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- Product number
- CABT-BL8468 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Rabbit Anti-CDKN1B monoclonal antibody, clone TV48-15
- Antibody type
- Monoclonal
- Description
- Cell cycle progression is regulated by a series of cyclin-dependent kinases consisting of catalytic subunits, designated Cdks, as well as activating subunits, designated cyclins. Orderly progression through the cell cycle requires the activation and inactivation of different cyclin-Cdks at appropriate times. A series of proteins has recently been described that function as "mitotic inhibitors." These include p21, the levels of which are elevated upon DNA damage in G1 in a p53-dependent manner
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