Antibody data
- Antibody Data
- Antigen structure
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- Product number
- AMM01881G - Provider product page
- Provider
- Leading Biology
- Product name
- MTDH / Metadherin Antibody (clone 2F11C3)
- Antibody type
- Monoclonal
- Description
- Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF- kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance.
- Reactivity
- Human
- Host
- Mouse
- Antibody clone number
- 2F11C3
- Storage
- Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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