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- Antigen structure
- References [15]
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- Product number
- 12107-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12107-1-AP, RRID:AB_2290335
- Product name
- BCOR antibody
- Antibody type
- Polyclonal
- Description
- BCOR antibody (Cat. #12107-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Locus-specific proteomics identifies novel regulators of Epstein-Barr virus lytic reactivation.
SKP1A bound to Polycomb-silenced genes mediates degradation of PRC2 and preconditions their activation.
Analysis of a BCOR internal tandem duplication in mouse embryonic stem cell to neuronal precursor differentiation.
Non-canonical PRC1.1 licenses transcriptional response to enable Treg plasticity in immune adaptation.
Epigenetic regulation of noncanonical menin targets modulates menin inhibitor response in acute myeloid leukemia.
NUP98 fusion proteins and KMT2A-MENIN antagonize PRC1.1 to drive gene expression in AML.
PCGF1-PRC1 links chromatin repression with DNA replication during hematopoietic cell lineage commitment.
BCOR and BCORL1 Mutations Drive Epigenetic Reprogramming and Oncogenic Signaling by Unlinking PRC1.1 from Target Genes.
Bimodal regulation of the PRC2 complex by USP7 underlies tumorigenesis.
BCOR Internal Tandem Duplication Expression in Neural Stem Cells Promotes Growth, Invasion, and Expression of PRC2 Targets.
DICER1 screening in 15 paediatric paratesticular sarcomas unveils an unusual DICER1-associated sarcoma.
Secreted frizzled-related protein 2 promotes the osteo/odontogenic differentiation and paracrine potentials of stem cells from apical papilla under inflammation and hypoxia conditions.
Novel exon-exon breakpoint in CIC-DUX4 fusion sarcoma identified by anchored multiplex PCR (Archer FusionPlex Sarcoma Panel).
Loss of Polycomb Group Protein Pcgf1 Severely Compromises Proper Differentiation of Embryonic Stem Cells.
Consistent in-frame internal tandem duplications of BCOR characterize clear cell sarcoma of the kidney.
Greaves DE, Gabaev I, Williamson JC, Bloor S, Martinez Cuesta S, Matheson NJ, Frappier L, Déjardin J, Lehner PJ
Journal of virology 2026 Apr 21;100(4):e0140825
Journal of virology 2026 Apr 21;100(4):e0140825
SKP1A bound to Polycomb-silenced genes mediates degradation of PRC2 and preconditions their activation.
Kondo T, Ito S, Takano J, Han YW, Endo T, Kondo K, Shibata M, Kawashima Y, Sugishita H, Harachi M, Sharif J, Seita J, Ohara O, Nakayama M, Koseki H
Molecular cell 2025 Sep 4;85(17):3306-3320.e6
Molecular cell 2025 Sep 4;85(17):3306-3320.e6
Analysis of a BCOR internal tandem duplication in mouse embryonic stem cell to neuronal precursor differentiation.
Dhoondia Z, Kang H, Lee K, Cole PA, Kuroda MI
Genetics 2025 Sep 3;231(1)
Genetics 2025 Sep 3;231(1)
Non-canonical PRC1.1 licenses transcriptional response to enable Treg plasticity in immune adaptation.
Li T, Zhao Y, Li Q, Sun Z, Wang N, Xing L, Tang N, Mao R, Wang Y, Su J, Huo D, Dong F, Zhao X, Cao L, Kong Y, Gong M, Liu Z, Li W, Lv X, Ning H, Hu D, Zhou Y, Li B, Feng X, Helin K, Chen FX, Wu X
Molecular cell 2025 Jul 3;85(13):2517-2534.e6
Molecular cell 2025 Jul 3;85(13):2517-2534.e6
Epigenetic regulation of noncanonical menin targets modulates menin inhibitor response in acute myeloid leukemia.
Zhou X, Zhang L, Aryal S, Veasey V, Tajik A, Restelli C, Moreira S, Zhang P, Zhang Y, Hope KJ, Zhou Y, Cheng C, Bhatia R, Lu R
Blood 2024 Nov 7;144(19):2018-2032
Blood 2024 Nov 7;144(19):2018-2032
NUP98 fusion proteins and KMT2A-MENIN antagonize PRC1.1 to drive gene expression in AML.
Heikamp EB, Martucci C, Henrich JA, Neel DS, Mahendra-Rajah S, Rice H, Wenge DV, Perner F, Wen Y, Hatton C, Armstrong SA
Cell reports 2024 Nov 26;43(11):114901
Cell reports 2024 Nov 26;43(11):114901
PCGF1-PRC1 links chromatin repression with DNA replication during hematopoietic cell lineage commitment.
Takano J, Ito S, Dong Y, Sharif J, Nakajima-Takagi Y, Umeyama T, Han YW, Isono K, Kondo T, Iizuka Y, Miyai T, Koseki Y, Ikegaya M, Sakihara M, Nakayama M, Ohara O, Hasegawa Y, Hashimoto K, Arner E, Klose RJ, Iwama A, Koseki H, Ikawa T
Nature communications 2022 Nov 28;13(1):7159
Nature communications 2022 Nov 28;13(1):7159
BCOR and BCORL1 Mutations Drive Epigenetic Reprogramming and Oncogenic Signaling by Unlinking PRC1.1 from Target Genes.
Schaefer EJ, Wang HC, Karp HQ, Meyer CA, Cejas P, Gearhart MD, Adelman ER, Fares I, Apffel A, Lim K, Xie Y, Gibson CJ, Schenone M, Murdock HM, Wang ES, Gondek LP, Carroll MP, Vedula RS, Winer ES, Garcia JS, Stone RM, Luskin MR, Carr SA, Long HW, Bardwell VJ, Figueroa ME, Lindsley RC
Blood cancer discovery 2022 Mar 1;3(2):116-135
Blood cancer discovery 2022 Mar 1;3(2):116-135
Bimodal regulation of the PRC2 complex by USP7 underlies tumorigenesis.
Su D, Wang W, Hou Y, Wang L, Yi X, Cao C, Wang Y, Gao H, Wang Y, Yang C, Liu B, Chen X, Wu X, Wu J, Yan D, Wei S, Han L, Liu S, Wang Q, Shi L, Shan L
Nucleic acids research 2021 May 7;49(8):4421-4440
Nucleic acids research 2021 May 7;49(8):4421-4440
BCOR Internal Tandem Duplication Expression in Neural Stem Cells Promotes Growth, Invasion, and Expression of PRC2 Targets.
Nakata S, Yuan M, Rubens JA, Kahlert UD, Maciaczyk J, Raabe EH, Eberhart CG
International journal of molecular sciences 2021 Apr 10;22(8)
International journal of molecular sciences 2021 Apr 10;22(8)
DICER1 screening in 15 paediatric paratesticular sarcomas unveils an unusual DICER1-associated sarcoma.
Apellaniz-Ruiz M, Cullinan N, Grant R, Marrano P, Priest JR, Thorner PS, Goudie C, Foulkes WD
The journal of pathology. Clinical research 2020 Jul;6(3):185-194
The journal of pathology. Clinical research 2020 Jul;6(3):185-194
Secreted frizzled-related protein 2 promotes the osteo/odontogenic differentiation and paracrine potentials of stem cells from apical papilla under inflammation and hypoxia conditions.
Yang H, Li G, Han N, Zhang X, Cao Y, Cao Y, Fan Z
Cell proliferation 2020 Jan;53(1):e12694
Cell proliferation 2020 Jan;53(1):e12694
Novel exon-exon breakpoint in CIC-DUX4 fusion sarcoma identified by anchored multiplex PCR (Archer FusionPlex Sarcoma Panel).
Loke BN, Lee VKM, Sudhanshi J, Wong MK, Kuick CH, Puhaindran M, Chang KTE
Journal of clinical pathology 2017 Aug;70(8):697-701
Journal of clinical pathology 2017 Aug;70(8):697-701
Loss of Polycomb Group Protein Pcgf1 Severely Compromises Proper Differentiation of Embryonic Stem Cells.
Yan Y, Zhao W, Huang Y, Tong H, Xia Y, Jiang Q, Qin J
Scientific reports 2017 Apr 10;7:46276
Scientific reports 2017 Apr 10;7:46276
Consistent in-frame internal tandem duplications of BCOR characterize clear cell sarcoma of the kidney.
Ueno-Yokohata H, Okita H, Nakasato K, Akimoto S, Hata J, Koshinaga T, Fukuzawa M, Kiyokawa N
Nature genetics 2015 Aug;47(8):861-3
Nature genetics 2015 Aug;47(8):861-3
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The BCOR antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human BCOR. This antibody recognizes human, mouse, rat antigen. The BCOR antibody has been validated for the following applications: ELISA, WB analysis.
