Tissue expression
Cell line expression
Protein structure
UBE2R2
Ubiquitin conjugating enzyme E2 R2CDC34B, FLJ20419, MGC10481, UBC3B
Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| antibodies-online | 5 references | Monoclonal |
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| LSBio | Polyclonal |
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| Proteintech Group | 4 references | Polyclonal |
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| Invitrogen Antibodies | Polyclonal |
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| Novus Biologicals | Monoclonal |
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