KCNC1

This gene encodes a member of a family of integral membrane proteins that mediate the voltage-dependent potassium ion permeability of excitable membranes. Alternative splicing is thought to result in two transcript variants encoding isoforms that differ at their C-termini. These isoforms have had conflicting names in the literature: the longer isoform has been called both ""b"" and ""alpha"", while the shorter isoform has been called both ""a"" and ""beta"" (PMIDs 1432046, 12091563). [provided by RefSeq, Oct 2014]

Description

potassium voltage-gated channel subfamily C member 1

Protein family

Disease related genes, FDA approved drug targets, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Predicted membrane proteins, Protein evidence (Peptideatlas), Transporters, Voltage-gated ion channels

Chromosome

11:p15.1 (17734774 - 17856804)

Ensembl ID

ENSG00000129159  (ver. 99.38)

Orthologs

Mouse Kcnc1: ENSMUSG00000058975

UniProt

P48547

neXtProt

NX_P48547

Human splice variants
Mouse splice variants