Tissue expression
Cell line expression
Protein structure

LARGE1

LARGE xylosyl- and glucuronyltransferase 1
KIAA0609, LARGE 
This gene encodes a member of the N-acetylglucosaminyltransferase gene family. It encodes a glycosyltransferase which participates in glycosylation of alpha-dystroglycan, and may carry out the synthesis of glycoprotein and glycosphingolipid sugar chains. It may also be involved in the addition of a repeated disaccharide unit. The protein encoded by this gene is the glycotransferase that adds the final xylose and glucuronic acid to alpha-dystroglycan and thereby allows alpha-dystroglycan to bind ligands including laminin 211 and neurexin. Mutations in this gene cause several forms of congenital muscular dystrophy characterized by cognitive disability and abnormal glycosylation of alpha-dystroglycan. Alternative splicing of this gene results in multiple transcript variants that encode the same protein. [provided by RefSeq, May 2018]
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175 antibodies from 29 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
28 antibodies
antibodies-online
35 antibodies
Invitrogen Antibodies
6 antibodies
GeneTex
3 antibodies
OriGene
4 antibodies
Everest Biotech
2 antibodies
St John's Laboratory
2 antibodies
Proteintech Group
1 antibody
Biorbyt
11 antibodies
Antibodies.com
3 antibodies
Abiocode, Inc.
1 antibody
Boster Biological Technology
1 antibody
NovoPro Bioscience Inc.
1 antibody
Wuhan Fine Biotech Co., Ltd.
1 antibody
Acris Antibodies GmbH
3 antibodies
NSJ Bioreagents
2 antibodies
Aviva Systems Biology
3 antibodies
Abnova Corporation
4 antibodies
Abgent
2 antibodies
Arigo
1 antibody
ProSci
3 antibodies
MilliporeSigma / Merck KGaA
2 antibodies
Creative Diagnostics
3 antibodies
MyBioSource
2 antibodies
United States Biological
24 antibodies
Leading Biology
2 antibodies
Abbexa
3 antibodies
Creative Biolabs
1 antibody