Antibody data
- Antibody Data
- Antigen structure
- References [17]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 12717-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12717-1-AP, RRID:AB_2166978
- Product name
- PMP2 antibody
- Antibody type
- Polyclonal
- Description
- PMP2 antibody (Cat. #12717-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat, pig and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat, Porcine
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references PMP2 regulates myelin thickening and ATP production during remyelination.
Fatty acid-binding proteins 3, 7, and 8 bind cholesterol and facilitate its egress from lysosomes.
Formation of Müller glia-derived progenitor cells in retinas depleted of microglia.
Isolation of ferret astrocytes reveals their morphological, transcriptional, and functional differences from mouse astrocytes.
Conservation and divergence of myelin proteome and oligodendrocyte transcriptome profiles between humans and mice.
Disentangling glial diversity in peripheral nerves at single-nuclei resolution.
Piezo channels contribute to the regulation of myelination in Schwann cells.
Fatty acid metabolism is involved in both retinal physiology and the pathology of retinal vascular diseases.
ITPR3 facilitates tumor growth, metastasis and stemness by inducing the NF-ĸB/CD44 pathway in urinary bladder carcinoma.
Proteome profile of peripheral myelin in healthy mice and in a neuropathy model.
Macrophages Expressing GALC Improve Peripheral Krabbe Disease by a Mechanism Independent of Cross-Correction.
Neuregulin 1 type III improves peripheral nerve myelination in a mouse model of congenital hypomyelinating neuropathy.
Variation among intact tissue samples reveals the core transcriptional features of human CNS cell classes.
The Role of Peripheral Myelin Protein 2 in Remyelination.
Characterization of host response to Cryptococcus neoformans through quantitative proteomic analysis of cryptococcal meningitis co-infected with HIV.
A role of peripheral myelin protein 2 in lipid homeostasis of myelinating Schwann cells.
Identification of a novel set of genes reflecting different in vivo invasive patterns of human GBM cells.
Hong J, Garfolo R, Kabre S, Humml C, Velanac V, Roué C, Beck B, Jeanette H, Haslam S, Bach M, Arora S, Acheta J, Nave KA, Schwab MH, Jourd'heuil D, Poitelon Y, Belin S
Glia 2024 May;72(5):885-898
Glia 2024 May;72(5):885-898
Fatty acid-binding proteins 3, 7, and 8 bind cholesterol and facilitate its egress from lysosomes.
Fang XX, Wei P, Zhao K, Sheng ZC, Song BL, Yin L, Luo J
The Journal of cell biology 2024 Apr 1;223(4)
The Journal of cell biology 2024 Apr 1;223(4)
Formation of Müller glia-derived progenitor cells in retinas depleted of microglia.
El-Hodiri HM, Bentley J, Reske A, Palazzo I, Campbell WA, Halloy NR, Fischer AJ
bioRxiv : the preprint server for biology 2023 Jun 9;
bioRxiv : the preprint server for biology 2023 Jun 9;
Isolation of ferret astrocytes reveals their morphological, transcriptional, and functional differences from mouse astrocytes.
Roboon J, Hattori T, Nguyen DT, Ishii H, Takarada-Iemata M, Kannon T, Hosomichi K, Maejima T, Saito K, Shinmyo Y, Mieda M, Tajima A, Kawasaki H, Hori O
Frontiers in cellular neuroscience 2022;16:877131
Frontiers in cellular neuroscience 2022;16:877131
Conservation and divergence of myelin proteome and oligodendrocyte transcriptome profiles between humans and mice.
Gargareta VI, Reuschenbach J, Siems SB, Sun T, Piepkorn L, Mangana C, Späte E, Goebbels S, Huitinga I, Möbius W, Nave KA, Jahn O, Werner HB
eLife 2022 May 11;11
eLife 2022 May 11;11
Disentangling glial diversity in peripheral nerves at single-nuclei resolution.
Yim AKY, Wang PL, Bermingham JR Jr, Hackett A, Strickland A, Miller TM, Ly C, Mitra RD, Milbrandt J
Nature neuroscience 2022 Feb;25(2):238-251
Nature neuroscience 2022 Feb;25(2):238-251
Piezo channels contribute to the regulation of myelination in Schwann cells.
Acheta J, Bhatia U, Haley J, Hong J, Rich K, Close R, Bechler ME, Belin S, Poitelon Y
Glia 2022 Dec;70(12):2276-2289
Glia 2022 Dec;70(12):2276-2289
Fatty acid metabolism is involved in both retinal physiology and the pathology of retinal vascular diseases.
Umetsu A, Furuhashi M, Watanabe M, Ohkawa E, Tsugeno Y, Suzuki S, Itoh K, Ida Y, Hikage F, Ohguro H
Prostaglandins, leukotrienes, and essential fatty acids 2022 Aug;183:102473
Prostaglandins, leukotrienes, and essential fatty acids 2022 Aug;183:102473
ITPR3 facilitates tumor growth, metastasis and stemness by inducing the NF-ĸB/CD44 pathway in urinary bladder carcinoma.
Zhang M, Wang L, Yue Y, Zhang L, Liu T, Jing M, Liang X, Ma M, Xu S, Wang K, Wang X, Fan J
Journal of experimental & clinical cancer research : CR 2021 Feb 11;40(1):65
Journal of experimental & clinical cancer research : CR 2021 Feb 11;40(1):65
Proteome profile of peripheral myelin in healthy mice and in a neuropathy model.
Siems SB, Jahn O, Eichel MA, Kannaiyan N, Wu LMN, Sherman DL, Kusch K, Hesse D, Jung RB, Fledrich R, Sereda MW, Rossner MJ, Brophy PJ, Werner HB
eLife 2020 Mar 4;9
eLife 2020 Mar 4;9
Macrophages Expressing GALC Improve Peripheral Krabbe Disease by a Mechanism Independent of Cross-Correction.
Weinstock NI, Shin D, Dhimal N, Hong X, Irons EE, Silvestri NJ, Reed CB, Nguyen D, Sampson O, Cheng YC, Lau JTY, Bongarzone ER, Kofler J, Escolar ML, Gelb MH, Wrabetz L, Feltri ML
Neuron 2020 Jul 8;107(1):65-81.e9
Neuron 2020 Jul 8;107(1):65-81.e9
Neuregulin 1 type III improves peripheral nerve myelination in a mouse model of congenital hypomyelinating neuropathy.
Belin S, Ornaghi F, Shackleford G, Wang J, Scapin C, Lopez-Anido C, Silvestri N, Robertson N, Williamson C, Ishii A, Taveggia C, Svaren J, Bansal R, Schwab MH, Nave K, Fratta P, D'Antonio M, Poitelon Y, Feltri ML, Wrabetz L
Human molecular genetics 2019 Apr 15;28(8):1260-1273
Human molecular genetics 2019 Apr 15;28(8):1260-1273
Variation among intact tissue samples reveals the core transcriptional features of human CNS cell classes.
Kelley KW, Nakao-Inoue H, Molofsky AV, Oldham MC
Nature neuroscience 2018 Sep;21(9):1171-1184
Nature neuroscience 2018 Sep;21(9):1171-1184
The Role of Peripheral Myelin Protein 2 in Remyelination.
Stettner M, Zenker J, Klingler F, Szepanowski F, Hartung HP, Mausberg AK, Kleinschnitz C, Chrast R, Kieseier BC
Cellular and molecular neurobiology 2018 Mar;38(2):487-496
Cellular and molecular neurobiology 2018 Mar;38(2):487-496
Characterization of host response to Cryptococcus neoformans through quantitative proteomic analysis of cryptococcal meningitis co-infected with HIV.
Selvan LD, Sreenivasamurthy SK, Kumar S, Yelamanchi SD, Madugundu AK, Anil AK, Renuse S, Nair BG, Gowda H, Mathur PP, Satishchandra P, Shankar SK, Mahadevan A, Keshava Prasad TS
Molecular bioSystems 2015 Sep;11(9):2529-40
Molecular bioSystems 2015 Sep;11(9):2529-40
A role of peripheral myelin protein 2 in lipid homeostasis of myelinating Schwann cells.
Zenker J, Stettner M, Ruskamo S, Domènech-Estévez E, Baloui H, Médard JJ, Verheijen MH, Brouwers JF, Kursula P, Kieseier BC, Chrast R
Glia 2014 Sep;62(9):1502-12
Glia 2014 Sep;62(9):1502-12
Identification of a novel set of genes reflecting different in vivo invasive patterns of human GBM cells.
Monticone M, Daga A, Candiani S, Romeo F, Mirisola V, Viaggi S, Melloni I, Pedemonte S, Zona G, Giaretti W, Pfeffer U, Castagnola P
BMC cancer 2012 Aug 17;12:358
BMC cancer 2012 Aug 17;12:358
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse testis tissue were subjected to SDS PAGE followed by western blot with 12717-1-AP(PMP2 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PMP2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PMP2. This antibody recognizes human, mouse, rat antigen. The PMP2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.