Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 21903-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- Nectin-4/PVRL4 antibody
- Antibody type
- Polyclonal
- Description
- Nectin-4/PVRL4 antibody (Cat. #21903-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, IF, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Interferon-stimulated gene PVRL4 broadly suppresses viral entry by inhibiting viral-cellular membrane fusion.
Chemotherapy with gemcitabine and cisplatin downregulates tumor expression level of nectin-4 in a syngeneic model of murine MBT2 urothelial cancer cell line and C3H mice.
Upregulation of nectin-4 is associated with ITGB1 and vasculogenic mimicry and may serve as a predictor of poor prognosis in colorectal cancer.
MiR-31 and miR-128 regulates poliovirus receptor-related 4 mediated measles virus infectivity in tumors.
Cai Q, Sun N, Zhang Y, Wang J, Pan C, Chen Y, Li L, Li X, Liu W, Aliyari SR, Yang H, Cheng G
Cell & bioscience 2024 Feb 17;14(1):23
Cell & bioscience 2024 Feb 17;14(1):23
Chemotherapy with gemcitabine and cisplatin downregulates tumor expression level of nectin-4 in a syngeneic model of murine MBT2 urothelial cancer cell line and C3H mice.
Miyake M, Oda Y, Nishimura N, Shimizu T, Fujii T, Fujimoto K
International journal of urology : official journal of the Japanese Urological Association 2023 Mar;30(3):328-330
International journal of urology : official journal of the Japanese Urological Association 2023 Mar;30(3):328-330
Upregulation of nectin-4 is associated with ITGB1 and vasculogenic mimicry and may serve as a predictor of poor prognosis in colorectal cancer.
Zhang J, Liu K, Peng P, Li S, Ye Z, Su Y, Liu S, Qin M, Huang J
Oncology letters 2019 Aug;18(2):1163-1170
Oncology letters 2019 Aug;18(2):1163-1170
MiR-31 and miR-128 regulates poliovirus receptor-related 4 mediated measles virus infectivity in tumors.
Geekiyanage H, Galanis E
Molecular oncology 2016 Nov;10(9):1387-1403
Molecular oncology 2016 Nov;10(9):1387-1403
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The PVRL4 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human PVRL4. This antibody recognizes human, mouse antigen. The PVRL4 antibody has been validated for the following applications: ELISA, WB analysis.