HPA029616

antibody from Atlas Antibodies

Targeting: DTNBP1 BLOC1S8, DBND, Dysbindin, HPS7, My031

Western blot (Enhanced validation)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

HPA029616

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA029616, RRID:AB_10602413

Product name

Anti-DTNBP1

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human DTNBP1, Gene description: dystrobrevin binding protein 1, Alternative Gene Names: BLOC1S8, DBND, Dysbindin, HPS7, My031, Validated applications: WB, IHC, Uniprot ID: Q96EV8, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.1 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

The Proteome of BLOC-1 Genetic Defects Identifies the Arp2/3 Actin Polymerization Complex to Function Downstream of the Schizophrenia Susceptibility Factor Dysbindin at the Synapse

Gokhale A, Hartwig C, Freeman A, Das R, Zlatic S, Vistein R, Burch A, Carrot G, Lewis A, Nelms S, Dickman D, Puthenveedu M, Cox D, Faundez V
The Journal of Neuroscience 2016;36(49):12393-12411

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TheN-Ethylmaleimide-Sensitive Factor and Dysbindin Interact To Modulate Synaptic Plasticity

Gokhale A, Mullin A, Zlatic S, Easley C, Merritt M, Raj N, Larimore J, Gordon D, Peden A, Sanyal S, Faundez V
The Journal of Neuroscience 2015;35(19):7643-7653

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Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells

Stadler C, Rexhepaj E, Singan V, Murphy R, Pepperkok R, Uhlén M, Simpson J, Lundberg E
Nature Methods 2013;10(4):315-323

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Quantitative Proteomic and Genetic Analyses of the Schizophrenia Susceptibility Factor Dysbindin Identify Novel Roles of the Biogenesis of Lysosome-Related Organelles Complex 1

Gokhale A, Larimore J, Werner E, So L, Moreno-De-Luca A, Lese-Martin C, Lupashin V, Smith Y, Faundez V
The Journal of Neuroscience 2012;32(11):3697-3711

Western blot

Enhanced validation

Submitted by

Atlas Antibodies (provider)

Enhanced method

Recombinant expression validation

Main image

Experimental details

Western blot analysis in control (vector only transfected HEK293T lysate) and DTNBP1 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY403167).

Sample type

Human

Protocol

Protocol