Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- ELISA [1]
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Validation data
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- Product number
- ABIN393257 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Potassium Voltage-Gated Channel, Isk-Related Family, Member 4 (KCNE4) (AA 1-171) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 1-171
- Isotype
- IgG
- Antibody clone number
- 1D7
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Germline genomic variants associated with childhood acute lymphoblastic leukemia.
KCNE4 suppresses Kv1.3 currents by modulating trafficking, surface expression and channel gating.
KCNE4 domains required for inhibition of KCNQ1.
KCNE4 can co-associate with the I(Ks) (KCNQ1-KCNE1) channel complex.
MiRP3 acts as an accessory subunit with the BK potassium channel.
Treviño LR, Yang W, French D, Hunger SP, Carroll WL, Devidas M, Willman C, Neale G, Downing J, Raimondi SC, Pui CH, Evans WE, Relling MV
Nature genetics 2009 Sep;41(9):1001-5
Nature genetics 2009 Sep;41(9):1001-5
KCNE4 suppresses Kv1.3 currents by modulating trafficking, surface expression and channel gating.
Solé L, Roura-Ferrer M, Pérez-Verdaguer M, Oliveras A, Calvo M, Fernández-Fernández JM, Felipe A
Journal of cell science 2009 Oct 15;122(Pt 20):3738-48
Journal of cell science 2009 Oct 15;122(Pt 20):3738-48
KCNE4 domains required for inhibition of KCNQ1.
Manderfield LJ, Daniels MA, Vanoye CG, George AL Jr
The Journal of physiology 2009 Jan 15;587(2):303-14
The Journal of physiology 2009 Jan 15;587(2):303-14
KCNE4 can co-associate with the I(Ks) (KCNQ1-KCNE1) channel complex.
Manderfield LJ, George AL Jr
The FEBS journal 2008 Mar;275(6):1336-49
The FEBS journal 2008 Mar;275(6):1336-49
MiRP3 acts as an accessory subunit with the BK potassium channel.
Levy DI, Wanderling S, Biemesderfer D, Goldstein SA
American journal of physiology. Renal physiology 2008 Aug;295(2):F380-7
American journal of physiology. Renal physiology 2008 Aug;295(2):F380-7
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- ELISA