RA0620

antibody from Oursmab

Targeting: NECTIN4 LNIR, nectin-4, PRR4, PVRL4

Western blot (Supportive data in Antibodypedia)

ELISA (Supportive data in Antibodypedia)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0620

Provider

Oursmab

Product name

Enfortumab (Biosimilar Reference Antibody) (PVRL4)

Antibody type

Monoclonal

Description

Enfortumab vedotin is an antibody-drug conjugate (ADC) approved for the treatment of locally advanced or metastatic urothelial carcinoma. It consists of a fully human monoclonal antibody linked to a potent cytotoxic payload, monomethyl auristatin E (MMAE), via a protease-cleavable linker. Enfortumab vedotin functions as a targeted delivery system for chemotherapy. The antibody component specifically binds to Nectin-4 on cancer cells, leading to ADC internalization. Inside the cell, the linker is cleaved, releasing MMAE, which disrupts microtubule networks, inhibits cell division, and induces programmed cell death.

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.

Western blot

Supportive validation

Submitted by

Oursmab (provider)

Main image

Experimental details

Enfortumab (Biosimilar Reference Antibody) (PVRL4)-RA0620-Oursmab determined by SDS-PAGE. The purity of the protein is greater than 98%.

ELISA

Supportive validation

Submitted by

Oursmab (provider)

Main image

Experimental details

ELISA plate pre-coated Antigen protein, can bind Enfortumab (Biosimilar Reference Antibody) (PVRL4)-RA0620 in a linear range of 3.91-125 ng/mL.