Aug 15;351:122862
Life sciences 2024 Aug 15;351:122862
Mitochondrial complex I activity in microglia sustains neuroinflammation.
Peruzzotti-Jametti L, Willis CM, Krzak G, Hamel R, Pirvan L, Ionescu RB, Reisz JA, Prag HA, Garcia-Segura ME, Wu V, Xiang Y, Barlas B, Casey AM, van den Bosch AMR, Nicaise AM, Roth L, Bates GR, Huang H, Prasad P, Vincent AE, Frezza C, Viscomi C, Balmus G, Takats Z, Marioni JC, D'Alessandro A, Murphy MP, Mohorianu I, Pluchino S
Nature 2024 Apr;628(8006):195-203
Nature 2024 Apr;628(8006):195-203
CYBB-Mediated Ferroptosis Associated with Immunosuppression in Mycobacterium leprae-Infected Monocyte-Derived Macrophages.
Wang Z, Liu T, Wang Z, Mi Z, Zhang Y, Wang C, Sun L, Ma S, Xue X, Liu H, Zhang F
The Journal of investigative dermatology 2024 Apr;144(4):874-887.e2
The Journal of investigative dermatology 2024 Apr;144(4):874-887.e2
GKT137831 in combination with adipose-derived stem cells alleviates high glucose-induced inflammaging and improves diabetic wound healing.
Dong Y, Zhang Y, Li F, Tang B, Lv D, Wang H, Luo S
Journal of leukocyte biology 2024 Apr 29;115(5):882-892
Journal of leukocyte biology 2024 Apr 29;115(5):882-892
Sphingolipid biosynthesis is essential for metabolic rewiring during T(H)17 cell differentiation.
Abimannan T, Parthibane V, Le SH, Vijaykrishna N, Fox SD, Karim B, Kunduri G, Blankenberg D, Andresson T, Bamba T, Acharya U, Acharya JK
Science advances 2024 Apr 26;10(17):eadk1045
Science advances 2024 Apr 26;10(17):eadk1045
Esculin targets TLR4 to protect against LPS-induced septic cardiomyopathy.
Su Z, Gao M, Weng L, Xu T
International immunopharmacology 2024 Apr 20;131:111897
International immunopharmacology 2024 Apr 20;131:111897
Nox2 inhibition reduces trophoblast ferroptosis in preeclampsia via the STAT3/GPX4 pathway.
Xu X, Zhu M, Zu Y, Wang G, Li X, Yan J
Life sciences 2024 Apr 15;343:122555
Life sciences 2024 Apr 15;343:122555
Antigen stasis and airway nitrosative stress in human primary ciliary dyskinesia.
Gaston B, Smith LA, Davis MD, Saunders J, Daniels I, Horani A, Brody SL, Giddings O, Zhao Y, Marozkina N
American journal of physiology. Lung cellular and molecular physiology 2024 Apr 1;326(4):L468-L476
American journal of physiology. Lung cellular and molecular physiology 2024 Apr 1;326(4):L468-L476
Adipocyte-Derived Exosomal NOX4-Mediated Oxidative Damage Induces Premature Placental Senescence in Obese Pregnancy.
Tao Y, Chen W, Xu H, Xu J, Yang H, Luo X, Chen M, He J, Bai Y, Qi H
International journal of nanomedicine 2023;18:4705-4726
International journal of nanomedicine 2023;18:4705-4726
Effects of liraglutide on astrocyte polarization and neuroinflammation in db/db mice: focus on iron overload and oxidative stress.
An JR, Liu JT, Gao XM, Wang QF, Sun GY, Su JN, Zhang C, Yu JX, Yang YF, Shi Y
Frontiers in cellular neuroscience 2023;17:1136070
Frontiers in cellular neuroscience 2023;17:1136070
Identification and validation of immune-associated NETosis subtypes and biomarkers in anti-neutrophil cytoplasmic antibody associated glomerulonephritis.
Tao M, He Y, Li L, Li Y, Liao W, Nie H, Gao P
Frontiers in immunology 2023;14:1177968
Frontiers in immunology 2023;14:1177968
FGL2 deficiency alleviates maternal inflammation-induced blood-brain barrier damage by blocking PI3K/NF-κB mediated endothelial oxidative stress.
Huang L, Zhan D, Xing Y, Yan Y, Li Q, Zhang J, Li S, Ning Q, Zhang C, Luo X
Frontiers in immunology 2023;14:1157027
Frontiers in immunology 2023;14:1157027
Oscillatory shear stress promotes vein graft intimal hyperplasia via NADPH oxidase-related pathways.
Yao G, Li H, Zuo X, Wang C, Xiao Y, Zhao Y, Wang X
Frontiers in surgery 2023;10:1073557
Frontiers in surgery 2023;10:1073557
Pure total flavonoids from citrus alleviate oxidative stress and inflammation in nonalcoholic fatty liver disease by regulating the miR-137-3p/NOXA2/NOX2 pathway.
Yan JB, Nie YM, Xu SM, Zhang S, Chen ZY
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154944
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154944
A Novel NOX Inhibitor Alleviates Parkinson's Disease Pathology in PFF-Injected Mice.
Ofori K, Ghosh A, Verma DK, Wheeler D, Cabrera G, Seo JB, Kim YH
International journal of molecular sciences 2023 Sep 19;24(18)
International journal of molecular sciences 2023 Sep 19;24(18)
Inhibition of AT1R/IP3/IP3R-mediated Ca(2+) release protects against calcium oxalate crystals-induced renal oxidative stress.
Hong SY, Yang YY, Wang SG, Qin BL
Chemico-biological interactions 2023 Sep 1;382:110636
Chemico-biological interactions 2023 Sep 1;382:110636
Niclosamide Inhibits Aortic Valve Interstitial Cell Calcification by Interfering with the GSK-3β/β-Catenin Signaling Pathway.
Adhikari R, Shiwakoti S, Kim E, Choi IJ, Park SH, Ko JY, Chang K, Oak MH
Biomolecules & therapeutics 2023 Sep 1;31(5):515-525
Biomolecules & therapeutics 2023 Sep 1;31(5):515-525
Transient receptor potential vanilloid 4 (TRPV4) in neutrophils enhances myocardial ischemia/reperfusion injury.
Wu Y, Lu K, Lu Y, Liao J, Zhang S, Yang S, Zhao N, Dong Q, Chen L, Wu Q, Du Y
Journal of leukocyte biology 2023 Sep 1;114(3):266-279
Journal of leukocyte biology 2023 Sep 1;114(3):266-279
Glucocorticoid-induced activation of NOX/ROS/NF-κB signaling in MSCs contributes to the development of GONFH.
Xu H, Zeng Q, Zou K, Huang H, Chen J, Wang P, Yuan W, Xiao L, Tong P, Jin H
Apoptosis : an international journal on programmed cell death 2023 Oct;28(9-10):1332-1345
Apoptosis : an international journal on programmed cell death 2023 Oct;28(9-10):1332-1345
Intermittent fasting alleviates type 1 diabetes-induced cognitive dysfunction by improving the frontal cortical metabolic disorder.
Xiong F, Jiang K, Wu Y, Lou C, Ding C, Zhang W, Zhang X, Li C, Zheng H, Gao H
Biochimica et biophysica acta. Molecular basis of disease 2023 Oct;1869(7):166725
Biochimica et biophysica acta. Molecular basis of disease 2023 Oct;1869(7):166725
The novel peptide athycaltide-1 attenuates Ang II-induced pathological myocardial hypertrophy by reducing ROS and inhibiting the activation of CaMKII and ERK1/2.
Zheng X, Su F, Lei M, Li J, Zhang C, Zhang Y, Wei M, Li W, Chen S, Liu Y, Gao Q, Hao L
European journal of pharmacology 2023 Oct 15;957:175969
European journal of pharmacology 2023 Oct 15;957:175969
Colchicine protects against the development of experimental abdominal aortic aneurysm.
Zhao Y, Shen QR, Chen YX, Shi Y, Wu WB, Li Q, Li DJ, Shen FM, Fu H
Clinical science (London, England : 1979) 2023 Oct 11;137(19):1533-1545
Clinical science (London, England : 1979) 2023 Oct 11;137(19):1533-1545
Short-chain acyl-CoA dehydrogenase is a potential target for the treatment of vascular remodelling.
Zhong X, Li Z, Xu Q, Peng H, Su Y, Le K, Shu Z, Liao Y, Ma Z, Pan X, Xu S, Zhou S
Journal of hypertension 2023 May 1;41(5):775-793
Journal of hypertension 2023 May 1;41(5):775-793
Electroacupuncture alleviates early brain injury via modulating microglia polarization and suppressing neuroinflammation in a rat model of subarachnoid hemorrhage.
Wang Y, Yang X, Cao Y, Li X, Xu R, Yan J, Guo Z, Sun S, Sun X, Wu Y
Heliyon 2023 Mar;9(3):e14475
Heliyon 2023 Mar;9(3):e14475
Lnc-17Rik promotes the immunosuppressive function of Myeloid-Derived suppressive cells in esophageal cancer.
Wen J, Xuan B, Gao Y, Liu Y, Wang L, He L, Meng X, Zhou T, Tao Y, Guo K, Wang Y
Cellular immunology 2023 Mar;385:104676
Cellular immunology 2023 Mar;385:104676
Dioscin ameliorates silica-aggravated systemic lupus erythematosus via suppressing apoptosis and improving LC3-associated phagocytosis in MRL/lpr mice.
Zhang P, Lei X, Ou L, Cheng Y, Miao Q, Li C, Chen Y
International immunopharmacology 2023 Mar;116:109814
International immunopharmacology 2023 Mar;116:109814
Capsaicin inhibits aortic valvular interstitial cell calcification via the redox-sensitive NFκB/AKT/ERK1/2 pathway.
Adhikari R, Jung J, Shiwakoti S, Park EY, Kim HJ, Ko JY, You J, Lee M, Oak MH
Biochemical pharmacology 2023 Jun;212:115530
Biochemical pharmacology 2023 Jun;212:115530
Synergistic effect of elevated glucose levels with SARS-CoV-2 spike protein induced NOX-dependent ROS production in endothelial cells.
Zhang J, He L, Huang R, Alvarez JF, Yang DH, Sun Q, Wang F, Peng Z, Jiang N, Su L
Molecular biology reports 2023 Jul;50(7):6039-6047
Molecular biology reports 2023 Jul;50(7):6039-6047
The pro-inflammatory signature of lipopolysaccharide in spontaneous contracting embryoid bodies differentiated from mouse embryonic stem cells.
Scharmacher J, Wartenberg M, Sauer H
Journal of cellular and molecular medicine 2023 Jul;27(14):2045-2058
Journal of cellular and molecular medicine 2023 Jul;27(14):2045-2058
Contemporary Antiretroviral Therapy Dysregulates Iron Transport and Augments Mitochondrial Dysfunction in HIV-Infected Human Microglia and Neural-Lineage Cells.
Kaur H, Minchella P, Alvarez-Carbonell D, Purandare N, Nagampalli VK, Blankenberg D, Hulgan T, Gerschenson M, Karn J, Aras S, Kallianpur AR
International journal of molecular sciences 2023 Jul 31;24(15)
International journal of molecular sciences 2023 Jul 31;24(15)
Dysregulated B7H4/JAK2/STAT3 Pathway Involves in Hypertriglyceridemia Acute Pancreatitis and Is Attenuated by Baicalin.
Yang J, Han F, Wu G, Dong Y, Su H, Xu J, Li J
Digestive diseases and sciences 2023 Feb;68(2):478-486
Digestive diseases and sciences 2023 Feb;68(2):478-486
Stromal Vascular Fraction Restores Vasodilatory Function by Reducing Oxidative Stress in Aging-Induced Coronary Microvascular Disease.
Tracy EP, Dukes M, Rowe G, Beare JE, Nair R, LeBlanc AJ
Antioxidants & redox signaling 2023 Feb;38(4-6):261-281
Antioxidants & redox signaling 2023 Feb;38(4-6):261-281
Saxagliptin alleviates erectile dysfunction through increasing stromal cell-derived factor-1 in diabetes mellitus.
Sun T, Xu W, Wang J, Wang T, Wang S, Liu K, Liu J
Andrology 2023 Feb;11(2):295-306
Andrology 2023 Feb;11(2):295-306
Acid sphingomyelinase promotes diabetic cardiomyopathy via NADPH oxidase 4 mediated apoptosis.
Liu R, Duan T, Yu L, Tang Y, Liu S, Wang C, Fang WJ
Cardiovascular diabetology 2023 Feb 2;22(1):25
Cardiovascular diabetology 2023 Feb 2;22(1):25
Adrenomedullin Improves Hypertension and Vascular Remodeling partly through the Receptor-Mediated AMPK Pathway in Rats with Obesity-Related Hypertension.
Wang HY, Wang FZ, Chang R, Wang Q, Liu SY, Cheng ZX, Gao Q, Zhou H, Zhou YB
International journal of molecular sciences 2023 Feb 15;24(4)
International journal of molecular sciences 2023 Feb 15;24(4)
Exosomal RBP4 potentiated hepatic lipid accumulation and inflammation in high-fat-diet-fed mice by promoting M1 polarization of Kupffer cells.
Yao JM, Ying HZ, Zhang HH, Qiu FS, Wu JQ, Yu CH
Free radical biology & medicine 2023 Feb 1;195:58-73
Free radical biology & medicine 2023 Feb 1;195:58-73
Apolipoprotein C-III itself stimulates the Syk/cPLA2-induced inflammasome activation of macrophage to boost anti-tumor activity of CD8(+) T cell.
Hu X, Ding S, Lu G, Lin Z, Liao L, Xiao W, Ding Y, Zhang Y, Wang Z, Gong W, Jia X
Cancer immunology, immunotherapy : CII 2023 Dec;72(12):4123-4144
Cancer immunology, immunotherapy : CII 2023 Dec;72(12):4123-4144
Nogo-B mediates endothelial oxidative stress and inflammation to promote coronary atherosclerosis in pressure-overloaded mouse hearts.
Zhang Y, Li JJ, Xu R, Wang XP, Zhao XY, Fang Y, Chen YP, Ma S, Di XH, Wu W, She G, Pang ZD, Wang YD, Zhang X, Xie W, Deng XL, Du XJ, Zhang Y
Redox biology 2023 Dec;68:102944
Redox biology 2023 Dec;68:102944
Comprehensive analysis and identification of prognostic biomarkers and immunotherapeutic targets in the NADPH oxidase family (and its regulatory subunits) in pancreatic ductal adenocarcinoma.
Guo R, Zheng P, Zhu S, Zeng Z, Li Z, Yang Y
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2023 Dec;25(12):3460-3470
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2023 Dec;25(12):3460-3470
BMP4 inhibits corneal neovascularization by interfering with tip cells in angiogenesis.
Nan W, He Y, Shen S, Wu M, Wang S, Zhang Y
Experimental eye research 2023 Dec;237:109680
Experimental eye research 2023 Dec;237:109680
Fibroblast growth factor 21 protects the liver from apoptosis in a type 1 diabetes mouse model via regulating L-lactate homeostasis.
Yan J, Xie J, Xu S, Guo Y, Ji K, Li C, Gao H, Zhao L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115737
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115737
Purinergic receptor P2X7 activates NOX2/JNK signaling to participate in granulosa cell inflammation and apoptosis in polycystic ovary syndrome.
Shen C, Jiang Y, Lin J, He Y, Liu Y, Fang D
Journal of bioenergetics and biomembranes 2023 Aug;55(4):313-322
Journal of bioenergetics and biomembranes 2023 Aug;55(4):313-322
Angiotensin II Increases Oxidative Stress and Inflammation in Female, But Not Male, Endothelial Cells.
Weber CM, Harris MN, Zic SM, Sangha GS, Arnold NS, Dluzen DF, Clyne AM
Cellular and molecular bioengineering 2023 Apr;16(2):127-141
Cellular and molecular bioengineering 2023 Apr;16(2):127-141
SGLT2 inhibition ameliorates nano plastics-induced premature endothelial senescence and dysfunction.
Dhakal B, Shiwakoti S, Park EY, Kang KW, Schini-Kerth VB, Park SH, Ji HY, Park JS, Ko JY, Oak MH
Scientific reports 2023 Apr 17;13(1):6256
Scientific reports 2023 Apr 17;13(1):6256
Aerobic Exercise Training Improves Renal Injury in Spontaneously Hypertensive Rats by Increasing Renalase Expression in Medulla.
Luo M, Cao S, Lv D, He L, He Z, Li L, Li Y, Luo S, Chang Q
Frontiers in cardiovascular medicine 2022;9:922705
Frontiers in cardiovascular medicine 2022;9:922705
Lonicera caerulea Berry Polyphenols Extract Alleviates Exercise Fatigue in Mice by Reducing Oxidative Stress, Inflammation, Skeletal Muscle Cell Apoptosis, and by Increasing Cell Proliferation.
Liu S, Meng F, Zhang D, Shi D, Zhou J, Guo S, Chang X
Frontiers in nutrition 2022;9:853225
Frontiers in nutrition 2022;9:853225
Recurrent Hypoglycemia Impaired Vascular Function in Advanced T2DM Rats by Inducing Pyroptosis.
Luo M, Hu Y, Lv D, Xie L, Yang S, Zuo D, Xue Y, He A
Oxidative medicine and cellular longevity 2022;2022:7812407
Oxidative medicine and cellular longevity 2022;2022:7812407
Schisandrin B Diet Inhibits Oxidative Stress to Reduce Ferroptosis and Lipid Peroxidation to Prevent Pirarubicin-Induced Hepatotoxicity.
Shi H, Yan Y, Yang H, Pu P, Tang H
BioMed research international 2022;2022:5623555
BioMed research international 2022;2022:5623555
Angiotensin II Induces Cardiac Edema and Hypertrophic Remodeling through Lymphatic-Dependent Mechanisms.
Bai J, Yin L, Yu WJ, Zhang YL, Lin QY, Li HH
Oxidative medicine and cellular longevity 2022;2022:5044046
Oxidative medicine and cellular longevity 2022;2022:5044046
Soluble Epoxide Hydrolase Inhibition Protected against Diabetic Cardiomyopathy through Inducing Autophagy and Reducing Apoptosis Relying on Nrf2 Upregulation and Transcription Activation.
Fang Q, Liu X, Ding J, Zhang Z, Chen G, Du T, Wang Y, Xu R
Oxidative medicine and cellular longevity 2022;2022:3773415
Oxidative medicine and cellular longevity 2022;2022:3773415
Change in Oxidative Stress and Mitochondrial Dynamics in Response to Elevated Cold-Inducible RNA-Binding Protein in Cardiac Surgery-Associated Acute Kidney Injury.
Zheng X, Fan Y, Li J, Ma T, Li Y, Wang Q, Yan Y, Liu W
Oxidative medicine and cellular longevity 2022;2022:3576892
Oxidative medicine and cellular longevity 2022;2022:3576892
Pyrrosia petiolosa Extract Ameliorates Ethylene Glycol-Induced Urolithiasis in Rats by Inhibiting Oxidative Stress and Inflammatory Response.
Zhou F, Wang X
Disease markers 2022;2022:1913067
Disease markers 2022;2022:1913067
Rosmarinic Acid Ameliorates Pulmonary Ischemia/Reperfusion Injury by Activating the PI3K/Akt Signaling Pathway.
Luo W, Tao Y, Chen S, Luo H, Li X, Qu S, Chen K, Zeng C
Frontiers in pharmacology 2022;13:860944
Frontiers in pharmacology 2022;13:860944
A Novel Compound, Tanshinol Borneol Ester, Ameliorates Pressure Overload-Induced Cardiac Hypertrophy by Inhibiting Oxidative Stress via the mTOR/β-TrCP/NRF2 Pathway.
Han D, Wang F, Wang B, Qiao Z, Cui X, Zhang Y, Jiang Q, Liu M, Shangguan J, Zheng X, Bai Y, Du C, Shen D
Frontiers in pharmacology 2022;13:830763
Frontiers in pharmacology 2022;13:830763
Administration of USP7 inhibitor P22077 inhibited cardiac hypertrophy and remodeling in Ang II-induced hypertensive mice.
Gu YH, Ren KW, Wang Y, Wang SH, Yu XH, Xu LW, Li HH, Bi HL
Frontiers in pharmacology 2022;13:1021361
Frontiers in pharmacology 2022;13:1021361
A dual Keap1 and p47(phox) inhibitor Ginsenoside Rb1 ameliorates high glucose/ox-LDL-induced endothelial cell injury and atherosclerosis.
Wang ZC, Niu KM, Wu YJ, Du KR, Qi LW, Zhou YB, Sun HJ
Cell death & disease 2022 Sep 26;13(9):824
Cell death & disease 2022 Sep 26;13(9):824
Combination Treatment with Hydroxytyrosol and Vitamin E Improves NAFLD-Related Fibrosis.
Panera N, Braghini MR, Crudele A, Smeriglio A, Bianchi M, Condorelli AG, Nobili R, Conti LA, De Stefanis C, Lioci G, Gurrado F, Comparcola D, Mosca A, Sartorelli MR, Scoppola V, Svegliati-Baroni G, Trombetta D, Alisi A
Nutrients 2022 Sep 14;14(18)
Nutrients 2022 Sep 14;14(18)
Edaravone dexborneol protects cerebral ischemia reperfusion injury through activating Nrf2/HO-1 signaling pathway in mice.
Xu L, Gao Y, Hu M, Dong Y, Xu J, Zhang J, Lv P
Fundamental & clinical pharmacology 2022 Oct;36(5):790-800
Fundamental & clinical pharmacology 2022 Oct;36(5):790-800
Inhibition of Hypoxia-Inducible Factor Prolyl-Hydroxylase Modulates Platelet Function.
Gu W, Qi J, Zhang S, Ding Y, Qiao J, Han Y
Thrombosis and haemostasis 2022 Oct;122(10):1693-1705
Thrombosis and haemostasis 2022 Oct;122(10):1693-1705
Suramin enhances chondrogenic properties by regulating the p67(phox)/PI3K/AKT/SOX9 signalling pathway.
Liu ZM, Shen PC, Lu CC, Chou SH, Tien YC
Bone & joint research 2022 Oct;11(10):723-738
Bone & joint research 2022 Oct;11(10):723-738
Mycobacterium tuberculosis Utilizes Host Histamine Receptor H1 to Modulate Reactive Oxygen Species Production and Phagosome Maturation via the p38MAPK-NOX2 Axis.
Mo S, Guo J, Ye T, Zhang X, Zeng J, Xu Y, Peng B, Dai Y, Xiao W, Zhang P, Deng G, Xu D, Long X, Cai Y, Chen X
mBio 2022 Oct 26;13(5):e0200422
mBio 2022 Oct 26;13(5):e0200422
Identification of a necroptosis-related prognostic gene signature associated with tumor immune microenvironment in cervical carcinoma and experimental verification.
Sun K, Huang C, Li JZ, Luo ZX
World journal of surgical oncology 2022 Oct 17;20(1):342
World journal of surgical oncology 2022 Oct 17;20(1):342
Gut microbiome dysbiosis contributes to abdominal aortic aneurysm by promoting neutrophil extracellular trap formation.
Tian Z, Zhang Y, Zheng Z, Zhang M, Zhang T, Jin J, Zhang X, Yao G, Kong D, Zhang C, Wang Z, Zhang Q
Cell host & microbe 2022 Oct 12;30(10):1450-1463.e8
Cell host & microbe 2022 Oct 12;30(10):1450-1463.e8
The Clostridium Metabolite P-Cresol Sulfate Relieves Inflammation of Primary Biliary Cholangitis by Regulating Kupffer Cells.
Fu HY, Xu JM, Ai X, Dang FT, Tan X, Yu HY, Feng J, Yang WX, Ma HT, Tu RF, Gupta AK, Manandhar LK, Bao WM, Tang YM
Cells 2022 Nov 26;11(23)
Cells 2022 Nov 26;11(23)
Lipopolysaccharide induces placental mitochondrial dysfunction in murine and human systems by reducing MNRR1 levels via a TLR4-independent pathway.
Purandare N, Kunji Y, Xi Y, Romero R, Gomez-Lopez N, Fribley A, Grossman LI, Aras S
iScience 2022 Nov 18;25(11):105342
iScience 2022 Nov 18;25(11):105342
Graphene oxide leads to mitochondrial-dependent apoptosis by activating ROS-p53-mPTP pathway in intestinal cells.
Feng W, Wang J, Li B, Liu Y, Xu D, Cheng K, Zhuang J
The international journal of biochemistry & cell biology 2022 May;146:106206
The international journal of biochemistry & cell biology 2022 May;146:106206
Impact of Selective Renal Afferent Denervation on Oxidative Stress and Vascular Remodeling in Spontaneously Hypertensive Rats.
Wu LL, Zhang Y, Li XZ, Du XL, Gao Y, Wang JX, Wang XL, Chen Q, Li YH, Zhu GQ, Tan X
Antioxidants (Basel, Switzerland) 2022 May 20;11(5)
Antioxidants (Basel, Switzerland) 2022 May 20;11(5)
Pu-erh Tea Restored Circadian Rhythm Disruption by Regulating Tryptophan Metabolism.
Hu S, Luo L, Bian X, Liu RH, Zhao S, Chen Y, Sun K, Jiang J, Liu Z, Zeng L
Journal of agricultural and food chemistry 2022 May 11;70(18):5610-5623
Journal of agricultural and food chemistry 2022 May 11;70(18):5610-5623
Prednisone Ameliorates Atrial Inflammation and Fibrosis in Atrial Tachypacing Dogs.
Zhang H, Lai Y, Zhou H, Zou L, Xu Y, Yin Y
International heart journal 2022 Mar 30;63(2):347-355
International heart journal 2022 Mar 30;63(2):347-355
Effects of polystyrene nanoplastics on endothelium senescence and its underlying mechanism.
Shiwakoti S, Ko JY, Gong D, Dhakal B, Lee JH, Adhikari R, Gwak Y, Park SH, Jun Choi I, Schini-Kerth VB, Kang KW, Oak MH
Environment international 2022 Jun;164:107248
Environment international 2022 Jun;164:107248
Disruption of mitochondrial redox homeostasis as a mechanism of antimony-induced reactive oxygen species and cytotoxicity.
Su L, Fang W, Zhao X, Zhu L, Gao L, Chen G
Ecotoxicology and environmental safety 2022 Jun 1;237:113519
Ecotoxicology and environmental safety 2022 Jun 1;237:113519
In utero hypoxia attenuated acetylcholine-mediated vasodilatation via CHRM3/p-NOS3 in fetal sheep MCA: role of ROS/ERK1/2.
He Y, Su H, Li N, Zhang Y, Zhang P, Zhang Y, Ye Y, Zhang Y, Tang J, Xu Z
Hypertension research : official journal of the Japanese Society of Hypertension 2022 Jul;45(7):1168-1182
Hypertension research : official journal of the Japanese Society of Hypertension 2022 Jul;45(7):1168-1182
Accumulation of advanced oxidation protein products contributes to age-related impairment of gap junction intercellular communication in osteocytes of male mice.
Tu C, Lai S, Huang Z, Cai G, Zhao K, Gao J, Wu Z, Zhong Z
Bone & joint research 2022 Jul;11(7):413-425
Bone & joint research 2022 Jul;11(7):413-425
Role of Nox4 in High Calcium-Induced Renal Oxidative Stress Damage and Crystal Deposition.
Xun Y, Zhou P, Yang Y, Li C, Zhang J, Hu H, Qin B, Zhang Z, Wang Q, Lu Y, Wang S
Antioxidants & redox signaling 2022 Jan;36(1-3):15-38
Antioxidants & redox signaling 2022 Jan;36(1-3):15-38
Reducing oxidative stress may be important for treating pirarubicin-induced cardiotoxicity with schisandrin B.
Tang H, Zhao J, Feng R, Pu P, Wen L
Experimental and therapeutic medicine 2022 Jan;23(1):68
Experimental and therapeutic medicine 2022 Jan;23(1):68
mTORC1 activation induced proximal tubular damage via the pentose phosphate pathway in lupus nephritis.
Mao Z, Tan Y, Tao J, Li L, Yu F, Zhao M
Free radical biology & medicine 2022 Aug 20;189:91-101
Free radical biology & medicine 2022 Aug 20;189:91-101
Chronic Sigma 1 receptor activation alleviates right ventricular dysfunction secondary to pulmonary arterial hypertension.
Sun Y, Wan W, Zhao X, Han X, Ye T, Chen X, Ran Q, Wang X, Liu X, Qu C, Shi S, Zhang C, Yang B
Bioengineered 2022 Apr;13(4):10843-10856
Bioengineered 2022 Apr;13(4):10843-10856
Honokiol improves endothelial function in type 2 diabetic rats via alleviating oxidative stress and insulin resistance.
He A, Yu H, Hu Y, Chen H, Li X, Shen J, Zhuang R, Chen Y, Sasmita BR, Luo M, Lv D
Biochemical and biophysical research communications 2022 Apr 16;600:109-116
Biochemical and biophysical research communications 2022 Apr 16;600:109-116
A Novel NOX Inhibitor Treatment Attenuates Parkinson's Disease-Related Pathology in Mouse Models.
Ghosh AA, Verma DK, Cabrera G, Ofori K, Hernandez-Quijada K, Kim JK, Chung JH, Moore M, Moon SH, Seo JB, Kim YH
International journal of molecular sciences 2022 Apr 12;23(8)
International journal of molecular sciences 2022 Apr 12;23(8)
Electronic cigarette exposure causes vascular endothelial dysfunction due to NADPH oxidase activation and eNOS uncoupling.
El-Mahdy MA, Ewees MG, Eid MS, Mahgoup EM, Khaleel SA, Zweier JL
American journal of physiology. Heart and circulatory physiology 2022 Apr 1;322(4):H549-H567
American journal of physiology. Heart and circulatory physiology 2022 Apr 1;322(4):H549-H567
Crocin Improves Endothelial Mitochondrial Dysfunction via GPx1/ROS/KCa3.1 Signal Axis in Diabetes.
Li X, Liu Y, Cao A, Li C, Wang L, Wu Q, Li X, Lv X, Zhu J, Chun H, Laba C, Du X, Zhang Y, Yang H
Frontiers in cell and developmental biology 2021;9:651434
Frontiers in cell and developmental biology 2021;9:651434
Human Tissue Kallikrein 1 Is Downregulated in Elderly Human Prostates and Possesses Potential In Vitro Antioxidative and Antifibrotic Effects in Rodent Prostates.
Zhang M, Luo C, Lin D, Cui K, Chen Z, Liu J
Oxidative medicine and cellular longevity 2021;2021:8877540
Oxidative medicine and cellular longevity 2021;2021:8877540
Shenxian-Shengmai Oral Liquid Improves Sinoatrial Node Dysfunction through the PKC/NOX-2 Signaling Pathway.
Zhang H, Hao M, Li L, Chen K, Qi J, Chen W, Cai X, Chen C, Liu Z, Hou P
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5572140
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5572140
Microglia-Derived Exosomes Improve Spinal Cord Functional Recovery after Injury via Inhibiting Oxidative Stress and Promoting the Survival and Function of Endothelia Cells.
Peng W, Wan L, Luo Z, Xie Y, Liu Y, Huang T, Lu H, Hu J
Oxidative medicine and cellular longevity 2021;2021:1695087
Oxidative medicine and cellular longevity 2021;2021:1695087
17β-Estradiol promotes LC3B-associated phagocytosis in trained immunity of female mice against sepsis.
Sun Z, Qu J, Xia X, Pan Y, Liu X, Liang H, Dou H, Hou Y
International journal of biological sciences 2021;17(2):460-474
International journal of biological sciences 2021;17(2):460-474
Iron Oxide Nanoparticles Combined with Cytosine Arabinoside Show Anti-Leukemia Stem Cell Effects on Acute Myeloid Leukemia by Regulating Reactive Oxygen Species.
Dou J, Li L, Guo M, Mei F, Zheng D, Xu H, Xue R, Bao X, Zhao F, Zhang Y
International journal of nanomedicine 2021;16:1231-1244
International journal of nanomedicine 2021;16:1231-1244
Nox2 contributes to reactive oxygen species-induced redox imbalance in cancer-induced bone pain.
Xu BY, Sun J, Chen SP, Wang XM, Chen N, Li DY, Chen G, Mei W, Tian YK, Zhou YQ, Ye DW
American journal of translational research 2021;13(3):1269-1279
American journal of translational research 2021;13(3):1269-1279
Nox2 impairs VEGF-A-induced angiogenesis in placenta via mitochondrial ROS-STAT3 pathway.
Hu C, Wu Z, Huang Z, Hao X, Wang S, Deng J, Yin Y, Tan C
Redox biology 2021 Sep;45:102051
Redox biology 2021 Sep;45:102051
Compound essential oils relieve oxidative stress caused by PM(2) (.5) exposure by inhibiting autophagy through the AMPK/mTOR pathway.
Ren F, Xu X, Xu J, Mei Y, Zhang J, Wang X, Li F
Environmental toxicology 2021 Sep;36(9):1765-1774
Environmental toxicology 2021 Sep;36(9):1765-1774
Effects of different intensities of continuous training on vascular inflammation and oxidative stress in spontaneously hypertensive rats.
Luo M, Cao C, Niebauer J, Yan J, Ma X, Chang Q, Zhang T, Huang X, Liu G
Journal of cellular and molecular medicine 2021 Sep;25(17):8522-8536
Journal of cellular and molecular medicine 2021 Sep;25(17):8522-8536
Aged Ripe Pu-erh Tea Reduced Oxidative Stress-Mediated Inflammation in Dextran Sulfate Sodium-Induced Colitis Mice by Regulating Intestinal Microbes.
Hu S, Li S, Liu Y, Sun K, Luo L, Zeng L
Journal of agricultural and food chemistry 2021 Sep 15;69(36):10592-10605
Journal of agricultural and food chemistry 2021 Sep 15;69(36):10592-10605
Canagliflozin is a potential cardioprotective drug but exerts no significant effects on pirarubicin‑induced cardiotoxicity in rats.
Shi H, Zeng Q, Wei Y, Yang H, Tang H, Wang D, Pu P, Feng R
Molecular medicine reports 2021 Oct;24(4)
Molecular medicine reports 2021 Oct;24(4)
The protective effect of harpagoside on angiotensin II (Ang II)-induced blood-brain barrier leakage in vitro.
Lu YW, Hao RJ, Wei YY, Yu GR
Phytotherapy research : PTR 2021 Nov;35(11):6241-6254
Phytotherapy research : PTR 2021 Nov;35(11):6241-6254
Distinction between 2'- and 3'-Phosphate Isomers of a Fluorescent NADPH Analogue Led to Strong Inhibition of Cancer Cells Migration.
Manuel R, Lima MS, Dilly S, Daunay S, Abbe P, Pramil E, Solier S, Guillaumond F, Tubiana SS, Escargueil A, Pêgas Henriques JA, Ferrand N, Erdelmeier I, Boucher JL, Bertho G, Agranat I, Rocchi S, Sabbah M, Slama Schwok A
Antioxidants (Basel, Switzerland) 2021 May 4;10(5)
Antioxidants (Basel, Switzerland) 2021 May 4;10(5)
Mild hypothermia in rat with acute myocardial ischaemia-reperfusion injury complicating severe sepsis.
Qin Z, Shen S, Qu K, Nie Y, Zhang H
Journal of cellular and molecular medicine 2021 May 31;25(13):6448-54
Journal of cellular and molecular medicine 2021 May 31;25(13):6448-54
Protective effect of recombinant Lactobacillus plantarum against H(2)O(2)-induced oxidative stress in HUVEC cells.
Wang G, Hao M, Liu Q, Jiang Y, Huang H, Yang G, Wang C
Journal of Zhejiang University. Science. B 2021 May 15;22(5):348-365
Journal of Zhejiang University. Science. B 2021 May 15;22(5):348-365
C-C motif ligand 8 promotes atherosclerosis via NADPH oxidase 2/reactive oxygen species-induced endothelial permeability increase.
Xue S, Tang H, Zhao G, Fang C, Shen Y, Yan D, Yuan Y, Fu W, Shi Z, Tang X, Guo D
Free radical biology & medicine 2021 May 1;167:181-192
Free radical biology & medicine 2021 May 1;167:181-192
Sirtuin 1 ameliorates defenestration in hepatic sinusoidal endothelial cells during liver fibrosis via inhibiting stress-induced premature senescence.
Luo X, Bai Y, He S, Sun S, Jiang X, Yang Z, Lu D, Wei P, Liang Y, Peng C, Wang Y, Sheng R, Han S, Li X, Zhang B
Cell proliferation 2021 Mar;54(3):e12991
Cell proliferation 2021 Mar;54(3):e12991
Scoparone alleviates Ang II-induced pathological myocardial hypertrophy in mice by inhibiting oxidative stress.
Lyu L, Chen J, Wang W, Yan T, Lin J, Gao H, Li H, Lv R, Xu F, Fang L, Chen Y
Journal of cellular and molecular medicine 2021 Mar;25(6):3136-3148
Journal of cellular and molecular medicine 2021 Mar;25(6):3136-3148
Hsa_circ_0005915 promotes N,N-dimethylformamide-induced oxidative stress in HL-7702 cells through NRF2/ARE axis.
Liu Z, He Q, Liu Y, Zhang Y, Cui M, Peng H, Wang Y, Chen S, Li D, Chen L, Xiao Y, Chen W, Wang Q
Toxicology 2021 Jun 30;458:152838
Toxicology 2021 Jun 30;458:152838
Protective effect of scorpion venom heat-resistant synthetic peptide against PM(2.5)-induced microglial polarization via TLR4-mediated autophagy activating PI3K/AKT/NF-κB signaling pathway.
Xu X, Xu H, Ren F, Huang L, Xu J, Li F
Journal of neuroimmunology 2021 Jun 15;355:577567
Journal of neuroimmunology 2021 Jun 15;355:577567
Silencing COX-2 blocks PDK1/TRAF4-induced AKT activation to inhibit fibrogenesis during skeletal muscle atrophy.
Chen H, Qian Z, Zhang S, Tang J, Fang L, Jiang F, Ge D, Chang J, Cao J, Yang L, Cao X
Redox biology 2021 Jan;38:101774
Redox biology 2021 Jan;38:101774
Normothermic machine perfusion attenuates hepatic ischaemia-reperfusion injury by inhibiting CIRP-mediated oxidative stress and mitochondrial fission.
Liu W, Fan Y, Ding H, Han D, Yan Y, Wu R, Lv Y, Zheng X
Journal of cellular and molecular medicine 2021 Dec;25(24):11310-11321
Journal of cellular and molecular medicine 2021 Dec;25(24):11310-11321
RND3 attenuates oxidative stress and vascular remodeling in spontaneously hypertensive rat via inhibiting ROCK1 signaling.
Wu N, Zheng F, Li N, Han Y, Xiong XQ, Wang JJ, Chen Q, Li YH, Zhu GQ, Zhou YB
Redox biology 2021 Dec 6;48:102204
Redox biology 2021 Dec 6;48:102204
Maternal supply of cysteamine alleviates oxidative stress and enhances angiogenesis in porcine placenta.
Huang S, Wu Z, Huang Z, Hao X, Zhang L, Hu C, Wei J, Deng J, Tan C
Journal of animal science and biotechnology 2021 Aug 10;12(1):91
Journal of animal science and biotechnology 2021 Aug 10;12(1):91
Ginkgetin Alleviates Inflammation, Oxidative Stress, and Apoptosis Induced by Hypoxia/Reoxygenation in H9C2 Cells via Caspase-3 Dependent Pathway.
Liu X, Bian H, Dou QL, Huang XW, Tao WY, Liu WH, Li N, Zhang WW
BioMed research international 2020;2020:1928410
BioMed research international 2020;2020:1928410
Brevilin A Inhibits STAT3 Signaling and Induces ROS-Dependent Apoptosis, Mitochondrial Stress and Endoplasmic Reticulum Stress in MCF-7 Breast Cancer Cells.
Saleem MZ, Nisar MA, Alshwmi M, Din SRU, Gamallat Y, Khan M, Ma T
OncoTargets and therapy 2020;13:435-450
OncoTargets and therapy 2020;13:435-450
Targeting Epstein-Barr virus oncoprotein LMP1-mediated high oxidative stress suppresses EBV lytic reactivation and sensitizes tumors to radiation therapy.
Hu J, Li Y, Li H, Shi F, Xie L, Zhao L, Tang M, Luo X, Jia W, Fan J, Zhou J, Gao Q, Qiu S, Wu W, Zhang X, Liao W, Bode AM, Cao Y
Theranostics 2020;10(26):11921-11937
Theranostics 2020;10(26):11921-11937
Magnesium isoglycyrrhizinate alleviates fructose-induced liver oxidative stress and inflammatory injury through suppressing NOXs.
Yang YZ, Liu ZH, Wang SC, Zhang XQ, Xu HJ, Yang L, Kong LD
European journal of pharmacology 2020 Sep 15;883:173314
European journal of pharmacology 2020 Sep 15;883:173314
Protective effect of Berberine on reproductive function and spermatogenesis in diabetic rats via inhibition of ROS/JAK2/NFκB pathway.
Song J, Gao X, Tang Z, Li H, Ruan Y, Liu Z, Wang T, Wang S, Liu J, Jiang H
Andrology 2020 May;8(3):793-806
Andrology 2020 May;8(3):793-806
MiR155-5p Inhibits Cell Migration and Oxidative Stress in Vascular Smooth Muscle Cells of Spontaneously Hypertensive Rats.
Wu N, Ye C, Zheng F, Wan GW, Wu LL, Chen Q, Li YH, Kang YM, Zhu GQ
Antioxidants (Basel, Switzerland) 2020 Mar 1;9(3)
Antioxidants (Basel, Switzerland) 2020 Mar 1;9(3)
Cathelicidin Modulates Vascular Smooth Muscle Cell Phenotypic Switching through ROS/IL-6 Pathway.
Dong X, Wu D, Zhang Y, Jia L, Pan X, Sun J, Pan LL
Antioxidants (Basel, Switzerland) 2020 Jun 5;9(6)
Antioxidants (Basel, Switzerland) 2020 Jun 5;9(6)
p47phox deficiency impairs platelet function and protects mice against arterial and venous thrombosis.
Wang X, Zhang S, Ding Y, Tong H, Xu X, Wei G, Chen Y, Ju W, Fu C, Qi K, Li Z, Zeng L, Xu K, Qiao J
Redox biology 2020 Jul;34:101569
Redox biology 2020 Jul;34:101569
The Role of Testosterone in Amplifying the Effect of a Phosphodiesterase Type 5 Inhibitor After Pelvic Irradiation.
Lee DS, Sohn DW
The journal of sexual medicine 2020 Jul;17(7):1268-1279
The journal of sexual medicine 2020 Jul;17(7):1268-1279
Increased Blood Pressure Causes Lymphatic Endothelial Dysfunction via Oxidative Stress in Spontaneously Hypertensive Rats.
Mukohda M, Mizuno R, Ozaki H
Hypertension (Dallas, Tex. : 1979) 2020 Aug;76(2):598-606
Hypertension (Dallas, Tex. : 1979) 2020 Aug;76(2):598-606
BCL6 Attenuates Proliferation and Oxidative Stress of Vascular Smooth Muscle Cells in Hypertension.
Chen D, Zang YH, Qiu Y, Zhang F, Chen AD, Wang JJ, Chen Q, Li YH, Kang YM, Zhu GQ
Oxidative medicine and cellular longevity 2019;2019:5018410
Oxidative medicine and cellular longevity 2019;2019:5018410
Propofol Alleviates DNA Damage Induced by Oxygen Glucose Deprivation and Reperfusion via FoxO1 Nuclear Translocation in H9c2 Cells.
Zhou D, Zhuang J, Wang Y, Zhao D, Zhao L, Zhu S, Pu J, Yin M, Zhang H, Wang Z, Hong J
Frontiers in physiology 2019;10:223
Frontiers in physiology 2019;10:223
Protective Effects of 18β-Glycyrrhetinic Acid on Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats.
Zhang M, Chang Z, Zhao F, Zhang P, Hao YJ, Yan L, Liu N, Wang JL, Bo L, Ma P, Zhou W, Ma X, Xu QB, Zhou R
Frontiers in pharmacology 2019;10:13
Frontiers in pharmacology 2019;10:13
Human tissue kallikrein-1 protects against the development of erectile dysfunction in a rat model of hyperhomocysteinemia.
Cui K, Luan Y, Tang Z, Li CC, Wang T, Wang SG, Chen Z, Liu JH
Asian journal of andrology 2019 Sep-Oct;21(5):508-515
Asian journal of andrology 2019 Sep-Oct;21(5):508-515
Astragaloside IV alleviates doxorubicin induced cardiomyopathy by inhibiting NADPH oxidase derived oxidative stress.
Lin J, Fang L, Li H, Li Z, Lyu L, Wang H, Xiao J
European journal of pharmacology 2019 Sep 15;859:172490
European journal of pharmacology 2019 Sep 15;859:172490
Allicin ameliorates obesity comorbid depressive-like behaviors: involvement of the oxidative stress, mitochondrial function, autophagy, insulin resistance and NOX/Nrf2 imbalance in mice.
Gao W, Wang W, Zhang J, Deng P, Hu J, Yang J, Deng Z
Metabolic brain disease 2019 Oct;34(5):1267-1280
Metabolic brain disease 2019 Oct;34(5):1267-1280
(Pro)renin Receptor is Involved in Myocardial Damage in Alcoholic Cardiomyopathy.
Xiong J, Cao X, Qiao S, Yu S, Li L, Yu Y, Fu C, Jiang F, Dong B, Su Q
Alcoholism, clinical and experimental research 2019 Nov;43(11):2344-2353
Alcoholism, clinical and experimental research 2019 Nov;43(11):2344-2353
MicroRNA-24 inhibits the oxidative stress induced by vascular injury by activating the Nrf2/Ho-1 signaling pathway.
Zhang J, Cai W, Fan Z, Yang C, Wang W, Xiong M, Ma C, Yang J
Atherosclerosis 2019 Nov;290:9-18
Atherosclerosis 2019 Nov;290:9-18
Exogenous hydrogen sulfide protects against high glucose-induced apoptosis and oxidative stress by inhibiting the STAT3/HIF-1α pathway in H9c2 cardiomyocytes.
Li J, Yuan YQ, Zhang L, Zhang H, Zhang SW, Zhang Y, Xuan XX, Wang MJ, Zhang JY
Experimental and therapeutic medicine 2019 Nov;18(5):3948-3958
Experimental and therapeutic medicine 2019 Nov;18(5):3948-3958
Role of JAK2 in the Pathogenesis of Diabetic Erectile Dysfunction and an Intervention With Berberine.
Song J, Tang Z, Li H, Jiang H, Sun T, Lan R, Wang T, Wang S, Ye Z, Liu J
The journal of sexual medicine 2019 Nov;16(11):1708-1720
The journal of sexual medicine 2019 Nov;16(11):1708-1720
Chronic fetal hypoxia disrupts the peri-conceptual environment in next-generation adult female rats.
Aiken CE, Tarry-Adkins JL, Spiroski AM, Nuzzo AM, Ashmore TJ, Rolfo A, Sutherland MJ, Camm EJ, Giussani DA, Ozanne SE
The Journal of physiology 2019 May;597(9):2391-2401
The Journal of physiology 2019 May;597(9):2391-2401
Growth differentiation factor 11 is involved in isoproterenol‑induced heart failure.
Zhang XJ, Tan H, Shi ZF, Li N, Jia Y, Hao Z
Molecular medicine reports 2019 May;19(5):4109-4118
Molecular medicine reports 2019 May;19(5):4109-4118
Oxidative and endoplasmic reticulum stresses are involved in palmitic acid-induced H9c2 cell apoptosis.
Yang L, Guan G, Lei L, Liu J, Cao L, Wang X
Bioscience reports 2019 May 31;39(5)
Bioscience reports 2019 May 31;39(5)
Chronic gestational hypoxia accelerates ovarian aging and lowers ovarian reserve in next-generation adult rats.
Aiken CE, Tarry-Adkins JL, Spiroski AM, Nuzzo AM, Ashmore TJ, Rolfo A, Sutherland MJ, Camm EJ, Giussani DA, Ozanne SE
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jun;33(6):7758-7766
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jun;33(6):7758-7766
Testosterone preserves endothelial function through regulation of S1P1/Akt/FOXO3a signalling pathway in the rat corpus cavernosum.
Cui K, Li R, Liu K, Wang T, Liu J, Rao K
Andrologia 2019 Feb;51(1):e13173
Andrologia 2019 Feb;51(1):e13173
Sensory plasticity of carotid body is correlated with oxidative stress in paraventricular nucleus during chronic intermittent hypoxia.
Liu P, Zhang HM, Hu K, Zhou XF, Tang S
Journal of cellular physiology 2019 Aug;234(8):13534-13543
Journal of cellular physiology 2019 Aug;234(8):13534-13543
Inhibiting inflammation and modulating oxidative stress in oxalate-induced nephrolithiasis with the Nrf2 activator dimethyl fumarate.
Zhu J, Wang Q, Li C, Lu Y, Hu H, Qin B, Xun Y, Zhu Y, Wu Y, Zhang J, Wang S
Free radical biology & medicine 2019 Apr;134:9-22
Free radical biology & medicine 2019 Apr;134:9-22
Calcium Release from Endoplasmic Reticulum Involves Calmodulin-Mediated NADPH Oxidase-Derived Reactive Oxygen Species Production in Endothelial Cells.
Sakurada R, Odagiri K, Hakamata A, Kamiya C, Wei J, Watanabe H
International journal of molecular sciences 2019 Apr 2;20(7)
International journal of molecular sciences 2019 Apr 2;20(7)
Downregulated Expression of Solute Carrier Family 26 Member 6 in NRK-52E Cells Attenuates Oxalate-Induced Intracellular Oxidative Stress.
Jiang H, Gao X, Gong J, Yang Q, Lan R, Wang T, Liu J, Yin C, Wang S, Liu Z
Oxidative medicine and cellular longevity 2018;2018:1724648
Oxidative medicine and cellular longevity 2018;2018:1724648
Losartan Ameliorates Calcium Oxalate-Induced Elevation of Stone-Related Proteins in Renal Tubular Cells by Inhibiting NADPH Oxidase and Oxidative Stress.
Qin B, Wang Q, Lu Y, Li C, Hu H, Zhang J, Wang Y, Zhu J, Zhu Y, Xun Y, Wang S
Oxidative medicine and cellular longevity 2018;2018:1271864
Oxidative medicine and cellular longevity 2018;2018:1271864
Notch inhibitor can attenuate apparent diffusion coefficient and improve neurological function through downregulating NOX2-ROS in severe traumatic brain injury.
Zhang HM, Chen W, Liu RN, Zhao Y
Drug design, development and therapy 2018;12:3847-3854
Drug design, development and therapy 2018;12:3847-3854
BRG1 regulates NOX gene transcription in endothelial cells and contributes to cardiac ischemia-reperfusion injury.
Li Z, Zhang X, Liu S, Zeng S, Yu L, Yang G, Guo J, Xu Y
Biochimica et biophysica acta. Molecular basis of disease 2018 Oct;1864(10):3477-3486
Biochimica et biophysica acta. Molecular basis of disease 2018 Oct;1864(10):3477-3486
Myocardin-related transcription factor A (MRTF-A) contributes to acute kidney injury by regulating macrophage ROS production.
Liu L, Wu X, Xu H, Yu L, Zhang X, Li L, Jin J, Zhang T, Xu Y
Biochimica et biophysica acta. Molecular basis of disease 2018 Oct;1864(10):3109-3121
Biochimica et biophysica acta. Molecular basis of disease 2018 Oct;1864(10):3109-3121
Lipoxin A4 improves erectile dysfunction in rats with type I diabetes by inhibiting oxidative stress and corporal fibrosis.
Cui K, Tang Z, Li CC, Wang T, Rao K, Wang SG, Liu JH, Chen Z
Asian journal of andrology 2018 Mar-Apr;20(2):166-172
Asian journal of andrology 2018 Mar-Apr;20(2):166-172
Argirein alleviates vascular endothelial insulin resistance through suppressing the activation of Nox4-dependent O(2)(-) production in diabetic rats.
Li Q, Su J, Jin SJ, Wei W, Cong XD, Li XX, Xu M
Free radical biology & medicine 2018 Jun;121:169-179
Free radical biology & medicine 2018 Jun;121:169-179
Megakaryocytic Leukemia 1 Bridges Epigenetic Activation of NADPH Oxidase in Macrophages to Cardiac Ischemia-Reperfusion Injury.
Yu L, Yang G, Zhang X, Wang P, Weng X, Yang Y, Li Z, Fang M, Xu Y, Sun A, Ge J
Circulation 2018 Dec 11;138(24):2820-2836
Circulation 2018 Dec 11;138(24):2820-2836
MitoTEMPO Prevents Oxalate Induced Injury in NRK-52E Cells via Inhibiting Mitochondrial Dysfunction and Modulating Oxidative Stress.
Zhang J, Wang Q, Xu C, Lu Y, Hu H, Qin B, Wang Y, He D, Li C, Yu X, Wang S, Liu J
Oxidative medicine and cellular longevity 2017;2017:7528090
Oxidative medicine and cellular longevity 2017;2017:7528090
Berberine ameliorates fatty acid-induced oxidative stress in human hepatoma cells.
Sun Y, Yuan X, Zhang F, Han Y, Chang X, Xu X, Li Y, Gao X
Scientific reports 2017 Sep 12;7(1):11340
Scientific reports 2017 Sep 12;7(1):11340
Therapeutic effect of human ghrelin and growth hormone: Attenuation of immunosuppression in septic aged rats.
Zhou M, Yang WL, Aziz M, Ma G, Wang P
Biochimica et biophysica acta. Molecular basis of disease 2017 Oct;1863(10 Pt B):2584-2593
Biochimica et biophysica acta. Molecular basis of disease 2017 Oct;1863(10 Pt B):2584-2593
Activation of ATP-sensitive potassium channel by iptakalim normalizes stress-induced HPA axis disorder and depressive behaviour by alleviating inflammation and oxidative stress in mouse hypothalamus.
Zhao XJ, Zhao Z, Yang DD, Cao LL, Zhang L, Ji J, Gu J, Huang JY, Sun XL
Brain research bulletin 2017 Apr;130:146-155
Brain research bulletin 2017 Apr;130:146-155
Nitro-oleic acid ameliorates oxygen and glucose deprivation/re-oxygenation triggered oxidative stress in renal tubular cells via activation of Nrf2 and suppression of NADPH oxidase.
Nie H, Xue X, Liu G, Guan G, Liu H, Sun L, Zhao L, Wang X, Chen Z
Free radical research 2016;50(11):1200-1213
Free radical research 2016;50(11):1200-1213
Poor maternal nutrition and accelerated postnatal growth induces an accelerated aging phenotype and oxidative stress in skeletal muscle of male rats.
Tarry-Adkins JL, Fernandez-Twinn DS, Chen JH, Hargreaves IP, Neergheen V, Aiken CE, Ozanne SE
Disease models & mechanisms 2016 Oct 1;9(10):1221-1229
Disease models & mechanisms 2016 Oct 1;9(10):1221-1229
Chlorogenic acid protects against liver fibrosis in vivo and in vitro through inhibition of oxidative stress.
Shi H, Shi A, Dong L, Lu X, Wang Y, Zhao J, Dai F, Guo X
Clinical nutrition (Edinburgh, Scotland) 2016 Dec;35(6):1366-1373
Clinical nutrition (Edinburgh, Scotland) 2016 Dec;35(6):1366-1373
PKCα promotes generation of reactive oxygen species via DUOX2 in hepatocellular carcinoma.
Wang J, Shao M, Liu M, Peng P, Li L, Wu W, Wang L, Duan F, Zhang M, Song S, Jia D, Ruan Y, Gu J
Biochemical and biophysical research communications 2015 Aug 7;463(4):839-45
Biochemical and biophysical research communications 2015 Aug 7;463(4):839-45
The phosphodiesterase-5 inhibitor vardenafil reduces oxidative stress while reversing pulmonary arterial hypertension.
Fan YF, Zhang R, Jiang X, Wen L, Wu DC, Liu D, Yuan P, Wang YL, Jing ZC
Cardiovascular research 2013 Aug 1;99(3):395-403
Cardiovascular research 2013 Aug 1;99(3):395-403
TIPE2, a novel regulator of immunity, protects against experimental stroke.
Zhang Y, Wei X, Liu L, Liu S, Wang Z, Zhang B, Fan B, Yang F, Huang S, Jiang F, Chen YH, Yi F
The Journal of biological chemistry 2012 Sep 21;287(39):32546-55
The Journal of biological chemistry 2012 Sep 21;287(39):32546-55
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The NOX2 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human NOX2. This antibody recognizes human,mouse,rat antigen. The NOX2 antibody has been validated for the following applications: ELISA, WB analysis.
