Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 22340-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- USP11 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated USP11 antibody (Cat. #22340-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references USP11 promotes glycolysis by regulating HIF-1α stability in hepatocellular carcinoma.
USP11-mediated LSH deubiquitination inhibits ferroptosis in colorectal cancer through epigenetic activation of CYP24A1.
X-linked ubiquitin-specific peptidase 11 increases tauopathy vulnerability in women.
Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia.
Knockdown of RRM1 in tumor cells promotes radio-/chemotherapy induced ferroptosis by regulating p53 ubiquitination and p21-GPX4 signaling axis.
TRIM32/USP11 Balances ARID1A Stability and the Oncogenic/Tumor-Suppressive Status of Squamous Cell Carcinoma.
Ubiquitin-specific protease 11 serves as a marker of poor prognosis and promotes metastasis in hepatocellular carcinoma.
Qiao L, Hu W, Li L, Chen X, Liu L, Wang J
Journal of cellular and molecular medicine 2024 Jan;28(2):e18017
Journal of cellular and molecular medicine 2024 Jan;28(2):e18017
USP11-mediated LSH deubiquitination inhibits ferroptosis in colorectal cancer through epigenetic activation of CYP24A1.
Duan J, Huang D, Liu C, Lv Y, Zhang L, Chang F, Zeng X, Li L, Wang W, Shao G
Cell death & disease 2023 Jul 6;14(7):402
Cell death & disease 2023 Jul 6;14(7):402
X-linked ubiquitin-specific peptidase 11 increases tauopathy vulnerability in women.
Yan Y, Wang X, Chaput D, Shin MK, Koh Y, Gan L, Pieper AA, Woo JA, Kang DE
Cell 2022 Oct 13;185(21):3913-3930.e19
Cell 2022 Oct 13;185(21):3913-3930.e19
Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia.
Jin Q, Gutierrez Diaz B, Pieters T, Zhou Y, Narang S, Fijalkwoski I, Borin C, Van Laere J, Payton M, Cho BK, Han C, Sun L, Serafin V, Yacu G, Von Loocke W, Basso G, Veltri G, Dreveny I, Ben-Sahra I, Goo YA, Safgren SL, Tsai YC, Bornhauser B, Suraneni PK, Gaspar-Maia A, Kandela I, Van Vlierberghe P, Crispino JD, Tsirigos A, Ntziachristos P
Science advances 2022 Dec 9;8(49):eabq8437
Science advances 2022 Dec 9;8(49):eabq8437
Knockdown of RRM1 in tumor cells promotes radio-/chemotherapy induced ferroptosis by regulating p53 ubiquitination and p21-GPX4 signaling axis.
Gao Y, Chen B, Wang R, Xu A, Wu L, Lu H, Zhao G
Cell death discovery 2022 Aug 1;8(1):343
Cell death discovery 2022 Aug 1;8(1):343
TRIM32/USP11 Balances ARID1A Stability and the Oncogenic/Tumor-Suppressive Status of Squamous Cell Carcinoma.
Luo Q, Wu X, Nan Y, Chang W, Zhao P, Zhang Y, Su D, Liu Z
Cell reports 2020 Jan 7;30(1):98-111.e5
Cell reports 2020 Jan 7;30(1):98-111.e5
Ubiquitin-specific protease 11 serves as a marker of poor prognosis and promotes metastasis in hepatocellular carcinoma.
Zhang S, Xie C, Li H, Zhang K, Li J, Wang X, Yin Z
Laboratory investigation; a journal of technical methods and pathology 2018 Jul;98(7):883-894
Laboratory investigation; a journal of technical methods and pathology 2018 Jul;98(7):883-894
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- A549 cells were subjected to SDS PAGE followed by western blot with 22340-1-AP(USP11 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The USP11 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human USP11. This antibody recognizes human antigen. The USP11 antibody has been validated for the following applications: ELISA, WB, IHC analysis.