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- References [19]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 12589-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12589-1-AP, RRID:AB_10638145
- Product name
- CDO1 antibody
- Antibody type
- Polyclonal
- Description
- CDO1 antibody (Cat. #12589-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat, pig and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat, Porcine
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references TRIM47-CDO1 axis dictates hepatocellular carcinoma progression by modulating ferroptotic cell death through the ubiquitin‒proteasome system.
Deletion of hepatocyte cysteine dioxygenase type 1, a bile acid repressed gene, enhances glutathione synthesis and ameliorates acetaminophen hepatotoxicity.
KLF10/CBS increases the sensitivity of gastric carcinoma cells to methionine restriction by promoting sulfur transfer pathway.
Comprehensive Metabolic Tracing Reveals the Origin and Catabolism of Cysteine in Mammalian Tissues and Tumors.
Taurine Alleviates Chronic Social Defeat Stress-Induced Depression by Protecting Cortical Neurons from Dendritic Spine Loss.
The transcription factor HBP1 promotes ferroptosis in tumor cells by regulating the UHRF1-CDO1 axis.
Cdo1-Camkk2-AMPK axis confers the protective effects of exercise against NAFLD in mice.
Testosterone enhances taurine synthesis by upregulating androgen receptor and cysteine sulfinic acid decarboxylase expressions in male mouse liver.
Ferroptosis-associated molecular classification characterized by distinct tumor microenvironment profiles in colorectal cancer.
Cdo1 promotes PPARγ-mediated adipose tissue lipolysis in male mice.
Integration of metabolomics and transcriptomics to reveal anti-chronic myocardial ischemia mechanism of Gualou Xiebai decoction.
Cysteine dioxygenase 1 attenuates the proliferation via inducing oxidative stress and integrated stress response in gastric cancer cells.
Integrated application of transcriptome and metabolomics reveals potential therapeutic targets for the polarization of atherosclerotic macrophages.
ADO/hypotaurine: a novel metabolic pathway contributing to glioblastoma development.
Promoter DNA Hypermethylation of the Cysteine Dioxygenase 1 (CDO1) Gene in Intraductal Papillary Mucinous Neoplasm (IPMN).
Cancer-specific promoter DNA methylation of Cysteine dioxygenase type 1 (CDO1) gene as an important prognostic biomarker of gastric cancer.
Clinical significance of cancer specific methylation of the CDO1 gene in small bowel cancer.
Cysteine dioxygenase type 1 (CDO1) gene promoter methylation during the adenoma-carcinoma sequence in colorectal cancer.
Hepatic metabolite profiles in mice with a suboptimal selenium status.
Zhang J, Yimamu M, Cheng Z, Ji J, Wu L, Feng J, Xu X, Wu J, Guo C
Free radical biology & medicine 2024 Jul;219:31-48
Free radical biology & medicine 2024 Jul;219:31-48
Deletion of hepatocyte cysteine dioxygenase type 1, a bile acid repressed gene, enhances glutathione synthesis and ameliorates acetaminophen hepatotoxicity.
Chen J, Matye D, Dai Clayton Y, Du Y, Nazmul Hasan M, Gu L, Li T
Biochemical pharmacology 2024 Apr;222:116103
Biochemical pharmacology 2024 Apr;222:116103
KLF10/CBS increases the sensitivity of gastric carcinoma cells to methionine restriction by promoting sulfur transfer pathway.
Xin L, Liu ZY, Liu CX, Sheng J, Zhou Q, Yuan YW, Yue ZQ, Lu H, Gan JH
Experimental cell research 2024 Apr 1;437(1):114007
Experimental cell research 2024 Apr 1;437(1):114007
Comprehensive Metabolic Tracing Reveals the Origin and Catabolism of Cysteine in Mammalian Tissues and Tumors.
Yoon SJ, Combs JA, Falzone A, Prieto-Farigua N, Caldwell S, Ackerman HD, Flores ER, DeNicola GM
Cancer research 2023 May 2;83(9):1426-1442
Cancer research 2023 May 2;83(9):1426-1442
Taurine Alleviates Chronic Social Defeat Stress-Induced Depression by Protecting Cortical Neurons from Dendritic Spine Loss.
Zhu Y, Wang R, Fan Z, Luo D, Cai G, Li X, Han J, Zhuo L, Zhang L, Zhang H, Li Y, Wu S
Cellular and molecular neurobiology 2023 Mar;43(2):827-840
Cellular and molecular neurobiology 2023 Mar;43(2):827-840
The transcription factor HBP1 promotes ferroptosis in tumor cells by regulating the UHRF1-CDO1 axis.
Yang R, Zhou Y, Zhang T, Wang S, Wang J, Cheng Y, Li H, Jiang W, Yang Z, Zhang X
PLoS biology 2023 Jul;21(7):e3001862
PLoS biology 2023 Jul;21(7):e3001862
Cdo1-Camkk2-AMPK axis confers the protective effects of exercise against NAFLD in mice.
Chen M, Zhu JY, Mu WJ, Luo HY, Li Y, Li S, Yan LJ, Li RY, Guo L
Nature communications 2023 Dec 18;14(1):8391
Nature communications 2023 Dec 18;14(1):8391
Testosterone enhances taurine synthesis by upregulating androgen receptor and cysteine sulfinic acid decarboxylase expressions in male mouse liver.
Zhang D, Fan J, Liu H, Qiu G, Cui S
American journal of physiology. Gastrointestinal and liver physiology 2023 Apr 1;324(4):G295-G304
American journal of physiology. Gastrointestinal and liver physiology 2023 Apr 1;324(4):G295-G304
Ferroptosis-associated molecular classification characterized by distinct tumor microenvironment profiles in colorectal cancer.
Luo W, Dai W, Li Q, Mo S, Han L, Xiao X, Gu R, Xiang W, Ye L, Wang R, Xu Y, Cai S, Cai G
International journal of biological sciences 2022;18(5):1773-1794
International journal of biological sciences 2022;18(5):1773-1794
Cdo1 promotes PPARγ-mediated adipose tissue lipolysis in male mice.
Guo YY, Li BY, Xiao G, Liu Y, Guo L, Tang QQ
Nature metabolism 2022 Oct;4(10):1352-1368
Nature metabolism 2022 Oct;4(10):1352-1368
Integration of metabolomics and transcriptomics to reveal anti-chronic myocardial ischemia mechanism of Gualou Xiebai decoction.
Zhang F, Duan B, Zhou Z, Han L, Huang P, Ye Y, Wang Q, Huang F, Li J
Journal of ethnopharmacology 2022 Oct 28;297:115530
Journal of ethnopharmacology 2022 Oct 28;297:115530
Cysteine dioxygenase 1 attenuates the proliferation via inducing oxidative stress and integrated stress response in gastric cancer cells.
Ma G, Zhao Z, Qu Y, Cai F, Liu S, Liang H, Zhang R, Deng J
Cell death discovery 2022 Dec 16;8(1):493
Cell death discovery 2022 Dec 16;8(1):493
Integrated application of transcriptome and metabolomics reveals potential therapeutic targets for the polarization of atherosclerotic macrophages.
Shen L, Li H, Chen W, Su Y, Yu J, Chen M, Shu G, Qiao E, Guo X, Xu M, Xia S, Zhao Z, Lu C, Ji J
Biochimica et biophysica acta. Molecular basis of disease 2022 Dec 1;1868(12):166550
Biochimica et biophysica acta. Molecular basis of disease 2022 Dec 1;1868(12):166550
ADO/hypotaurine: a novel metabolic pathway contributing to glioblastoma development.
Shen D, Tian L, Yang F, Li J, Li X, Yao Y, Lam EW, Gao P, Jin B, Wang R
Cell death discovery 2021 Jan 22;7(1):21
Cell death discovery 2021 Jan 22;7(1):21
Promoter DNA Hypermethylation of the Cysteine Dioxygenase 1 (CDO1) Gene in Intraductal Papillary Mucinous Neoplasm (IPMN).
Fujiyama Y, Kumamoto Y, Nishizawa N, Nakamoto S, Harada H, Yokota K, Tanaka Y, Igarashi K, Oiki H, Okuwaki K, Iwai T, Kajita S, Takahashi H, Tajima H, Kaizu T, Sasaki J, Watanabe M, Yamashita K
Annals of surgical oncology 2020 Oct;27(10):4007-4016
Annals of surgical oncology 2020 Oct;27(10):4007-4016
Cancer-specific promoter DNA methylation of Cysteine dioxygenase type 1 (CDO1) gene as an important prognostic biomarker of gastric cancer.
Harada H, Hosoda K, Moriya H, Mieno H, Ema A, Ushiku H, Washio M, Nishizawa N, Ishii S, Yokota K, Tanaka Y, Kaida T, Soeno T, Kosaka Y, Watanabe M, Yamashita K
PloS one 2019;14(4):e0214872
PloS one 2019;14(4):e0214872
Clinical significance of cancer specific methylation of the CDO1 gene in small bowel cancer.
Kojima K, Nakamura T, Ooizumi Y, Igarashi K, Tanaka T, Yokoi K, Ishii S, Nishizawa N, Katoh H, Kosaka Y, Sato T, Watanabe M, Yamashita K
PloS one 2019;14(1):e0211108
PloS one 2019;14(1):e0211108
Cysteine dioxygenase type 1 (CDO1) gene promoter methylation during the adenoma-carcinoma sequence in colorectal cancer.
Kojima K, Nakamura T, Ohbu M, Katoh H, Ooizumi Y, Igarashi K, Ishii S, Tanaka T, Yokoi K, Nishizawa N, Yokota K, Kosaka Y, Sato T, Watanabe M, Yamashita K
PloS one 2018;13(5):e0194785
PloS one 2018;13(5):e0194785
Hepatic metabolite profiles in mice with a suboptimal selenium status.
Geillinger KE, Rathmann D, Köhrle J, Fiamoncini J, Daniel H, Kipp AP
The Journal of nutritional biochemistry 2014 Sep;25(9):914-22
The Journal of nutritional biochemistry 2014 Sep;25(9):914-22
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse liver tissue were subjected to SDS PAGE followed by western blot with 12589-1-AP(CDO1 antibody) at dilution of 1:600
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Cysteine dioxygenase type 1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Cysteine dioxygenase type 1. This antibody recognizes human, mouse, rat antigen. The Cysteine dioxygenase type 1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
