15625-1-AP

antibody from Proteintech Group

Targeting: FCGR2A CD32, CD32A, CDw32, FCG2, FCGR2, FCGR2A1, IGFR2

Provider product page for 15625-1-AP

Western blot

ELISA

Flow cytometry

Antibody data

Antibody Data
Antigen structure
References [19]
Comments [0]
Validations
Western blot [1]

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Product number: 15625-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#15625-1-AP, RRID:AB_2246912
Product name: FCGR2A / CD32a antibody
Antibody type: Polyclonal
Description: FCGR2A / CD32a antibody (Cat. #15625-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: FC, WB,ELISA.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

FCGR2A protein structure - 15625-1-AP shown in red.

Submitted references Multiomics Profiling Reveals Distinct Immunosuppression and Metabolic Dysregulation in Aggressive Subtypes of Thyroid Cancer.

Gui S, Huang K, Qiang J, Chen Y, Gan M, Jiang Z, Qian J, Yi C, Ding Y, Jiang H, Zheng F, Lei W, Jin L, Zhang X, Fang H, Wang M
Molecular & cellular proteomics : MCP 2026 Mar;25(3):101513

Genome-wide mapping of RNA-protein associations through sequencing.

Qi Z, Xue S, Chen J, Zhao W, Johnson K, Wen X, Charles Richard JL, Lin P, Zhong S
Nature biotechnology 2025 Sep 9;

Tetrahydroxy Stilbene Glycoside Reduces Abeta Deposition by Modulating Microglia Activation and via TREM2/PI3K/AKT Pathway in APP/PS1 Mice.

Li M, Song Q, Jie S, Wang C, Zhang C, Chi K, Gao Y, Li T
Basic & clinical pharmacology & toxicology 2025 Mar;136(3):e70008

Apabetalone alleviates ligature-induced periodontitis by inhibiting M1 macrophage polarization via an immunometabolic shift.

Bian T, Li H, Liu H, Guo M, Zhang Y, Hu P, Chen M
International immunopharmacology 2025 Mar 26;150:114279

Infiltrating plasma cells maintain glioblastoma stem cells through IgG-Tumor binding.

Gao J, Gu D, Yang K, Zhang J, Lin Q, Yuan W, Zhu X, Dixit D, Gimple RC, You H, Zhang Q, Shi Z, Fan X, Wu Q, Lu C, Cheng Z, Li D, Zhao L, Xue B, Zhu Z, Zhu Z, Yang H, Zhao N, Gao W, Lu Y, Shao J, Cheng C, Hao D, Yang S, Chen Y, Wang X, Kang C, Ji J, Man J, Agnihotri S, Wang Q, Lin F, Qian X, Mack SC, Hu Z, Li C, Taylor MD, Li Y, Zhang N, Rich JN, You Y, Wang X
Cancer cell 2025 Jan 13;43(1):122-143.e8

Morin Regulates M1/M2 Microglial Polarization via NF-κB p65 to Alleviate Vincristine-Induced Neuropathic Pain.

Shao Y, Chen Y, Lan X, Lu J, Tang G, Tang S, Zhai R, Chen C, Xiong X, Shi J
Drug design, development and therapy 2024;18:3143-3156

Esketamine improves cognitive function in sepsis-associated encephalopathy by inhibiting microglia-mediated neuroinflammation.

Li H, Hu W, Wu Z, Tian B, Ren Y, Zou X
European journal of pharmacology 2024 Nov 15;983:177014

The cGAS/STING signaling pathway is involved in sevoflurane induced neuronal necroptosis via regulating microglia M1 polarization.

Zhang Q, Li Y, Liu Y, Wang X, Yang Y, Shi L
Cellular signalling 2024 Jul;119:111195

Ye Z, Huang N, Fu Y, Tian R, Wang L, Huang W
eLife 2024 Jul 9;13

Spinosin improves anxiety disorders in mice with chronic restraint stress via the ERK1/2-CREB-BDNF pathway.

Guo Y, Wei F, Lv Y, Wu H, Li Y, Tang R, Zhao M, Ge W, Du W
International immunopharmacology 2024 Dec 25;143(Pt 2):113517

Ursolic Acid Alleviates Neuroinflammation after Intracerebral Hemorrhage by Mediating Microglial Pyroptosis via the NF-κB/NLRP3/GSDMD Pathway.

Lei P, Li Z, Hua Q, Song P, Gao L, Zhou L, Cai Q
International journal of molecular sciences 2023 Sep 30;24(19)

FCGR2A as one novel potential target for poor survival prognosis of clear cell renal cell carcinoma.

Fu T, Zhang L, Zuo M, Li F, Shi C, Chen H
Medicine 2023 Mar 17;102(11):e33324

Accelerate wound healing by microscale gel array patch encapsulating defined SDF-1α gradient.

Xu Z, Wu J, Gong P, Chang C
Journal of controlled release : official journal of the Controlled Release Society 2023 Jun;358:1-12

Grossamide attenuates inflammation by balancing macrophage polarization through metabolic reprogramming of macrophages in mice.

Zhao W, Xu D, Hong W, Zhang L, Wu Q, Gao M, Wang J
International immunopharmacology 2022 Nov;112:109190

Pentraxin 3 regulated by miR-224-5p modulates macrophage reprogramming and exacerbates osteoarthritis associated synovitis by targeting CD32.

Yin J, Zeng H, Fan K, Xie H, Shao Y, Lu Y, Zhu J, Yao Z, Liu L, Zhang H, Luo B, Wang X, Zeng C, Bai X, Zhang H, Cai D
Cell death & disease 2022 Jun 24;13(6):567

Protein Disulfide Isomerase Inhibitor Suppresses Viral Replication and Production during Antibody-Dependent Enhancement of Dengue Virus Infection in Human Monocytic Cells.

Rawarak N, Suttitheptumrong A, Reamtong O, Boonnak K, Pattanakitsakul SN
Viruses 2019 Feb 13;11(2)

Photobiomodulation therapy promotes neurogenesis by improving post-stroke local microenvironment and stimulating neuroprogenitor cells.

Yang L, Tucker D, Dong Y, Wu C, Lu Y, Li Y, Zhang J, Liu TC, Zhang Q
Experimental neurology 2018 Jan;299(Pt A):86-96

Treadmill Exercise Exerts Neuroprotection and Regulates Microglial Polarization and Oxidative Stress in a Streptozotocin-Induced Rat Model of Sporadic Alzheimer's Disease.

Lu Y, Dong Y, Tucker D, Wang R, Ahmed ME, Brann D, Zhang Q
Journal of Alzheimer's disease : JAD 2017;56(4):1469-1484

FcγRIIa ligation induces platelet hypersensitivity to thrombotic stimuli.

Berlacher MD, Vieth JA, Heflin BC, Gay SR, Antczak AJ, Tasma BE, Boardman HJ, Singh N, Montel AH, Kahaleh MB, Worth RG
The American journal of pathology 2013 Jan;182(1):244-54

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The CD32 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CD32. This antibody recognizes human antigen. The CD32 antibody has been validated for the following applications: ELISA, WB analysis.
Appendix: 15625-1-AP.pdf

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