AMM01881G

antibody from Leading Biology

Targeting: MTDH 3D3, AEG-1, LYRIC

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

AMM01881G

Provider

Leading Biology

Product name

MTDH / Metadherin Antibody (clone 2F11C3)

Antibody type

Monoclonal

Description

Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF- kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance.

Reactivity

Human

Host

Mouse

Antibody clone number

2F11C3

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.