Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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Validation data
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- Product number
- HPA049977 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA049977, RRID:AB_2680978
- Product name
- Anti-GMNN
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human GMNN, Gene description: geminin, DNA replication inhibitor, Alternative Gene Names: Gem, Validated applications: ICC, IHC, Uniprot ID: O75496, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.4 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references CDT1 inhibits CMG helicase in early S phase to separate origin licensing from DNA synthesis.
Altered G1 signaling order and commitment point in cells proliferating without CDK4/6 activity
EMI1 switches from being a substrate to an inhibitor of APC/CCDH1 to start the cell cycle
Irreversible APC Cdh1 Inactivation Underlies the Point of No Return for Cell-Cycle Entry
Ratnayeke N, Baris Y, Chung M, Yeeles JTP, Meyer T
Molecular cell 2023 Jan 5;83(1):26-42.e13
Molecular cell 2023 Jan 5;83(1):26-42.e13
Altered G1 signaling order and commitment point in cells proliferating without CDK4/6 activity
Liu C, Konagaya Y, Chung M, Daigh L, Fan Y, Yang H, Terai K, Matsuda M, Meyer T
Nature Communications 2020;11(1)
Nature Communications 2020;11(1)
EMI1 switches from being a substrate to an inhibitor of APC/CCDH1 to start the cell cycle
Cappell S, Mark K, Garbett D, Pack L, Rape M, Meyer T
Nature 2018;558(7709):313-317
Nature 2018;558(7709):313-317
Irreversible APC Cdh1 Inactivation Underlies the Point of No Return for Cell-Cycle Entry
Cappell S, Chung M, Jaimovich A, Spencer S, Meyer T
Cell 2016;166(1):167-180
Cell 2016;166(1):167-180
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human testis and skeletal muscle tissues using Anti-GMNN antibody. Corresponding GMNN RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol