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- Antigen structure
- References [267]
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- Product number
- 19013-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- NOX2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated NOX2 antibody (Cat. #19013-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references CYBB-Mediated Ferroptosis Drives Podocyte Injury in Lupus Nephritis and Represents a Therapeutic Target.
Stromal cell-derived itaconate promotes endometriosis via macrophage NRF2 and lysosomal pH modulation.
Pregnancy precipitates metabolic imbalance and accelerates death in an animal model of mitochondrial cardiomyopathy.
Celastrol protects against renal tubular injury in early diabetic kidney disease through modulation of NOX2 and ferroptosis.
Gancao decoction ameliorated senecionine-induced Hepatic Sinusoidal Obstruction Syndrome in mice by inhibiting NET formation and senecionine bioactivation in liver.
Lithospermic Acid Improves Doxorubicin-Induced Cardiomyopathy Through Sirtuin-3-Mediated Deacetylation of p53.
Shikonin alleviates high-fat diet-induced vascular aging and dysfunction by inhibiting oxidative stress and mitochondrial damage.
Atractylenolide III improves ovarian dysfunction and endometrial receptivity in a PCOS rat model by regulating Cybb-mediated oxidative stress.
Inhibition of mitochondrial ROS turns LC3-associated phagocytosis to autophagy upon resveratrol treatment for group A Streptococcus clearance in endothelial cells.
Androsin alleviates colorectal cancer by inhibiting the PI3K/Akt-centered signaling pathway.
Mechanism of HAND2 Regulating Glycolytic Metabolism and Metastasis Through TLR4/NOX2/DUOX2 Signaling Axis in Cervical Cancer.
DECTIN-2 regulates macrophage M1 polarization via the SYK/ROS/JNK axis to influence the progress of apical periodontitis.
Gastrin releasing peptide receptor antagonism in the paraventricular nucleus exerts antihypertensive effects in 2K1C rats.
A Novel Murine Model to Study the Early Biological Events of Corticosteroid-Associated Osteonecrosis of the Femoral Head.
Celastrol nanomedicine eye drops restore redox homeostasis and prevents keratoconus progression via PI3K/AKT/AP-1 signaling.
[Isovitexin alleviates myocardial oxidative stress injury in diabetic mice by enhancing myocardial SIRT3 expression and reducing oxidative stress].
Mitigation of Oxidative Stress Pathways in the Diabetic Cornea and Lacrimal Glands Contributes to the Rapid Reversal of Diabetic Dry Eye by Naltrexone.
Urolithin A alleviates vascular remodeling through mitochondrial SIRT3-mediated SOD2 deacetylation and antioxidation in hypertensive rats.
CD36 serves as a potential drug-target to alleviate inflammation in atherosclerosis via leonurine-mediated blockade of its activation pocket.
Astaxanthin ameliorates allergic rhinitis via suppression of the HMGB1/TLR4 signaling pathway.
Macrophage KDM2A promotes atherosclerosis via regulating FYN and inducing inflammatory response.
Intermedin(1-53) Improves Atherosclerosis by Reducing Local Endothelial Damage via AMPK Signaling Pathway in Obese apoE-Deficient Mice.
Comprehensive Analysis of Ferroptosis Markers in Lupus Nephritis Based on Bioinformatics Analysis and Experimental Validation.
LYN and CYBB are pivotal immune and inflammatory genes as diagnostic biomarkers in recurrent spontaneous abortion.
Gypensapogenin I alleviates PANoptosis, ferroptosis, and oxidative stress in myocardial ischemic-reperfusion injury by targeting the NOX2/AMPK pathway.
TIMP1 inhibits Rac1-mediated ROS production to ameliorate blood-spinal cord barrier disruption in amyotrophic lateral sclerosis.
Gastrin-releasing peptide in the paraventricular nucleus exerts hypertensive effects in preeclampsia.
Protective effects of Ginkgolide B on myocardial ischemia reperfusion injury: role of the GAS6/Axl signaling pathway.
Transcription factor RUNX2 participates in astrocyte-mediated neuropathic pain via transcriptional activation of Ccl2.
Aerobic exercise alleviates chronic allergic airway inflammation by regulating the circMETTL9/EIF4A3/IGFBP3 axis.
Poliumoside Alleviates Neuroinflammation and Oxidative Stress After Spinal Cord Injury by Activating the PI3K/AKT/mTOR Signaling Pathway.
Scorpion Venom Heat-Resistant Synthetic Peptide Alleviates DSS-Induced Colitis via α7nAChR-Mediated Modulation of the JAK2/STAT3 Pathway.
Inhibition of PGK1 ameliorates acute kidney injury through inactivating the PKM2/ALOX12/ferroptosis pathway in a study with male mice.
Ershen Dan attenuates atherosclerosis by modulating the NOTCH1/NF-κB/NLRP3 signaling pathway to suppress M1 macrophage polarization.
Macrophage NADPH oxidase inhibition by ultralow-dose dextromethorphan alleviates DSS-induced inflammation and colitis.
Neutrophil extravasation and NETosis in decompression illness lung injury: A P-selectin/PSGL-1/NOX2/PAD4 axis governed pathway validated by multi-model interrogation.
Exercise-derived peptide confers protection against septic cardiomyopathy by enhancing CCAAT/enhancer binding protein β-mediated autophagy.
Quercetin ameliorates doxorubicin-induced atrial fibrillation via EGFR-mediated restoration of autophagic flux.
Sotagliflozin attenuates atrial oxidative stress and the susceptibility to atrial fibrillation by activating the NRF2/HO-1 pathway.
Wuling San ameliorates cerebral ischemia-reperfusion injury via suppression of the TRPM2/NLRP3 pathway.
Modulation of Osteogenic Differentiation by CYBB in Osteoporotic Models.
Dihydroartemisinin ameliorates hemarthrosis-induced cartilage degeneration by suppressing chondrocyte senescence via activation of Keap1-Nrf2 signaling pathway.
Cardiac PDK4 promotes neutrophilic PFKL methylation and drives the innate immune response in diabetic myocardial infarction.
Adiponectin ameliorates traumatic brain injury-induced ferroptosis through AMPK- ACC1 signaling pathway.
Porphyromonas gingivalis aggravates atherosclerotic plaque instability by promoting lipid-laden macrophage necroptosis.
Mangiferin Attenuates Myocardial Ischemia Reperfusion Injury by Regulating the GAS6/Axl Signaling Pathway.
Novel oral compound Z526 mitigates cancer-associated cachexia via intervening NF-κB signaling and oxidative stress.
Gallic acid alleviates ferroptosis by negatively regulating APOC3 and improves nerve function deficit caused by traumatic brain injury.
S-nitrosylation of peroxiredoxin 2 exacerbates hyperuricemia-induced renal injury through regulation of mitochondrial homeostasis.
S100A8 induces cyclophosphamide-induced alopecia via NCF2/NOX2-mediated ferroptosis.
Dectin-2 depletion alleviates osteoclast-induced bone loss in periodontitis via Syk/NOX2/ROS signaling.
Paeonol from Paeonia lactiflora attenuates calcification of aortic valvular interstitial cell by inhibiting activation of redox-sensitive NFκB/AKT/ERK1/2 pathway.
Celastrol improves endothelial function in diet-induced obesity mice via attenuating endoplasmic reticulum stress through the activation of AMPK pathway.
Autophagy hub-protein p62 orchestrates oxidative, endoplasmic reticulum stress, and inflammatory responses post-ischemia, exacerbating stroke outcome.
Ginsenoside Rh3-induced neurotoxicity involving the IP3R-Ca(2+)/NOX2/NF-κB signaling pathways.
Biochanin a Alleviated Doxorubicin-Induced Cardiotoxicity but Did not Interfere With the Antitumor Effect of Doxorubicin.
Exploring PU.1 as a Therapeutic Target to Mitigate Oxidative Stress and Inflammation in Peritoneal Dialysis-Induced Peritoneal Fibrosis.
Negative Air Ions Attenuate Nicotine-Induced Vascular Endothelial Dysfunction by Suppressing AP1-Mediated FN1 and SPP1.
Alleviation of fibrosis and oxidative stress in pressure overload-induced cardiac remodeling and heart failure via SIRT3 activation by colchicine.
Brain targeted lipid nanoparticles with Hv1 inhibitors alleviate neuroinflammation post-ischemic stroke.
GFOD1 regulates oxidative stress-induced damage in ADHD via NF-κB signaling pathway.
Isosteviol Sodium Promotes Neurological Function Recovery in a Model of Spinal Cord Injury in Rats.
Down-regulation of E2F1 attenuates UVB-induced human lens epithelial cell oxidative stress and pyroptosis through inhibiting NLRP3.
Downregulation of ferroptosis-related ATF3 alleviates lupus nephritis progression.
Inhibition of the FEN1-PBX1 axis elicits cellular senescence in breast cancer via the increased intracellular reactive oxygen species levels.
Oxidative stress mediated by the NOX2/ROS/NF-κB signaling axis is involved in rosacea.
Aprocitentan mitigates doxorubicin-induced cardiotoxicity by inhibiting cuproptosis, oxidative stress, and mitochondrial impairments via the activation of sirtuin 7.
Protective effect and mechanism of plant-derived Lactobacillus G11 on septic myocardial injury.
Ceria Nanoparticles Improve the Quality of Aging Oocytes in Mice by Enhancing ROS Scavenging Ability.
Spinal AT1R contributes to neuroinflammation and neuropathic pain via NOX2-dependent redox signaling in microglia.
Phillyrin prevents calcium oxalate kidney stones through the PPARγ signaling pathway.
Gut microbiota-derived butyrate prevents aortic dissection via GPR41.
Norepinephrine promotes oxidative stress in vascular adventitial fibroblasts via PKC/NFκB-mediated NOX2 upregulation.
Unveiling the role of Jagged2 in hypoxic pulmonary arterial hypertension: A NOX2-mediated pathway.
Inhibition of TRPC3-Nox2 Complex Formation Ameliorates Skeletal Muscle Atrophy.
Targeting NADPH oxidase 2 suppresses the growth of esophageal squamous cell carcinoma by regulating BTG2 pathway.
Targeting ER stress/ROS-driven VEGF signaling axis: AdipoRon as a multifunctional therapeutic agent for alkali burn-induced corneal neovascularization.
Cold exposure promotes the progression of osteoarthritis through downregulating APOE in cartilage.
CYBB as a potential therapeutic target through influencing ferroptosis and macrophage in ovarian cancer.
Age-Related Mitochondrial Alterations Contribute to Myocardial Responses During Sepsis.
Curcumin preserves bone health compromised by diabetes by inhibiting osteoporosis through regulation of the SIRT3/FoxO3a signalling pathway.
Obesity-induced activation of NADPH oxidase 2 prolongs cardiac repolarization via inhibiting K+ currents.
Annao Pingchong decoction attenuates oxidative stress and neuronal apoptosis following intracerebral hemorrhage via RAGE-NOX2/4 axis.
Probucol mitigates high-fat diet-induced cognitive and social impairments by regulating brain redox and insulin resistance.
Reversal of cholestatic liver disease by the inhibition of sphingosine 1-phosphate receptor 2 signaling.
NOX2 and NOX4 expression in monocytes and macrophages-extracellular vesicles in signalling and therapeutics.
Targeting mitochondrial dysfunction in atopic dermatitis with trilinolein: A triacylglycerol from the medicinal plant Cannabis fructus.
Melatonin alleviates aging-related heart failure through melatonin receptor 1A/B knockout in mice.
Dietary nitrate maintains homeostasis of oxidative stress and gut microbiota to promote flap survival in type 2 diabetes mellitus rats.
Activation of nuclear receptor pregnane-X-receptor protects against abdominal aortic aneurysm by inhibiting oxidative stress.
GDF15 attenuates sepsis-induced myocardial dysfunction by inhibiting cardiomyocytes ferroptosis via the SOCS1/GPX4 signaling pathway.
Inhibition of MST1 ameliorates neuronal apoptosis via GSK3β/β-TrCP/NRF2 pathway in spinal cord injury accompanied by diabetes.
Food therapy of scutellarein ameliorates pirarubicin‑induced cardiotoxicity in rats by inhibiting apoptosis and ferroptosis through regulation of NOX2‑induced oxidative stress.
Caffeic acid phenethyl ester inhibits neuro-inflammation and oxidative stress following spinal cord injury by mitigating mitochondrial dysfunction via the SIRT1/PGC1α/DRP1 signaling pathway.
FGF21 Inhibits Hypoxia/Reoxygenation-induced Renal Tubular Epithelial Cell Injury by Regulating the PPARγ/NF-κB Signaling Pathway.
Role of plasmacytoid dendritic cells in vascular dysfunction in mice with renovascular hypertension.
Intracellular and extracellular Cyclophilin a promote cardiac fibrosis through TGF-β signaling in response to angiotensin Ⅱ.
KLF6 silencing attenuates MCAO-induced brain injury and cognitive dysfunction via targeting ferroptosis and activating the Nrf2/HO-1 pathway.
Nicotinamide mononucleotide attenuates airway epithelial barrier dysfunction via inhibiting SIRT3 SUMOylation in asthma.
METTL3 silencing inhibits ferroptosis to suppress ovarian fibrosis in PCOS by upregulating m6A modification of GPX4.
Alizarin attenuates oxidative stress-induced mitochondrial damage in vascular dementia rats by promoting TRPM2 ubiquitination and proteasomal degradation via Smurf2.
Bone morphogenetic protein 4 inhibits corneal neovascularization by blocking NETs-induced disruption to corneal epithelial barrier.
Ruscogenin attenuates osteoarthritis by modulating oxidative stress-mediated macrophage reprogramming via directly targeting Sirt3.
Accumulation of Advanced Oxidation Protein Products Promotes Age-Related Decline of Type H Vessels in Bone.
Zinc promotes microbial p-coumaric acid production that protects against cholestatic liver injury.
EGFR-MEK1/2 cascade negatively regulates bactericidal function of bone marrow macrophages in mice with Staphylococcus aureus osteomyelitis.
NADPH oxidase-dependent free radical generation and protein adduct formation in neutrophils.
Quercetin Mitigates Lysophosphatidylcholine (LPC)-Induced Neutrophil Extracellular Traps (NETs) Formation through Inhibiting the P2X7R/P38MAPK/NOX2 Pathway.
Bioinformatic analysis reveals the relationship between macrophage infiltration and Cybb downregulation in hyperoxia-induced bronchopulmonary dysplasia.
Oxidative stress and regulation of adipogenic differentiation capacity by sirtuins in adipose stem cells derived from female patients of advancing age.
IL-1β mediates Candida tropicalis-induced immunosuppressive function of MDSCs to foster colorectal cancer.
The antihypertensive effect of Alizarin is achieved by activating VEGFR2/eNOS pathway, attenuating oxidative stress-induced mitochondrial damage and premature senescence.
Matrine Suppresses Arsenic-Induced Malignant Transformation of SV-HUC-1 Cells via NOX2.
Asprosin contributes to vascular remodeling in hypertensive rats via superoxide signaling.
Atorvastatin combined with imipenem alleviates lung injury in sepsis by inhibiting neutrophil extracellular trap formation via the ERK/NOX2 signaling pathway.
Mitochondrial complex I activity in microglia sustains neuroinflammation.
CYBB-Mediated Ferroptosis Associated with Immunosuppression in Mycobacterium leprae-Infected Monocyte-Derived Macrophages.
GKT137831 in combination with adipose-derived stem cells alleviates high glucose-induced inflammaging and improves diabetic wound healing.
Sphingolipid biosynthesis is essential for metabolic rewiring during T(H)17 cell differentiation.
Esculin targets TLR4 to protect against LPS-induced septic cardiomyopathy.
Nox2 inhibition reduces trophoblast ferroptosis in preeclampsia via the STAT3/GPX4 pathway.
Dapagliflozin ameliorates myocardial infarction injury through AMPKα-dependent regulation of oxidative stress and apoptosis.
Antigen stasis and airway nitrosative stress in human primary ciliary dyskinesia.
Adipocyte-Derived Exosomal NOX4-Mediated Oxidative Damage Induces Premature Placental Senescence in Obese Pregnancy.
Effects of liraglutide on astrocyte polarization and neuroinflammation in db/db mice: focus on iron overload and oxidative stress.
Identification and validation of immune-associated NETosis subtypes and biomarkers in anti-neutrophil cytoplasmic antibody associated glomerulonephritis.
FGL2 deficiency alleviates maternal inflammation-induced blood-brain barrier damage by blocking PI3K/NF-κB mediated endothelial oxidative stress.
Oscillatory shear stress promotes vein graft intimal hyperplasia via NADPH oxidase-related pathways.
Pure total flavonoids from citrus alleviate oxidative stress and inflammation in nonalcoholic fatty liver disease by regulating the miR-137-3p/NOXA2/NOX2 pathway.
A Novel NOX Inhibitor Alleviates Parkinson's Disease Pathology in PFF-Injected Mice.
Inhibition of AT1R/IP3/IP3R-mediated Ca(2+) release protects against calcium oxalate crystals-induced renal oxidative stress.
Niclosamide Inhibits Aortic Valve Interstitial Cell Calcification by Interfering with the GSK-3β/β-Catenin Signaling Pathway.
Transient receptor potential vanilloid 4 (TRPV4) in neutrophils enhances myocardial ischemia/reperfusion injury.
Glucocorticoid-induced activation of NOX/ROS/NF-κB signaling in MSCs contributes to the development of GONFH.
Intermittent fasting alleviates type 1 diabetes-induced cognitive dysfunction by improving the frontal cortical metabolic disorder.
The novel peptide athycaltide-1 attenuates Ang II-induced pathological myocardial hypertrophy by reducing ROS and inhibiting the activation of CaMKII and ERK1/2.
Colchicine protects against the development of experimental abdominal aortic aneurysm.
Short-chain acyl-CoA dehydrogenase is a potential target for the treatment of vascular remodelling.
Electroacupuncture alleviates early brain injury via modulating microglia polarization and suppressing neuroinflammation in a rat model of subarachnoid hemorrhage.
Lnc-17Rik promotes the immunosuppressive function of Myeloid-Derived suppressive cells in esophageal cancer.
Dioscin ameliorates silica-aggravated systemic lupus erythematosus via suppressing apoptosis and improving LC3-associated phagocytosis in MRL/lpr mice.
Capsaicin inhibits aortic valvular interstitial cell calcification via the redox-sensitive NFκB/AKT/ERK1/2 pathway.
Synergistic effect of elevated glucose levels with SARS-CoV-2 spike protein induced NOX-dependent ROS production in endothelial cells.
The pro-inflammatory signature of lipopolysaccharide in spontaneous contracting embryoid bodies differentiated from mouse embryonic stem cells.
Contemporary Antiretroviral Therapy Dysregulates Iron Transport and Augments Mitochondrial Dysfunction in HIV-Infected Human Microglia and Neural-Lineage Cells.
Dysregulated B7H4/JAK2/STAT3 Pathway Involves in Hypertriglyceridemia Acute Pancreatitis and Is Attenuated by Baicalin.
Stromal Vascular Fraction Restores Vasodilatory Function by Reducing Oxidative Stress in Aging-Induced Coronary Microvascular Disease.
Saxagliptin alleviates erectile dysfunction through increasing stromal cell-derived factor-1 in diabetes mellitus.
Acid sphingomyelinase promotes diabetic cardiomyopathy via NADPH oxidase 4 mediated apoptosis.
Adrenomedullin Improves Hypertension and Vascular Remodeling partly through the Receptor-Mediated AMPK Pathway in Rats with Obesity-Related Hypertension.
Exosomal RBP4 potentiated hepatic lipid accumulation and inflammation in high-fat-diet-fed mice by promoting M1 polarization of Kupffer cells.
Apolipoprotein C-III itself stimulates the Syk/cPLA2-induced inflammasome activation of macrophage to boost anti-tumor activity of CD8(+) T cell.
Nogo-B mediates endothelial oxidative stress and inflammation to promote coronary atherosclerosis in pressure-overloaded mouse hearts.
Comprehensive analysis and identification of prognostic biomarkers and immunotherapeutic targets in the NADPH oxidase family (and its regulatory subunits) in pancreatic ductal adenocarcinoma.
BMP4 inhibits corneal neovascularization by interfering with tip cells in angiogenesis.
Fibroblast growth factor 21 protects the liver from apoptosis in a type 1 diabetes mouse model via regulating L-lactate homeostasis.
Purinergic receptor P2X7 activates NOX2/JNK signaling to participate in granulosa cell inflammation and apoptosis in polycystic ovary syndrome.
Angiotensin II Increases Oxidative Stress and Inflammation in Female, But Not Male, Endothelial Cells.
SGLT2 inhibition ameliorates nano plastics-induced premature endothelial senescence and dysfunction.
Aerobic Exercise Training Improves Renal Injury in Spontaneously Hypertensive Rats by Increasing Renalase Expression in Medulla.
Lonicera caerulea Berry Polyphenols Extract Alleviates Exercise Fatigue in Mice by Reducing Oxidative Stress, Inflammation, Skeletal Muscle Cell Apoptosis, and by Increasing Cell Proliferation.
Recurrent Hypoglycemia Impaired Vascular Function in Advanced T2DM Rats by Inducing Pyroptosis.
Schisandrin B Diet Inhibits Oxidative Stress to Reduce Ferroptosis and Lipid Peroxidation to Prevent Pirarubicin-Induced Hepatotoxicity.
Angiotensin II Induces Cardiac Edema and Hypertrophic Remodeling through Lymphatic-Dependent Mechanisms.
Soluble Epoxide Hydrolase Inhibition Protected against Diabetic Cardiomyopathy through Inducing Autophagy and Reducing Apoptosis Relying on Nrf2 Upregulation and Transcription Activation.
Change in Oxidative Stress and Mitochondrial Dynamics in Response to Elevated Cold-Inducible RNA-Binding Protein in Cardiac Surgery-Associated Acute Kidney Injury.
Pyrrosia petiolosa Extract Ameliorates Ethylene Glycol-Induced Urolithiasis in Rats by Inhibiting Oxidative Stress and Inflammatory Response.
Rosmarinic Acid Ameliorates Pulmonary Ischemia/Reperfusion Injury by Activating the PI3K/Akt Signaling Pathway.
A Novel Compound, Tanshinol Borneol Ester, Ameliorates Pressure Overload-Induced Cardiac Hypertrophy by Inhibiting Oxidative Stress via the mTOR/β-TrCP/NRF2 Pathway.
Administration of USP7 inhibitor P22077 inhibited cardiac hypertrophy and remodeling in Ang II-induced hypertensive mice.
Interleukin 32 participates in cardiomyocyte-induced oxidative stress, inflammation and apoptosis during hypoxia/reoxygenation via the NOD2/NOX2/MAPK signaling pathway.
A dual Keap1 and p47(phox) inhibitor Ginsenoside Rb1 ameliorates high glucose/ox-LDL-induced endothelial cell injury and atherosclerosis.
Combination Treatment with Hydroxytyrosol and Vitamin E Improves NAFLD-Related Fibrosis.
Edaravone dexborneol protects cerebral ischemia reperfusion injury through activating Nrf2/HO-1 signaling pathway in mice.
Inhibition of Hypoxia-Inducible Factor Prolyl-Hydroxylase Modulates Platelet Function.
Suramin enhances chondrogenic properties by regulating the p67(phox)/PI3K/AKT/SOX9 signalling pathway.
Mycobacterium tuberculosis Utilizes Host Histamine Receptor H1 to Modulate Reactive Oxygen Species Production and Phagosome Maturation via the p38MAPK-NOX2 Axis.
Identification of a necroptosis-related prognostic gene signature associated with tumor immune microenvironment in cervical carcinoma and experimental verification.
Gut microbiome dysbiosis contributes to abdominal aortic aneurysm by promoting neutrophil extracellular trap formation.
The Clostridium Metabolite P-Cresol Sulfate Relieves Inflammation of Primary Biliary Cholangitis by Regulating Kupffer Cells.
Lipopolysaccharide induces placental mitochondrial dysfunction in murine and human systems by reducing MNRR1 levels via a TLR4-independent pathway.
Graphene oxide leads to mitochondrial-dependent apoptosis by activating ROS-p53-mPTP pathway in intestinal cells.
Impact of Selective Renal Afferent Denervation on Oxidative Stress and Vascular Remodeling in Spontaneously Hypertensive Rats.
Pu-erh Tea Restored Circadian Rhythm Disruption by Regulating Tryptophan Metabolism.
Prednisone Ameliorates Atrial Inflammation and Fibrosis in Atrial Tachypacing Dogs.
Effects of polystyrene nanoplastics on endothelium senescence and its underlying mechanism.
Disruption of mitochondrial redox homeostasis as a mechanism of antimony-induced reactive oxygen species and cytotoxicity.
In utero hypoxia attenuated acetylcholine-mediated vasodilatation via CHRM3/p-NOS3 in fetal sheep MCA: role of ROS/ERK1/2.
Accumulation of advanced oxidation protein products contributes to age-related impairment of gap junction intercellular communication in osteocytes of male mice.
Role of Nox4 in High Calcium-Induced Renal Oxidative Stress Damage and Crystal Deposition.
Reducing oxidative stress may be important for treating pirarubicin-induced cardiotoxicity with schisandrin B.
mTORC1 activation induced proximal tubular damage via the pentose phosphate pathway in lupus nephritis.
Chronic Sigma 1 receptor activation alleviates right ventricular dysfunction secondary to pulmonary arterial hypertension.
Honokiol improves endothelial function in type 2 diabetic rats via alleviating oxidative stress and insulin resistance.
A Novel NOX Inhibitor Treatment Attenuates Parkinson's Disease-Related Pathology in Mouse Models.
Electronic cigarette exposure causes vascular endothelial dysfunction due to NADPH oxidase activation and eNOS uncoupling.
Crocin Improves Endothelial Mitochondrial Dysfunction via GPx1/ROS/KCa3.1 Signal Axis in Diabetes.
Human Tissue Kallikrein 1 Is Downregulated in Elderly Human Prostates and Possesses Potential In Vitro Antioxidative and Antifibrotic Effects in Rodent Prostates.
Shenxian-Shengmai Oral Liquid Improves Sinoatrial Node Dysfunction through the PKC/NOX-2 Signaling Pathway.
Microglia-Derived Exosomes Improve Spinal Cord Functional Recovery after Injury via Inhibiting Oxidative Stress and Promoting the Survival and Function of Endothelia Cells.
17β-Estradiol promotes LC3B-associated phagocytosis in trained immunity of female mice against sepsis.
Iron Oxide Nanoparticles Combined with Cytosine Arabinoside Show Anti-Leukemia Stem Cell Effects on Acute Myeloid Leukemia by Regulating Reactive Oxygen Species.
Nox2 contributes to reactive oxygen species-induced redox imbalance in cancer-induced bone pain.
Nox2 impairs VEGF-A-induced angiogenesis in placenta via mitochondrial ROS-STAT3 pathway.
Compound essential oils relieve oxidative stress caused by PM(2) (.5) exposure by inhibiting autophagy through the AMPK/mTOR pathway.
Effects of different intensities of continuous training on vascular inflammation and oxidative stress in spontaneously hypertensive rats.
Aged Ripe Pu-erh Tea Reduced Oxidative Stress-Mediated Inflammation in Dextran Sulfate Sodium-Induced Colitis Mice by Regulating Intestinal Microbes.
Canagliflozin is a potential cardioprotective drug but exerts no significant effects on pirarubicin‑induced cardiotoxicity in rats.
The protective effect of harpagoside on angiotensin II (Ang II)-induced blood-brain barrier leakage in vitro.
Distinction between 2'- and 3'-Phosphate Isomers of a Fluorescent NADPH Analogue Led to Strong Inhibition of Cancer Cells Migration.
Mild hypothermia in rat with acute myocardial ischaemia-reperfusion injury complicating severe sepsis.
Protective effect of recombinant Lactobacillus plantarum against H(2)O(2)-induced oxidative stress in HUVEC cells.
C-C motif ligand 8 promotes atherosclerosis via NADPH oxidase 2/reactive oxygen species-induced endothelial permeability increase.
Sirtuin 1 ameliorates defenestration in hepatic sinusoidal endothelial cells during liver fibrosis via inhibiting stress-induced premature senescence.
Scoparone alleviates Ang II-induced pathological myocardial hypertrophy in mice by inhibiting oxidative stress.
Hsa_circ_0005915 promotes N,N-dimethylformamide-induced oxidative stress in HL-7702 cells through NRF2/ARE axis.
Protective effect of scorpion venom heat-resistant synthetic peptide against PM(2.5)-induced microglial polarization via TLR4-mediated autophagy activating PI3K/AKT/NF-κB signaling pathway.
Silencing COX-2 blocks PDK1/TRAF4-induced AKT activation to inhibit fibrogenesis during skeletal muscle atrophy.
RND3 attenuates oxidative stress and vascular remodeling in spontaneously hypertensive rat via inhibiting ROCK1 signaling.
Normothermic machine perfusion attenuates hepatic ischaemia-reperfusion injury by inhibiting CIRP-mediated oxidative stress and mitochondrial fission.
Maternal supply of cysteamine alleviates oxidative stress and enhances angiogenesis in porcine placenta.
Ginkgetin Alleviates Inflammation, Oxidative Stress, and Apoptosis Induced by Hypoxia/Reoxygenation in H9C2 Cells via Caspase-3 Dependent Pathway.
Brevilin A Inhibits STAT3 Signaling and Induces ROS-Dependent Apoptosis, Mitochondrial Stress and Endoplasmic Reticulum Stress in MCF-7 Breast Cancer Cells.
Targeting Epstein-Barr virus oncoprotein LMP1-mediated high oxidative stress suppresses EBV lytic reactivation and sensitizes tumors to radiation therapy.
Magnesium isoglycyrrhizinate alleviates fructose-induced liver oxidative stress and inflammatory injury through suppressing NOXs.
Protective effect of Berberine on reproductive function and spermatogenesis in diabetic rats via inhibition of ROS/JAK2/NFκB pathway.
MiR155-5p Inhibits Cell Migration and Oxidative Stress in Vascular Smooth Muscle Cells of Spontaneously Hypertensive Rats.
Cathelicidin Modulates Vascular Smooth Muscle Cell Phenotypic Switching through ROS/IL-6 Pathway.
p47phox deficiency impairs platelet function and protects mice against arterial and venous thrombosis.
The Role of Testosterone in Amplifying the Effect of a Phosphodiesterase Type 5 Inhibitor After Pelvic Irradiation.
Increased Blood Pressure Causes Lymphatic Endothelial Dysfunction via Oxidative Stress in Spontaneously Hypertensive Rats.
BCL6 Attenuates Proliferation and Oxidative Stress of Vascular Smooth Muscle Cells in Hypertension.
Propofol Alleviates DNA Damage Induced by Oxygen Glucose Deprivation and Reperfusion via FoxO1 Nuclear Translocation in H9c2 Cells.
Protective Effects of 18β-Glycyrrhetinic Acid on Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats.
Human tissue kallikrein-1 protects against the development of erectile dysfunction in a rat model of hyperhomocysteinemia.
Astragaloside IV alleviates doxorubicin induced cardiomyopathy by inhibiting NADPH oxidase derived oxidative stress.
Allicin ameliorates obesity comorbid depressive-like behaviors: involvement of the oxidative stress, mitochondrial function, autophagy, insulin resistance and NOX/Nrf2 imbalance in mice.
(Pro)renin Receptor is Involved in Myocardial Damage in Alcoholic Cardiomyopathy.
MicroRNA-24 inhibits the oxidative stress induced by vascular injury by activating the Nrf2/Ho-1 signaling pathway.
Exogenous hydrogen sulfide protects against high glucose-induced apoptosis and oxidative stress by inhibiting the STAT3/HIF-1α pathway in H9c2 cardiomyocytes.
Role of JAK2 in the Pathogenesis of Diabetic Erectile Dysfunction and an Intervention With Berberine.
Chronic fetal hypoxia disrupts the peri-conceptual environment in next-generation adult female rats.
Growth differentiation factor 11 is involved in isoproterenol‑induced heart failure.
Oxidative and endoplasmic reticulum stresses are involved in palmitic acid-induced H9c2 cell apoptosis.
Chronic gestational hypoxia accelerates ovarian aging and lowers ovarian reserve in next-generation adult rats.
Testosterone preserves endothelial function through regulation of S1P1/Akt/FOXO3a signalling pathway in the rat corpus cavernosum.
Sensory plasticity of carotid body is correlated with oxidative stress in paraventricular nucleus during chronic intermittent hypoxia.
Inhibiting inflammation and modulating oxidative stress in oxalate-induced nephrolithiasis with the Nrf2 activator dimethyl fumarate.
Calcium Release from Endoplasmic Reticulum Involves Calmodulin-Mediated NADPH Oxidase-Derived Reactive Oxygen Species Production in Endothelial Cells.
Downregulated Expression of Solute Carrier Family 26 Member 6 in NRK-52E Cells Attenuates Oxalate-Induced Intracellular Oxidative Stress.
Losartan Ameliorates Calcium Oxalate-Induced Elevation of Stone-Related Proteins in Renal Tubular Cells by Inhibiting NADPH Oxidase and Oxidative Stress.
Notch inhibitor can attenuate apparent diffusion coefficient and improve neurological function through downregulating NOX2-ROS in severe traumatic brain injury.
BRG1 regulates NOX gene transcription in endothelial cells and contributes to cardiac ischemia-reperfusion injury.
Myocardin-related transcription factor A (MRTF-A) contributes to acute kidney injury by regulating macrophage ROS production.
Lipoxin A4 improves erectile dysfunction in rats with type I diabetes by inhibiting oxidative stress and corporal fibrosis.
Argirein alleviates vascular endothelial insulin resistance through suppressing the activation of Nox4-dependent O(2)(-) production in diabetic rats.
Megakaryocytic Leukemia 1 Bridges Epigenetic Activation of NADPH Oxidase in Macrophages to Cardiac Ischemia-Reperfusion Injury.
MitoTEMPO Prevents Oxalate Induced Injury in NRK-52E Cells via Inhibiting Mitochondrial Dysfunction and Modulating Oxidative Stress.
Berberine ameliorates fatty acid-induced oxidative stress in human hepatoma cells.
Therapeutic effect of human ghrelin and growth hormone: Attenuation of immunosuppression in septic aged rats.
Activation of ATP-sensitive potassium channel by iptakalim normalizes stress-induced HPA axis disorder and depressive behaviour by alleviating inflammation and oxidative stress in mouse hypothalamus.
Nitro-oleic acid ameliorates oxygen and glucose deprivation/re-oxygenation triggered oxidative stress in renal tubular cells via activation of Nrf2 and suppression of NADPH oxidase.
Poor maternal nutrition and accelerated postnatal growth induces an accelerated aging phenotype and oxidative stress in skeletal muscle of male rats.
Chlorogenic acid protects against liver fibrosis in vivo and in vitro through inhibition of oxidative stress.
PKCα promotes generation of reactive oxygen species via DUOX2 in hepatocellular carcinoma.
The phosphodiesterase-5 inhibitor vardenafil reduces oxidative stress while reversing pulmonary arterial hypertension.
TIPE2, a novel regulator of immunity, protects against experimental stroke.
Wang B, Jiang H, Wu D, Liu M, Chen H, Zhao S, Yan Y, Li S, Fang X, Wu R
Journal of inflammation research 2026;19:575320
Journal of inflammation research 2026;19:575320
Stromal cell-derived itaconate promotes endometriosis via macrophage NRF2 and lysosomal pH modulation.
Zhong Z, Wang S, Ren Q, Jiao X, Xu L, Dong X, Li N, Guan H, Chu R, Yuan M, Liu J, Du Y, Wei K, Yan L, Wang G
Redox biology 2026 May;92:104101
Redox biology 2026 May;92:104101
Pregnancy precipitates metabolic imbalance and accelerates death in an animal model of mitochondrial cardiomyopathy.
Sayles NM, Casalena G, Zhao D, Dellinger RW, Holmes HE, Manzo O, Galkin A, Di Lorenzo A, Manfredi G
Molecular metabolism 2026 May;107:102352
Molecular metabolism 2026 May;107:102352
Celastrol protects against renal tubular injury in early diabetic kidney disease through modulation of NOX2 and ferroptosis.
Ma D, Dai T, Wang D, Zhang J, Zeng C, Dai S, Li W, Shan X, Li H, Hou Y, Guo M
International immunopharmacology 2026 May 15;177:116533
International immunopharmacology 2026 May 15;177:116533
Gancao decoction ameliorated senecionine-induced Hepatic Sinusoidal Obstruction Syndrome in mice by inhibiting NET formation and senecionine bioactivation in liver.
Zhang S, Yan D, Cheng S, Jin J, Cui J, Liu C, Li Y, Qiu F
Journal of ethnopharmacology 2026 May 10;362:121356
Journal of ethnopharmacology 2026 May 10;362:121356
Lithospermic Acid Improves Doxorubicin-Induced Cardiomyopathy Through Sirtuin-3-Mediated Deacetylation of p53.
Zhao Y, Xu T, Ye C, Zhang K, Heng X, Huang S, Chen Y, Guo Y, Shao S, Wen Z, Shao C, Lu X, Sun N, Yang H
Phytotherapy research : PTR 2026 Mar;40(3):965-985
Phytotherapy research : PTR 2026 Mar;40(3):965-985
Shikonin alleviates high-fat diet-induced vascular aging and dysfunction by inhibiting oxidative stress and mitochondrial damage.
Ren GQ, Liu HJ, Guo YQ, He ML, Li J, Li ZX, Jia CH, Liu T, Yang J
Molecular biology reports 2026 Mar 4;53(1)
Molecular biology reports 2026 Mar 4;53(1)
Atractylenolide III improves ovarian dysfunction and endometrial receptivity in a PCOS rat model by regulating Cybb-mediated oxidative stress.
Bai C, Liu J
Naunyn-Schmiedeberg's archives of pharmacology 2026 Mar 30;
Naunyn-Schmiedeberg's archives of pharmacology 2026 Mar 30;
Inhibition of mitochondrial ROS turns LC3-associated phagocytosis to autophagy upon resveratrol treatment for group A Streptococcus clearance in endothelial cells.
Cheng YL, Su MS, Liao CC, Chang TW, Hsieh YC, Lu SL, Omori H, Noda T, Chu YL, Chen CL, Lin YS, Wu JJ
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 2026 Mar 17;
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 2026 Mar 17;
Androsin alleviates colorectal cancer by inhibiting the PI3K/Akt-centered signaling pathway.
Zhang Y, Luo H, Ma P, Leng Y, Tan Y, Zhuo S, Tan C, Xu D
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2026 Mar 1;30(2):155-168
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2026 Mar 1;30(2):155-168
Mechanism of HAND2 Regulating Glycolytic Metabolism and Metastasis Through TLR4/NOX2/DUOX2 Signaling Axis in Cervical Cancer.
Yang H, Li Y, Xiao Z, Kuang M
Molecular carcinogenesis 2026 Jun;65(6):699-714
Molecular carcinogenesis 2026 Jun;65(6):699-714
DECTIN-2 regulates macrophage M1 polarization via the SYK/ROS/JNK axis to influence the progress of apical periodontitis.
Lu S, Liao Y, Hu Y, Liu X, Sheng Y, Ye W, Zhao Y, Ji Y, Meng L
International immunopharmacology 2026 Jul 1;180:116694
International immunopharmacology 2026 Jul 1;180:116694
Gastrin releasing peptide receptor antagonism in the paraventricular nucleus exerts antihypertensive effects in 2K1C rats.
Wang XM, Liu JJ, Wang YP, Bai C, Issotina Zibrila A, Xia WJ, Yang RN, Kang YM, Yu XJ
Toxicology and applied pharmacology 2026 Jan;506:117620
Toxicology and applied pharmacology 2026 Jan;506:117620
A Novel Murine Model to Study the Early Biological Events of Corticosteroid-Associated Osteonecrosis of the Femoral Head.
Shinohara I, Susuki Y, Chow SK, Cheung P, Moses AS, Murayama M, Morita M, Uno T, Gao Q, Ma C, Igei T, Beinat C, Goodman SB
Bioengineering (Basel, Switzerland) 2026 Jan 20;13(1)
Bioengineering (Basel, Switzerland) 2026 Jan 20;13(1)
Celastrol nanomedicine eye drops restore redox homeostasis and prevents keratoconus progression via PI3K/AKT/AP-1 signaling.
Liu R, Ma R, Zhang N, Geng X, Li J, Zhu L, Li Z
Redox biology 2026 Feb;89:103990
Redox biology 2026 Feb;89:103990
[Isovitexin alleviates myocardial oxidative stress injury in diabetic mice by enhancing myocardial SIRT3 expression and reducing oxidative stress].
Peng Y, Jiang Y, Ma D, He A, Lü D, Luo M, Luo S
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2026 Feb 20;46(2):316-324
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2026 Feb 20;46(2):316-324
Mitigation of Oxidative Stress Pathways in the Diabetic Cornea and Lacrimal Glands Contributes to the Rapid Reversal of Diabetic Dry Eye by Naltrexone.
Krebs AK, Diaz D, Sassani JW, Zagon IS, McLaughlin PJ
Investigative ophthalmology & visual science 2026 Feb 2;67(2):23
Investigative ophthalmology & visual science 2026 Feb 2;67(2):23
Urolithin A alleviates vascular remodeling through mitochondrial SIRT3-mediated SOD2 deacetylation and antioxidation in hypertensive rats.
Dai M, Wang YM, Dong HK, Xu XY, Wang JX, Zhu GQ, Zheng F
Redox report : communications in free radical research 2026 Dec;31(1):2622255
Redox report : communications in free radical research 2026 Dec;31(1):2622255
CD36 serves as a potential drug-target to alleviate inflammation in atherosclerosis via leonurine-mediated blockade of its activation pocket.
Lin G, Chi AQ, Cai SY, Zhang YM, Ren YC, Lu X, Sun C, Mu XP, Zhang IY, Weng JW, Li MY, Chen Y, Zhu YZ, Tao BB, Zhu YC
Free radical biology & medicine 2026 Apr 12;251:256-275
Free radical biology & medicine 2026 Apr 12;251:256-275
Astaxanthin ameliorates allergic rhinitis via suppression of the HMGB1/TLR4 signaling pathway.
Lei X, Pan J, Deng K
Central-European journal of immunology 2025;50(3):276-289
Central-European journal of immunology 2025;50(3):276-289
Macrophage KDM2A promotes atherosclerosis via regulating FYN and inducing inflammatory response.
Xue Y, Peng Y, Jin L, Liu L, Liu Q, Yuan X, Wang J, Zhao M, Zhang W, Luo S, Li Y, Luo M, Huang L
International journal of biological sciences 2025;21(6):2780-2805
International journal of biological sciences 2025;21(6):2780-2805
Intermedin(1-53) Improves Atherosclerosis by Reducing Local Endothelial Damage via AMPK Signaling Pathway in Obese apoE-Deficient Mice.
Zhu HX, Ren JL, Cao WJ, Wang R, Chen LL, Gao Q, Zhou YB
Journal of inflammation research 2025;18:6583-6596
Journal of inflammation research 2025;18:6583-6596
Comprehensive Analysis of Ferroptosis Markers in Lupus Nephritis Based on Bioinformatics Analysis and Experimental Validation.
Zhang S, Hu W, Huang C, Lin X, Chen X
Journal of inflammation research 2025;18:10855-10871
Journal of inflammation research 2025;18:10855-10871
LYN and CYBB are pivotal immune and inflammatory genes as diagnostic biomarkers in recurrent spontaneous abortion.
Wu Z, Lin Q, Zhou Z, Xie Y, Huang L, Sheng L, Shi Q, Ke Y
Frontiers in immunology 2025;16:1568536
Frontiers in immunology 2025;16:1568536
Gypensapogenin I alleviates PANoptosis, ferroptosis, and oxidative stress in myocardial ischemic-reperfusion injury by targeting the NOX2/AMPK pathway.
Chen Y, Guan B, Lu J, Yan X, Huang C, Qiu Y, Li X, Sun X, Chen L, Li W, Mao W, Sun Z, Xu B, Li S, Chen C
Frontiers in cell and developmental biology 2025;13:1623846
Frontiers in cell and developmental biology 2025;13:1623846
TIMP1 inhibits Rac1-mediated ROS production to ameliorate blood-spinal cord barrier disruption in amyotrophic lateral sclerosis.
Tang J, Kang Y, Chen Q, Zhang B, Shang N, Lan J, Wu L, Peng Y
Neurobiology of disease 2025 Sep;213:106987
Neurobiology of disease 2025 Sep;213:106987
Gastrin-releasing peptide in the paraventricular nucleus exerts hypertensive effects in preeclampsia.
Wang X, Ali MA, Liu X, Zeng M, Zeng Z, Yuan M, Issotina Zibrila A, Liu S, Ping N, Kang Y, Li X, Liu J
Neurochemistry international 2025 Sep;188:106004
Neurochemistry international 2025 Sep;188:106004
Protective effects of Ginkgolide B on myocardial ischemia reperfusion injury: role of the GAS6/Axl signaling pathway.
Liu H, Lei W, Ren Y, Tian J, Wang D, Tang Y, Zhou S, Huang C, Huang G, Yang Y, Liang Z
Chemico-biological interactions 2025 Sep 5;418:111607
Chemico-biological interactions 2025 Sep 5;418:111607
Transcription factor RUNX2 participates in astrocyte-mediated neuropathic pain via transcriptional activation of Ccl2.
Shen W, Song S, Zhao X, Li D, Liu J, Yue S
Biochemical and biophysical research communications 2025 Sep 1;777:152263
Biochemical and biophysical research communications 2025 Sep 1;777:152263
Aerobic exercise alleviates chronic allergic airway inflammation by regulating the circMETTL9/EIF4A3/IGFBP3 axis.
Wang H, Jia Y, Ma B, Gao T, Wei H, Li D, Gu J, Chen O, Yue S
Cellular signalling 2025 Oct;134:111889
Cellular signalling 2025 Oct;134:111889
Poliumoside Alleviates Neuroinflammation and Oxidative Stress After Spinal Cord Injury by Activating the PI3K/AKT/mTOR Signaling Pathway.
Li Q, Hong H, Xu G, Xia M, Wang T, Zhou Z, Huang J, Fu Q, Cui Z
Journal of integrative neuroscience 2025 Oct 29;24(10):43900
Journal of integrative neuroscience 2025 Oct 29;24(10):43900
Scorpion Venom Heat-Resistant Synthetic Peptide Alleviates DSS-Induced Colitis via α7nAChR-Mediated Modulation of the JAK2/STAT3 Pathway.
Cheng K, He G, Li X, Li Y, Cui X, Wu X, Hong JS, Zhao J, Li S, Guo Y
Antioxidants (Basel, Switzerland) 2025 Oct 28;14(11)
Antioxidants (Basel, Switzerland) 2025 Oct 28;14(11)
Inhibition of PGK1 ameliorates acute kidney injury through inactivating the PKM2/ALOX12/ferroptosis pathway in a study with male mice.
Zhu XX, Meng XY, Zhang AY, Zhao CY, Wei YT, Wen YY, Su JB, Fu X, Chen G, Xu AJ, Wang MY, Ji LM, Bao N, Bao ZY, Li N, Lu QB, Sun HJ
Nature communications 2025 Oct 24;16(1):9436
Nature communications 2025 Oct 24;16(1):9436
Ershen Dan attenuates atherosclerosis by modulating the NOTCH1/NF-κB/NLRP3 signaling pathway to suppress M1 macrophage polarization.
Zhao W, Wang H, Peng S, Wei Q, Zhang L, Li Y, Yang W
Chinese medicine 2025 Oct 23;20(1):178
Chinese medicine 2025 Oct 23;20(1):178
Macrophage NADPH oxidase inhibition by ultralow-dose dextromethorphan alleviates DSS-induced inflammation and colitis.
Li Y, Hou L, Cheng K, He G, Hong JS, Li S, Zhao J, Guo Y
Free radical biology & medicine 2025 Nov;239:189-201
Free radical biology & medicine 2025 Nov;239:189-201
Neutrophil extravasation and NETosis in decompression illness lung injury: A P-selectin/PSGL-1/NOX2/PAD4 axis governed pathway validated by multi-model interrogation.
Li Z, Wang S, Bai Y, Liu S, Huang J, You Y, Li J, Yu X, Han Y, Bao X
Free radical biology & medicine 2025 Nov;239:14-26
Free radical biology & medicine 2025 Nov;239:14-26
Exercise-derived peptide confers protection against septic cardiomyopathy by enhancing CCAAT/enhancer binding protein β-mediated autophagy.
Huang X, Xu K, Wang Y, Xiao Q, Ci H, Fu X, Li Y, Zhuang F, Cai Z, Zhou G, Huo H, He B, Wang X, Shen L
Cellular and molecular life sciences : CMLS 2025 Nov 25;82(1):421
Cellular and molecular life sciences : CMLS 2025 Nov 25;82(1):421
Quercetin ameliorates doxorubicin-induced atrial fibrillation via EGFR-mediated restoration of autophagic flux.
Bian WH, Wang SH, Kang ZC, Xu Y, Li YN, Yang MZ, Yang JH, Liu JY, Cheng YL, Chang D, Xie X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157357
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157357
Sotagliflozin attenuates atrial oxidative stress and the susceptibility to atrial fibrillation by activating the NRF2/HO-1 pathway.
Li F, Xie M, Zeng G, Zhu J, Zhou J, Tan S, Lin Q, Liu Q
International immunopharmacology 2025 Nov 14;165:115461
International immunopharmacology 2025 Nov 14;165:115461
Wuling San ameliorates cerebral ischemia-reperfusion injury via suppression of the TRPM2/NLRP3 pathway.
Li H, Tao D, Chen Y, Deng Y, Wei W, Xue X
European journal of medical research 2025 Nov 10;30(1):1096
European journal of medical research 2025 Nov 10;30(1):1096
Modulation of Osteogenic Differentiation by CYBB in Osteoporotic Models.
Wang Z, Xu C, Liu Y, Duan K, Zhu Z, Guan J
IUBMB life 2025 May;77(5):e70023
IUBMB life 2025 May;77(5):e70023
Dihydroartemisinin ameliorates hemarthrosis-induced cartilage degeneration by suppressing chondrocyte senescence via activation of Keap1-Nrf2 signaling pathway.
Zeng Q, Feng Y, Huang H, Zou K, Chen W, Li X, Huang Y, Wang W, Yuan W, Wang P, Tong P, Jin H, Chen J
Journal of orthopaedic translation 2025 May;52:192-208
Journal of orthopaedic translation 2025 May;52:192-208
Cardiac PDK4 promotes neutrophilic PFKL methylation and drives the innate immune response in diabetic myocardial infarction.
Yang S, Yan L, Chen L, Su G, Yang L, Gong L, Liu L
Pharmacological research 2025 May;215:107731
Pharmacological research 2025 May;215:107731
Adiponectin ameliorates traumatic brain injury-induced ferroptosis through AMPK- ACC1 signaling pathway.
Ge Y, Wang T, Hu Q, Wu X, Cai Y, Xie W, Zhang S, Wang B, Wang J, Feng T, Feng D, Ge S, Guo H, Qu Y, Liu H
Brain, behavior, and immunity 2025 May;126:160-175
Brain, behavior, and immunity 2025 May;126:160-175
Porphyromonas gingivalis aggravates atherosclerotic plaque instability by promoting lipid-laden macrophage necroptosis.
Huang X, Xie M, Wang Y, Lu X, Mei F, Zhang K, Yang X, Chen G, Yin Y, Feng G, Song W, Dong N, Deng X, Wang S, Chen L
Signal transduction and targeted therapy 2025 May 23;10(1):171
Signal transduction and targeted therapy 2025 May 23;10(1):171
Mangiferin Attenuates Myocardial Ischemia Reperfusion Injury by Regulating the GAS6/Axl Signaling Pathway.
Zhao A, Lei W, Tian J, Wu X, Li M, Zhang Y, Wu X, Xu X, Tang J, Yang Y, Jin Z
Phytotherapy research : PTR 2025 Mar;39(3):1388-1402
Phytotherapy research : PTR 2025 Mar;39(3):1388-1402
Novel oral compound Z526 mitigates cancer-associated cachexia via intervening NF-κB signaling and oxidative stress.
Gu X, Lu S, Xu S, Li Y, Fan M, Lin G, Liu Y, Zhao Y, Zhao W, Liu X, Dong X, Zhang X
Genes & diseases 2025 Mar;12(2):101292
Genes & diseases 2025 Mar;12(2):101292
Gallic acid alleviates ferroptosis by negatively regulating APOC3 and improves nerve function deficit caused by traumatic brain injury.
Liu Y, Fu X, Li J, Guo J, Zhao Z, Zheng J
Scientific reports 2025 Mar 6;15(1):7815
Scientific reports 2025 Mar 6;15(1):7815
S-nitrosylation of peroxiredoxin 2 exacerbates hyperuricemia-induced renal injury through regulation of mitochondrial homeostasis.
Han F, Dong Y, Liu Q, Song L, Guo H, Zhu L, Sun B, Zhao W, Chen L
Free radical biology & medicine 2025 Mar 16;230:66-78
Free radical biology & medicine 2025 Mar 16;230:66-78
S100A8 induces cyclophosphamide-induced alopecia via NCF2/NOX2-mediated ferroptosis.
Xu W, Li Y, Wan S, Zhang B, Wei D, Zhang H, Jin X, Xie B, Guan C, Song X
Free radical biology & medicine 2025 Mar 16;230:112-126
Free radical biology & medicine 2025 Mar 16;230:112-126
Dectin-2 depletion alleviates osteoclast-induced bone loss in periodontitis via Syk/NOX2/ROS signaling.
Ye W, Liao Y, Liu X, Wang Y, Li T, Zhao Y, He Z, Chen J, Yin M, Sheng Y, Du Y, Ji Y, He H
Free radical biology & medicine 2025 Mar 1;229:13-29
Free radical biology & medicine 2025 Mar 1;229:13-29
Paeonol from Paeonia lactiflora attenuates calcification of aortic valvular interstitial cell by inhibiting activation of redox-sensitive NFκB/AKT/ERK1/2 pathway.
Gwak YH, Shiwakoti S, Ko JY, Sim HH, Lee JH, Kim HJ, Oak MH
Food science and biotechnology 2025 Jun;34(10):2269-2279
Food science and biotechnology 2025 Jun;34(10):2269-2279
Celastrol improves endothelial function in diet-induced obesity mice via attenuating endoplasmic reticulum stress through the activation of AMPK pathway.
Yu C, Lin W, Yang J, Jiang Q, Liu W, Liu H, Lin Y, Wang L, Chen L, Huang Y, Chen L
Molecular medicine (Cambridge, Mass.) 2025 Jun 11;31(1):233
Molecular medicine (Cambridge, Mass.) 2025 Jun 11;31(1):233
Autophagy hub-protein p62 orchestrates oxidative, endoplasmic reticulum stress, and inflammatory responses post-ischemia, exacerbating stroke outcome.
Quan X, Yang Y, Liu X, Kaltwasser B, Pillath-Eilers M, Walkenfort B, Voortmann S, Mohamud Yusuf A, Hagemann N, Wang C, Hasenberg M, Hermann DM, Brockmeier U
Redox biology 2025 Jul;84:103700
Redox biology 2025 Jul;84:103700
Ginsenoside Rh3-induced neurotoxicity involving the IP3R-Ca(2+)/NOX2/NF-κB signaling pathways.
Wang Y, Chen J, Li S, Cai Z
Journal of natural medicines 2025 Jul;79(4):791-806
Journal of natural medicines 2025 Jul;79(4):791-806
Biochanin a Alleviated Doxorubicin-Induced Cardiotoxicity but Did not Interfere With the Antitumor Effect of Doxorubicin.
Yang Y, Feng Z, Zhou F, Sun X, Shang J, Zhang N, Xia Y, Xie Y
Phytotherapy research : PTR 2025 Jul;39(7):3241-3253
Phytotherapy research : PTR 2025 Jul;39(7):3241-3253
Exploring PU.1 as a Therapeutic Target to Mitigate Oxidative Stress and Inflammation in Peritoneal Dialysis-Induced Peritoneal Fibrosis.
Zhong S, Su W, Wang Y, Liu D, Li X, Ma F, Xu L, Gao J, Wang H, Sun J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jul 15;39(13):e70766
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jul 15;39(13):e70766
Negative Air Ions Attenuate Nicotine-Induced Vascular Endothelial Dysfunction by Suppressing AP1-Mediated FN1 and SPP1.
Xiao S, Wei T, Xiao M, Shan M, An Z, Li N, Zhou J, Zhao S, Lu X
Antioxidants (Basel, Switzerland) 2025 Jul 14;14(7)
Antioxidants (Basel, Switzerland) 2025 Jul 14;14(7)
Alleviation of fibrosis and oxidative stress in pressure overload-induced cardiac remodeling and heart failure via SIRT3 activation by colchicine.
Wu M, Chen G, Peng Y, Luo S
Biochemical and biophysical research communications 2025 Jul 12;770:151957
Biochemical and biophysical research communications 2025 Jul 12;770:151957
Brain targeted lipid nanoparticles with Hv1 inhibitors alleviate neuroinflammation post-ischemic stroke.
Yang Z, Jin L, Li L, Wu Y, Liu W, Feng X, Li L, Jin F, Bi Y, Li R, Guo S, Wang Y, Wei B, Liu Y, Li X, Duan C
Journal of nanobiotechnology 2025 Jul 1;23(1):464
Journal of nanobiotechnology 2025 Jul 1;23(1):464
GFOD1 regulates oxidative stress-induced damage in ADHD via NF-κB signaling pathway.
Zheng ML, Yang ZH, He B, Sun X, Zhan YT, Shao AQ, Hong YC, Yin CX, Wang MZ, Ba YC, Ye P
Brain research 2025 Jul 1;1858:149605
Brain research 2025 Jul 1;1858:149605
Isosteviol Sodium Promotes Neurological Function Recovery in a Model of Spinal Cord Injury in Rats.
Zhang T, Zhang T, Yu H, Chi L
Immunity, inflammation and disease 2025 Jan;13(1):e70110
Immunity, inflammation and disease 2025 Jan;13(1):e70110
Down-regulation of E2F1 attenuates UVB-induced human lens epithelial cell oxidative stress and pyroptosis through inhibiting NLRP3.
Wang F, Yang F, Yang G, Zhou Q, Lv H
Human & experimental toxicology 2025 Jan-Dec;44:9603271241309258
Human & experimental toxicology 2025 Jan-Dec;44:9603271241309258
Downregulation of ferroptosis-related ATF3 alleviates lupus nephritis progression.
Xiao G, Tang S, Zhang Y, Yuan Q, Sun D, Wang W
Gene 2025 Jan 20;934:149009
Gene 2025 Jan 20;934:149009
Inhibition of the FEN1-PBX1 axis elicits cellular senescence in breast cancer via the increased intracellular reactive oxygen species levels.
Wu M, Wu B, Huang X, Wang Z, Zhu M, Zhu Y, Yu L, Liu J
Journal of translational medicine 2025 Feb 28;23(1):248
Journal of translational medicine 2025 Feb 28;23(1):248
Oxidative stress mediated by the NOX2/ROS/NF-κB signaling axis is involved in rosacea.
Wang Y, Long L, Chen M, Li J
Archives of dermatological research 2025 Feb 27;317(1):505
Archives of dermatological research 2025 Feb 27;317(1):505
Aprocitentan mitigates doxorubicin-induced cardiotoxicity by inhibiting cuproptosis, oxidative stress, and mitochondrial impairments via the activation of sirtuin 7.
Chen YF, Qi RQ, Zhao L, Liang LR, Song JW, Zhou XY, Chen YH, Wang SY, Wang Q, Liu Y, Dong Y, Liu XY, Li J, Zhong JC
International immunopharmacology 2025 Feb 20;148:114141
International immunopharmacology 2025 Feb 20;148:114141
Protective effect and mechanism of plant-derived Lactobacillus G11 on septic myocardial injury.
Zhang J, Tian Y, Yan H, Wu X, Deng C, Zhou Y, Liu J, Li X, Tian J, Bian Z, Yang Y, Chen Y
International immunopharmacology 2025 Feb 20;148:114021
International immunopharmacology 2025 Feb 20;148:114021
Ceria Nanoparticles Improve the Quality of Aging Oocytes in Mice by Enhancing ROS Scavenging Ability.
Wang Y, Zhong C, Ma X, Liu X, Zhang B, Min C, Zhang K, Wang X, Hou S, Zhao J, Wang J, Fang Y, Liu H, Ding H, Guo J, Cheng Y, Lu W
ACS applied bio materials 2025 Feb 17;8(2):992-1001
ACS applied bio materials 2025 Feb 17;8(2):992-1001
Spinal AT1R contributes to neuroinflammation and neuropathic pain via NOX2-dependent redox signaling in microglia.
Zhang W, Jiao B, Yu S, Zhang K, Sun J, Liu B, Zhang X
Free radical biology & medicine 2025 Feb 1;227:143-156
Free radical biology & medicine 2025 Feb 1;227:143-156
Phillyrin prevents calcium oxalate kidney stones through the PPARγ signaling pathway.
Chu X, Chang X, Liu S, Zhang S, Xie E, Zhou B
Renal failure 2025 Dec;47(1):2486559
Renal failure 2025 Dec;47(1):2486559
Gut microbiota-derived butyrate prevents aortic dissection via GPR41.
Yang HX, Wang BX, Dong XL, Sun J, Miao ZL, Pan LL
Acta pharmacologica Sinica 2025 Dec;46(12):3230-3243
Acta pharmacologica Sinica 2025 Dec;46(12):3230-3243
Norepinephrine promotes oxidative stress in vascular adventitial fibroblasts via PKC/NFκB-mediated NOX2 upregulation.
Wang YM, Dong HK, Dai M, Wang JX, Xu XY, Zhu GQ, Li XZ
Redox report : communications in free radical research 2025 Dec;30(1):2494314
Redox report : communications in free radical research 2025 Dec;30(1):2494314
Unveiling the role of Jagged2 in hypoxic pulmonary arterial hypertension: A NOX2-mediated pathway.
Yuan J, Chen Y, Wu S, Shi H, Dong Y, Han Y, Cui W
Journal of cell communication and signaling 2025 Dec;19(4):e70032
Journal of cell communication and signaling 2025 Dec;19(4):e70032
Inhibition of TRPC3-Nox2 Complex Formation Ameliorates Skeletal Muscle Atrophy.
Kato Y, Wu D, Ito T, Atef Y, Ayukawa K, Mi X, Nishiyama K, Nishimura A, Nishida M
Antioxidants (Basel, Switzerland) 2025 Dec 26;15(1)
Antioxidants (Basel, Switzerland) 2025 Dec 26;15(1)
Targeting NADPH oxidase 2 suppresses the growth of esophageal squamous cell carcinoma by regulating BTG2 pathway.
Liu XJ, Yang CL, Zhang YL, Huang JX
Discover oncology 2025 Dec 24;17(1):102
Discover oncology 2025 Dec 24;17(1):102
Targeting ER stress/ROS-driven VEGF signaling axis: AdipoRon as a multifunctional therapeutic agent for alkali burn-induced corneal neovascularization.
Wang C, Yuan K, Wu Y, Jiang T, Mou Y, Wang N, Chen X, Yu J, Yang S, Jin X
Free radical biology & medicine 2025 Dec 16;241:117-136
Free radical biology & medicine 2025 Dec 16;241:117-136
Cold exposure promotes the progression of osteoarthritis through downregulating APOE in cartilage.
Zhang Y, Fu M, Zhou C, Wang X, Jiang Z, Jiang C, Guo S, Pang Z, Wang C, Yu T, An S, Wang X, Wang Z
EMBO molecular medicine 2025 Aug;17(8):2137-2162
EMBO molecular medicine 2025 Aug;17(8):2137-2162
CYBB as a potential therapeutic target through influencing ferroptosis and macrophage in ovarian cancer.
Ye TY, Wu SF, Wang XY
Discover oncology 2025 Aug 9;16(1):1513
Discover oncology 2025 Aug 9;16(1):1513
Age-Related Mitochondrial Alterations Contribute to Myocardial Responses During Sepsis.
Du J, Yu Q, Anjorin OE, Wang M
Cells 2025 Aug 7;14(15)
Cells 2025 Aug 7;14(15)
Curcumin preserves bone health compromised by diabetes by inhibiting osteoporosis through regulation of the SIRT3/FoxO3a signalling pathway.
Mohammad OH, Yang S, Ji W, Ma H, Tao R
Scientific reports 2025 Aug 12;15(1):29566
Scientific reports 2025 Aug 12;15(1):29566
Obesity-induced activation of NADPH oxidase 2 prolongs cardiac repolarization via inhibiting K+ currents.
Li B, Chen Y, Zhao M, Chen Z, Lin Z, Liu J, Wang X, Zhang J, Li Y
PloS one 2024;19(12):e0316701
PloS one 2024;19(12):e0316701
Annao Pingchong decoction attenuates oxidative stress and neuronal apoptosis following intracerebral hemorrhage via RAGE-NOX2/4 axis.
Wang X, Lin X, Chen Z, Long H, Zhou X, Lei S, Liu J, Dong H, Liu F, Hu H, Guo C
Frontiers in neuroscience 2024;18:1491343
Frontiers in neuroscience 2024;18:1491343
Probucol mitigates high-fat diet-induced cognitive and social impairments by regulating brain redox and insulin resistance.
Wu HM, Yang YV, Huang NJ, Fan LP, Dai YY, Hu KT, Tang TY, Liu L, Xu Y, Liu DT, Cai ZX, Niu XY, Ren XY, Yao ZH, Qin HY, Chen JZ, Huang X, Zhang C, You X, Wang C, He Y, Hong W, Sun YX, Zhan YH, Lin SY
Frontiers in neuroscience 2024;18:1368552
Frontiers in neuroscience 2024;18:1368552
Reversal of cholestatic liver disease by the inhibition of sphingosine 1-phosphate receptor 2 signaling.
Cao H, Chen L, Zeng Z, Wu X, Lei Y, Jia W, Yue G, Yi B, Li YJ, Shi Y
PeerJ 2024;12:e16744
PeerJ 2024;12:e16744
NOX2 and NOX4 expression in monocytes and macrophages-extracellular vesicles in signalling and therapeutics.
Rathi D, Rossi C, Pospíšil P, Ramalingam Manoharan R, Talarico L, Magnani A, Prasad A
Frontiers in cell and developmental biology 2024;12:1342227
Frontiers in cell and developmental biology 2024;12:1342227
Targeting mitochondrial dysfunction in atopic dermatitis with trilinolein: A triacylglycerol from the medicinal plant Cannabis fructus.
Wang Y, Lu H, Cheng L, Guo W, Hu Y, Du X, Liu X, Xu M, Liu Y, Zhang Y, Xi R, Wang P, Liu X, Duan Y, Zhu J, Li F
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155856
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155856
Melatonin alleviates aging-related heart failure through melatonin receptor 1A/B knockout in mice.
Feng Z, Liu Y, Yang Y, Bai J, Lin QY, Xia YL, Xie Y
Heliyon 2024 Sep 30;10(18):e38098
Heliyon 2024 Sep 30;10(18):e38098
Dietary nitrate maintains homeostasis of oxidative stress and gut microbiota to promote flap survival in type 2 diabetes mellitus rats.
Niu Q, Li D, Guo W, Feng Z, Han Z, Yang Y
BMC endocrine disorders 2024 Sep 10;24(1):184
BMC endocrine disorders 2024 Sep 10;24(1):184
Activation of nuclear receptor pregnane-X-receptor protects against abdominal aortic aneurysm by inhibiting oxidative stress.
Shen Z, Wang J, Chen Y, Fang P, Yuan A, Chen AF, Yan X, Lyu Y, Pu J
Redox biology 2024 Nov;77:103397
Redox biology 2024 Nov;77:103397
GDF15 attenuates sepsis-induced myocardial dysfunction by inhibiting cardiomyocytes ferroptosis via the SOCS1/GPX4 signaling pathway.
Li X, Sun H, Zhang L, Liang H, Zhang B, Yang J, Peng X, Sun J, Zhou Y, Zhai M, Jiang L, Zhu H, Duan W
European journal of pharmacology 2024 Nov 5;982:176894
European journal of pharmacology 2024 Nov 5;982:176894
Inhibition of MST1 ameliorates neuronal apoptosis via GSK3β/β-TrCP/NRF2 pathway in spinal cord injury accompanied by diabetes.
Huang W, Wu D, Cai C, Yao H, Tian Z, Yang Y, Pang M, Rong L, Liu B
Redox biology 2024 May;71:103104
Redox biology 2024 May;71:103104
Food therapy of scutellarein ameliorates pirarubicin‑induced cardiotoxicity in rats by inhibiting apoptosis and ferroptosis through regulation of NOX2‑induced oxidative stress.
Lan Y, Tian F, Tang H, Pu P, He Q, Duan L
Molecular medicine reports 2024 May;29(5)
Molecular medicine reports 2024 May;29(5)
Caffeic acid phenethyl ester inhibits neuro-inflammation and oxidative stress following spinal cord injury by mitigating mitochondrial dysfunction via the SIRT1/PGC1α/DRP1 signaling pathway.
Zhang Y, Deng Q, Hong H, Qian Z, Wan B, Xia M
Journal of translational medicine 2024 Mar 25;22(1):304
Journal of translational medicine 2024 Mar 25;22(1):304
FGF21 Inhibits Hypoxia/Reoxygenation-induced Renal Tubular Epithelial Cell Injury by Regulating the PPARγ/NF-κB Signaling Pathway.
Li R, Liu X
Cell biochemistry and biophysics 2024 Jun;82(2):909-918
Cell biochemistry and biophysics 2024 Jun;82(2):909-918
Role of plasmacytoid dendritic cells in vascular dysfunction in mice with renovascular hypertension.
Srinivas B, Alluri K, Rhaleb NE, Belmadani S, Matrougui K
Heliyon 2024 Jun 15;10(11):e31799
Heliyon 2024 Jun 15;10(11):e31799
Intracellular and extracellular Cyclophilin a promote cardiac fibrosis through TGF-β signaling in response to angiotensin Ⅱ.
Cao M, Zhao Q, Xia H, Lyu S, Luo J, Fu K, Chen R, Yuan W
Biochemical pharmacology 2024 Jul;225:116271
Biochemical pharmacology 2024 Jul;225:116271
KLF6 silencing attenuates MCAO-induced brain injury and cognitive dysfunction via targeting ferroptosis and activating the Nrf2/HO-1 pathway.
Qian H, Zhou S, Qian R, Li Q, Zhang J, Ding Y, Wang C
Human & experimental toxicology 2024 Jan-Dec;43:9603271241304372
Human & experimental toxicology 2024 Jan-Dec;43:9603271241304372
Nicotinamide mononucleotide attenuates airway epithelial barrier dysfunction via inhibiting SIRT3 SUMOylation in asthma.
Liang J, Zhou C, Zhang C, Liang S, Zhou Z, Zhou Z, Wu C, Zhao H, Meng X, Zou F, Yu C, Cai S
International immunopharmacology 2024 Jan 25;127:111328
International immunopharmacology 2024 Jan 25;127:111328
METTL3 silencing inhibits ferroptosis to suppress ovarian fibrosis in PCOS by upregulating m6A modification of GPX4.
Shen C, Jiang Y, Lin J, Guo Q, Fang D
Journal of molecular histology 2024 Dec;55(6):1163-1175
Journal of molecular histology 2024 Dec;55(6):1163-1175
Alizarin attenuates oxidative stress-induced mitochondrial damage in vascular dementia rats by promoting TRPM2 ubiquitination and proteasomal degradation via Smurf2.
Pan GP, Liu YH, Qi MX, Guo YQ, Shao ZL, Liu HT, Qian YW, Guo S, Yin YL, Li P
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156119
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156119
Bone morphogenetic protein 4 inhibits corneal neovascularization by blocking NETs-induced disruption to corneal epithelial barrier.
Shen S, Nan W, Zhang W, Wu H, Zhang Y
International immunopharmacology 2024 Dec 5;142(Pt A):113023
International immunopharmacology 2024 Dec 5;142(Pt A):113023
Ruscogenin attenuates osteoarthritis by modulating oxidative stress-mediated macrophage reprogramming via directly targeting Sirt3.
Liu Y, Li W, Tang H, Yang Z, Wei M, Zhou W, Li Z, Huang W
International immunopharmacology 2024 Dec 25;143(Pt 1):113336
International immunopharmacology 2024 Dec 25;143(Pt 1):113336
Accumulation of Advanced Oxidation Protein Products Promotes Age-Related Decline of Type H Vessels in Bone.
Zhao K, Zhu GZ, Li HZ, Gao JW, Tu C, Wu DZ, Huang YS, Han D, Chen XY, Wu LY, Zhong ZM
The journals of gerontology. Series A, Biological sciences and medical sciences 2024 Dec 11;80(1)
The journals of gerontology. Series A, Biological sciences and medical sciences 2024 Dec 11;80(1)
Zinc promotes microbial p-coumaric acid production that protects against cholestatic liver injury.
Li D, Wan M, Xue L, Zhang Z, Qiu Y, Mei F, Tang N, Yu C, Yu Y, Chen T, Ding X, Yang Q, Liu Q, Gu P, Jia W, Chen Y, Chen P
Cell host & microbe 2024 Dec 11;32(12):2195-2211.e9
Cell host & microbe 2024 Dec 11;32(12):2195-2211.e9
EGFR-MEK1/2 cascade negatively regulates bactericidal function of bone marrow macrophages in mice with Staphylococcus aureus osteomyelitis.
Jin M, Wu X, Hu J, Chen Y, Yang B, Cheng C, Yang M, Zhang X
PLoS pathogens 2024 Aug;20(8):e1012437
PLoS pathogens 2024 Aug;20(8):e1012437
NADPH oxidase-dependent free radical generation and protein adduct formation in neutrophils.
Manoharan RR, Zachová K, Buzáš M, Pospíšil P, Křupka M, Prasad A
RSC advances 2024 Aug 5;14(34):24765-24780
RSC advances 2024 Aug 5;14(34):24765-24780
Quercetin Mitigates Lysophosphatidylcholine (LPC)-Induced Neutrophil Extracellular Traps (NETs) Formation through Inhibiting the P2X7R/P38MAPK/NOX2 Pathway.
Liu S, Wang Y, Ying L, Li H, Zhang K, Liang N, Luo G, Xiao L
International journal of molecular sciences 2024 Aug 30;25(17)
International journal of molecular sciences 2024 Aug 30;25(17)
Bioinformatic analysis reveals the relationship between macrophage infiltration and Cybb downregulation in hyperoxia-induced bronchopulmonary dysplasia.
He Y, Li D, Zhang M, Li F
Scientific reports 2024 Aug 29;14(1):20089
Scientific reports 2024 Aug 29;14(1):20089
Oxidative stress and regulation of adipogenic differentiation capacity by sirtuins in adipose stem cells derived from female patients of advancing age.
Bernhardt A, Jamil A, Morshed MT, Ponnath P, Gille V, Stephan N, Sauer H, Wartenberg M
Scientific reports 2024 Aug 27;14(1):19885
Scientific reports 2024 Aug 27;14(1):19885
IL-1β mediates Candida tropicalis-induced immunosuppressive function of MDSCs to foster colorectal cancer.
Zhang Z, Chen Y, Pan X, Li P, Ren Z, Wang X, Chen Y, Shen S, Wang T, Lin A
Cell communication and signaling : CCS 2024 Aug 21;22(1):408
Cell communication and signaling : CCS 2024 Aug 21;22(1):408
The antihypertensive effect of Alizarin is achieved by activating VEGFR2/eNOS pathway, attenuating oxidative stress-induced mitochondrial damage and premature senescence.
Qian YW, Guo YQ, Li YL, Wang Y, Guo S, Niu QQ, Zhu ML, Li P
Life sciences 2024 Aug 15;351:122862
Life sciences 2024 Aug 15;351:122862
Matrine Suppresses Arsenic-Induced Malignant Transformation of SV-HUC-1 Cells via NOX2.
Wang L, Qiu N, Tong S, Yu Y, Xi S, Wang F
International journal of molecular sciences 2024 Aug 15;25(16)
International journal of molecular sciences 2024 Aug 15;25(16)
Asprosin contributes to vascular remodeling in hypertensive rats via superoxide signaling.
Xu ZQ, Li XZ, Zhu R, Ge R, Wei H, Shi HW, Wang Z, Yang C, Yang YW, Lu XJ, Chen AD, Zhu GQ, Tan X
Journal of hypertension 2024 Aug 1;42(8):1427-1439
Journal of hypertension 2024 Aug 1;42(8):1427-1439
Atorvastatin combined with imipenem alleviates lung injury in sepsis by inhibiting neutrophil extracellular trap formation via the ERK/NOX2 signaling pathway.
Zhang Y, Wu D, Sun Q, Luo Z, Zhang Y, Wang B, Chen W
Free radical biology & medicine 2024 Aug 1;220:179-191
Free radical biology & medicine 2024 Aug 1;220:179-191
Mitochondrial complex I activity in microglia sustains neuroinflammation.
Peruzzotti-Jametti L, Willis CM, Krzak G, Hamel R, Pirvan L, Ionescu RB, Reisz JA, Prag HA, Garcia-Segura ME, Wu V, Xiang Y, Barlas B, Casey AM, van den Bosch AMR, Nicaise AM, Roth L, Bates GR, Huang H, Prasad P, Vincent AE, Frezza C, Viscomi C, Balmus G, Takats Z, Marioni JC, D'Alessandro A, Murphy MP, Mohorianu I, Pluchino S
Nature 2024 Apr;628(8006):195-203
Nature 2024 Apr;628(8006):195-203
CYBB-Mediated Ferroptosis Associated with Immunosuppression in Mycobacterium leprae-Infected Monocyte-Derived Macrophages.
Wang Z, Liu T, Wang Z, Mi Z, Zhang Y, Wang C, Sun L, Ma S, Xue X, Liu H, Zhang F
The Journal of investigative dermatology 2024 Apr;144(4):874-887.e2
The Journal of investigative dermatology 2024 Apr;144(4):874-887.e2
GKT137831 in combination with adipose-derived stem cells alleviates high glucose-induced inflammaging and improves diabetic wound healing.
Dong Y, Zhang Y, Li F, Tang B, Lv D, Wang H, Luo S
Journal of leukocyte biology 2024 Apr 29;115(5):882-892
Journal of leukocyte biology 2024 Apr 29;115(5):882-892
Sphingolipid biosynthesis is essential for metabolic rewiring during T(H)17 cell differentiation.
Abimannan T, Parthibane V, Le SH, Vijaykrishna N, Fox SD, Karim B, Kunduri G, Blankenberg D, Andresson T, Bamba T, Acharya U, Acharya JK
Science advances 2024 Apr 26;10(17):eadk1045
Science advances 2024 Apr 26;10(17):eadk1045
Esculin targets TLR4 to protect against LPS-induced septic cardiomyopathy.
Su Z, Gao M, Weng L, Xu T
International immunopharmacology 2024 Apr 20;131:111897
International immunopharmacology 2024 Apr 20;131:111897
Nox2 inhibition reduces trophoblast ferroptosis in preeclampsia via the STAT3/GPX4 pathway.
Xu X, Zhu M, Zu Y, Wang G, Li X, Yan J
Life sciences 2024 Apr 15;343:122555
Life sciences 2024 Apr 15;343:122555
Dapagliflozin ameliorates myocardial infarction injury through AMPKα-dependent regulation of oxidative stress and apoptosis.
Peng Y, Guo M, Luo M, Lv D, Liao K, Luo S, Zhang B
Heliyon 2024 Apr 15;10(7):e29160
Heliyon 2024 Apr 15;10(7):e29160
Antigen stasis and airway nitrosative stress in human primary ciliary dyskinesia.
Gaston B, Smith LA, Davis MD, Saunders J, Daniels I, Horani A, Brody SL, Giddings O, Zhao Y, Marozkina N
American journal of physiology. Lung cellular and molecular physiology 2024 Apr 1;326(4):L468-L476
American journal of physiology. Lung cellular and molecular physiology 2024 Apr 1;326(4):L468-L476
Adipocyte-Derived Exosomal NOX4-Mediated Oxidative Damage Induces Premature Placental Senescence in Obese Pregnancy.
Tao Y, Chen W, Xu H, Xu J, Yang H, Luo X, Chen M, He J, Bai Y, Qi H
International journal of nanomedicine 2023;18:4705-4726
International journal of nanomedicine 2023;18:4705-4726
Effects of liraglutide on astrocyte polarization and neuroinflammation in db/db mice: focus on iron overload and oxidative stress.
An JR, Liu JT, Gao XM, Wang QF, Sun GY, Su JN, Zhang C, Yu JX, Yang YF, Shi Y
Frontiers in cellular neuroscience 2023;17:1136070
Frontiers in cellular neuroscience 2023;17:1136070
Identification and validation of immune-associated NETosis subtypes and biomarkers in anti-neutrophil cytoplasmic antibody associated glomerulonephritis.
Tao M, He Y, Li L, Li Y, Liao W, Nie H, Gao P
Frontiers in immunology 2023;14:1177968
Frontiers in immunology 2023;14:1177968
FGL2 deficiency alleviates maternal inflammation-induced blood-brain barrier damage by blocking PI3K/NF-κB mediated endothelial oxidative stress.
Huang L, Zhan D, Xing Y, Yan Y, Li Q, Zhang J, Li S, Ning Q, Zhang C, Luo X
Frontiers in immunology 2023;14:1157027
Frontiers in immunology 2023;14:1157027
Oscillatory shear stress promotes vein graft intimal hyperplasia via NADPH oxidase-related pathways.
Yao G, Li H, Zuo X, Wang C, Xiao Y, Zhao Y, Wang X
Frontiers in surgery 2023;10:1073557
Frontiers in surgery 2023;10:1073557
Pure total flavonoids from citrus alleviate oxidative stress and inflammation in nonalcoholic fatty liver disease by regulating the miR-137-3p/NOXA2/NOX2 pathway.
Yan JB, Nie YM, Xu SM, Zhang S, Chen ZY
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154944
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154944
A Novel NOX Inhibitor Alleviates Parkinson's Disease Pathology in PFF-Injected Mice.
Ofori K, Ghosh A, Verma DK, Wheeler D, Cabrera G, Seo JB, Kim YH
International journal of molecular sciences 2023 Sep 19;24(18)
International journal of molecular sciences 2023 Sep 19;24(18)
Inhibition of AT1R/IP3/IP3R-mediated Ca(2+) release protects against calcium oxalate crystals-induced renal oxidative stress.
Hong SY, Yang YY, Wang SG, Qin BL
Chemico-biological interactions 2023 Sep 1;382:110636
Chemico-biological interactions 2023 Sep 1;382:110636
Niclosamide Inhibits Aortic Valve Interstitial Cell Calcification by Interfering with the GSK-3β/β-Catenin Signaling Pathway.
Adhikari R, Shiwakoti S, Kim E, Choi IJ, Park SH, Ko JY, Chang K, Oak MH
Biomolecules & therapeutics 2023 Sep 1;31(5):515-525
Biomolecules & therapeutics 2023 Sep 1;31(5):515-525
Transient receptor potential vanilloid 4 (TRPV4) in neutrophils enhances myocardial ischemia/reperfusion injury.
Wu Y, Lu K, Lu Y, Liao J, Zhang S, Yang S, Zhao N, Dong Q, Chen L, Wu Q, Du Y
Journal of leukocyte biology 2023 Sep 1;114(3):266-279
Journal of leukocyte biology 2023 Sep 1;114(3):266-279
Glucocorticoid-induced activation of NOX/ROS/NF-κB signaling in MSCs contributes to the development of GONFH.
Xu H, Zeng Q, Zou K, Huang H, Chen J, Wang P, Yuan W, Xiao L, Tong P, Jin H
Apoptosis : an international journal on programmed cell death 2023 Oct;28(9-10):1332-1345
Apoptosis : an international journal on programmed cell death 2023 Oct;28(9-10):1332-1345
Intermittent fasting alleviates type 1 diabetes-induced cognitive dysfunction by improving the frontal cortical metabolic disorder.
Xiong F, Jiang K, Wu Y, Lou C, Ding C, Zhang W, Zhang X, Li C, Zheng H, Gao H
Biochimica et biophysica acta. Molecular basis of disease 2023 Oct;1869(7):166725
Biochimica et biophysica acta. Molecular basis of disease 2023 Oct;1869(7):166725
The novel peptide athycaltide-1 attenuates Ang II-induced pathological myocardial hypertrophy by reducing ROS and inhibiting the activation of CaMKII and ERK1/2.
Zheng X, Su F, Lei M, Li J, Zhang C, Zhang Y, Wei M, Li W, Chen S, Liu Y, Gao Q, Hao L
European journal of pharmacology 2023 Oct 15;957:175969
European journal of pharmacology 2023 Oct 15;957:175969
Colchicine protects against the development of experimental abdominal aortic aneurysm.
Zhao Y, Shen QR, Chen YX, Shi Y, Wu WB, Li Q, Li DJ, Shen FM, Fu H
Clinical science (London, England : 1979) 2023 Oct 11;137(19):1533-1545
Clinical science (London, England : 1979) 2023 Oct 11;137(19):1533-1545
Short-chain acyl-CoA dehydrogenase is a potential target for the treatment of vascular remodelling.
Zhong X, Li Z, Xu Q, Peng H, Su Y, Le K, Shu Z, Liao Y, Ma Z, Pan X, Xu S, Zhou S
Journal of hypertension 2023 May 1;41(5):775-793
Journal of hypertension 2023 May 1;41(5):775-793
Electroacupuncture alleviates early brain injury via modulating microglia polarization and suppressing neuroinflammation in a rat model of subarachnoid hemorrhage.
Wang Y, Yang X, Cao Y, Li X, Xu R, Yan J, Guo Z, Sun S, Sun X, Wu Y
Heliyon 2023 Mar;9(3):e14475
Heliyon 2023 Mar;9(3):e14475
Lnc-17Rik promotes the immunosuppressive function of Myeloid-Derived suppressive cells in esophageal cancer.
Wen J, Xuan B, Gao Y, Liu Y, Wang L, He L, Meng X, Zhou T, Tao Y, Guo K, Wang Y
Cellular immunology 2023 Mar;385:104676
Cellular immunology 2023 Mar;385:104676
Dioscin ameliorates silica-aggravated systemic lupus erythematosus via suppressing apoptosis and improving LC3-associated phagocytosis in MRL/lpr mice.
Zhang P, Lei X, Ou L, Cheng Y, Miao Q, Li C, Chen Y
International immunopharmacology 2023 Mar;116:109814
International immunopharmacology 2023 Mar;116:109814
Capsaicin inhibits aortic valvular interstitial cell calcification via the redox-sensitive NFκB/AKT/ERK1/2 pathway.
Adhikari R, Jung J, Shiwakoti S, Park EY, Kim HJ, Ko JY, You J, Lee M, Oak MH
Biochemical pharmacology 2023 Jun;212:115530
Biochemical pharmacology 2023 Jun;212:115530
Synergistic effect of elevated glucose levels with SARS-CoV-2 spike protein induced NOX-dependent ROS production in endothelial cells.
Zhang J, He L, Huang R, Alvarez JF, Yang DH, Sun Q, Wang F, Peng Z, Jiang N, Su L
Molecular biology reports 2023 Jul;50(7):6039-6047
Molecular biology reports 2023 Jul;50(7):6039-6047
The pro-inflammatory signature of lipopolysaccharide in spontaneous contracting embryoid bodies differentiated from mouse embryonic stem cells.
Scharmacher J, Wartenberg M, Sauer H
Journal of cellular and molecular medicine 2023 Jul;27(14):2045-2058
Journal of cellular and molecular medicine 2023 Jul;27(14):2045-2058
Contemporary Antiretroviral Therapy Dysregulates Iron Transport and Augments Mitochondrial Dysfunction in HIV-Infected Human Microglia and Neural-Lineage Cells.
Kaur H, Minchella P, Alvarez-Carbonell D, Purandare N, Nagampalli VK, Blankenberg D, Hulgan T, Gerschenson M, Karn J, Aras S, Kallianpur AR
International journal of molecular sciences 2023 Jul 31;24(15)
International journal of molecular sciences 2023 Jul 31;24(15)
Dysregulated B7H4/JAK2/STAT3 Pathway Involves in Hypertriglyceridemia Acute Pancreatitis and Is Attenuated by Baicalin.
Yang J, Han F, Wu G, Dong Y, Su H, Xu J, Li J
Digestive diseases and sciences 2023 Feb;68(2):478-486
Digestive diseases and sciences 2023 Feb;68(2):478-486
Stromal Vascular Fraction Restores Vasodilatory Function by Reducing Oxidative Stress in Aging-Induced Coronary Microvascular Disease.
Tracy EP, Dukes M, Rowe G, Beare JE, Nair R, LeBlanc AJ
Antioxidants & redox signaling 2023 Feb;38(4-6):261-281
Antioxidants & redox signaling 2023 Feb;38(4-6):261-281
Saxagliptin alleviates erectile dysfunction through increasing stromal cell-derived factor-1 in diabetes mellitus.
Sun T, Xu W, Wang J, Wang T, Wang S, Liu K, Liu J
Andrology 2023 Feb;11(2):295-306
Andrology 2023 Feb;11(2):295-306
Acid sphingomyelinase promotes diabetic cardiomyopathy via NADPH oxidase 4 mediated apoptosis.
Liu R, Duan T, Yu L, Tang Y, Liu S, Wang C, Fang WJ
Cardiovascular diabetology 2023 Feb 2;22(1):25
Cardiovascular diabetology 2023 Feb 2;22(1):25
Adrenomedullin Improves Hypertension and Vascular Remodeling partly through the Receptor-Mediated AMPK Pathway in Rats with Obesity-Related Hypertension.
Wang HY, Wang FZ, Chang R, Wang Q, Liu SY, Cheng ZX, Gao Q, Zhou H, Zhou YB
International journal of molecular sciences 2023 Feb 15;24(4)
International journal of molecular sciences 2023 Feb 15;24(4)
Exosomal RBP4 potentiated hepatic lipid accumulation and inflammation in high-fat-diet-fed mice by promoting M1 polarization of Kupffer cells.
Yao JM, Ying HZ, Zhang HH, Qiu FS, Wu JQ, Yu CH
Free radical biology & medicine 2023 Feb 1;195:58-73
Free radical biology & medicine 2023 Feb 1;195:58-73
Apolipoprotein C-III itself stimulates the Syk/cPLA2-induced inflammasome activation of macrophage to boost anti-tumor activity of CD8(+) T cell.
Hu X, Ding S, Lu G, Lin Z, Liao L, Xiao W, Ding Y, Zhang Y, Wang Z, Gong W, Jia X
Cancer immunology, immunotherapy : CII 2023 Dec;72(12):4123-4144
Cancer immunology, immunotherapy : CII 2023 Dec;72(12):4123-4144
Nogo-B mediates endothelial oxidative stress and inflammation to promote coronary atherosclerosis in pressure-overloaded mouse hearts.
Zhang Y, Li JJ, Xu R, Wang XP, Zhao XY, Fang Y, Chen YP, Ma S, Di XH, Wu W, She G, Pang ZD, Wang YD, Zhang X, Xie W, Deng XL, Du XJ, Zhang Y
Redox biology 2023 Dec;68:102944
Redox biology 2023 Dec;68:102944
Comprehensive analysis and identification of prognostic biomarkers and immunotherapeutic targets in the NADPH oxidase family (and its regulatory subunits) in pancreatic ductal adenocarcinoma.
Guo R, Zheng P, Zhu S, Zeng Z, Li Z, Yang Y
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2023 Dec;25(12):3460-3470
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2023 Dec;25(12):3460-3470
BMP4 inhibits corneal neovascularization by interfering with tip cells in angiogenesis.
Nan W, He Y, Shen S, Wu M, Wang S, Zhang Y
Experimental eye research 2023 Dec;237:109680
Experimental eye research 2023 Dec;237:109680
Fibroblast growth factor 21 protects the liver from apoptosis in a type 1 diabetes mouse model via regulating L-lactate homeostasis.
Yan J, Xie J, Xu S, Guo Y, Ji K, Li C, Gao H, Zhao L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115737
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115737
Purinergic receptor P2X7 activates NOX2/JNK signaling to participate in granulosa cell inflammation and apoptosis in polycystic ovary syndrome.
Shen C, Jiang Y, Lin J, He Y, Liu Y, Fang D
Journal of bioenergetics and biomembranes 2023 Aug;55(4):313-322
Journal of bioenergetics and biomembranes 2023 Aug;55(4):313-322
Angiotensin II Increases Oxidative Stress and Inflammation in Female, But Not Male, Endothelial Cells.
Weber CM, Harris MN, Zic SM, Sangha GS, Arnold NS, Dluzen DF, Clyne AM
Cellular and molecular bioengineering 2023 Apr;16(2):127-141
Cellular and molecular bioengineering 2023 Apr;16(2):127-141
SGLT2 inhibition ameliorates nano plastics-induced premature endothelial senescence and dysfunction.
Dhakal B, Shiwakoti S, Park EY, Kang KW, Schini-Kerth VB, Park SH, Ji HY, Park JS, Ko JY, Oak MH
Scientific reports 2023 Apr 17;13(1):6256
Scientific reports 2023 Apr 17;13(1):6256
Aerobic Exercise Training Improves Renal Injury in Spontaneously Hypertensive Rats by Increasing Renalase Expression in Medulla.
Luo M, Cao S, Lv D, He L, He Z, Li L, Li Y, Luo S, Chang Q
Frontiers in cardiovascular medicine 2022;9:922705
Frontiers in cardiovascular medicine 2022;9:922705
Lonicera caerulea Berry Polyphenols Extract Alleviates Exercise Fatigue in Mice by Reducing Oxidative Stress, Inflammation, Skeletal Muscle Cell Apoptosis, and by Increasing Cell Proliferation.
Liu S, Meng F, Zhang D, Shi D, Zhou J, Guo S, Chang X
Frontiers in nutrition 2022;9:853225
Frontiers in nutrition 2022;9:853225
Recurrent Hypoglycemia Impaired Vascular Function in Advanced T2DM Rats by Inducing Pyroptosis.
Luo M, Hu Y, Lv D, Xie L, Yang S, Zuo D, Xue Y, He A
Oxidative medicine and cellular longevity 2022;2022:7812407
Oxidative medicine and cellular longevity 2022;2022:7812407
Schisandrin B Diet Inhibits Oxidative Stress to Reduce Ferroptosis and Lipid Peroxidation to Prevent Pirarubicin-Induced Hepatotoxicity.
Shi H, Yan Y, Yang H, Pu P, Tang H
BioMed research international 2022;2022:5623555
BioMed research international 2022;2022:5623555
Angiotensin II Induces Cardiac Edema and Hypertrophic Remodeling through Lymphatic-Dependent Mechanisms.
Bai J, Yin L, Yu WJ, Zhang YL, Lin QY, Li HH
Oxidative medicine and cellular longevity 2022;2022:5044046
Oxidative medicine and cellular longevity 2022;2022:5044046
Soluble Epoxide Hydrolase Inhibition Protected against Diabetic Cardiomyopathy through Inducing Autophagy and Reducing Apoptosis Relying on Nrf2 Upregulation and Transcription Activation.
Fang Q, Liu X, Ding J, Zhang Z, Chen G, Du T, Wang Y, Xu R
Oxidative medicine and cellular longevity 2022;2022:3773415
Oxidative medicine and cellular longevity 2022;2022:3773415
Change in Oxidative Stress and Mitochondrial Dynamics in Response to Elevated Cold-Inducible RNA-Binding Protein in Cardiac Surgery-Associated Acute Kidney Injury.
Zheng X, Fan Y, Li J, Ma T, Li Y, Wang Q, Yan Y, Liu W
Oxidative medicine and cellular longevity 2022;2022:3576892
Oxidative medicine and cellular longevity 2022;2022:3576892
Pyrrosia petiolosa Extract Ameliorates Ethylene Glycol-Induced Urolithiasis in Rats by Inhibiting Oxidative Stress and Inflammatory Response.
Zhou F, Wang X
Disease markers 2022;2022:1913067
Disease markers 2022;2022:1913067
Rosmarinic Acid Ameliorates Pulmonary Ischemia/Reperfusion Injury by Activating the PI3K/Akt Signaling Pathway.
Luo W, Tao Y, Chen S, Luo H, Li X, Qu S, Chen K, Zeng C
Frontiers in pharmacology 2022;13:860944
Frontiers in pharmacology 2022;13:860944
A Novel Compound, Tanshinol Borneol Ester, Ameliorates Pressure Overload-Induced Cardiac Hypertrophy by Inhibiting Oxidative Stress via the mTOR/β-TrCP/NRF2 Pathway.
Han D, Wang F, Wang B, Qiao Z, Cui X, Zhang Y, Jiang Q, Liu M, Shangguan J, Zheng X, Bai Y, Du C, Shen D
Frontiers in pharmacology 2022;13:830763
Frontiers in pharmacology 2022;13:830763
Administration of USP7 inhibitor P22077 inhibited cardiac hypertrophy and remodeling in Ang II-induced hypertensive mice.
Gu YH, Ren KW, Wang Y, Wang SH, Yu XH, Xu LW, Li HH, Bi HL
Frontiers in pharmacology 2022;13:1021361
Frontiers in pharmacology 2022;13:1021361
Interleukin 32 participates in cardiomyocyte-induced oxidative stress, inflammation and apoptosis during hypoxia/reoxygenation via the NOD2/NOX2/MAPK signaling pathway.
Li Y, Wang Z
Experimental and therapeutic medicine 2022 Sep;24(3):567
Experimental and therapeutic medicine 2022 Sep;24(3):567
A dual Keap1 and p47(phox) inhibitor Ginsenoside Rb1 ameliorates high glucose/ox-LDL-induced endothelial cell injury and atherosclerosis.
Wang ZC, Niu KM, Wu YJ, Du KR, Qi LW, Zhou YB, Sun HJ
Cell death & disease 2022 Sep 26;13(9):824
Cell death & disease 2022 Sep 26;13(9):824
Combination Treatment with Hydroxytyrosol and Vitamin E Improves NAFLD-Related Fibrosis.
Panera N, Braghini MR, Crudele A, Smeriglio A, Bianchi M, Condorelli AG, Nobili R, Conti LA, De Stefanis C, Lioci G, Gurrado F, Comparcola D, Mosca A, Sartorelli MR, Scoppola V, Svegliati-Baroni G, Trombetta D, Alisi A
Nutrients 2022 Sep 14;14(18)
Nutrients 2022 Sep 14;14(18)
Edaravone dexborneol protects cerebral ischemia reperfusion injury through activating Nrf2/HO-1 signaling pathway in mice.
Xu L, Gao Y, Hu M, Dong Y, Xu J, Zhang J, Lv P
Fundamental & clinical pharmacology 2022 Oct;36(5):790-800
Fundamental & clinical pharmacology 2022 Oct;36(5):790-800
Inhibition of Hypoxia-Inducible Factor Prolyl-Hydroxylase Modulates Platelet Function.
Gu W, Qi J, Zhang S, Ding Y, Qiao J, Han Y
Thrombosis and haemostasis 2022 Oct;122(10):1693-1705
Thrombosis and haemostasis 2022 Oct;122(10):1693-1705
Suramin enhances chondrogenic properties by regulating the p67(phox)/PI3K/AKT/SOX9 signalling pathway.
Liu ZM, Shen PC, Lu CC, Chou SH, Tien YC
Bone & joint research 2022 Oct;11(10):723-738
Bone & joint research 2022 Oct;11(10):723-738
Mycobacterium tuberculosis Utilizes Host Histamine Receptor H1 to Modulate Reactive Oxygen Species Production and Phagosome Maturation via the p38MAPK-NOX2 Axis.
Mo S, Guo J, Ye T, Zhang X, Zeng J, Xu Y, Peng B, Dai Y, Xiao W, Zhang P, Deng G, Xu D, Long X, Cai Y, Chen X
mBio 2022 Oct 26;13(5):e0200422
mBio 2022 Oct 26;13(5):e0200422
Identification of a necroptosis-related prognostic gene signature associated with tumor immune microenvironment in cervical carcinoma and experimental verification.
Sun K, Huang C, Li JZ, Luo ZX
World journal of surgical oncology 2022 Oct 17;20(1):342
World journal of surgical oncology 2022 Oct 17;20(1):342
Gut microbiome dysbiosis contributes to abdominal aortic aneurysm by promoting neutrophil extracellular trap formation.
Tian Z, Zhang Y, Zheng Z, Zhang M, Zhang T, Jin J, Zhang X, Yao G, Kong D, Zhang C, Wang Z, Zhang Q
Cell host & microbe 2022 Oct 12;30(10):1450-1463.e8
Cell host & microbe 2022 Oct 12;30(10):1450-1463.e8
The Clostridium Metabolite P-Cresol Sulfate Relieves Inflammation of Primary Biliary Cholangitis by Regulating Kupffer Cells.
Fu HY, Xu JM, Ai X, Dang FT, Tan X, Yu HY, Feng J, Yang WX, Ma HT, Tu RF, Gupta AK, Manandhar LK, Bao WM, Tang YM
Cells 2022 Nov 26;11(23)
Cells 2022 Nov 26;11(23)
Lipopolysaccharide induces placental mitochondrial dysfunction in murine and human systems by reducing MNRR1 levels via a TLR4-independent pathway.
Purandare N, Kunji Y, Xi Y, Romero R, Gomez-Lopez N, Fribley A, Grossman LI, Aras S
iScience 2022 Nov 18;25(11):105342
iScience 2022 Nov 18;25(11):105342
Graphene oxide leads to mitochondrial-dependent apoptosis by activating ROS-p53-mPTP pathway in intestinal cells.
Feng W, Wang J, Li B, Liu Y, Xu D, Cheng K, Zhuang J
The international journal of biochemistry & cell biology 2022 May;146:106206
The international journal of biochemistry & cell biology 2022 May;146:106206
Impact of Selective Renal Afferent Denervation on Oxidative Stress and Vascular Remodeling in Spontaneously Hypertensive Rats.
Wu LL, Zhang Y, Li XZ, Du XL, Gao Y, Wang JX, Wang XL, Chen Q, Li YH, Zhu GQ, Tan X
Antioxidants (Basel, Switzerland) 2022 May 20;11(5)
Antioxidants (Basel, Switzerland) 2022 May 20;11(5)
Pu-erh Tea Restored Circadian Rhythm Disruption by Regulating Tryptophan Metabolism.
Hu S, Luo L, Bian X, Liu RH, Zhao S, Chen Y, Sun K, Jiang J, Liu Z, Zeng L
Journal of agricultural and food chemistry 2022 May 11;70(18):5610-5623
Journal of agricultural and food chemistry 2022 May 11;70(18):5610-5623
Prednisone Ameliorates Atrial Inflammation and Fibrosis in Atrial Tachypacing Dogs.
Zhang H, Lai Y, Zhou H, Zou L, Xu Y, Yin Y
International heart journal 2022 Mar 30;63(2):347-355
International heart journal 2022 Mar 30;63(2):347-355
Effects of polystyrene nanoplastics on endothelium senescence and its underlying mechanism.
Shiwakoti S, Ko JY, Gong D, Dhakal B, Lee JH, Adhikari R, Gwak Y, Park SH, Jun Choi I, Schini-Kerth VB, Kang KW, Oak MH
Environment international 2022 Jun;164:107248
Environment international 2022 Jun;164:107248
Disruption of mitochondrial redox homeostasis as a mechanism of antimony-induced reactive oxygen species and cytotoxicity.
Su L, Fang W, Zhao X, Zhu L, Gao L, Chen G
Ecotoxicology and environmental safety 2022 Jun 1;237:113519
Ecotoxicology and environmental safety 2022 Jun 1;237:113519
In utero hypoxia attenuated acetylcholine-mediated vasodilatation via CHRM3/p-NOS3 in fetal sheep MCA: role of ROS/ERK1/2.
He Y, Su H, Li N, Zhang Y, Zhang P, Zhang Y, Ye Y, Zhang Y, Tang J, Xu Z
Hypertension research : official journal of the Japanese Society of Hypertension 2022 Jul;45(7):1168-1182
Hypertension research : official journal of the Japanese Society of Hypertension 2022 Jul;45(7):1168-1182
Accumulation of advanced oxidation protein products contributes to age-related impairment of gap junction intercellular communication in osteocytes of male mice.
Tu C, Lai S, Huang Z, Cai G, Zhao K, Gao J, Wu Z, Zhong Z
Bone & joint research 2022 Jul;11(7):413-425
Bone & joint research 2022 Jul;11(7):413-425
Role of Nox4 in High Calcium-Induced Renal Oxidative Stress Damage and Crystal Deposition.
Xun Y, Zhou P, Yang Y, Li C, Zhang J, Hu H, Qin B, Zhang Z, Wang Q, Lu Y, Wang S
Antioxidants & redox signaling 2022 Jan;36(1-3):15-38
Antioxidants & redox signaling 2022 Jan;36(1-3):15-38
Reducing oxidative stress may be important for treating pirarubicin-induced cardiotoxicity with schisandrin B.
Tang H, Zhao J, Feng R, Pu P, Wen L
Experimental and therapeutic medicine 2022 Jan;23(1):68
Experimental and therapeutic medicine 2022 Jan;23(1):68
mTORC1 activation induced proximal tubular damage via the pentose phosphate pathway in lupus nephritis.
Mao Z, Tan Y, Tao J, Li L, Yu F, Zhao M
Free radical biology & medicine 2022 Aug 20;189:91-101
Free radical biology & medicine 2022 Aug 20;189:91-101
Chronic Sigma 1 receptor activation alleviates right ventricular dysfunction secondary to pulmonary arterial hypertension.
Sun Y, Wan W, Zhao X, Han X, Ye T, Chen X, Ran Q, Wang X, Liu X, Qu C, Shi S, Zhang C, Yang B
Bioengineered 2022 Apr;13(4):10843-10856
Bioengineered 2022 Apr;13(4):10843-10856
Honokiol improves endothelial function in type 2 diabetic rats via alleviating oxidative stress and insulin resistance.
He A, Yu H, Hu Y, Chen H, Li X, Shen J, Zhuang R, Chen Y, Sasmita BR, Luo M, Lv D
Biochemical and biophysical research communications 2022 Apr 16;600:109-116
Biochemical and biophysical research communications 2022 Apr 16;600:109-116
A Novel NOX Inhibitor Treatment Attenuates Parkinson's Disease-Related Pathology in Mouse Models.
Ghosh AA, Verma DK, Cabrera G, Ofori K, Hernandez-Quijada K, Kim JK, Chung JH, Moore M, Moon SH, Seo JB, Kim YH
International journal of molecular sciences 2022 Apr 12;23(8)
International journal of molecular sciences 2022 Apr 12;23(8)
Electronic cigarette exposure causes vascular endothelial dysfunction due to NADPH oxidase activation and eNOS uncoupling.
El-Mahdy MA, Ewees MG, Eid MS, Mahgoup EM, Khaleel SA, Zweier JL
American journal of physiology. Heart and circulatory physiology 2022 Apr 1;322(4):H549-H567
American journal of physiology. Heart and circulatory physiology 2022 Apr 1;322(4):H549-H567
Crocin Improves Endothelial Mitochondrial Dysfunction via GPx1/ROS/KCa3.1 Signal Axis in Diabetes.
Li X, Liu Y, Cao A, Li C, Wang L, Wu Q, Li X, Lv X, Zhu J, Chun H, Laba C, Du X, Zhang Y, Yang H
Frontiers in cell and developmental biology 2021;9:651434
Frontiers in cell and developmental biology 2021;9:651434
Human Tissue Kallikrein 1 Is Downregulated in Elderly Human Prostates and Possesses Potential In Vitro Antioxidative and Antifibrotic Effects in Rodent Prostates.
Zhang M, Luo C, Lin D, Cui K, Chen Z, Liu J
Oxidative medicine and cellular longevity 2021;2021:8877540
Oxidative medicine and cellular longevity 2021;2021:8877540
Shenxian-Shengmai Oral Liquid Improves Sinoatrial Node Dysfunction through the PKC/NOX-2 Signaling Pathway.
Zhang H, Hao M, Li L, Chen K, Qi J, Chen W, Cai X, Chen C, Liu Z, Hou P
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5572140
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5572140
Microglia-Derived Exosomes Improve Spinal Cord Functional Recovery after Injury via Inhibiting Oxidative Stress and Promoting the Survival and Function of Endothelia Cells.
Peng W, Wan L, Luo Z, Xie Y, Liu Y, Huang T, Lu H, Hu J
Oxidative medicine and cellular longevity 2021;2021:1695087
Oxidative medicine and cellular longevity 2021;2021:1695087
17β-Estradiol promotes LC3B-associated phagocytosis in trained immunity of female mice against sepsis.
Sun Z, Qu J, Xia X, Pan Y, Liu X, Liang H, Dou H, Hou Y
International journal of biological sciences 2021;17(2):460-474
International journal of biological sciences 2021;17(2):460-474
Iron Oxide Nanoparticles Combined with Cytosine Arabinoside Show Anti-Leukemia Stem Cell Effects on Acute Myeloid Leukemia by Regulating Reactive Oxygen Species.
Dou J, Li L, Guo M, Mei F, Zheng D, Xu H, Xue R, Bao X, Zhao F, Zhang Y
International journal of nanomedicine 2021;16:1231-1244
International journal of nanomedicine 2021;16:1231-1244
Nox2 contributes to reactive oxygen species-induced redox imbalance in cancer-induced bone pain.
Xu BY, Sun J, Chen SP, Wang XM, Chen N, Li DY, Chen G, Mei W, Tian YK, Zhou YQ, Ye DW
American journal of translational research 2021;13(3):1269-1279
American journal of translational research 2021;13(3):1269-1279
Nox2 impairs VEGF-A-induced angiogenesis in placenta via mitochondrial ROS-STAT3 pathway.
Hu C, Wu Z, Huang Z, Hao X, Wang S, Deng J, Yin Y, Tan C
Redox biology 2021 Sep;45:102051
Redox biology 2021 Sep;45:102051
Compound essential oils relieve oxidative stress caused by PM(2) (.5) exposure by inhibiting autophagy through the AMPK/mTOR pathway.
Ren F, Xu X, Xu J, Mei Y, Zhang J, Wang X, Li F
Environmental toxicology 2021 Sep;36(9):1765-1774
Environmental toxicology 2021 Sep;36(9):1765-1774
Effects of different intensities of continuous training on vascular inflammation and oxidative stress in spontaneously hypertensive rats.
Luo M, Cao C, Niebauer J, Yan J, Ma X, Chang Q, Zhang T, Huang X, Liu G
Journal of cellular and molecular medicine 2021 Sep;25(17):8522-8536
Journal of cellular and molecular medicine 2021 Sep;25(17):8522-8536
Aged Ripe Pu-erh Tea Reduced Oxidative Stress-Mediated Inflammation in Dextran Sulfate Sodium-Induced Colitis Mice by Regulating Intestinal Microbes.
Hu S, Li S, Liu Y, Sun K, Luo L, Zeng L
Journal of agricultural and food chemistry 2021 Sep 15;69(36):10592-10605
Journal of agricultural and food chemistry 2021 Sep 15;69(36):10592-10605
Canagliflozin is a potential cardioprotective drug but exerts no significant effects on pirarubicin‑induced cardiotoxicity in rats.
Shi H, Zeng Q, Wei Y, Yang H, Tang H, Wang D, Pu P, Feng R
Molecular medicine reports 2021 Oct;24(4)
Molecular medicine reports 2021 Oct;24(4)
The protective effect of harpagoside on angiotensin II (Ang II)-induced blood-brain barrier leakage in vitro.
Lu YW, Hao RJ, Wei YY, Yu GR
Phytotherapy research : PTR 2021 Nov;35(11):6241-6254
Phytotherapy research : PTR 2021 Nov;35(11):6241-6254
Distinction between 2'- and 3'-Phosphate Isomers of a Fluorescent NADPH Analogue Led to Strong Inhibition of Cancer Cells Migration.
Manuel R, Lima MS, Dilly S, Daunay S, Abbe P, Pramil E, Solier S, Guillaumond F, Tubiana SS, Escargueil A, Pêgas Henriques JA, Ferrand N, Erdelmeier I, Boucher JL, Bertho G, Agranat I, Rocchi S, Sabbah M, Slama Schwok A
Antioxidants (Basel, Switzerland) 2021 May 4;10(5)
Antioxidants (Basel, Switzerland) 2021 May 4;10(5)
Mild hypothermia in rat with acute myocardial ischaemia-reperfusion injury complicating severe sepsis.
Qin Z, Shen S, Qu K, Nie Y, Zhang H
Journal of cellular and molecular medicine 2021 May 31;25(13):6448-54
Journal of cellular and molecular medicine 2021 May 31;25(13):6448-54
Protective effect of recombinant Lactobacillus plantarum against H(2)O(2)-induced oxidative stress in HUVEC cells.
Wang G, Hao M, Liu Q, Jiang Y, Huang H, Yang G, Wang C
Journal of Zhejiang University. Science. B 2021 May 15;22(5):348-365
Journal of Zhejiang University. Science. B 2021 May 15;22(5):348-365
C-C motif ligand 8 promotes atherosclerosis via NADPH oxidase 2/reactive oxygen species-induced endothelial permeability increase.
Xue S, Tang H, Zhao G, Fang C, Shen Y, Yan D, Yuan Y, Fu W, Shi Z, Tang X, Guo D
Free radical biology & medicine 2021 May 1;167:181-192
Free radical biology & medicine 2021 May 1;167:181-192
Sirtuin 1 ameliorates defenestration in hepatic sinusoidal endothelial cells during liver fibrosis via inhibiting stress-induced premature senescence.
Luo X, Bai Y, He S, Sun S, Jiang X, Yang Z, Lu D, Wei P, Liang Y, Peng C, Wang Y, Sheng R, Han S, Li X, Zhang B
Cell proliferation 2021 Mar;54(3):e12991
Cell proliferation 2021 Mar;54(3):e12991
Scoparone alleviates Ang II-induced pathological myocardial hypertrophy in mice by inhibiting oxidative stress.
Lyu L, Chen J, Wang W, Yan T, Lin J, Gao H, Li H, Lv R, Xu F, Fang L, Chen Y
Journal of cellular and molecular medicine 2021 Mar;25(6):3136-3148
Journal of cellular and molecular medicine 2021 Mar;25(6):3136-3148
Hsa_circ_0005915 promotes N,N-dimethylformamide-induced oxidative stress in HL-7702 cells through NRF2/ARE axis.
Liu Z, He Q, Liu Y, Zhang Y, Cui M, Peng H, Wang Y, Chen S, Li D, Chen L, Xiao Y, Chen W, Wang Q
Toxicology 2021 Jun 30;458:152838
Toxicology 2021 Jun 30;458:152838
Protective effect of scorpion venom heat-resistant synthetic peptide against PM(2.5)-induced microglial polarization via TLR4-mediated autophagy activating PI3K/AKT/NF-κB signaling pathway.
Xu X, Xu H, Ren F, Huang L, Xu J, Li F
Journal of neuroimmunology 2021 Jun 15;355:577567
Journal of neuroimmunology 2021 Jun 15;355:577567
Silencing COX-2 blocks PDK1/TRAF4-induced AKT activation to inhibit fibrogenesis during skeletal muscle atrophy.
Chen H, Qian Z, Zhang S, Tang J, Fang L, Jiang F, Ge D, Chang J, Cao J, Yang L, Cao X
Redox biology 2021 Jan;38:101774
Redox biology 2021 Jan;38:101774
RND3 attenuates oxidative stress and vascular remodeling in spontaneously hypertensive rat via inhibiting ROCK1 signaling.
Wu N, Zheng F, Li N, Han Y, Xiong XQ, Wang JJ, Chen Q, Li YH, Zhu GQ, Zhou YB
Redox biology 2021 Dec;48:102204
Redox biology 2021 Dec;48:102204
Normothermic machine perfusion attenuates hepatic ischaemia-reperfusion injury by inhibiting CIRP-mediated oxidative stress and mitochondrial fission.
Liu W, Fan Y, Ding H, Han D, Yan Y, Wu R, Lv Y, Zheng X
Journal of cellular and molecular medicine 2021 Dec;25(24):11310-11321
Journal of cellular and molecular medicine 2021 Dec;25(24):11310-11321
Maternal supply of cysteamine alleviates oxidative stress and enhances angiogenesis in porcine placenta.
Huang S, Wu Z, Huang Z, Hao X, Zhang L, Hu C, Wei J, Deng J, Tan C
Journal of animal science and biotechnology 2021 Aug 10;12(1):91
Journal of animal science and biotechnology 2021 Aug 10;12(1):91
Ginkgetin Alleviates Inflammation, Oxidative Stress, and Apoptosis Induced by Hypoxia/Reoxygenation in H9C2 Cells via Caspase-3 Dependent Pathway.
Liu X, Bian H, Dou QL, Huang XW, Tao WY, Liu WH, Li N, Zhang WW
BioMed research international 2020;2020:1928410
BioMed research international 2020;2020:1928410
Brevilin A Inhibits STAT3 Signaling and Induces ROS-Dependent Apoptosis, Mitochondrial Stress and Endoplasmic Reticulum Stress in MCF-7 Breast Cancer Cells.
Saleem MZ, Nisar MA, Alshwmi M, Din SRU, Gamallat Y, Khan M, Ma T
OncoTargets and therapy 2020;13:435-450
OncoTargets and therapy 2020;13:435-450
Targeting Epstein-Barr virus oncoprotein LMP1-mediated high oxidative stress suppresses EBV lytic reactivation and sensitizes tumors to radiation therapy.
Hu J, Li Y, Li H, Shi F, Xie L, Zhao L, Tang M, Luo X, Jia W, Fan J, Zhou J, Gao Q, Qiu S, Wu W, Zhang X, Liao W, Bode AM, Cao Y
Theranostics 2020;10(26):11921-11937
Theranostics 2020;10(26):11921-11937
Magnesium isoglycyrrhizinate alleviates fructose-induced liver oxidative stress and inflammatory injury through suppressing NOXs.
Yang YZ, Liu ZH, Wang SC, Zhang XQ, Xu HJ, Yang L, Kong LD
European journal of pharmacology 2020 Sep 15;883:173314
European journal of pharmacology 2020 Sep 15;883:173314
Protective effect of Berberine on reproductive function and spermatogenesis in diabetic rats via inhibition of ROS/JAK2/NFκB pathway.
Song J, Gao X, Tang Z, Li H, Ruan Y, Liu Z, Wang T, Wang S, Liu J, Jiang H
Andrology 2020 May;8(3):793-806
Andrology 2020 May;8(3):793-806
MiR155-5p Inhibits Cell Migration and Oxidative Stress in Vascular Smooth Muscle Cells of Spontaneously Hypertensive Rats.
Wu N, Ye C, Zheng F, Wan GW, Wu LL, Chen Q, Li YH, Kang YM, Zhu GQ
Antioxidants (Basel, Switzerland) 2020 Mar 1;9(3)
Antioxidants (Basel, Switzerland) 2020 Mar 1;9(3)
Cathelicidin Modulates Vascular Smooth Muscle Cell Phenotypic Switching through ROS/IL-6 Pathway.
Dong X, Wu D, Zhang Y, Jia L, Pan X, Sun J, Pan LL
Antioxidants (Basel, Switzerland) 2020 Jun 5;9(6)
Antioxidants (Basel, Switzerland) 2020 Jun 5;9(6)
p47phox deficiency impairs platelet function and protects mice against arterial and venous thrombosis.
Wang X, Zhang S, Ding Y, Tong H, Xu X, Wei G, Chen Y, Ju W, Fu C, Qi K, Li Z, Zeng L, Xu K, Qiao J
Redox biology 2020 Jul;34:101569
Redox biology 2020 Jul;34:101569
The Role of Testosterone in Amplifying the Effect of a Phosphodiesterase Type 5 Inhibitor After Pelvic Irradiation.
Lee DS, Sohn DW
The journal of sexual medicine 2020 Jul;17(7):1268-1279
The journal of sexual medicine 2020 Jul;17(7):1268-1279
Increased Blood Pressure Causes Lymphatic Endothelial Dysfunction via Oxidative Stress in Spontaneously Hypertensive Rats.
Mukohda M, Mizuno R, Ozaki H
Hypertension (Dallas, Tex. : 1979) 2020 Aug;76(2):598-606
Hypertension (Dallas, Tex. : 1979) 2020 Aug;76(2):598-606
BCL6 Attenuates Proliferation and Oxidative Stress of Vascular Smooth Muscle Cells in Hypertension.
Chen D, Zang YH, Qiu Y, Zhang F, Chen AD, Wang JJ, Chen Q, Li YH, Kang YM, Zhu GQ
Oxidative medicine and cellular longevity 2019;2019:5018410
Oxidative medicine and cellular longevity 2019;2019:5018410
Propofol Alleviates DNA Damage Induced by Oxygen Glucose Deprivation and Reperfusion via FoxO1 Nuclear Translocation in H9c2 Cells.
Zhou D, Zhuang J, Wang Y, Zhao D, Zhao L, Zhu S, Pu J, Yin M, Zhang H, Wang Z, Hong J
Frontiers in physiology 2019;10:223
Frontiers in physiology 2019;10:223
Protective Effects of 18β-Glycyrrhetinic Acid on Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats.
Zhang M, Chang Z, Zhao F, Zhang P, Hao YJ, Yan L, Liu N, Wang JL, Bo L, Ma P, Zhou W, Ma X, Xu QB, Zhou R
Frontiers in pharmacology 2019;10:13
Frontiers in pharmacology 2019;10:13
Human tissue kallikrein-1 protects against the development of erectile dysfunction in a rat model of hyperhomocysteinemia.
Cui K, Luan Y, Tang Z, Li CC, Wang T, Wang SG, Chen Z, Liu JH
Asian journal of andrology 2019 Sep-Oct;21(5):508-515
Asian journal of andrology 2019 Sep-Oct;21(5):508-515
Astragaloside IV alleviates doxorubicin induced cardiomyopathy by inhibiting NADPH oxidase derived oxidative stress.
Lin J, Fang L, Li H, Li Z, Lyu L, Wang H, Xiao J
European journal of pharmacology 2019 Sep 15;859:172490
European journal of pharmacology 2019 Sep 15;859:172490
Allicin ameliorates obesity comorbid depressive-like behaviors: involvement of the oxidative stress, mitochondrial function, autophagy, insulin resistance and NOX/Nrf2 imbalance in mice.
Gao W, Wang W, Zhang J, Deng P, Hu J, Yang J, Deng Z
Metabolic brain disease 2019 Oct;34(5):1267-1280
Metabolic brain disease 2019 Oct;34(5):1267-1280
(Pro)renin Receptor is Involved in Myocardial Damage in Alcoholic Cardiomyopathy.
Xiong J, Cao X, Qiao S, Yu S, Li L, Yu Y, Fu C, Jiang F, Dong B, Su Q
Alcoholism, clinical and experimental research 2019 Nov;43(11):2344-2353
Alcoholism, clinical and experimental research 2019 Nov;43(11):2344-2353
MicroRNA-24 inhibits the oxidative stress induced by vascular injury by activating the Nrf2/Ho-1 signaling pathway.
Zhang J, Cai W, Fan Z, Yang C, Wang W, Xiong M, Ma C, Yang J
Atherosclerosis 2019 Nov;290:9-18
Atherosclerosis 2019 Nov;290:9-18
Exogenous hydrogen sulfide protects against high glucose-induced apoptosis and oxidative stress by inhibiting the STAT3/HIF-1α pathway in H9c2 cardiomyocytes.
Li J, Yuan YQ, Zhang L, Zhang H, Zhang SW, Zhang Y, Xuan XX, Wang MJ, Zhang JY
Experimental and therapeutic medicine 2019 Nov;18(5):3948-3958
Experimental and therapeutic medicine 2019 Nov;18(5):3948-3958
Role of JAK2 in the Pathogenesis of Diabetic Erectile Dysfunction and an Intervention With Berberine.
Song J, Tang Z, Li H, Jiang H, Sun T, Lan R, Wang T, Wang S, Ye Z, Liu J
The journal of sexual medicine 2019 Nov;16(11):1708-1720
The journal of sexual medicine 2019 Nov;16(11):1708-1720
Chronic fetal hypoxia disrupts the peri-conceptual environment in next-generation adult female rats.
Aiken CE, Tarry-Adkins JL, Spiroski AM, Nuzzo AM, Ashmore TJ, Rolfo A, Sutherland MJ, Camm EJ, Giussani DA, Ozanne SE
The Journal of physiology 2019 May;597(9):2391-2401
The Journal of physiology 2019 May;597(9):2391-2401
Growth differentiation factor 11 is involved in isoproterenol‑induced heart failure.
Zhang XJ, Tan H, Shi ZF, Li N, Jia Y, Hao Z
Molecular medicine reports 2019 May;19(5):4109-4118
Molecular medicine reports 2019 May;19(5):4109-4118
Oxidative and endoplasmic reticulum stresses are involved in palmitic acid-induced H9c2 cell apoptosis.
Yang L, Guan G, Lei L, Liu J, Cao L, Wang X
Bioscience reports 2019 May 31;39(5)
Bioscience reports 2019 May 31;39(5)
Chronic gestational hypoxia accelerates ovarian aging and lowers ovarian reserve in next-generation adult rats.
Aiken CE, Tarry-Adkins JL, Spiroski AM, Nuzzo AM, Ashmore TJ, Rolfo A, Sutherland MJ, Camm EJ, Giussani DA, Ozanne SE
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jun;33(6):7758-7766
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jun;33(6):7758-7766
Testosterone preserves endothelial function through regulation of S1P1/Akt/FOXO3a signalling pathway in the rat corpus cavernosum.
Cui K, Li R, Liu K, Wang T, Liu J, Rao K
Andrologia 2019 Feb;51(1):e13173
Andrologia 2019 Feb;51(1):e13173
Sensory plasticity of carotid body is correlated with oxidative stress in paraventricular nucleus during chronic intermittent hypoxia.
Liu P, Zhang HM, Hu K, Zhou XF, Tang S
Journal of cellular physiology 2019 Aug;234(8):13534-13543
Journal of cellular physiology 2019 Aug;234(8):13534-13543
Inhibiting inflammation and modulating oxidative stress in oxalate-induced nephrolithiasis with the Nrf2 activator dimethyl fumarate.
Zhu J, Wang Q, Li C, Lu Y, Hu H, Qin B, Xun Y, Zhu Y, Wu Y, Zhang J, Wang S
Free radical biology & medicine 2019 Apr;134:9-22
Free radical biology & medicine 2019 Apr;134:9-22
Calcium Release from Endoplasmic Reticulum Involves Calmodulin-Mediated NADPH Oxidase-Derived Reactive Oxygen Species Production in Endothelial Cells.
Sakurada R, Odagiri K, Hakamata A, Kamiya C, Wei J, Watanabe H
International journal of molecular sciences 2019 Apr 2;20(7)
International journal of molecular sciences 2019 Apr 2;20(7)
Downregulated Expression of Solute Carrier Family 26 Member 6 in NRK-52E Cells Attenuates Oxalate-Induced Intracellular Oxidative Stress.
Jiang H, Gao X, Gong J, Yang Q, Lan R, Wang T, Liu J, Yin C, Wang S, Liu Z
Oxidative medicine and cellular longevity 2018;2018:1724648
Oxidative medicine and cellular longevity 2018;2018:1724648
Losartan Ameliorates Calcium Oxalate-Induced Elevation of Stone-Related Proteins in Renal Tubular Cells by Inhibiting NADPH Oxidase and Oxidative Stress.
Qin B, Wang Q, Lu Y, Li C, Hu H, Zhang J, Wang Y, Zhu J, Zhu Y, Xun Y, Wang S
Oxidative medicine and cellular longevity 2018;2018:1271864
Oxidative medicine and cellular longevity 2018;2018:1271864
Notch inhibitor can attenuate apparent diffusion coefficient and improve neurological function through downregulating NOX2-ROS in severe traumatic brain injury.
Zhang HM, Chen W, Liu RN, Zhao Y
Drug design, development and therapy 2018;12:3847-3854
Drug design, development and therapy 2018;12:3847-3854
BRG1 regulates NOX gene transcription in endothelial cells and contributes to cardiac ischemia-reperfusion injury.
Li Z, Zhang X, Liu S, Zeng S, Yu L, Yang G, Guo J, Xu Y
Biochimica et biophysica acta. Molecular basis of disease 2018 Oct;1864(10):3477-3486
Biochimica et biophysica acta. Molecular basis of disease 2018 Oct;1864(10):3477-3486
Myocardin-related transcription factor A (MRTF-A) contributes to acute kidney injury by regulating macrophage ROS production.
Liu L, Wu X, Xu H, Yu L, Zhang X, Li L, Jin J, Zhang T, Xu Y
Biochimica et biophysica acta. Molecular basis of disease 2018 Oct;1864(10):3109-3121
Biochimica et biophysica acta. Molecular basis of disease 2018 Oct;1864(10):3109-3121
Lipoxin A4 improves erectile dysfunction in rats with type I diabetes by inhibiting oxidative stress and corporal fibrosis.
Cui K, Tang Z, Li CC, Wang T, Rao K, Wang SG, Liu JH, Chen Z
Asian journal of andrology 2018 Mar-Apr;20(2):166-172
Asian journal of andrology 2018 Mar-Apr;20(2):166-172
Argirein alleviates vascular endothelial insulin resistance through suppressing the activation of Nox4-dependent O(2)(-) production in diabetic rats.
Li Q, Su J, Jin SJ, Wei W, Cong XD, Li XX, Xu M
Free radical biology & medicine 2018 Jun;121:169-179
Free radical biology & medicine 2018 Jun;121:169-179
Megakaryocytic Leukemia 1 Bridges Epigenetic Activation of NADPH Oxidase in Macrophages to Cardiac Ischemia-Reperfusion Injury.
Yu L, Yang G, Zhang X, Wang P, Weng X, Yang Y, Li Z, Fang M, Xu Y, Sun A, Ge J
Circulation 2018 Dec 11;138(24):2820-2836
Circulation 2018 Dec 11;138(24):2820-2836
MitoTEMPO Prevents Oxalate Induced Injury in NRK-52E Cells via Inhibiting Mitochondrial Dysfunction and Modulating Oxidative Stress.
Zhang J, Wang Q, Xu C, Lu Y, Hu H, Qin B, Wang Y, He D, Li C, Yu X, Wang S, Liu J
Oxidative medicine and cellular longevity 2017;2017:7528090
Oxidative medicine and cellular longevity 2017;2017:7528090
Berberine ameliorates fatty acid-induced oxidative stress in human hepatoma cells.
Sun Y, Yuan X, Zhang F, Han Y, Chang X, Xu X, Li Y, Gao X
Scientific reports 2017 Sep 12;7(1):11340
Scientific reports 2017 Sep 12;7(1):11340
Therapeutic effect of human ghrelin and growth hormone: Attenuation of immunosuppression in septic aged rats.
Zhou M, Yang WL, Aziz M, Ma G, Wang P
Biochimica et biophysica acta. Molecular basis of disease 2017 Oct;1863(10 Pt B):2584-2593
Biochimica et biophysica acta. Molecular basis of disease 2017 Oct;1863(10 Pt B):2584-2593
Activation of ATP-sensitive potassium channel by iptakalim normalizes stress-induced HPA axis disorder and depressive behaviour by alleviating inflammation and oxidative stress in mouse hypothalamus.
Zhao XJ, Zhao Z, Yang DD, Cao LL, Zhang L, Ji J, Gu J, Huang JY, Sun XL
Brain research bulletin 2017 Apr;130:146-155
Brain research bulletin 2017 Apr;130:146-155
Nitro-oleic acid ameliorates oxygen and glucose deprivation/re-oxygenation triggered oxidative stress in renal tubular cells via activation of Nrf2 and suppression of NADPH oxidase.
Nie H, Xue X, Liu G, Guan G, Liu H, Sun L, Zhao L, Wang X, Chen Z
Free radical research 2016;50(11):1200-1213
Free radical research 2016;50(11):1200-1213
Poor maternal nutrition and accelerated postnatal growth induces an accelerated aging phenotype and oxidative stress in skeletal muscle of male rats.
Tarry-Adkins JL, Fernandez-Twinn DS, Chen JH, Hargreaves IP, Neergheen V, Aiken CE, Ozanne SE
Disease models & mechanisms 2016 Oct 1;9(10):1221-1229
Disease models & mechanisms 2016 Oct 1;9(10):1221-1229
Chlorogenic acid protects against liver fibrosis in vivo and in vitro through inhibition of oxidative stress.
Shi H, Shi A, Dong L, Lu X, Wang Y, Zhao J, Dai F, Guo X
Clinical nutrition (Edinburgh, Scotland) 2016 Dec;35(6):1366-1373
Clinical nutrition (Edinburgh, Scotland) 2016 Dec;35(6):1366-1373
PKCα promotes generation of reactive oxygen species via DUOX2 in hepatocellular carcinoma.
Wang J, Shao M, Liu M, Peng P, Li L, Wu W, Wang L, Duan F, Zhang M, Song S, Jia D, Ruan Y, Gu J
Biochemical and biophysical research communications 2015 Aug 7;463(4):839-45
Biochemical and biophysical research communications 2015 Aug 7;463(4):839-45
The phosphodiesterase-5 inhibitor vardenafil reduces oxidative stress while reversing pulmonary arterial hypertension.
Fan YF, Zhang R, Jiang X, Wen L, Wu DC, Liu D, Yuan P, Wang YL, Jing ZC
Cardiovascular research 2013 Aug 1;99(3):395-403
Cardiovascular research 2013 Aug 1;99(3):395-403
TIPE2, a novel regulator of immunity, protects against experimental stroke.
Zhang Y, Wei X, Liu L, Liu S, Wang Z, Zhang B, Fan B, Yang F, Huang S, Jiang F, Chen YH, Yi F
The Journal of biological chemistry 2012 Sep 21;287(39):32546-55
The Journal of biological chemistry 2012 Sep 21;287(39):32546-55
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The NOX2 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human NOX2. This antibody recognizes human,mouse,rat antigen. The NOX2 antibody has been validated for the following applications: ELISA, WB analysis.
