Antibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
Reference
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- Product number
- 12434-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12434-1-AP, RRID:AB_2199965
- Product name
- STAM antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated STAM antibody (Cat. #12434-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references A combined EM and proteomic analysis places HIV-1 Vpu at the crossroads of retromer and ESCRT complexes: PTPN23 is a Vpu-cofactor.
Endofin is required for HD-PTP and ESCRT-0 interdependent endosomal sorting of ubiquitinated transmembrane cargoes.
Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.
Endosomal membrane tension regulates ESCRT-III-dependent intra-lumenal vesicle formation.
TIM-1 Ubiquitination Mediates Dengue Virus Entry.
The α-Arrestin ARRDC3 Regulates the Endosomal Residence Time and Intracellular Signaling of the β2-Adrenergic Receptor.
Identification of STAM1 as a novel effector of ventral projection of spinal motor neurons.
β-Arrestin1 and Signal-transducing Adaptor Molecule 1 (STAM1) Cooperate to Promote Focal Adhesion Kinase Autophosphorylation and Chemotaxis via the Chemokine Receptor CXCR4.
The endosomal sorting complex required for transport pathway mediates chemokine receptor CXCR4-promoted lysosomal degradation of the mammalian target of rapamycin antagonist DEPTOR.
The ubiquitin ligase deltex-3l regulates endosomal sorting of the G protein-coupled receptor CXCR4.
Novel roles for the E3 ubiquitin ligase atrophin-interacting protein 4 and signal transduction adaptor molecule 1 in G protein-coupled receptor signaling.
Arrestin-2 interacts with the endosomal sorting complex required for transport machinery to modulate endosomal sorting of CXCR4.
Stoneham CA, Langer S, De Jesus PD, Wozniak JM, Lapek J, Deerinck T, Thor A, Pache L, Chanda SK, Gonzalez DJ, Ellisman M, Guatelli J
PLoS pathogens 2021 Nov;17(11):e1009409
PLoS pathogens 2021 Nov;17(11):e1009409
Endofin is required for HD-PTP and ESCRT-0 interdependent endosomal sorting of ubiquitinated transmembrane cargoes.
Kazan JM, Desrochers G, Martin CE, Jeong H, Kharitidi D, Apaja PM, Roldan A, St Denis N, Gingras AC, Lukacs GL, Pause A
iScience 2021 Nov 19;24(11):103274
iScience 2021 Nov 19;24(11):103274
Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.
Zellner S, Schifferer M, Behrends C
Molecular cell 2021 Mar 18;81(6):1337-1354.e8
Molecular cell 2021 Mar 18;81(6):1337-1354.e8
Endosomal membrane tension regulates ESCRT-III-dependent intra-lumenal vesicle formation.
Mercier V, Larios J, Molinard G, Goujon A, Matile S, Gruenberg J, Roux A
Nature cell biology 2020 Aug;22(8):947-959
Nature cell biology 2020 Aug;22(8):947-959
TIM-1 Ubiquitination Mediates Dengue Virus Entry.
Dejarnac O, Hafirassou ML, Chazal M, Versapuech M, Gaillard J, Perera-Lecoin M, Umana-Diaz C, Bonnet-Madin L, Carnec X, Tinevez JY, Delaugerre C, Schwartz O, Roingeard P, Jouvenet N, Berlioz-Torrent C, Meertens L, Amara A
Cell reports 2018 May 8;23(6):1779-1793
Cell reports 2018 May 8;23(6):1779-1793
The α-Arrestin ARRDC3 Regulates the Endosomal Residence Time and Intracellular Signaling of the β2-Adrenergic Receptor.
Tian X, Irannejad R, Bowman SL, Du Y, Puthenveedu MA, von Zastrow M, Benovic JL
The Journal of biological chemistry 2016 Jul 8;291(28):14510-25
The Journal of biological chemistry 2016 Jul 8;291(28):14510-25
Identification of STAM1 as a novel effector of ventral projection of spinal motor neurons.
Nam H, Lee S
Development (Cambridge, England) 2016 Jul 1;143(13):2334-43
Development (Cambridge, England) 2016 Jul 1;143(13):2334-43
β-Arrestin1 and Signal-transducing Adaptor Molecule 1 (STAM1) Cooperate to Promote Focal Adhesion Kinase Autophosphorylation and Chemotaxis via the Chemokine Receptor CXCR4.
Alekhina O, Marchese A
The Journal of biological chemistry 2016 Dec 9;291(50):26083-26097
The Journal of biological chemistry 2016 Dec 9;291(50):26083-26097
The endosomal sorting complex required for transport pathway mediates chemokine receptor CXCR4-promoted lysosomal degradation of the mammalian target of rapamycin antagonist DEPTOR.
Verma R, Marchese A
The Journal of biological chemistry 2015 Mar 13;290(11):6810-24
The Journal of biological chemistry 2015 Mar 13;290(11):6810-24
The ubiquitin ligase deltex-3l regulates endosomal sorting of the G protein-coupled receptor CXCR4.
Holleman J, Marchese A
Molecular biology of the cell 2014 Jun 15;25(12):1892-904
Molecular biology of the cell 2014 Jun 15;25(12):1892-904
Novel roles for the E3 ubiquitin ligase atrophin-interacting protein 4 and signal transduction adaptor molecule 1 in G protein-coupled receptor signaling.
Malik R, Soh UJ, Trejo J, Marchese A
The Journal of biological chemistry 2012 Mar 16;287(12):9013-27
The Journal of biological chemistry 2012 Mar 16;287(12):9013-27
Arrestin-2 interacts with the endosomal sorting complex required for transport machinery to modulate endosomal sorting of CXCR4.
Malik R, Marchese A
Molecular biology of the cell 2010 Jul 15;21(14):2529-41
Molecular biology of the cell 2010 Jul 15;21(14):2529-41
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- PC-3 cells were subjected to SDS PAGE followed by western blot with 12434-1-AP(STAM antibody) at dilution of 1:300
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using STAM antibody 12434-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line