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- Antibody Data
- Antigen structure
- References [6]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 66082-1-Ig - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#66082-1-Ig, RRID:AB_11232425
- Product name
- CISD2-Specific antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated CISD2-Specific antibody (Cat. #66082-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, zebrafish, rat, mouse and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat, Zebrafish
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 3D7A3
- Vial size
- 20ul, 150ul
Submitted references Hesperetin Alleviates Bleomycin-Induced Pulmonary Fibrosis by Modulating Cellular Senescence and Promoting Impaired Autophagy in a CISD2-Dependent Manner.
CISD2 ensures adequate ER-mitochondrial coupling, critically supporting mitochondrial function in neurons.
ER calcium depletion as a key driver for impaired ER-to-mitochondria calcium transfer and mitochondrial dysfunction in Wolfram syndrome.
Integrating apaQTL and eQTL analysis identifies a potential causal variant associated with lung adenocarcinoma risk in the Chinese population.
Mitochondrial CISD1/Cisd accumulation blocks mitophagy and genetic or pharmacological inhibition rescues neurodegenerative phenotypes in Pink1/parkin models.
Extracellular arginine availability modulates eIF2α O-GlcNAcylation and heme oxygenase 1 translation for cellular homeostasis.
Lin Q, Fan W, Chen Z, Chen B, Zhang C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Oct 15;39(19):e71083
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Oct 15;39(19):e71083
CISD2 ensures adequate ER-mitochondrial coupling, critically supporting mitochondrial function in neurons.
Loncke J, de Ridder I, La Rovere R, Vaarmann A, Fan G, Ahuja K, Serysheva I, Verfaillie C, Kerkhofs M, Parys JB, Kaasik A, Bultynck G, Vervliet T
Acta neuropathologica communications 2025 Nov 26;13(1):242
Acta neuropathologica communications 2025 Nov 26;13(1):242
ER calcium depletion as a key driver for impaired ER-to-mitochondria calcium transfer and mitochondrial dysfunction in Wolfram syndrome.
Liiv M, Vaarmann A, Safiulina D, Choubey V, Gupta R, Kuum M, Janickova L, Hodurova Z, Cagalinec M, Zeb A, Hickey MA, Huang YL, Gogichaishvili N, Mandel M, Plaas M, Vasar E, Loncke J, Vervliet T, Tsai TF, Bultynck G, Veksler V, Kaasik A
Nature communications 2024 Jul 21;15(1):6143
Nature communications 2024 Jul 21;15(1):6143
Integrating apaQTL and eQTL analysis identifies a potential causal variant associated with lung adenocarcinoma risk in the Chinese population.
Xu H, Wu Y, Chen Q, Yu Y, Meng Q, Qin N, Zhang W, Tao X, Li S, Tian T, Zhang L, Ma H, Cui J, Chu M
Communications biology 2024 Jul 13;7(1):860
Communications biology 2024 Jul 13;7(1):860
Mitochondrial CISD1/Cisd accumulation blocks mitophagy and genetic or pharmacological inhibition rescues neurodegenerative phenotypes in Pink1/parkin models.
Martinez A, Sanchez-Martinez A, Pickering JT, Twyning MJ, Terriente-Felix A, Chen PL, Chen CH, Whitworth AJ
Molecular neurodegeneration 2024 Jan 25;19(1):12
Molecular neurodegeneration 2024 Jan 25;19(1):12
Extracellular arginine availability modulates eIF2α O-GlcNAcylation and heme oxygenase 1 translation for cellular homeostasis.
Hung YW, Ouyang C, Ping X, Qi Y, Wang YC, Kung HJ, Ann DK
Journal of biomedical science 2023 May 22;30(1):32
Journal of biomedical science 2023 May 22;30(1):32
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- MCF7 cells were subjected to SDS PAGE followed by western blot with 66082-1-Ig(CISD2-Specific antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CISD2-Specific antibody from Proteintech is a mouse monoclonal antibody to a fusion protein of human CISD2-Specific. This antibody recognizes human antigen. The CISD2-Specific antibody has been validated for the following applications: ELISA, WB, IHC analysis.
