Antibody data
- Antibody Data
- Antigen structure
- References [13]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 19245-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#19245-1-AP, RRID:AB_10598464
- Product name
- KIF18A antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated KIF18A antibody (Cat. #19245-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references KIF18A inactivates hepatic stellate cells and alleviates liver fibrosis through the TTC3/Akt/mTOR pathway.
Kinesin Family Member-18A (KIF18A) Promotes Cell Proliferation and Metastasis in Hepatocellular Carcinoma.
Comprehensive Pan-Cancer Analysis of KIF18A as a Marker for Prognosis and Immunity.
Prognostic Biomarker KIF18A and Its Correlations With Immune Infiltrates and Mitosis in Glioma.
Kinesin Family Member 18A (KIF18A) Contributes to the Proliferation, Migration, and Invasion of Lung Adenocarcinoma Cells In Vitro and In Vivo.
Overexpression of KIF18A promotes cell proliferation, inhibits apoptosis, and independently predicts unfavorable prognosis in lung adenocarcinoma.
Expression of KIF18A Is Associated with Increased Tumor Stage and Cell Proliferation in Prostate Cancer.
Kif18a regulates Sirt2-mediated tubulin acetylation for spindle organization during mouse oocyte meiosis.
Exclusive destruction of mitotic spindles in human cancer cells.
Eml1 loss impairs apical progenitor spindle length and soma shape in the developing cerebral cortex.
Elevated expression of KIF18A enhances cell proliferation and predicts poor survival in human clear cell renal carcinoma.
High KIF18A expression correlates with unfavorable prognosis in primary hepatocellular carcinoma.
Targeted deletion of Kif18a protects from colitis-associated colorectal (CAC) tumors in mice through impairing Akt phosphorylation.
Zhang H, Xia T, Xia Z, Zhou H, Li Z, Wang W, Zhai X, Jin B
Cellular and molecular life sciences : CMLS 2024 Feb 19;81(1):96
Cellular and molecular life sciences : CMLS 2024 Feb 19;81(1):96
Kinesin Family Member-18A (KIF18A) Promotes Cell Proliferation and Metastasis in Hepatocellular Carcinoma.
Ren J, Yao X, Yang M, Cheng S, Wu D, Xu K, Li R, Zhang H, Zhang D
Digestive diseases and sciences 2024 Apr;69(4):1274-1286
Digestive diseases and sciences 2024 Apr;69(4):1274-1286
Comprehensive Pan-Cancer Analysis of KIF18A as a Marker for Prognosis and Immunity.
Liu T, Yang K, Chen J, Qi L, Zhou X, Wang P
Biomolecules 2023 Feb 8;13(2)
Biomolecules 2023 Feb 8;13(2)
Prognostic Biomarker KIF18A and Its Correlations With Immune Infiltrates and Mitosis in Glioma.
Tao BY, Liu YY, Liu HY, Zhang ZH, Guan YQ, Wang H, Shi Y, Zhang J
Frontiers in genetics 2022;13:852049
Frontiers in genetics 2022;13:852049
Kinesin Family Member 18A (KIF18A) Contributes to the Proliferation, Migration, and Invasion of Lung Adenocarcinoma Cells In Vitro and In Vivo.
Chen FT, Zhong FK
Disease markers 2019;2019:6383685
Disease markers 2019;2019:6383685
Overexpression of KIF18A promotes cell proliferation, inhibits apoptosis, and independently predicts unfavorable prognosis in lung adenocarcinoma.
Zhong Y, Jiang L, Lin H, Li X, Long X, Zhou Y, Li B, Li Z
IUBMB life 2019 Jul;71(7):942-955
IUBMB life 2019 Jul;71(7):942-955
Expression of KIF18A Is Associated with Increased Tumor Stage and Cell Proliferation in Prostate Cancer.
Zhang H, Shen T, Zhang Z, Li Y, Pan Z
Medical science monitor : international medical journal of experimental and clinical research 2019 Aug 27;25:6418-6428
Medical science monitor : international medical journal of experimental and clinical research 2019 Aug 27;25:6418-6428
Kif18a regulates Sirt2-mediated tubulin acetylation for spindle organization during mouse oocyte meiosis.
Tang F, Pan MH, Wan X, Lu Y, Zhang Y, Sun SC
Cell division 2018;13:9
Cell division 2018;13:9
Exclusive destruction of mitotic spindles in human cancer cells.
Visochek L, Castiel A, Mittelman L, Elkin M, Atias D, Golan T, Izraeli S, Peretz T, Cohen-Armon M
Oncotarget 2017 Mar 28;8(13):20813-20824
Oncotarget 2017 Mar 28;8(13):20813-20824
Eml1 loss impairs apical progenitor spindle length and soma shape in the developing cerebral cortex.
Bizzotto S, Uzquiano A, Dingli F, Ershov D, Houllier A, Arras G, Richards M, Loew D, Minc N, Croquelois A, Houdusse A, Francis F
Scientific reports 2017 Dec 11;7(1):17308
Scientific reports 2017 Dec 11;7(1):17308
Elevated expression of KIF18A enhances cell proliferation and predicts poor survival in human clear cell renal carcinoma.
Chen QI, Cao B, Nan N, Wang YU, Zhai XU, Li Y, Chong T
Experimental and therapeutic medicine 2016 Jul;12(1):377-383
Experimental and therapeutic medicine 2016 Jul;12(1):377-383
High KIF18A expression correlates with unfavorable prognosis in primary hepatocellular carcinoma.
Liao W, Huang G, Liao Y, Yang J, Chen Q, Xiao S, Jin J, He S, Wang C
Oncotarget 2014 Nov 15;5(21):10271-9
Oncotarget 2014 Nov 15;5(21):10271-9
Targeted deletion of Kif18a protects from colitis-associated colorectal (CAC) tumors in mice through impairing Akt phosphorylation.
Zhu H, Xu W, Zhang H, Liu J, Xu H, Lu S, Dang S, Kuang Y, Jin X, Wang Z
Biochemical and biophysical research communications 2013 Aug 16;438(1):97-102
Biochemical and biophysical research communications 2013 Aug 16;438(1):97-102
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 19245-1-AP(KIF18A antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 19245-1-AP(KIF18A antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The KIF18A antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human KIF18A. This antibody recognizes human, mouse, rat antigen. The KIF18A antibody has been validated for the following applications: ELISA, WB, IHC analysis.