Tissue expression
Cell line expression
Protein structure
NFX1
Nuclear transcription factor, X-box binding 1MGC20369, NFX2, TEG-42, Tex42
MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. The protein encoded by this gene is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma. Three alternative splice variants, each of which encodes a different isoform, have been identified. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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antibodies-online | ABIN394031 | Monoclonal |
WB
EL
ICC
IHC |
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Novus Biologicals | H00004799-M01 | Monoclonal |
WB
EL
ICC
|
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Abnova Corporation | H00004799-M01 | Monoclonal |
WB
EL
ICC
|
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LSBio | LS-C197777 | Monoclonal |
WB
EL
ICC
|
||
Abgent | AT3039a | Monoclonal |
WB
EL
ICC
|
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Supportive data in Antibodypedia
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