ADORA2B

This gene encodes an adenosine receptor that is a member of the G protein-coupled receptor superfamily. This integral membrane protein stimulates adenylate cyclase activity in the presence of adenosine. This protein also interacts with netrin-1, which is involved in axon elongation. The gene is located near the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]

Description

adenosine A2b receptor

Protein family

FDA approved drug targets, G-protein coupled receptors, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted membrane proteins, Protein evidence (Peptideatlas)

Chromosome

17:p12 (15944917 - 15975746)

Ensembl ID

ENSG00000170425  (ver. 99.38)

Orthologs

Mouse Adora2b: ENSMUSG00000018500

UniProt

P29275

neXtProt

NX_P29275

Human splice variants
Mouse splice variants