14583-1-AP

antibody from Proteintech Group

Targeting: RPL7 humL7-1, L7

Provider product page for 14583-1-AP

Western blot

ELISA

Immunocytochemistry

Immunoprecipitation

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [17]
Comments [0]
Validations
Western blot [1]
Immunohistochemistry [2]

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Product number: 14583-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#14583-1-AP, RRID:AB_2254049
Product name: RPL7 antibody
Antibody type: Polyclonal
Description: RPL7 antibody (Cat. #14583-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

RPL7 protein structure - 14583-1-AP shown in red.

Submitted references Eukaryote initiation factor 6 modulates small-cell lung carcinoma plasticity via the integrin-FAK signaling axis.

Peng H, Wang Z, Wang M, Ding Z, Li K, Wang Y, Yu X, Song S, Deng Y, Liu Y, Pu Q, Li L, Cerezo M, Wang W, Liu L, Shen S
Nature communications 2026 Feb 24;17(1)

Mathematical modeling of ribosome competition informs testable treatment strategies for drug-tolerant cancer persister cells.

Tang X, Wang Y, Pu Y, Li K, Ding Z, Wang M, Almeida L, Cerezo M, Cao Y, Robert C, Peurichard D, Shen S
iScience 2026 Apr 17;29(4):115493

rRNA expansion segments mediate ribosome dimerization as a conserved stress response.

Jiang W, Chen C, Wang X, Huang W, Krokowski D, Chen Z, Xie J, Su Z, Hatzoglou M, Taylor DJ, Guo Q
Nucleic acids research 2026 Apr 13;54(7)

Rpl12 is a conserved ribophagy receptor.

Chen Y, Hu J, Zhao P, Fang J, Kuang Y, Liu Z, Dong S, Yao W, Ding Y, Wang X, Pan Y, Wu J, Zhao J, Yang J, Xu Z, Liu X, Zhang Y, Wu C, Zhang L, Fan M, Feng S, Hong Z, Yan Z, Xia H, Tang K, Yang B, Liu W, Sun Q, Mei K, Zou W, Huang Y, Feng D, Yi C
Nature cell biology 2025 Mar;27(3):477-492

Adipocyte-derived glutathione promotes obesity-related breast cancer by regulating the SCARB2-ARF1-mTORC1 complex.

Zhao C, Zhang T, Xue ST, Zhang P, Wang F, Li Y, Liu Y, Zhao L, Wu J, Yan Y, Mao X, Chen Y, Yuan J, Li Z, Li K
Cell metabolism 2025 Mar 4;37(3):692-707.e9

Ribosome-binding protein 1 maintains peroxisome biogenesis.

Fatima K, Vihinen H, Akpinar A, Somborac T, Paatero A, Jokitalo E, Paavilainen V, Katajisto P, Konovalova S
Journal of cell science 2025 Dec 15;138(24)

Nucleolin lactylation contributes to intrahepatic cholangiocarcinoma pathogenesis via RNA splicing regulation of MADD.

Yang L, Niu K, Wang J, Shen W, Jiang R, Liu L, Song W, Wang X, Zhang X, Zhang R, Wei D, Fan M, Jia L, Tao K
Journal of hepatology 2024 Oct;81(4):651-666

E3 ubiquitin ligase RNF10 promotes dissociation of stalled ribosomes and responds to ribosomal subunit imbalance.

Lehmann JA, Lindner D, Sung HM, Stoecklin G
Nature communications 2024 Nov 28;15(1):10350

Puromycin reveals a distinct conformation of neuronal ribosomes.

Anadolu MN, Sun J, Li JT, Graber TE, Ortega J, Sossin WS
Proceedings of the National Academy of Sciences of the United States of America 2024 Feb 13;121(7):e2306993121

METTL16 promotes liver cancer stem cell self-renewal via controlling ribosome biogenesis and mRNA translation.

Xue M, Dong L, Zhang H, Li Y, Qiu K, Zhao Z, Gao M, Han L, Chan AKN, Li W, Leung K, Wang K, Pokharel SP, Qing Y, Liu W, Wang X, Ren L, Bi H, Yang L, Shen C, Chen Z, Melstrom L, Li H, Timchenko N, Deng X, Huang W, Rosen ST, Tian J, Xu L, Diao J, Chen CW, Chen J, Shen B, Chen H, Su R
Journal of hematology & oncology 2024 Feb 1;17(1):7

Detection of ribophagy in yeast and mammals.

Ye M, Chen Y, Liu Z, Wang Y, Yi C
Biophysics reports 2024 Apr 30;10(2):82-101

QKI shuttles internal m(7)G-modified transcripts into stress granules and modulates mRNA metabolism.

Zhao Z, Qing Y, Dong L, Han L, Wu D, Li Y, Li W, Xue J, Zhou K, Sun M, Tan B, Chen Z, Shen C, Gao L, Small A, Wang K, Leung K, Zhang Z, Qin X, Deng X, Xia Q, Su R, Chen J
Cell 2023 Jul 20;186(15):3208-3226.e27

Glucose controls co-translation of structurally related mRNAs via the mTOR and eIF2 pathways in human pancreatic beta cells.

Bulfoni M, Bouyioukos C, Zakaria A, Nigon F, Rapone R, Del Maestro L, Ait-Si-Ali S, Scharfmann R, Cosson B
Frontiers in endocrinology 2022;13:949097

METTL16 exerts an m(6)A-independent function to facilitate translation and tumorigenesis.

Su R, Dong L, Li Y, Gao M, He PC, Liu W, Wei J, Zhao Z, Gao L, Han L, Deng X, Li C, Prince E, Tan B, Qing Y, Qin X, Shen C, Xue M, Zhou K, Chen Z, Xue J, Li W, Qin H, Wu X, Sun M, Nam Y, Chen CW, Huang W, Horne D, Rosen ST, He C, Chen J
Nature cell biology 2022 Feb;24(2):205-216

Endosomal lipid signaling reshapes the endoplasmic reticulum to control mitochondrial function.

Jang W, Puchkov D, Samsó P, Liang Y, Nadler-Holly M, Sigrist SJ, Kintscher U, Liu F, Mamchaoui K, Mouly V, Haucke V
Science (New York, N.Y.) 2022 Dec 16;378(6625):eabq5209

Local translation in nuclear condensate amyloid bodies.

Theodoridis PR, Bokros M, Marijan D, Balukoff NC, Wang D, Kirk CC, Budine TD, Goldsmith HD, Wang M, Audas TE, Lee S
Proceedings of the National Academy of Sciences of the United States of America 2021 Feb 16;118(7)

CRISPR-based RNA-binding protein mapping in live cells.

Chen B, Shi H, Zhang J, Zhou C, Han M, Jiang W, Lai Y, Tu X, Li H
Biochemical and biophysical research communications 2021 Dec 17;583:79-85

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: HEK-293 cells were subjected to SDS PAGE followed by western blot with 14583-1-AP(RPL7 antibody) at dilution of 1:1500
Sample type: cell line

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The RPL7 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human RPL7. This antibody recognizes human, mouse, rat antigen. The RPL7 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
Appendix: 14583-1-AP.pdf

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunohistochemical of paraffin-embedded human skin cancer using 14583-1-AP(RPL7 antibody) at dilution of 1:100 (under 10x lens)
Sample type: tissue