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- References [13]
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- Product number
- 13517-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13517-1-AP, RRID:AB_10598475
- Product name
- SPARCL1 antibody
- Antibody type
- Polyclonal
- Description
- SPARCL1 antibody (Cat. #13517-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Sparcl1 mitigates abdominal aortic aneurysm through inhibiting lymphangiogenesis-mediated TLS formation.
Spatial transcriptomics of en bloc transurethral resection of bladder tumor specimens defines an invasive-front gene expression signature.
Dual tissue mRNA and serum protein signatures improve risk stratification in hepatocellular carcinoma.
SPARCL1 promotes chondrocytes extracellular matrix degradation and inflammation in osteoarthritis via TNF/NF-κB pathway.
Revolutionizing prognostic predictions in colorectal cancer: Macrophage‑driven transcriptional insights from single‑cell RNA sequencing and gene co‑expression network analysis.
FERMT2 upregulation in CAFs enhances EMT of OSCC and M2 macrophage polarization.
Downregulation of Sparc-like protein 1 during cisplatin-induced inhibition of myogenic differentiation of C2C12 myoblasts.
Endothelial genetic deletion of CD147 induces changes in the dual function of the blood-brain barrier and is implicated in Alzheimer's disease.
Secreted protein acidic and rich in cysteine (SPARC) knockout mice have greater outflow facility.
Olfactory ensheathing cells facilitate neurite sprouting and outgrowth by secreting high levels of hevin.
High secreted protein acidic and rich in cysteine expression in peritumoral fibroblasts predicts better prognosis in patients with resectable gastric cancer.
Integrated analysis reveals down-regulation of SPARCL1 is correlated with cervical cancer development and progression.
Defective synthesis and release of astrocytic thrombospondin-1 mediates the neuronal TDP-43 proteinopathy, resulting in defects in neuronal integrity associated with chronic traumatic encephalopathy: in vitro studies.
Chen MH, Hua YJ, Li Y, Lei Y, Zhou SY, Hu XD, Hu DH, Dong ZH, Lu Y, Zhuang T, Ruan CC
Nature immunology 2026 Apr;27(4):738-749
Nature immunology 2026 Apr;27(4):738-749
Spatial transcriptomics of en bloc transurethral resection of bladder tumor specimens defines an invasive-front gene expression signature.
Yoshihara K, Urabe F, Umemori M, Suzuki H, Ito K, Yanagisawa T, Sato S, Sekine K, Kimura T, Yamamoto Y
NPJ precision oncology 2026 Apr 14;
NPJ precision oncology 2026 Apr 14;
Dual tissue mRNA and serum protein signatures improve risk stratification in hepatocellular carcinoma.
Guo DF, Fan LW, Wen Q, Wang JK, Liang YH, Feng Q, Wang T, Zhang KH
NPJ precision oncology 2025 Nov 17;9(1):354
NPJ precision oncology 2025 Nov 17;9(1):354
SPARCL1 promotes chondrocytes extracellular matrix degradation and inflammation in osteoarthritis via TNF/NF-κB pathway.
Miao Y, Wu S, Gong Z, Chen Y, Xue F, Liu K, Zou J, Feng Y, Li G
Journal of orthopaedic translation 2024 May;46:116-128
Journal of orthopaedic translation 2024 May;46:116-128
Revolutionizing prognostic predictions in colorectal cancer: Macrophage‑driven transcriptional insights from single‑cell RNA sequencing and gene co‑expression network analysis.
Feng Y, Cheng Z, Gao J, Huang T, Wang J, Tang Q, Pu K, Liu C
Oncology letters 2024 Dec;28(6):587
Oncology letters 2024 Dec;28(6):587
FERMT2 upregulation in CAFs enhances EMT of OSCC and M2 macrophage polarization.
Ma X, Zhao D, Liu S, Zuo J, Wang W, Wang F, Li Y, Ding Z, Wang J, Wang X
Oral diseases 2024 Apr;30(3):991-1003
Oral diseases 2024 Apr;30(3):991-1003
Downregulation of Sparc-like protein 1 during cisplatin-induced inhibition of myogenic differentiation of C2C12 myoblasts.
Sakai H, Suzuki Y, Miyauchi Y, Sato F, Ando Y, Kon R, Ikarashi N, Chiba Y, Kamei J, Hosoe T
Biochemical pharmacology 2022 Oct;204:115234
Biochemical pharmacology 2022 Oct;204:115234
Endothelial genetic deletion of CD147 induces changes in the dual function of the blood-brain barrier and is implicated in Alzheimer's disease.
Wang H, Lv JJ, Zhao Y, Wei HL, Zhang TJ, Yang HJ, Chen ZN, Jiang JL
CNS neuroscience & therapeutics 2021 Sep;27(9):1048-1063
CNS neuroscience & therapeutics 2021 Sep;27(9):1048-1063
Secreted protein acidic and rich in cysteine (SPARC) knockout mice have greater outflow facility.
Yu L, Zheng Y, Liu BJ, Kang MH, Millar JC, Rhee DJ
PloS one 2020;15(11):e0241294
PloS one 2020;15(11):e0241294
Olfactory ensheathing cells facilitate neurite sprouting and outgrowth by secreting high levels of hevin.
Ge L, Zhuo Y, Wu P, Liu Y, Qi L, Teng X, Duan D, Chen P, Lu M
Journal of chemical neuroanatomy 2020 Mar;104:101728
Journal of chemical neuroanatomy 2020 Mar;104:101728
High secreted protein acidic and rich in cysteine expression in peritumoral fibroblasts predicts better prognosis in patients with resectable gastric cancer.
Nakajima M, Yoshino S, Kanekiyo S, Maeda N, Sakamoto K, Tsunedomi R, Suzuki N, Takeda S, Yamamoto S, Hazama S, Hoshii Y, Oga A, Itoh H, Ueno T, Nagano H
Oncology letters 2018 Jan;15(1):803-812
Oncology letters 2018 Jan;15(1):803-812
Integrated analysis reveals down-regulation of SPARCL1 is correlated with cervical cancer development and progression.
Wu DM, Shi J, Liu T, Deng SH, Han R, Xu Y
Cancer biomarkers : section A of Disease markers 2018 Feb 6;21(2):355-365
Cancer biomarkers : section A of Disease markers 2018 Feb 6;21(2):355-365
Defective synthesis and release of astrocytic thrombospondin-1 mediates the neuronal TDP-43 proteinopathy, resulting in defects in neuronal integrity associated with chronic traumatic encephalopathy: in vitro studies.
Jayakumar AR, Tong XY, Shamaladevi N, Barcelona S, Gaidosh G, Agarwal A, Norenberg MD
Journal of neurochemistry 2017 Feb;140(4):645-661
Journal of neurochemistry 2017 Feb;140(4):645-661
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SPARCL1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SPARCL1. This antibody recognizes human, mouse, rat antigen. The SPARCL1 antibody has been validated for the following applications: ELISA, WB analysis.
