Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations [0]
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- Product number
- AF3076 - Provider product page
- Provider
- R&D Systems
- Product name
- Human ROBO3 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Detects ROBO3 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 60% cross-reactivity with recombinant mouse ROBO3 is observed, 5% cross-reactivity with recombinant human ROBO2 and recombinant rat ROBO1 is observed, and less than 1% cross-reactivity with recombinant human ROBO4 is observed.
- Reactivity
- Human
- Host
- Goat
- Conjugate
- Unconjugated
- Antigen sequence
Q96MS0
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Ndfip Proteins Target Robo Receptors for Degradation and Allow Commissural Axons to Cross the Midline in the Developing Spinal Cord.
Floor-plate-derived netrin-1 is dispensable for commissural axon guidance.
A-kinase Anchoring Protein 79/150 Recruits Protein Kinase C to Phosphorylate Roundabout Receptors.
The chemorepellent Slit3 promotes monocyte migration.
Gorla M, Santiago C, Chaudhari K, Layman AAK, Oliver PM, Bashaw GJ
Cell reports 2019 Mar 19;26(12):3298-3312.e4
Cell reports 2019 Mar 19;26(12):3298-3312.e4
Floor-plate-derived netrin-1 is dispensable for commissural axon guidance.
Dominici C, Moreno-Bravo JA, Puiggros SR, Rappeneau Q, Rama N, Vieugue P, Bernet A, Mehlen P, Chédotal A
Nature 2017 May 18;545(7654):350-354
Nature 2017 May 18;545(7654):350-354
A-kinase Anchoring Protein 79/150 Recruits Protein Kinase C to Phosphorylate Roundabout Receptors.
Samelson BK, Gore BB, Whiting JL, Nygren PJ, Purkey AM, Colledge M, Langeberg LK, Dell'Acqua ML, Zweifel LS, Scott JD
The Journal of biological chemistry 2015 May 29;290(22):14107-19
The Journal of biological chemistry 2015 May 29;290(22):14107-19
The chemorepellent Slit3 promotes monocyte migration.
Geutskens SB, Hordijk PL, van Hennik PB
Journal of immunology (Baltimore, Md. : 1950) 2010 Dec 15;185(12):7691-8
Journal of immunology (Baltimore, Md. : 1950) 2010 Dec 15;185(12):7691-8
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