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ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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- Product number
- HPA038902 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA038902, RRID:AB_10674844
- Product name
- Anti-PPHLN1
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human PPHLN1, Gene description: periphilin 1, Validated applications: ICC, IHC, Uniprot ID: Q8NEY8, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.3 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references RNA binding by Periphilin plays an essential role in initiating silencing by the HUSH complex
Genome surveillance by HUSH-mediated silencing of intronless mobile elements
The HUSH complex is a gatekeeper of type I interferon through epigenetic regulation of LINE-1s
HIV-1 Vpr counteracts HLTF-mediated restriction of HIV-1 infection in T cells
Primate immunodeficiency virus proteins Vpx and Vpr counteract transcriptional repression of proviruses by the HUSH complex
Epigenetic silencing by the HUSH complex mediates position-effect variegation in human cells
Bloor S, Wit N, Lehner P
Nucleic Acids Research 2025;53(2)
Nucleic Acids Research 2025;53(2)
Genome surveillance by HUSH-mediated silencing of intronless mobile elements
Seczynska M, Bloor S, Cuesta S, Lehner P
Nature 2021;601(7893):440-445
Nature 2021;601(7893):440-445
The HUSH complex is a gatekeeper of type I interferon through epigenetic regulation of LINE-1s
Tunbak H, Enriquez-Gasca R, Tie C, Gould P, Mlcochova P, Gupta R, Fernandes L, Holt J, van der Veen A, Giampazolias E, Burns K, Maillard P, Rowe H
Nature Communications 2020;11(1)
Nature Communications 2020;11(1)
HIV-1 Vpr counteracts HLTF-mediated restriction of HIV-1 infection in T cells
Yan J, Shun M, Zhang Y, Hao C, Skowronski J
Proceedings of the National Academy of Sciences 2019;116(19):9568-9577
Proceedings of the National Academy of Sciences 2019;116(19):9568-9577
Primate immunodeficiency virus proteins Vpx and Vpr counteract transcriptional repression of proviruses by the HUSH complex
Yurkovetskiy L, Guney M, Kim K, Goh S, McCauley S, Dauphin A, Diehl W, Luban J
Nature Microbiology 2018;3(12):1354-1361
Nature Microbiology 2018;3(12):1354-1361
Epigenetic silencing by the HUSH complex mediates position-effect variegation in human cells
Tchasovnikarova I, Timms R, Matheson N, Wals K, Antrobus R, Göttgens B, Dougan G, Dawson M, Lehner P
Science 2015;348(6242):1481-1485
Science 2015;348(6242):1481-1485
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.
- Sample type
- Human
Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human testis and pancreas tissues using HPA038902 antibody. Corresponding PPHLN1 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
