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- Product number
- 12434-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12434-1-AP, RRID:AB_2199965
- Product name
- STAM antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated STAM antibody (Cat. #12434-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Mapping of endosomal proximity proteomes reveals Retromer as a hub for RAB GTPase regulation.
A MYC-STAMBPL1-TOE1 positive feedback loop mediates EGFR stability in hepatocellular carcinoma.
A ubiquitin-specific, proximity-based labeling approach for the identification of ubiquitin ligase substrates.
Upregulation of the ESCRT pathway and multivesicular bodies accelerates degradation of proteins associated with neurodegeneration.
Proximity Labeling to Identify β-Arrestin1 Binding Partners Downstream of Ligand-Activated G Protein-Coupled Receptors.
β-arrestin1 is an E3 ubiquitin ligase adaptor for substrate linear polyubiquitination.
A phosphoinositide signalling pathway mediates rapid lysosomal repair.
Neuroprogenitor Cells From Patients With TBCK Encephalopathy Suggest Deregulation of Early Secretory Vesicle Transport.
A combined EM and proteomic analysis places HIV-1 Vpu at the crossroads of retromer and ESCRT complexes: PTPN23 is a Vpu-cofactor.
Endofin is required for HD-PTP and ESCRT-0 interdependent endosomal sorting of ubiquitinated transmembrane cargoes.
Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.
A non-GPCR-binding partner interacts with a novel surface on β-arrestin1 to mediate GPCR signaling.
ALIX- and ESCRT-III-dependent sorting of tetraspanins to exosomes.
Endosomal membrane tension regulates ESCRT-III-dependent intra-lumenal vesicle formation.
TIM-1 Ubiquitination Mediates Dengue Virus Entry.
The α-Arrestin ARRDC3 Regulates the Endosomal Residence Time and Intracellular Signaling of the β2-Adrenergic Receptor.
Identification of STAM1 as a novel effector of ventral projection of spinal motor neurons.
β-Arrestin1 and Signal-transducing Adaptor Molecule 1 (STAM1) Cooperate to Promote Focal Adhesion Kinase Autophosphorylation and Chemotaxis via the Chemokine Receptor CXCR4.
The endosomal sorting complex required for transport pathway mediates chemokine receptor CXCR4-promoted lysosomal degradation of the mammalian target of rapamycin antagonist DEPTOR.
The ubiquitin ligase deltex-3l regulates endosomal sorting of the G protein-coupled receptor CXCR4.
Novel roles for the E3 ubiquitin ligase atrophin-interacting protein 4 and signal transduction adaptor molecule 1 in G protein-coupled receptor signaling.
Arrestin-2 interacts with the endosomal sorting complex required for transport machinery to modulate endosomal sorting of CXCR4.
Antón-Plágaro C, Chen KE, Guo Q, Liu M, Evans AJ, Lewis PA, Heesom KJ, Wilkinson KA, Collins BM, Cullen PJ
Nature communications 2025 Jul 30;16(1):6990
Nature communications 2025 Jul 30;16(1):6990
A MYC-STAMBPL1-TOE1 positive feedback loop mediates EGFR stability in hepatocellular carcinoma.
Zhang H, Wang Z, Zhang J, Li Z, Liu J, Yu J, Zhao Y, Guo F, Chen WD, Wang YD
Cell reports 2024 Oct 22;43(10):114812
Cell reports 2024 Oct 22;43(10):114812
A ubiquitin-specific, proximity-based labeling approach for the identification of ubiquitin ligase substrates.
Mukhopadhyay U, Levantovsky S, Carusone TM, Gharbi S, Stein F, Behrends C, Bhogaraju S
Science advances 2024 Aug 9;10(32):eadp3000
Science advances 2024 Aug 9;10(32):eadp3000
Upregulation of the ESCRT pathway and multivesicular bodies accelerates degradation of proteins associated with neurodegeneration.
Benyair R, Giridharan SSP, Rivero-Ríos P, Hasegawa J, Bristow E, Eskelinen EL, Shmueli MD, Fishbain-Yoskovitz V, Merbl Y, Sharkey LM, Paulson HL, Hanson PI, Patnaik S, Al-Ramahi I, Botas J, Marugan J, Weisman LS
Autophagy reports 2023;2(1)
Autophagy reports 2023;2(1)
Proximity Labeling to Identify β-Arrestin1 Binding Partners Downstream of Ligand-Activated G Protein-Coupled Receptors.
Zhuo Y, Robleto VL, Marchese A
International journal of molecular sciences 2023 Feb 7;24(4)
International journal of molecular sciences 2023 Feb 7;24(4)
β-arrestin1 is an E3 ubiquitin ligase adaptor for substrate linear polyubiquitination.
McElrath CJ, Benzow S, Zhuo Y, Marchese A
The Journal of biological chemistry 2023 Dec;299(12):105474
The Journal of biological chemistry 2023 Dec;299(12):105474
A phosphoinositide signalling pathway mediates rapid lysosomal repair.
Tan JX, Finkel T
Nature 2022 Sep;609(7928):815-821
Nature 2022 Sep;609(7928):815-821
Neuroprogenitor Cells From Patients With TBCK Encephalopathy Suggest Deregulation of Early Secretory Vesicle Transport.
Moreira DP, Suzuki AM, Silva ALTE, Varella-Branco E, Meneghetti MCZ, Kobayashi GS, Fogo M, Ferrari MFR, Cardoso RR, Lourenço NCV, Griesi-Oliveira K, Zachi EC, Bertola DR, Weinmann KS, de Lima MA, Nader HB, Sertié AL, Passos-Bueno MR
Frontiers in cellular neuroscience 2021;15:803302
Frontiers in cellular neuroscience 2021;15:803302
A combined EM and proteomic analysis places HIV-1 Vpu at the crossroads of retromer and ESCRT complexes: PTPN23 is a Vpu-cofactor.
Stoneham CA, Langer S, De Jesus PD, Wozniak JM, Lapek J, Deerinck T, Thor A, Pache L, Chanda SK, Gonzalez DJ, Ellisman M, Guatelli J
PLoS pathogens 2021 Nov;17(11):e1009409
PLoS pathogens 2021 Nov;17(11):e1009409
Endofin is required for HD-PTP and ESCRT-0 interdependent endosomal sorting of ubiquitinated transmembrane cargoes.
Kazan JM, Desrochers G, Martin CE, Jeong H, Kharitidi D, Apaja PM, Roldan A, St Denis N, Gingras AC, Lukacs GL, Pause A
iScience 2021 Nov 19;24(11):103274
iScience 2021 Nov 19;24(11):103274
Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.
Zellner S, Schifferer M, Behrends C
Molecular cell 2021 Mar 18;81(6):1337-1354.e8
Molecular cell 2021 Mar 18;81(6):1337-1354.e8
A non-GPCR-binding partner interacts with a novel surface on β-arrestin1 to mediate GPCR signaling.
Zhuo Y, Gurevich VV, Vishnivetskiy SA, Klug CS, Marchese A
The Journal of biological chemistry 2020 Oct 9;295(41):14111-14124
The Journal of biological chemistry 2020 Oct 9;295(41):14111-14124
ALIX- and ESCRT-III-dependent sorting of tetraspanins to exosomes.
Larios J, Mercier V, Roux A, Gruenberg J
The Journal of cell biology 2020 Mar 2;219(3)
The Journal of cell biology 2020 Mar 2;219(3)
Endosomal membrane tension regulates ESCRT-III-dependent intra-lumenal vesicle formation.
Mercier V, Larios J, Molinard G, Goujon A, Matile S, Gruenberg J, Roux A
Nature cell biology 2020 Aug;22(8):947-959
Nature cell biology 2020 Aug;22(8):947-959
TIM-1 Ubiquitination Mediates Dengue Virus Entry.
Dejarnac O, Hafirassou ML, Chazal M, Versapuech M, Gaillard J, Perera-Lecoin M, Umana-Diaz C, Bonnet-Madin L, Carnec X, Tinevez JY, Delaugerre C, Schwartz O, Roingeard P, Jouvenet N, Berlioz-Torrent C, Meertens L, Amara A
Cell reports 2018 May 8;23(6):1779-1793
Cell reports 2018 May 8;23(6):1779-1793
The α-Arrestin ARRDC3 Regulates the Endosomal Residence Time and Intracellular Signaling of the β2-Adrenergic Receptor.
Tian X, Irannejad R, Bowman SL, Du Y, Puthenveedu MA, von Zastrow M, Benovic JL
The Journal of biological chemistry 2016 Jul 8;291(28):14510-25
The Journal of biological chemistry 2016 Jul 8;291(28):14510-25
Identification of STAM1 as a novel effector of ventral projection of spinal motor neurons.
Nam H, Lee S
Development (Cambridge, England) 2016 Jul 1;143(13):2334-43
Development (Cambridge, England) 2016 Jul 1;143(13):2334-43
β-Arrestin1 and Signal-transducing Adaptor Molecule 1 (STAM1) Cooperate to Promote Focal Adhesion Kinase Autophosphorylation and Chemotaxis via the Chemokine Receptor CXCR4.
Alekhina O, Marchese A
The Journal of biological chemistry 2016 Dec 9;291(50):26083-26097
The Journal of biological chemistry 2016 Dec 9;291(50):26083-26097
The endosomal sorting complex required for transport pathway mediates chemokine receptor CXCR4-promoted lysosomal degradation of the mammalian target of rapamycin antagonist DEPTOR.
Verma R, Marchese A
The Journal of biological chemistry 2015 Mar 13;290(11):6810-24
The Journal of biological chemistry 2015 Mar 13;290(11):6810-24
The ubiquitin ligase deltex-3l regulates endosomal sorting of the G protein-coupled receptor CXCR4.
Holleman J, Marchese A
Molecular biology of the cell 2014 Jun 15;25(12):1892-904
Molecular biology of the cell 2014 Jun 15;25(12):1892-904
Novel roles for the E3 ubiquitin ligase atrophin-interacting protein 4 and signal transduction adaptor molecule 1 in G protein-coupled receptor signaling.
Malik R, Soh UJ, Trejo J, Marchese A
The Journal of biological chemistry 2012 Mar 16;287(12):9013-27
The Journal of biological chemistry 2012 Mar 16;287(12):9013-27
Arrestin-2 interacts with the endosomal sorting complex required for transport machinery to modulate endosomal sorting of CXCR4.
Malik R, Marchese A
Molecular biology of the cell 2010 Jul 15;21(14):2529-41
Molecular biology of the cell 2010 Jul 15;21(14):2529-41
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- PC-3 cells were subjected to SDS PAGE followed by western blot with 12434-1-AP(STAM antibody) at dilution of 1:300
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using STAM antibody 12434-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
