20702-1-AP

antibody from Proteintech Group

Targeting: IRS2

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

20702-1-AP

Provider

Proteintech Group

Product name

IRS2 antibody

Antibody type

Polyclonal

Description

IRS2 antibody (Cat. #20702-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, WB,ELISA.

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

TangNaikang Formula Alleviates Podocyte Injury in Diabetic Nephropathy by Modulating the SHIP2/PI3K/AKT Pathway.

Yang T, Huang Y, Li W, Qin L, Wu Y, Wu L, Liu T
Journal of diabetes research 2025;2025:6568591

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IL-37 inhibited inflammation to improve gestational diabetes mellitus through the GSK3/NF-κB pathway.

Song M, Zhang G
Diabetology & metabolic syndrome 2025 Jun 5;17(1):193

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A novel covalent inhibitor alleviates type 2 diabetes mellitus by restraining GSK-3β.

Zhang S, Zhao F, Pan C, Wang Y, Yang Z, Yang J, Meng Y, Lv S, Huang J, Dong L, Li L, Dong Y
Biochemical pharmacology 2025 Dec;242(Pt 2):117205

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Artemether regulates liver glycogen and lipid utilization through mitochondrial pyruvate oxidation in db/db mice.

Weng W, Shen L, Yu X, Yuan R, Shao M, Han P, Sun H
American journal of translational research 2024;16(1):27-38

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ASPSCR1::TFE3-mediated upregulation of insulin receptor substrate 2 (IRS-2) activates PI3K/AKT signaling and promotes malignant phenotype.

Ishiguro N, Nakagawa M
The international journal of biochemistry & cell biology 2024 Nov;176:106676

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Microbiota from Exercise Mice Counteracts High-Fat High-Cholesterol Diet-Induced Cognitive Impairment in C57BL/6 Mice.

Li R, Liu R, Chen L, Wang G, Qin L, Yu Z, Wan Z
Oxidative medicine and cellular longevity 2023;2023:2766250

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Role of Protein Tyrosine Phosphatase 1B Inhibitor in Early Brain Injury of Subarachnoid Hemorrhage in Mice.

Zhang ZH, Zhou XM, Zhang X
Brain sciences 2023 May 18;13(5)

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The effect of PINK1/Parkin pathway on glucose homeostasis imbalance induced by tacrolimus in mouse livers.

Li Z, Xiang J, Mei S, Wu Y, Xu Y
Heliyon 2023 Apr;9(4):e15536

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Upregulation of Klotho Aggravates Insulin Resistance in Gestational Diabetes Mellitus Trophoblast Cells.

Lin L, Wang X, Zhao W, Chen Y
Genetics research 2022;2022:1500768

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CircFAT1 Promotes Lung Adenocarcinoma Progression by Sequestering miR-7 from Repressing IRS2-ERK-mediated CCND1 Expression.

Peng H, Zhang W, Dong H, Yuan J, Li Y, Li F, Yu D, Guan Y, Zhang F
International journal of biological sciences 2022;18(10):3944-3960

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Elucidation of the interaction effect between dietary fiber and bound polyphenol components on the anti-hyperglycemic activity of tea residue dietary fiber.

Huang H, Chen J, Hu X, Chen Y, Xie J, Ao T, Wang H, Xie J, Yu Q
Food & function 2022 Mar 7;13(5):2710-2728

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MiR-195 promotes pancreatic β-cell dedifferentiation by targeting Mfn2 and impairing Pi3k/Akt signaling in type 2 diabetes.

Xu Y, Tang Z, Dai H, Hou J, Li F, Tang Z, Zhang D
Obesity (Silver Spring, Md.) 2022 Feb;30(2):447-459

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Postnatal overfeeding induces hepatic microRNA-221 expression and impairs the PI3K/AKT pathway in adult male rats.

Huang F, Zhu P, Wang J, Chen J, Lin W
Pediatric research 2021 Jan;89(1):143-149

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TCF7L2 involvement in estradiol- and progesterone-modulated islet and hepatic glucose homeostasis.

Dong F, Ling Q, Ye D, Zhang Z, Shu J, Chen G, Fei Y, Li C
Scientific reports 2016 Apr 25;6:24859