Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 17947-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17947-1-AP, RRID:AB_10644486
- Product name
- RGN/SMP30 antibody
- Antibody type
- Polyclonal
- Description
- RGN/SMP30 antibody (Cat. #17947-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Proteomic analysis reveals the aging-related pathways contribute to pulmonary fibrogenesis.
Hexavalent chromium triggers hepatocytes premature senescence via the GATA4/NF-κB signaling pathway mediated by the DNA damage response.
Identification and functional analysis of senescence-associated secretory phenotype of premature senescent hepatocytes induced by hexavalent chromium.
Senescence marker protein 30 (SMP30) protects against high glucose-induced apoptosis, oxidative stress and inflammatory response in retinal ganglion cells by enhancing Nrf2 activation via regulation of Akt/GSK-3β pathway.
Senescence marker protein 30 inhibits tumor growth by reducing HDAC4 expression in non-small cell lung cancer.
Intron retention as a new pre-symptomatic marker of aging and its recovery to the normal state by a traditional Japanese multi-herbal medicine.
Exogenous regucalcin negatively regulates the progression of cervical adenocarcinoma.
A mechanism of regucalcin knock-down in the promotion of proliferation and movement of human cervical cancer HeLa cells.
Hepatic thyroid signaling of heat-stressed late pregnant and early lactating cows.
Dioscin, a natural steroid saponin, shows remarkable protective effect against acetaminophen-induced liver damage in vitro and in vivo.
Zhang T, Yuan X, Jiang M, Liu B, Zhai N, Zhang Q, Song X, Lv C, Zhang J, Li H
Aging 2023 Dec 22;15(24):15382-15401
Aging 2023 Dec 22;15(24):15382-15401
Hexavalent chromium triggers hepatocytes premature senescence via the GATA4/NF-κB signaling pathway mediated by the DNA damage response.
Ma Y, Li S, Ye S, Hu D, Wei L, Xiao F
Ecotoxicology and environmental safety 2022 Jul 1;239:113645
Ecotoxicology and environmental safety 2022 Jul 1;239:113645
Identification and functional analysis of senescence-associated secretory phenotype of premature senescent hepatocytes induced by hexavalent chromium.
Ma Y, Liang Y, Liang N, Zhang Y, Xiao F
Ecotoxicology and environmental safety 2021 Mar 15;211:111908
Ecotoxicology and environmental safety 2021 Mar 15;211:111908
Senescence marker protein 30 (SMP30) protects against high glucose-induced apoptosis, oxidative stress and inflammatory response in retinal ganglion cells by enhancing Nrf2 activation via regulation of Akt/GSK-3β pathway.
Zhang L, Zhu T, He F, Li X
International immunopharmacology 2021 Dec;101(Pt B):108238
International immunopharmacology 2021 Dec;101(Pt B):108238
Senescence marker protein 30 inhibits tumor growth by reducing HDAC4 expression in non-small cell lung cancer.
Shao C, Guo K, Xu L, Zhang Y, Duan H, Feng Y, Pan M, Lu D, Ren X, Ganti AK, Hakozaki T, Han J, Yan X, Ma Z
Translational lung cancer research 2021 Dec;10(12):4558-4573
Translational lung cancer research 2021 Dec;10(12):4558-4573
Intron retention as a new pre-symptomatic marker of aging and its recovery to the normal state by a traditional Japanese multi-herbal medicine.
Okada N, Oshima K, Iwasaki Y, Maruko A, Matsumura K, Iioka E, Vu TD, Fujitsuka N, Nishi A, Sugiyama A, Nishiyama M, Kaneko A, Mizoguchi K, Yamamoto M, Nishimura S
Gene 2021 Aug 20;794:145752
Gene 2021 Aug 20;794:145752
Exogenous regucalcin negatively regulates the progression of cervical adenocarcinoma.
Li X, Huang Y, Guo S, Xie M, Bin X, Shi M, Chen A, Chen S, Wu F, Hu Q, Zhou S
Oncology letters 2019 Jul;18(1):609-616
Oncology letters 2019 Jul;18(1):609-616
A mechanism of regucalcin knock-down in the promotion of proliferation and movement of human cervical cancer HeLa cells.
Li X, Huang Y, Wang P, Song W, Yao Q, Hu Q, Zhou S
Translational cancer research 2019 Apr;8(2):402-409
Translational cancer research 2019 Apr;8(2):402-409
Hepatic thyroid signaling of heat-stressed late pregnant and early lactating cows.
Weitzel JM, Viergutz T, Albrecht D, Bruckmaier R, Schmicke M, Tuchscherer A, Koch F, Kuhla B
The Journal of endocrinology 2017 Aug;234(2):129-141
The Journal of endocrinology 2017 Aug;234(2):129-141
Dioscin, a natural steroid saponin, shows remarkable protective effect against acetaminophen-induced liver damage in vitro and in vivo.
Zhao X, Cong X, Zheng L, Xu L, Yin L, Peng J
Toxicology letters 2012 Oct 2;214(1):69-80
Toxicology letters 2012 Oct 2;214(1):69-80
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse liver tissue were subjected to SDS PAGE followed by western blot with 17947-1-AP(RGN,SMP30 antibody) at dilution of 1:1000
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- rat liver tissue were subjected to SDS PAGE followed by western blot with 17947-1-AP( RGN,SMP30 Antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The RGN/SMP30 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human RGN/SMP30. This antibody recognizes human,mouse,rat antigen. The RGN/SMP30 antibody has been validated for the following applications: ELISA, WB, IHC analysis.