Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 10244-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10244-1-AP, RRID:AB_2288400
- Product name
- USP11 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated USP11 antibody (Cat. #10244-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references USP11 Exacerbates Radiation-Induced Pneumonitis by Activating Endothelial Cell Inflammatory Response via OTUD5-STING Signaling.
The deubiquitinase USP11 regulates cell proliferation and ferroptotic cell death via stabilization of NRF2 USP11 deubiquitinates and stabilizes NRF2.
XRCC1 protects transcription from toxic PARP1 activity during DNA base excision repair.
The E2F1/USP11 positive feedback loop promotes hepatocellular carcinoma metastasis and inhibits autophagy by activating ERK/mTOR pathway.
Aberrant USP11 expression regulates NF90 to promote proliferation and metastasis in hepatocellular carcinoma.
A feedforward circuit shaped by ECT2 and USP7 contributes to breast carcinogenesis.
EGFR-vIII downregulated H2AZK4/7AC though the PI3K/AKT-HDAC2 axis to regulate cell cycle progression.
CRL4(DCAF8) and USP11 oppositely regulate the stability of myeloid leukemia factors (MLFs).
Ubiquitin-specific protease 11 (USP11) functions as a tumor suppressor through deubiquitinating and stabilizing VGLL4 protein.
Ubiquitin-specific protease 11 functions as a tumor suppressor by modulating Mgl-1 protein to regulate cancer cell growth.
Tang Y, Wang T, Gu L, Xu Y, Yang Z, Zhu W, Zhang Q, Luo J, Cao J, Jiao Y
International journal of radiation oncology, biology, physics 2024 Jul 15;119(4):1261-1274
International journal of radiation oncology, biology, physics 2024 Jul 15;119(4):1261-1274
The deubiquitinase USP11 regulates cell proliferation and ferroptotic cell death via stabilization of NRF2 USP11 deubiquitinates and stabilizes NRF2.
Meng C, Zhan J, Chen D, Shao G, Zhang H, Gu W, Luo J
Oncogene 2021 Mar;40(9):1706-1720
Oncogene 2021 Mar;40(9):1706-1720
XRCC1 protects transcription from toxic PARP1 activity during DNA base excision repair.
Adamowicz M, Hailstone R, Demin AA, Komulainen E, Hanzlikova H, Brazina J, Gautam A, Wells SE, Caldecott KW
Nature cell biology 2021 Dec;23(12):1287-1298
Nature cell biology 2021 Dec;23(12):1287-1298
The E2F1/USP11 positive feedback loop promotes hepatocellular carcinoma metastasis and inhibits autophagy by activating ERK/mTOR pathway.
Qiao L, Zhang Q, Sun Z, Liu Q, Wu Z, Hu W, Bao S, Yang Q, Liu L
Cancer letters 2021 Aug 28;514:63-78
Cancer letters 2021 Aug 28;514:63-78
Aberrant USP11 expression regulates NF90 to promote proliferation and metastasis in hepatocellular carcinoma.
Zhang C, Xie C, Wang X, Huang Y, Gao S, Lu J, Lu Y, Zhang S
American journal of cancer research 2020;10(5):1416-1428
American journal of cancer research 2020;10(5):1416-1428
A feedforward circuit shaped by ECT2 and USP7 contributes to breast carcinogenesis.
Zhang Q, Cao C, Gong W, Bao K, Wang Q, Wang Y, Bi L, Ma S, Zhao J, Liu L, Tian S, Zhang K, Yang J, Yao Z, Song N, Shi L
Theranostics 2020;10(23):10769-10790
Theranostics 2020;10(23):10769-10790
EGFR-vIII downregulated H2AZK4/7AC though the PI3K/AKT-HDAC2 axis to regulate cell cycle progression.
Zhao H, Wang Y, Yang C, Zhou J, Wang L, Yi K, Li Y, Wang Q, Shi J, Kang C, Zeng L
Clinical and translational medicine 2020 Jan 28;9(1):10
Clinical and translational medicine 2020 Jan 28;9(1):10
CRL4(DCAF8) and USP11 oppositely regulate the stability of myeloid leukemia factors (MLFs).
Huang D, Liu C, Sun X, Sun X, Qu Y, Tang Y, Li G, Tong T
Biochemical and biophysical research communications 2020 Aug 20;529(2):127-132
Biochemical and biophysical research communications 2020 Aug 20;529(2):127-132
Ubiquitin-specific protease 11 (USP11) functions as a tumor suppressor through deubiquitinating and stabilizing VGLL4 protein.
Zhang E, Shen B, Mu X, Qin Y, Zhang F, Liu Y, Xiao J, Zhang P, Wang C, Tan M, Fan Y
American journal of cancer research 2016;6(12):2901-2909
American journal of cancer research 2016;6(12):2901-2909
Ubiquitin-specific protease 11 functions as a tumor suppressor by modulating Mgl-1 protein to regulate cancer cell growth.
Lim KH, Suresh B, Park JH, Kim YS, Ramakrishna S, Baek KH
Oncotarget 2016 Mar 22;7(12):14441-57
Oncotarget 2016 Mar 22;7(12):14441-57
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human testis tissue were subjected to SDS PAGE followed by western blot with 10244-1-AP(USP11 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The USP11 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human USP11. This antibody recognizes human antigen. The USP11 antibody has been validated for the following applications: ELISA, WB, IHC analysis.