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- References [14]
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- Product number
- 11338-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11338-1-AP, RRID:AB_2196730
- Product name
- SUV39H2 antibody
- Antibody type
- Polyclonal
- Description
- SUV39H2 antibody (Cat. #11338-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Improving erectile function in diabetic male mice by rescuing depalmitoylated FBP1 to reduce cavernosal lactate.
Role of SUV39H2 in shaping the malignant phenotype of triple-negative breast cancer.
Requirements for establishment and epigenetic stability of mammalian heterochromatin.
SUV39H2 is a vulnerability in glioblastoma stem cells enhanced by co-targeting SUV39H1.
The ZBTB24-CDCA7-HELLS axis suppresses the totipotent 2C-like reprogramming by maintaining Dux methylation and repression.
Inhibition of protein kinase C increases Prdm14 level to promote self-renewal of embryonic stem cells through reducing Suv39h-induced H3K9 methylation.
Lysine methylation of PPP1CA by the methyltransferase SUV39H2 disrupts TFEB-dependent autophagy and promotes intervertebral disc degeneration.
ATM, KAP1 and the Epstein-Barr virus polymerase processivity factor direct traffic at the intersection of transcription and replication.
N(6) -Methyladenosine-Modified CBX1 Regulates Nasopharyngeal Carcinoma Progression Through Heterochromatin Formation and STAT1 Activation.
Salvia-Nelumbinis naturalis improves lipid metabolism of NAFLD by regulating the SIRT1/AMPK signaling pathway.
DICER regulates the expression of major satellite repeat transcripts and meiotic chromosome segregation during spermatogenesis.
The histone methyltransferase Suv39h2 contributes to nonalcoholic steatohepatitis in mice.
Suv39h2 deficiency ameliorates diet-induced steatosis in mice.
Alternative splicing regulates the expression of G9A and SUV39H2 methyltransferases, and dramatically changes SUV39H2 functions.
Xiao M, Guo W, Zeng R, Wu S, Jin X
Nature communications 2026 Jan 16;17(1):1740
Nature communications 2026 Jan 16;17(1):1740
Role of SUV39H2 in shaping the malignant phenotype of triple-negative breast cancer.
Wang ZW, Hu S, Chen Y, Lu Y, Li SF, Deng Y, Jiang HT
Frontiers in oncology 2025;15:1679640
Frontiers in oncology 2025;15:1679640
Requirements for establishment and epigenetic stability of mammalian heterochromatin.
Tatarakis A, Saini H, Yu J, Feng W, Pinzon-Arteaga CA, Moazed D
Molecular cell 2025 Sep 18;85(18):3388-3406.e12
Molecular cell 2025 Sep 18;85(18):3388-3406.e12
SUV39H2 is a vulnerability in glioblastoma stem cells enhanced by co-targeting SUV39H1.
Cao B, Xie Q, Li C, Mast J, Wang B, Miao Q, Hamdouchi C, Grese TA, Shen J
Epigenomics 2025 Dec;17(17):1225-1232
Epigenomics 2025 Dec;17(17):1225-1232
The ZBTB24-CDCA7-HELLS axis suppresses the totipotent 2C-like reprogramming by maintaining Dux methylation and repression.
Guo D, Du Z, Liu Y, Lin M, Lu Y, Hardikar S, Xue Y, Zhang J, Chen T, Dan J
Nucleic acids research 2025 Apr 10;53(7)
Nucleic acids research 2025 Apr 10;53(7)
Inhibition of protein kinase C increases Prdm14 level to promote self-renewal of embryonic stem cells through reducing Suv39h-induced H3K9 methylation.
Ji J, Cao J, Chen P, Huang R, Ye SD
The Journal of biological chemistry 2024 Mar;300(3):105714
The Journal of biological chemistry 2024 Mar;300(3):105714
Lysine methylation of PPP1CA by the methyltransferase SUV39H2 disrupts TFEB-dependent autophagy and promotes intervertebral disc degeneration.
Liang H, Luo R, Li G, Zhang W, Zhu D, Wu D, Zhou X, Tong B, Wang B, Feng X, Wang K, Song Y, Yang C
Cell death and differentiation 2023 Sep;30(9):2135-2150
Cell death and differentiation 2023 Sep;30(9):2135-2150
ATM, KAP1 and the Epstein-Barr virus polymerase processivity factor direct traffic at the intersection of transcription and replication.
Xu H, Akinyemi IA, Haley J, McIntosh MT, Bhaduri-McIntosh S
Nucleic acids research 2023 Nov 10;51(20):11104-11122
Nucleic acids research 2023 Nov 10;51(20):11104-11122
N(6) -Methyladenosine-Modified CBX1 Regulates Nasopharyngeal Carcinoma Progression Through Heterochromatin Formation and STAT1 Activation.
Zhao Y, Huang S, Tan X, Long L, He Q, Liang X, Bai J, Li Q, Lin J, Li Y, Liu N, Ma J, Chen Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Dec;9(36):e2205091
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Dec;9(36):e2205091
Salvia-Nelumbinis naturalis improves lipid metabolism of NAFLD by regulating the SIRT1/AMPK signaling pathway.
Liu Y, Li Y, Wang J, Yang L, Yu X, Huang P, Song H, Zheng P
BMC complementary medicine and therapies 2022 Aug 9;22(1):213
BMC complementary medicine and therapies 2022 Aug 9;22(1):213
DICER regulates the expression of major satellite repeat transcripts and meiotic chromosome segregation during spermatogenesis.
Yadav RP, Mäkelä JA, Hyssälä H, Cisneros-Montalvo S, Kotaja N
Nucleic acids research 2020 Jul 27;48(13):7135-7153
Nucleic acids research 2020 Jul 27;48(13):7135-7153
The histone methyltransferase Suv39h2 contributes to nonalcoholic steatohepatitis in mice.
Fan Z, Li L, Li M, Zhang X, Hao C, Yu L, Zeng S, Xu H, Fang M, Shen A, Jenuwein T, Xu Y
Hepatology (Baltimore, Md.) 2017 Jun;65(6):1904-1919
Hepatology (Baltimore, Md.) 2017 Jun;65(6):1904-1919
Suv39h2 deficiency ameliorates diet-induced steatosis in mice.
Shao J, Li L, Xu H, Yang L, Bian Y, Fang M, Xu Y
Biochemical and biophysical research communications 2017 Apr 8;485(3):658-664
Biochemical and biophysical research communications 2017 Apr 8;485(3):658-664
Alternative splicing regulates the expression of G9A and SUV39H2 methyltransferases, and dramatically changes SUV39H2 functions.
Mauger O, Klinck R, Chabot B, Muchardt C, Allemand E, Batsché E
Nucleic acids research 2015 Feb 18;43(3):1869-82
Nucleic acids research 2015 Feb 18;43(3):1869-82
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SUV39H2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SUV39H2. This antibody recognizes human, mouse, rat antigen. The SUV39H2 antibody has been validated for the following applications: ELISA, WB analysis.
