Antibody data
- Antibody Data
- Antigen structure
- References [16]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 15790-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15790-1-AP, RRID:AB_10792805
- Product name
- TNFAIP8 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TNFAIP8 antibody (Cat. #15790-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references TIPE proteins control directed migration of human T cells by directing GPCR and lipid second messenger signaling.
TNFAIP8 overexpression aggravates retinal pathophysiological features of diabetic retinopathy.
MicroRNA-483-5p Inhibits Hepatocellular Carcinoma Cell Proliferation, Cell Steatosis, and Fibrosis by Targeting PPARα and TIMP2.
Cyanotoxins Increase Cytotoxicity and Promote Nonalcoholic Fatty Liver Disease Progression by Enhancing Cell Steatosis.
Mechanistic insights into cancer drug resistance through optogenetic PI3K signaling hyperactivation.
TNFAIP8 protein functions as a tumor suppressor in inflammation-associated colorectal tumorigenesis.
Proteomic Analysis of Plasma sEVs Reveals That TNFAIP8 Is a New Biomarker of Cell Proliferation in Diabetic Retinopathy.
MicroRNA-205-5p inhibits skin cancer cell proliferation and increase drug sensitivity by targeting TNFAIP8.
TNFAIP8 drives metabolic reprogramming to promote prostate cancer cell proliferation.
TNFAIP8 regulates autophagy, cell steatosis, and promotes hepatocellular carcinoma cell proliferation.
TNFAIP8 promotes AML chemoresistance by activating ERK signaling pathway through interaction with Rac1.
The TIPE Molecular Pilot That Directs Lymphocyte Migration in Health and Inflammation.
TNFAIP8 promotes prostate cancer cell survival by inducing autophagy.
The Tnfaip8-PE complex is a novel upstream effector in the anti-autophagic action of insulin.
Crucial roles of TNFAIP8 protein in regulating apoptosis and Listeria infection.
Expression and regulation of a novel identified TNFAIP8 family is associated with diabetic nephropathy.
Yu J, Zamani A, Goldsmith JR, Etwebi Z, Lee CN, Chen YH, Sun H
Journal of leukocyte biology 2024 Feb 23;115(3):511-524
Journal of leukocyte biology 2024 Feb 23;115(3):511-524
TNFAIP8 overexpression aggravates retinal pathophysiological features of diabetic retinopathy.
Yang F, Zhang H, Yu X, Tao Q, Zhao C, An J, Zhang X, Li X
Experimental eye research 2023 Sep;234:109572
Experimental eye research 2023 Sep;234:109572
MicroRNA-483-5p Inhibits Hepatocellular Carcinoma Cell Proliferation, Cell Steatosis, and Fibrosis by Targeting PPARα and TIMP2.
Niture S, Gadi S, Qi Q, Gyamfi MA, Varghese RS, Rios-Colon L, Chimeh U, Vandana, Ressom HW, Kumar D
Cancers 2023 Mar 10;15(6)
Cancers 2023 Mar 10;15(6)
Cyanotoxins Increase Cytotoxicity and Promote Nonalcoholic Fatty Liver Disease Progression by Enhancing Cell Steatosis.
Niture S, Gadi S, Qi Q, Rios-Colon L, Khatiwada S, Vandana, Fernando RA, Levine KE, Kumar D
Toxins 2023 Jun 25;15(7)
Toxins 2023 Jun 25;15(7)
Mechanistic insights into cancer drug resistance through optogenetic PI3K signaling hyperactivation.
Ueda Y, Miura Y, Tomishige N, Sugimoto N, Murase M, Kawamura G, Sasaki N, Ishiwata T, Ozawa T
Cell chemical biology 2022 Nov 17;29(11):1576-1587.e5
Cell chemical biology 2022 Nov 17;29(11):1576-1587.e5
TNFAIP8 protein functions as a tumor suppressor in inflammation-associated colorectal tumorigenesis.
Lou Y, Tian X, Sun C, Song M, Han M, Zhao Y, Song Y, Song X, Zhang W, Chen YH, Wang H
Cell death & disease 2022 Apr 6;13(4):311
Cell death & disease 2022 Apr 6;13(4):311
Proteomic Analysis of Plasma sEVs Reveals That TNFAIP8 Is a New Biomarker of Cell Proliferation in Diabetic Retinopathy.
Xiao J, Zhang H, Yang F, Xiao M, Zhou L, Yu R, Shao X, Ea V, Su L, Zhang X, Li X
Journal of proteome research 2021 Mar 5;20(3):1770-1782
Journal of proteome research 2021 Mar 5;20(3):1770-1782
MicroRNA-205-5p inhibits skin cancer cell proliferation and increase drug sensitivity by targeting TNFAIP8.
Ge X, Niture S, Lin M, Cagle P, Li PA, Kumar D
Scientific reports 2021 Mar 11;11(1):5660
Scientific reports 2021 Mar 11;11(1):5660
TNFAIP8 drives metabolic reprogramming to promote prostate cancer cell proliferation.
Niture S, Lin M, Odera JO, Moore J, Zhe H, Chen X, Suy S, Collins SP, Kumar D
The international journal of biochemistry & cell biology 2021 Jan;130:105885
The international journal of biochemistry & cell biology 2021 Jan;130:105885
TNFAIP8 regulates autophagy, cell steatosis, and promotes hepatocellular carcinoma cell proliferation.
Niture S, Gyamfi MA, Lin M, Chimeh U, Dong X, Zheng W, Moore J, Kumar D
Cell death & disease 2020 Mar 9;11(3):178
Cell death & disease 2020 Mar 9;11(3):178
TNFAIP8 promotes AML chemoresistance by activating ERK signaling pathway through interaction with Rac1.
Pang Y, Zhao Y, Wang Y, Wang X, Wang R, Liu N, Li P, Ji M, Ye J, Sun T, Li J, Ma D, Lu F, Ji C
Journal of experimental & clinical cancer research : CR 2020 Aug 14;39(1):158
Journal of experimental & clinical cancer research : CR 2020 Aug 14;39(1):158
The TIPE Molecular Pilot That Directs Lymphocyte Migration in Health and Inflammation.
Sun H, Lin M, Zamani A, Goldsmith JR, Boggs AE, Li M, Lee CN, Chen X, Li X, Li T, Dorrity BL, Li N, Lou Y, Shi S, Wang W, Chen YH
Scientific reports 2020 Apr 20;10(1):6617
Scientific reports 2020 Apr 20;10(1):6617
TNFAIP8 promotes prostate cancer cell survival by inducing autophagy.
Niture S, Ramalinga M, Kedir H, Patacsil D, Niture SS, Li J, Mani H, Suy S, Collins S, Kumar D
Oncotarget 2018 Jun 1;9(42):26884-26899
Oncotarget 2018 Jun 1;9(42):26884-26899
The Tnfaip8-PE complex is a novel upstream effector in the anti-autophagic action of insulin.
Kim JS, Park J, Kim MS, Ha JY, Jang YW, Shin DH, Son JH
Scientific reports 2017 Jul 24;7(1):6248
Scientific reports 2017 Jul 24;7(1):6248
Crucial roles of TNFAIP8 protein in regulating apoptosis and Listeria infection.
Porturas TP, Sun H, Buchlis G, Lou Y, Liang X, Cathopoulis T, Fayngerts S, Johnson DS, Wang Z, Chen YH
Journal of immunology (Baltimore, Md. : 1950) 2015 Jun 15;194(12):5743-50
Journal of immunology (Baltimore, Md. : 1950) 2015 Jun 15;194(12):5743-50
Expression and regulation of a novel identified TNFAIP8 family is associated with diabetic nephropathy.
Zhang S, Zhang Y, Wei X, Zhen J, Wang Z, Li M, Miao W, Ding H, Du P, Zhang W, He M, Yi F
Biochimica et biophysica acta 2010 Nov;1802(11):1078-86
Biochimica et biophysica acta 2010 Nov;1802(11):1078-86
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- A549 cells were subjected to SDS PAGE followed by western blot with 15790-1-AP(TNFAIP8 antibody) at dilution of 1:300
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TNFAIP8 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TNFAIP8. This antibody recognizes human,mouse,rat antigen. The TNFAIP8 antibody has been validated for the following applications: ELISA, WB, IHC analysis.