25874-1-AP

antibody from Proteintech Group

Targeting: HKDC1 FLJ22761, FLJ37767

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunoprecipitation (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

25874-1-AP

Provider

Proteintech Group

Product name

HKDC1 antibody

Antibody type

Polyclonal

Description

HKDC1 antibody (Cat. #25874-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, IP, WB,ELISA.

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

HKDC1 promotes the H3K18 lactylation of the promoter of ORMDL3 to induce the activation of hepatic stellate cells in liver cirrhosis.

Zhang Y, Li L, Li G, Zhu J, Qi Z, Zhang C
Biochimica et biophysica acta. Molecular basis of disease 2026 Mar;1872(3):168140

---

HNF4α-HKDC1 axis orchestrates a metabolic rewiring to promote migration and metastasis in advanced gastric cancer.

Xu X, Wu H, Shang J, Wang Y, Yang Y, Cai T, Chen L, Xu X, Zhang C, Zhang W, Wang D, Zhang M, Zhan YY
Cell death & disease 2026 Mar 23;17(1)

---

p53-induced RNA-binding protein ZMAT3 inhibits transcription of a hexokinase to suppress mitochondrial respiration in human cancer cells.

Kumar R, Couly S, Muys BR, Li XL, Grammatikakis I, Singh R, Guest M, Wen X, Tang W, Ambs S, Jenkins LM, Pehrsson EC, Chari R, Su TP, Lal A
eLife 2026 Mar 17;14

---

Menin regulates YBX1 nucleus translocation to boost the HKDC1 transcription and affects pancreatic cancer glycolysis.

Ni C, Yang J, Lu Y, Ma H, Hu H, Shi X, He T, Zhang Y, Jin G, Cheng P
iScience 2025 Sep 19;28(9):113245

---

p53-induced RNA-binding protein ZMAT3 inhibits transcription of a hexokinase to suppress mitochondrial respiration.

Kumar R, Couly S, Muys BR, Li XL, Grammatikakis I, Singh R, Guest M, Wen X, Tang W, Ambs S, Jenkins LM, Pehrsson EC, Chari R, Su TP, Lal A
bioRxiv : the preprint server for biology 2025 May 13;

---

Nuclear-localized HKDC1 promotes hepatocellular carcinoma through phosphorylating RBBP5 to upregulate H3K4me3.

Ye L, Shen S, Mao Q, Lu H, Liu H, Zhang P, Jiang Z, Ma W, Sun Y, Chu Y, Zhou Z, Liu R, Li J, Li ST, Gao P, Zhang H
Cell reports 2025 Feb 25;44(2):115250

---

HKDC1 promotes ovarian cancer progression through boosting lipid metabolism and immune escape by stabilizing G6PC/G6PC2.

Wang Y, Chen J, Wang Z, Luo X, Wu N, Wang J
Communications biology 2025 Apr 16;8(1):615

---

HKDC1 enhances the proliferation, migration and glycolysis of pancreatic adenocarcinoma and is linked to immune infiltration.

Pang Q, Huang S, Cao J
Journal of Cancer 2024;15(7):1983-1993

---

Mechano-induced arachidonic acid metabolism promotes keratinocyte proliferation through cPLA2 activity regulation.

Shan S, Jin R, Cheng X, He J, Luo X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Dec 15;38(23):e70226

---

New insights into the treatment of polycystic ovary syndrome: HKDC1 promotes the growth of ovarian granulocyte cells by regulating mitochondrial function and glycolysis.

Cong P, Shang B, Zhang L, Wu Z, Wang Y, Li J, Zhang L
Journal of molecular histology 2024 Apr;55(2):187-199

---

Mitochondria-Related Transcriptome Characterization Associated with the Immune Microenvironment, Therapeutic Response and Survival Prediction in Pancreatic Cancer.

Dong J, Liu J, Zhang B, Liang C, Hua J, Meng Q, Wei M, Wang W, Yu X, Xu J
International journal of molecular sciences 2023 Feb 7;24(4)

---

Establishment and characterization of a new cell culture system for hepatitis B virus replication and infection.

Song Y, Shou S, Guo H, Gao Z, Liu N, Yang Y, Wang F, Deng Q, Liu J, Xie Y
Virologica Sinica 2022 Aug;37(4):558-568