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- References [11]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 11268-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11268-1-AP, RRID:AB_10638004
- Product name
- NELL2 antibody
- Antibody type
- Polyclonal
- Description
- NELL2 antibody (Cat. #11268-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Comprehensive analysis of basement membrane-related genes showed that NELL2 is a new therapeutic target for colorectal cancer.
Chemical Synthesis of NICOL, A Coligand Secreted Protein Mediating Mammalian Male Reproductive Tract Trans-luminal Signaling.
Bioinformatics Analysis Reveals a Novel Prognostic Model for Esophageal Squamous Cell Carcinoma.
Expression of NELL2/NICOL-ROS1 lumicrine signaling-related molecules in the human male reproductive tract.
Single-cell profiling of the microenvironment in human bone metastatic renal cell carcinoma.
A small secreted protein NICOL regulates lumicrine-mediated sperm maturation and male fertility.
Single-cell transcriptomic profiling unravels the adenoma-initiation role of protein tyrosine kinases during colorectal tumorigenesis.
An Extracellular Matrix-Based Signature Associated With Immune Microenvironment Predicts the Prognosis and Therapeutic Responses of Patients With Oesophageal Squamous Cell Carcinoma.
microRNA‑196a‑3p inhibits cell proliferation and promotes cell apoptosis by targeting ADP ribosylation factor 4 in diffuse large B‑cell lymphoma.
Vincristine Impairs Microtubules and Causes Neurotoxicity in Cerebral Organoids.
Tranylcypromine Causes Neurotoxicity and Represses BHC110/LSD1 in Human-Induced Pluripotent Stem Cell-Derived Cerebral Organoids Model.
Wang W, Dai Z, Ge C, Zhou X, Zhan Y, Chen C
Discover oncology 2025 Feb 17;16(1):195
Discover oncology 2025 Feb 17;16(1):195
Chemical Synthesis of NICOL, A Coligand Secreted Protein Mediating Mammalian Male Reproductive Tract Trans-luminal Signaling.
Nagahama K, Takei T, Ito S, Takao T, Hojo H, Kiyozumi D
Chemistry (Weinheim an der Bergstrasse, Germany) 2025 Aug 21;31(47):e01588
Chemistry (Weinheim an der Bergstrasse, Germany) 2025 Aug 21;31(47):e01588
Bioinformatics Analysis Reveals a Novel Prognostic Model for Esophageal Squamous Cell Carcinoma.
Yang H, Chen Y, Huang X, Gu Y, Chen Z, Mao W
International journal of medical sciences 2024;21(7):1213-1226
International journal of medical sciences 2024;21(7):1213-1226
Expression of NELL2/NICOL-ROS1 lumicrine signaling-related molecules in the human male reproductive tract.
Kiyozumi D
Reproductive biology and endocrinology : RB&E 2024 Jan 2;22(1):3
Reproductive biology and endocrinology : RB&E 2024 Jan 2;22(1):3
Single-cell profiling of the microenvironment in human bone metastatic renal cell carcinoma.
Ma F, Wang S, Xu L, Huang W, Shi G, Sun Z, Cai W, Wu Z, Huang Y, Meng J, Sun Y, Fang M, Cheng M, Ji Y, Hu T, Zhang Y, Gu B, Zhang J, Song S, Sun Y, Yan W
Communications biology 2024 Jan 12;7(1):91
Communications biology 2024 Jan 12;7(1):91
A small secreted protein NICOL regulates lumicrine-mediated sperm maturation and male fertility.
Kiyozumi D, Shimada K, Chalick M, Emori C, Kodani M, Oura S, Noda T, Endo T, Matzuk MM, Wreschner DH, Ikawa M
Nature communications 2023 Apr 24;14(1):2354
Nature communications 2023 Apr 24;14(1):2354
Single-cell transcriptomic profiling unravels the adenoma-initiation role of protein tyrosine kinases during colorectal tumorigenesis.
Zheng X, Song J, Yu C, Zhou Z, Liu X, Yu J, Xu G, Yang J, He X, Bai X, Luo Y, Bao Y, Li H, Yang L, Xu M, Song N, Su X, Xu J, Ma X, Shi H
Signal transduction and targeted therapy 2022 Feb 28;7(1):60
Signal transduction and targeted therapy 2022 Feb 28;7(1):60
An Extracellular Matrix-Based Signature Associated With Immune Microenvironment Predicts the Prognosis and Therapeutic Responses of Patients With Oesophageal Squamous Cell Carcinoma.
Zhang H, Shi Q, Yang Z, Wang K, Zhang Z, Huang Z, Cui X, Li F
Frontiers in molecular biosciences 2021;8:598427
Frontiers in molecular biosciences 2021;8:598427
microRNA‑196a‑3p inhibits cell proliferation and promotes cell apoptosis by targeting ADP ribosylation factor 4 in diffuse large B‑cell lymphoma.
Fu J, Lou X, Wan S, Zhao X, Chen Z, Zhu M, Guo L, Wu D, Wang S
Oncology reports 2021 Feb;45(2):764-775
Oncology reports 2021 Feb;45(2):764-775
Vincristine Impairs Microtubules and Causes Neurotoxicity in Cerebral Organoids.
Liu F, Huang J, Liu Z
Neuroscience 2019 Apr 15;404:530-540
Neuroscience 2019 Apr 15;404:530-540
Tranylcypromine Causes Neurotoxicity and Represses BHC110/LSD1 in Human-Induced Pluripotent Stem Cell-Derived Cerebral Organoids Model.
Huang J, Liu F, Tang H, Wu H, Li L, Wu R, Zhao J, Wu Y, Liu Z, Chen J
Frontiers in neurology 2017;8:626
Frontiers in neurology 2017;8:626
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 11268-1-AP(NELL2 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon cancer using 11268-1-AP(NELL2 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The NELL2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human NELL2. This antibody recognizes human,mouse,rat antigen. The NELL2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
