SLC9A7

This gene encodes a sodium and potassium/ proton antiporter that is a member of the solute carrier family 9 protein family. The encoded protein is primarily localized to the trans-Golgi network and is involved in maintaining pH homeostasis in organelles along the secretory and endocytic pathways. This protein may enhance cell growth of certain breast tumors. This gene is part of a gene cluster on chromosome Xp11.23. A pseudogene of this gene is found on chromosome 12. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012]

Description

Solute carrier family 9 member A7

Tissue specificity

Tissue enriched (brain)

Subcell location

Vesicles

Predicted location

Membrane

Protein family

Disease related genes
Human disease related genes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Plasma proteins
Potential drug targets
Predicted membrane proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)
Transporters

Chromosome

X (46599251 - 46759118)

Ensembl ID

ENSG00000065923  (ver. 103.38)

Orthologs

Mouse Slc9a7: ENSMUSG00000037341

UniProt

Q96T83

neXtProt

NX_Q96T83

Human splice variants
Mouse splice variants

Protein structure