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ImmunoprecipitationAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Product number
- H00051185-B01P - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#H00051185-B01P, RRID:AB_2085740
- Product name
- Mouse Polyclonal CRBN Antibody
- Antibody type
- Polyclonal
- Description
- Protein A purified. CRBN - cereblon,
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.05 mg
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references The Neuroprotective Effect of Thalidomide against Ischemia through the Cereblon-mediated Repression of AMPK Activity.
CRL4A(CRBN) E3 ubiquitin ligase restricts BK channel activity and prevents epileptogenesis.
Deficient import of acetyl-CoA into the ER lumen causes neurodegeneration and propensity to infections, inflammation, and cancer.
Measuring cereblon as a biomarker of response or resistance to lenalidomide and pomalidomide requires use of standardized reagents and understanding of gene complexity.
Identification of salt-inducible kinase 3 as a novel tumor antigen associated with tumorigenesis of ovarian cancer.
Sawamura N, Yamada M, Fujiwara M, Yamada H, Hayashi H, Takagi N, Asahi T
Scientific reports 2018 Feb 6;8(1):2459
Scientific reports 2018 Feb 6;8(1):2459
CRL4A(CRBN) E3 ubiquitin ligase restricts BK channel activity and prevents epileptogenesis.
Liu J, Ye J, Zou X, Xu Z, Feng Y, Zou X, Chen Z, Li Y, Cang Y
Nature communications 2014 May 21;5:3924
Nature communications 2014 May 21;5:3924
Deficient import of acetyl-CoA into the ER lumen causes neurodegeneration and propensity to infections, inflammation, and cancer.
Peng Y, Li M, Clarkson BD, Pehar M, Lao PJ, Hillmer AT, Barnhart TE, Christian BT, Mitchell HA, Bendlin BB, Sandor M, Puglielli L
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 May 14;34(20):6772-89
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 May 14;34(20):6772-89
Measuring cereblon as a biomarker of response or resistance to lenalidomide and pomalidomide requires use of standardized reagents and understanding of gene complexity.
Gandhi AK, Mendy D, Waldman M, Chen G, Rychak E, Miller K, Gaidarova S, Ren Y, Wang M, Breider M, Carmel G, Mahmoudi A, Jackson P, Abbasian M, Cathers BE, Schafer PH, Daniel TO, Lopez-Girona A, Thakurta A, Chopra R
British journal of haematology 2014 Jan;164(2):233-44
British journal of haematology 2014 Jan;164(2):233-44
Identification of salt-inducible kinase 3 as a novel tumor antigen associated with tumorigenesis of ovarian cancer.
Charoenfuprasert S, Yang YY, Lee YC, Chao KC, Chu PY, Lai CR, Hsu KF, Chang KC, Chen YC, Chen LT, Chang JY, Leu SJ, Shih NY
Oncogene 2011 Aug 18;30(33):3570-84
Oncogene 2011 Aug 18;30(33):3570-84
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Supportive validation
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- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: CRBN Antibody [H00051185-B01P] - Analysis of CRBN expression in transfected 293T cell line by CRBN polyclonal antibody. Lane 1: CRBN transfected lysate(48.62 KDa). Lane 2: Non-transfected lysate.
