Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 12285-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12285-1-AP, RRID:AB_2166239
- Product name
- PLXDC2 antibody
- Antibody type
- Polyclonal
- Description
- PLXDC2 antibody (Cat. #12285-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Prospective isolation of mouse and human hematopoietic stem cells using PLXDC2.
Secreted PTEN binds PLXDC2 on macrophages to drive antitumor immunity and tumor suppression.
Adaptive c-Met-PLXDC2 Signaling Axis Mediates Cancer Stem Cell Plasticity to Confer Radioresistance-associated Aggressiveness in Head and Neck Cancer.
Overexpression of PLXDC2 in Stromal Cell-Associated M2 Macrophages Is Related to EMT and the Progression of Gastric Cancer.
Tanaka Y, Kubota Y, Kikuchi R, Yabushita T, Kimura T, Lieberam I, Barlow JL, Bramley JW, Fukushima T, Sakuma C, Shibata T, Nakagawa M, Kurosawa Y, Maruyama T, Okumura CJ, Arima Y, Sato Y, Ono Y, Akuta T, Mizuno H, Kent DG, Jessell TM, Goyama S, Nishikii H, Kimura S, Yamazaki S, Suda T, Kitamura T
Communications biology 2025 Dec 10;9(1):20
Communications biology 2025 Dec 10;9(1):20
Secreted PTEN binds PLXDC2 on macrophages to drive antitumor immunity and tumor suppression.
Zhang C, Ma HM, Wu S, Shen JM, Zhang N, Xu YL, Li CX, He P, Ge MK, Chu XL, Zhang YX, Zheng JK, Chen GQ, Shen SM
Developmental cell 2024 Dec 2;59(23):3072-3088.e8
Developmental cell 2024 Dec 2;59(23):3072-3088.e8
Adaptive c-Met-PLXDC2 Signaling Axis Mediates Cancer Stem Cell Plasticity to Confer Radioresistance-associated Aggressiveness in Head and Neck Cancer.
Lang L, Chen F, Li Y, Shay C, Yang F, Dan H, Chen ZG, Saba NF, Teng Y
Cancer research communications 2023 Apr;3(4):659-671
Cancer research communications 2023 Apr;3(4):659-671
Overexpression of PLXDC2 in Stromal Cell-Associated M2 Macrophages Is Related to EMT and the Progression of Gastric Cancer.
Guan Y, Du Y, Wang G, Gou H, Xue Y, Xu J, Li E, Chan DW, Wu D, Xu P, Ni P, Xu D, Hu Y
Frontiers in cell and developmental biology 2021;9:673295
Frontiers in cell and developmental biology 2021;9:673295
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The PLXDC2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PLXDC2. This antibody recognizes human, mouse, rat antigen. The PLXDC2 antibody has been validated for the following applications: ELISA, WB analysis.