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- Antibody Data
- Antigen structure
- References [23]
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- Validations
- Immunocytochemistry [1]
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- Product number
- 13573-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13573-1-AP, RRID:AB_10597396
- Product name
- TGN46 antibody
- Antibody type
- Polyclonal
- Description
- TGN46 antibody (Cat. #13573-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Cell death induced by nicotine in human neuroblastoma SH-SY5Y cells is mainly attributed to cytoplasmic vacuolation originating from the trans-Golgi network.
Reduction of DHHC5-mediated beclin 1 S-palmitoylation underlies autophagy decline in aging.
A conserved ion channel function of STING mediates noncanonical autophagy and cell death.
N-terminal acetyltransferase 6 facilitates enterovirus 71 replication by regulating PI4KB expression and replication organelle biogenesis.
CRISPR screens and lectin microarrays identify novel high mannose N-glycan regulators.
Immunofluorescence Microscopy of the Mammalian Golgi Apparatus.
Regulation of cellular cholesterol distribution via non-vesicular lipid transport at ER-Golgi contact sites.
The β Isoform of Human ATP-Binding Cassette B5 Transporter, ABCB5β, Localizes to the Endoplasmic Reticulum.
Presenilin 1 Modulates Acetylcholinesterase Trafficking and Maturation.
The Salmonella Typhimurium Effector SpvB Subverts Host Membrane Trafficking by Targeting Clathrin and AP-1.
SARS-CoV-2 protein ORF8 limits expression levels of Spike antigen and facilitates immune evasion of infected host cells.
Visualized procollagen Iα1 demonstrates the intracellular processing of propeptides.
Bunyavirus SFTSV exploits autophagic flux for viral assembly and egress.
Subcellular dynamics and functional activity of the cleaved intracellular domain of the Na(+) channel β1 subunit.
Identification of novel potential interaction partners of UDP-galactose (SLC35A2), UDP-N-acetylglucosamine (SLC35A3) and an orphan (SLC35A4) nucleotide sugar transporters.
GP73-mediated secretion of AFP and GP73 promotes proliferation and metastasis of hepatocellular carcinoma cells.
Oleate-induced aggregation of LC3 at the trans-Golgi network is linked to a protein trafficking blockade.
Live imaging of intra-lysosome pH in cell lines and primary neuronal culture using a novel genetically encoded biosensor.
Intracellular Group A Streptococcus Induces Golgi Fragmentation To Impair Host Defenses through Streptolysin O and NAD-Glycohydrolase.
Host RAB11FIP5 protein inhibits the release of Kaposi's sarcoma-associated herpesvirus particles by promoting lysosomal degradation of ORF45.
Novel Insights into Selected Disease-Causing Mutations within the SLC35A1 Gene Encoding the CMP-Sialic Acid Transporter.
Biowire Model of Interstitial and Focal Cardiac Fibrosis.
An Efficient Bivalent Cyclic RGD-PIK3CB siRNA Conjugate for Specific Targeted Therapy against Glioblastoma In Vitro and In Vivo.
Li J, Wang H, Chen H, Li X, Liu Y, Hou H, Hu Q
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Mar;185:114431
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Mar;185:114431
Reduction of DHHC5-mediated beclin 1 S-palmitoylation underlies autophagy decline in aging.
Guo R, Liu J, Min X, Zeng W, Shan B, Zhang M, He Z, Zhang Y, He K, Yuan J, Xu D
Nature structural & molecular biology 2024 Feb;31(2):232-245
Nature structural & molecular biology 2024 Feb;31(2):232-245
A conserved ion channel function of STING mediates noncanonical autophagy and cell death.
Xun J, Zhang Z, Lv B, Lu D, Yang H, Shang G, Tan JX
EMBO reports 2024 Feb;25(2):544-569
EMBO reports 2024 Feb;25(2):544-569
N-terminal acetyltransferase 6 facilitates enterovirus 71 replication by regulating PI4KB expression and replication organelle biogenesis.
Yang H, Fan T, Xun M, Wu B, Guo S, Li X, Zhao X, Yao H, Wang H
Journal of virology 2024 Feb 20;98(2):e0174923
Journal of virology 2024 Feb 20;98(2):e0174923
CRISPR screens and lectin microarrays identify novel high mannose N-glycan regulators.
Tsui CK, Twells N, Doan E, Woo J, Khosrojerdi N, Brooks J, Kulepa A, Webster B, Mahal LK, Dillin A
bioRxiv : the preprint server for biology 2024 Apr 10;
bioRxiv : the preprint server for biology 2024 Apr 10;
Immunofluorescence Microscopy of the Mammalian Golgi Apparatus.
Arab M, Nayak SC, Vitali T, Lowe M
Methods in molecular biology (Clifton, N.J.) 2023;2557:101-111
Methods in molecular biology (Clifton, N.J.) 2023;2557:101-111
Regulation of cellular cholesterol distribution via non-vesicular lipid transport at ER-Golgi contact sites.
Naito T, Yang H, Koh DHZ, Mahajan D, Lu L, Saheki Y
Nature communications 2023 Sep 21;14(1):5867
Nature communications 2023 Sep 21;14(1):5867
The β Isoform of Human ATP-Binding Cassette B5 Transporter, ABCB5β, Localizes to the Endoplasmic Reticulum.
Díaz-Anaya AM, Gerard L, Albert M, Gaussin JF, Boonen M, Gillet JP
International journal of molecular sciences 2023 Oct 31;24(21)
International journal of molecular sciences 2023 Oct 31;24(21)
Presenilin 1 Modulates Acetylcholinesterase Trafficking and Maturation.
Cortés-Gómez MÁ, Barberá VM, Alom J, Sáez-Valero J, García-Ayllón MS
International journal of molecular sciences 2023 Jan 11;24(2)
International journal of molecular sciences 2023 Jan 11;24(2)
The Salmonella Typhimurium Effector SpvB Subverts Host Membrane Trafficking by Targeting Clathrin and AP-1.
Yuan Y, Wang X, Jin J, Tang Z, Xian W, Zhang X, Fu J, He K, Liu X
Molecular & cellular proteomics : MCP 2023 Dec;22(12):100674
Molecular & cellular proteomics : MCP 2023 Dec;22(12):100674
SARS-CoV-2 protein ORF8 limits expression levels of Spike antigen and facilitates immune evasion of infected host cells.
Kim IJ, Lee YH, Khalid MM, Chen IP, Zhang Y, Ott M, Verdin E
The Journal of biological chemistry 2023 Aug;299(8):104955
The Journal of biological chemistry 2023 Aug;299(8):104955
Visualized procollagen Iα1 demonstrates the intracellular processing of propeptides.
Tanaka T, Moriya K, Tsunenaga M, Yanagawa T, Morita H, Minowa T, Tagawa YI, Hanagata N, Inagaki Y, Ikoma T
Life science alliance 2022 May;5(5)
Life science alliance 2022 May;5(5)
Bunyavirus SFTSV exploits autophagic flux for viral assembly and egress.
Yan JM, Zhang WK, Yan LN, Jiao YJ, Zhou CM, Yu XJ
Autophagy 2022 Jul;18(7):1599-1612
Autophagy 2022 Jul;18(7):1599-1612
Subcellular dynamics and functional activity of the cleaved intracellular domain of the Na(+) channel β1 subunit.
Haworth AS, Hodges SL, Capatina AL, Isom LL, Baumann CG, Brackenbury WJ
The Journal of biological chemistry 2022 Aug;298(8):102174
The Journal of biological chemistry 2022 Aug;298(8):102174
Identification of novel potential interaction partners of UDP-galactose (SLC35A2), UDP-N-acetylglucosamine (SLC35A3) and an orphan (SLC35A4) nucleotide sugar transporters.
Wiktor M, Wiertelak W, Maszczak-Seneczko D, Balwierz PJ, Szulc B, Olczak M
Journal of proteomics 2021 Oct 30;249:104321
Journal of proteomics 2021 Oct 30;249:104321
GP73-mediated secretion of AFP and GP73 promotes proliferation and metastasis of hepatocellular carcinoma cells.
Liu Y, Wang J, Yang R, Cheng Y, Zhou Y, Li H, Jiang W, Zhang X
Oncogenesis 2021 Oct 14;10(10):69
Oncogenesis 2021 Oct 14;10(10):69
Oleate-induced aggregation of LC3 at the trans-Golgi network is linked to a protein trafficking blockade.
Cerrato G, Leduc M, Müller K, Liu P, Zhao L, Humeau J, Xie W, Zhang S, Kepp O, Sauvat A, Kroemer G
Cell death and differentiation 2021 May;28(5):1733-1752
Cell death and differentiation 2021 May;28(5):1733-1752
Live imaging of intra-lysosome pH in cell lines and primary neuronal culture using a novel genetically encoded biosensor.
Ponsford AH, Ryan TA, Raimondi A, Cocucci E, Wycislo SA, Fröhlich F, Swan LE, Stagi M
Autophagy 2021 Jun;17(6):1500-1518
Autophagy 2021 Jun;17(6):1500-1518
Intracellular Group A Streptococcus Induces Golgi Fragmentation To Impair Host Defenses through Streptolysin O and NAD-Glycohydrolase.
Nozawa T, Iibushi J, Toh H, Minowa-Nozawa A, Murase K, Aikawa C, Nakagawa I
mBio 2021 Feb 9;12(1)
mBio 2021 Feb 9;12(1)
Host RAB11FIP5 protein inhibits the release of Kaposi's sarcoma-associated herpesvirus particles by promoting lysosomal degradation of ORF45.
Wei X, Dong J, Cheng CC, Ji M, Yu L, Luo S, Wu S, Bai L, Lan K
PLoS pathogens 2020 Dec;16(12):e1009099
PLoS pathogens 2020 Dec;16(12):e1009099
Novel Insights into Selected Disease-Causing Mutations within the SLC35A1 Gene Encoding the CMP-Sialic Acid Transporter.
Szulc B, Zadorozhna Y, Olczak M, Wiertelak W, Maszczak-Seneczko D
International journal of molecular sciences 2020 Dec 30;22(1)
International journal of molecular sciences 2020 Dec 30;22(1)
Biowire Model of Interstitial and Focal Cardiac Fibrosis.
Wang EY, Rafatian N, Zhao Y, Lee A, Lai BFL, Lu RX, Jekic D, Davenport Huyer L, Knee-Walden EJ, Bhattacharya S, Backx PH, Radisic M
ACS central science 2019 Jul 24;5(7):1146-1158
ACS central science 2019 Jul 24;5(7):1146-1158
An Efficient Bivalent Cyclic RGD-PIK3CB siRNA Conjugate for Specific Targeted Therapy against Glioblastoma In Vitro and In Vivo.
Cen B, Wei Y, Huang W, Teng M, He S, Li J, Wang W, He G, Bai X, Liu X, Yuan Y, Pan X, Ji A
Molecular therapy. Nucleic acids 2018 Dec 7;13:220-232
Molecular therapy. Nucleic acids 2018 Dec 7;13:220-232
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TGN46 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TGN46. This antibody recognizes human antigen. The TGN46 antibody has been validated for the following applications: ELISA, IF analysis.
