Antibody data
- Antibody Data
- Antigen structure
- References [22]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 18475-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18475-1-AP, RRID:AB_2248812
- Product name
- ID1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ID1 antibody (Cat. #18475-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references ZDHHC2-Dependent Palmitoylation Dictates Ferroptosis and Castration Sensitivity in Prostate Cancer via Controlling ACSL4 Degradation and Lipid Peroxidation.
The METTL3-IGF2BP3 axis drives osteosarcoma progression by enhancing ID1 mRNA stability.
KDM4A-driven SMAD5/TGFβ axis activation as a therapeutic target in cholangiocarcinoma: mechanistic insights and translational implications.
ANG secretion predisposes endothelial cells toward angiogenesis in FIN56-induced ferroptotic hepatocellular carcinoma via the BMP6/ID1 signaling pathway.
A single-cell transcriptomic atlas of human lens epithelium: identification and functional insights into lens stem/progenitor cells.
Noggin Combined With Human Dental Pulp Stem Cells to Promote Skeletal Muscle Regeneration.
ID1 expressing macrophages support cancer cell stemness and limit CD8(+) T cell infiltration in colorectal cancer.
Palovarotene Can Attenuate Heterotopic Ossification Induced by Tendon Stem Cells by Downregulating the Synergistic Effects of Smad and NF-κB Signaling Pathway following Stimulation of the Inflammatory Microenvironment.
Functions of retinal astrocytes and Müller cells in mammalian myopia.
The miR-182/Myadm axis regulates hypoxia-induced pulmonary hypertension by balancing the BMP- and TGF-β-signalling pathways in an SMC/EC-crosstalk-associated manner.
Pantoprazole ameliorates liver fibrosis and suppresses hepatic stellate cell activation in bile duct ligation rats by promoting YAP degradation.
Ursodesoxycholic acid alleviates liver fibrosis via proregeneration by activation of the ID1-WNT2/HGF signaling pathway.
Endothelial progenitor cells as critical mediators of environmental air pollution-induced cardiovascular toxicity.
IL-1β Promotes Stemness of Tumor Cells by Activating Smad/ID1 Signaling Pathway.
Exosomal miR-125a-5p derived from silica-exposed macrophages induces fibroblast transdifferentiation.
Expansion and maintenance of primary corneal epithelial stem/progenitor cells by inhibition of TGFβ receptor I-mediated signaling.
Defining multistep cell fate decision pathways during pancreatic development at single-cell resolution.
Id1/NR2B Receptor Pathway Regulates Rat Cochlear Sensory Epithelial Cell Survival after Radiation.
High extracellular pressure promotes gastric cancer cell adhesion, invasion, migration and suppresses gastric cancer cell differentiation.
BMP-6 inhibits cell proliferation by targeting microRNA-192 in breast cancer.
Bone morphogenetic protein 4, inhibitor of differentiation 1, and epidermal growth factor receptor regulate the survival of cochlear sensory epithelial cells.
Exposure to ambient air fine particulate matter prevents VEGF-induced mobilization of endothelial progenitor cells from the bone marrow.
Shao S, Li W, Hong Y, Zeng R, Zhu L, Yi L, Li Y, Wang Y, Huang H, Jiang X, Jin X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(1):e14077
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(1):e14077
The METTL3-IGF2BP3 axis drives osteosarcoma progression by enhancing ID1 mRNA stability.
Shu R, Cheng Q, Yu Z, Zhou H, Lin M, Shi M, Chen J, Chen J, Zhao M
BMC musculoskeletal disorders 2026 Jan 30;27(1)
BMC musculoskeletal disorders 2026 Jan 30;27(1)
KDM4A-driven SMAD5/TGFβ axis activation as a therapeutic target in cholangiocarcinoma: mechanistic insights and translational implications.
Wang Q, Kuai Y, Xiong F, Wang D, Wu G, Liu W, Chen J, Wang B, Chen Y
Cell & bioscience 2025 Sep 29;15(1):128
Cell & bioscience 2025 Sep 29;15(1):128
ANG secretion predisposes endothelial cells toward angiogenesis in FIN56-induced ferroptotic hepatocellular carcinoma via the BMP6/ID1 signaling pathway.
Liu X, Long G, Wang Q, Wang J, Chen X, Zhou Y, You K, Li H, Jiang Y, Zhang Z, Du X, Han Y
Free radical biology & medicine 2025 Oct;238:17-35
Free radical biology & medicine 2025 Oct;238:17-35
A single-cell transcriptomic atlas of human lens epithelium: identification and functional insights into lens stem/progenitor cells.
Gu Y, Chen L, Chen S, Wu Y, Hao S, Sheng F, Yuan J, Qin Z, Wu D, Han Y, Yao Z, Chen Z, Wormstone IM, Yu Y, Qian J, Fu Q, Yao K
Stem cell research & therapy 2025 Jul 1;16(1):333
Stem cell research & therapy 2025 Jul 1;16(1):333
Noggin Combined With Human Dental Pulp Stem Cells to Promote Skeletal Muscle Regeneration.
Zhang MH, Yu LM, Zhang WH, Deng JJ, Sun BJ, Chen MH, Huang W, Li J, He H, Han XX, Liu YH
Stem cells international 2024;2024:2812390
Stem cells international 2024;2024:2812390
ID1 expressing macrophages support cancer cell stemness and limit CD8(+) T cell infiltration in colorectal cancer.
Shang S, Yang C, Chen F, Xiang RS, Zhang H, Dai SY, Liu J, Lv XX, Zhang C, Liu XT, Zhang Q, Lu SB, Song JW, Yu JJ, Zhou JC, Zhang XW, Cui B, Li PP, Zhu ST, Zhang HZ, Hua F
Nature communications 2023 Nov 23;14(1):7661
Nature communications 2023 Nov 23;14(1):7661
Palovarotene Can Attenuate Heterotopic Ossification Induced by Tendon Stem Cells by Downregulating the Synergistic Effects of Smad and NF-κB Signaling Pathway following Stimulation of the Inflammatory Microenvironment.
Huang J, Lin J, Li C, Tang B, Xiao H
Stem cells international 2022;2022:1560943
Stem cells international 2022;2022:1560943
Functions of retinal astrocytes and Müller cells in mammalian myopia.
Zhang X, Yu X, Wen Y, Jin L, Zhang L, Zhu H, Zhang D, Xie C, Guo D, Tong J, Shen Y
BMC ophthalmology 2022 Nov 24;22(1):451
BMC ophthalmology 2022 Nov 24;22(1):451
The miR-182/Myadm axis regulates hypoxia-induced pulmonary hypertension by balancing the BMP- and TGF-β-signalling pathways in an SMC/EC-crosstalk-associated manner.
Bai Y, Wang J, Chen Y, Lv T, Wang X, Liu C, Xue H, He K, Sun L
Basic research in cardiology 2021 Sep 21;116(1):53
Basic research in cardiology 2021 Sep 21;116(1):53
Pantoprazole ameliorates liver fibrosis and suppresses hepatic stellate cell activation in bile duct ligation rats by promoting YAP degradation.
Lu ZN, Niu WX, Zhang N, Ge MX, Bao YY, Ren Y, Guo XL, He HW
Acta pharmacologica Sinica 2021 Nov;42(11):1808-1820
Acta pharmacologica Sinica 2021 Nov;42(11):1808-1820
Ursodesoxycholic acid alleviates liver fibrosis via proregeneration by activation of the ID1-WNT2/HGF signaling pathway.
Dong X, Luo Y, Lu S, Ma H, Zhang W, Zhu Y, Sun G, Sun X
Clinical and translational medicine 2021 Feb;11(2):e296
Clinical and translational medicine 2021 Feb;11(2):e296
Endothelial progenitor cells as critical mediators of environmental air pollution-induced cardiovascular toxicity.
Singh P, O'Toole TE, Conklin DJ, Hill BG, Haberzettl P
American journal of physiology. Heart and circulatory physiology 2021 Apr 1;320(4):H1440-H1455
American journal of physiology. Heart and circulatory physiology 2021 Apr 1;320(4):H1440-H1455
IL-1β Promotes Stemness of Tumor Cells by Activating Smad/ID1 Signaling Pathway.
Lu L, Wang P, Zou Y, Zha Z, Huang H, Guan M, Wu Y, Liu G
International journal of medical sciences 2020;17(9):1257-1268
International journal of medical sciences 2020;17(9):1257-1268
Exosomal miR-125a-5p derived from silica-exposed macrophages induces fibroblast transdifferentiation.
Wang D, Hao C, Zhang L, Zhang J, Liu S, Li Y, Qu Y, Zhao Y, Huang R, Wei J, Yao W
Ecotoxicology and environmental safety 2020 Apr 1;192:110253
Ecotoxicology and environmental safety 2020 Apr 1;192:110253
Expansion and maintenance of primary corneal epithelial stem/progenitor cells by inhibition of TGFβ receptor I-mediated signaling.
Hu L, Pu Q, Zhang Y, Ma Q, Li G, Li X
Experimental eye research 2019 May;182:44-56
Experimental eye research 2019 May;182:44-56
Defining multistep cell fate decision pathways during pancreatic development at single-cell resolution.
Yu XX, Qiu WL, Yang L, Zhang Y, He MY, Li LC, Xu CR
The EMBO journal 2019 Apr 15;38(8)
The EMBO journal 2019 Apr 15;38(8)
Id1/NR2B Receptor Pathway Regulates Rat Cochlear Sensory Epithelial Cell Survival after Radiation.
Chen J, Zhou X, Zou T, Wang B, Yu Y, Lin F, Chen K, Lai Y, Sun K
Audiology & neuro-otology 2018;23(3):173-180
Audiology & neuro-otology 2018;23(3):173-180
High extracellular pressure promotes gastric cancer cell adhesion, invasion, migration and suppresses gastric cancer cell differentiation.
Su C, Zhang B, Liu W, Zheng H, Sun L, Tong J, Wang T, Jiang X, Liang H, Xue L, Zhang Q
Oncology reports 2016 Aug;36(2):1048-54
Oncology reports 2016 Aug;36(2):1048-54
BMP-6 inhibits cell proliferation by targeting microRNA-192 in breast cancer.
Hu F, Meng X, Tong Q, Liang L, Xiang R, Zhu T, Yang S
Biochimica et biophysica acta 2013 Dec;1832(12):2379-90
Biochimica et biophysica acta 2013 Dec;1832(12):2379-90
Bone morphogenetic protein 4, inhibitor of differentiation 1, and epidermal growth factor receptor regulate the survival of cochlear sensory epithelial cells.
Chen J, Sun W, Zheng Y, Xiong H, Cai Y
Journal of neuroscience research 2013 Apr;91(4):515-26
Journal of neuroscience research 2013 Apr;91(4):515-26
Exposure to ambient air fine particulate matter prevents VEGF-induced mobilization of endothelial progenitor cells from the bone marrow.
Haberzettl P, Lee J, Duggineni D, McCracken J, Bolanowski D, O'Toole TE, Bhatnagar A, Conklin DJ
Environmental health perspectives 2012 Jun;120(6):848-56
Environmental health perspectives 2012 Jun;120(6):848-56
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The ID1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ID1. This antibody recognizes human, mouse, rat antigen. The ID1 antibody has been validated for the following applications: ELISA, WB analysis.