Antibody data
- Antibody Data
- Antigen structure
- References [17]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 15393-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15393-1-AP, RRID:AB_2091855
- Product name
- DHRS3 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated DHRS3 antibody (Cat. #15393-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The lipid droplet protein DHRS3 is a regulator of melanoma cell state.
Nephron progenitors rhythmically alternate between renewal and differentiation phases that synchronize with kidney branching morphogenesis.
Notch and retinoic acid signals regulate macrophage formation from endocardium downstream of Nkx2-5.
Integrated application of transcriptome and metabolomics reveals potential therapeutic targets for the polarization of atherosclerotic macrophages.
Liver regeneration and ethanol detoxification: A new link in YAP regulation of ALDH1A1 during alcohol-related hepatocyte damage.
Characterization of subunit interactions in the hetero-oligomeric retinoid oxidoreductase complex.
Changes in retinoid metabolism and signaling associated with metabolic remodeling during fasting and in type I diabetes.
Retinol dehydrogenase 11 is essential for the maintenance of retinol homeostasis in liver and testis in mice.
Reprogramming of the retinoic acid pathway in decidualizing human endometrial stromal cells.
Characterization of human short chain dehydrogenase/reductase SDR16C family members related to retinol dehydrogenase 10.
The antagonistically bifunctional retinoid oxidoreductase complex is required for maintenance of all-trans-retinoic acid homeostasis.
The retinaldehyde reductase activity of DHRS3 is reciprocally activated by retinol dehydrogenase 10 to control retinoid homeostasis.
Elevated periimplantation uterine natural killer cell density in human endometrium is associated with impaired corticosteroid signaling in decidualizing stromal cells.
Induction of 11β-HSD 1 and activation of distinct mineralocorticoid receptor- and glucocorticoid receptor-dependent gene networks in decidualizing human endometrial stromal cells.
The retinaldehyde reductase DHRS3 is essential for preventing the formation of excess retinoic acid during embryonic development.
p53-Inducible DHRS3 is an endoplasmic reticulum protein associated with lipid droplet accumulation.
Retinol dehydrogenase 10 but not retinol/sterol dehydrogenase(s) regulates the expression of retinoic acid-responsive genes in human transgenic skin raft culture.
Johns E, Ma Y, Louphrasitthipol P, Peralta C, Hunter MV, Raymond JH, Molina H, Goding CR, White RM
bioRxiv : the preprint server for biology 2024 Mar 28;
bioRxiv : the preprint server for biology 2024 Mar 28;
Nephron progenitors rhythmically alternate between renewal and differentiation phases that synchronize with kidney branching morphogenesis.
Davis SN, Grindel SH, Viola JM, Liu GY, Liu J, Qian G, Porter CM, Hughes AJ
bioRxiv : the preprint server for biology 2024 Jan 13;
bioRxiv : the preprint server for biology 2024 Jan 13;
Notch and retinoic acid signals regulate macrophage formation from endocardium downstream of Nkx2-5.
Liu N, Kawahira N, Nakashima Y, Nakano H, Iwase A, Uchijima Y, Wang M, Wu SM, Minamisawa S, Kurihara H, Nakano A
Nature communications 2023 Sep 5;14(1):5398
Nature communications 2023 Sep 5;14(1):5398
Integrated application of transcriptome and metabolomics reveals potential therapeutic targets for the polarization of atherosclerotic macrophages.
Shen L, Li H, Chen W, Su Y, Yu J, Chen M, Shu G, Qiao E, Guo X, Xu M, Xia S, Zhao Z, Lu C, Ji J
Biochimica et biophysica acta. Molecular basis of disease 2022 Dec 1;1868(12):166550
Biochimica et biophysica acta. Molecular basis of disease 2022 Dec 1;1868(12):166550
Liver regeneration and ethanol detoxification: A new link in YAP regulation of ALDH1A1 during alcohol-related hepatocyte damage.
Zhou J, Sun C, Yang L, Wang J, Jn-Simon N, Zhou C, Bryant A, Cao Q, Li C, Petersen B, Pi L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Apr;36(4):e22224
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Apr;36(4):e22224
Characterization of subunit interactions in the hetero-oligomeric retinoid oxidoreductase complex.
Adams MK, Belyaeva OV, Wu L, Chaple IF, Dunigan-Russell K, Popov KM, Kedishvili NY
The Biochemical journal 2021 Oct 15;478(19):3597-3611
The Biochemical journal 2021 Oct 15;478(19):3597-3611
Changes in retinoid metabolism and signaling associated with metabolic remodeling during fasting and in type I diabetes.
Klyuyeva AV, Belyaeva OV, Goggans KR, Krezel W, Popov KM, Kedishvili NY
The Journal of biological chemistry 2021 Jan-Jun;296:100323
The Journal of biological chemistry 2021 Jan-Jun;296:100323
Retinol dehydrogenase 11 is essential for the maintenance of retinol homeostasis in liver and testis in mice.
Belyaeva OV, Wu L, Shmarakov I, Nelson PS, Kedishvili NY
The Journal of biological chemistry 2018 May 4;293(18):6996-7007
The Journal of biological chemistry 2018 May 4;293(18):6996-7007
Reprogramming of the retinoic acid pathway in decidualizing human endometrial stromal cells.
Ozaki R, Kuroda K, Ikemoto Y, Ochiai A, Matsumoto A, Kumakiri J, Kitade M, Itakura A, Muter J, Brosens JJ, Takeda S
PloS one 2017;12(3):e0173035
PloS one 2017;12(3):e0173035
Characterization of human short chain dehydrogenase/reductase SDR16C family members related to retinol dehydrogenase 10.
Adams MK, Lee SA, Belyaeva OV, Wu L, Kedishvili NY
Chemico-biological interactions 2017 Oct 1;276:88-94
Chemico-biological interactions 2017 Oct 1;276:88-94
The antagonistically bifunctional retinoid oxidoreductase complex is required for maintenance of all-trans-retinoic acid homeostasis.
Belyaeva OV, Adams MK, Wu L, Kedishvili NY
The Journal of biological chemistry 2017 Apr 7;292(14):5884-5897
The Journal of biological chemistry 2017 Apr 7;292(14):5884-5897
The retinaldehyde reductase activity of DHRS3 is reciprocally activated by retinol dehydrogenase 10 to control retinoid homeostasis.
Adams MK, Belyaeva OV, Wu L, Kedishvili NY
The Journal of biological chemistry 2014 May 23;289(21):14868-80
The Journal of biological chemistry 2014 May 23;289(21):14868-80
Elevated periimplantation uterine natural killer cell density in human endometrium is associated with impaired corticosteroid signaling in decidualizing stromal cells.
Kuroda K, Venkatakrishnan R, James S, Šucurovic S, Mulac-Jericevic B, Lucas ES, Takeda S, Shmygol A, Brosens JJ, Quenby S
The Journal of clinical endocrinology and metabolism 2013 Nov;98(11):4429-37
The Journal of clinical endocrinology and metabolism 2013 Nov;98(11):4429-37
Induction of 11β-HSD 1 and activation of distinct mineralocorticoid receptor- and glucocorticoid receptor-dependent gene networks in decidualizing human endometrial stromal cells.
Kuroda K, Venkatakrishnan R, Salker MS, Lucas ES, Shaheen F, Kuroda M, Blanks A, Christian M, Quenby S, Brosens JJ
Molecular endocrinology (Baltimore, Md.) 2013 Feb;27(2):192-202
Molecular endocrinology (Baltimore, Md.) 2013 Feb;27(2):192-202
The retinaldehyde reductase DHRS3 is essential for preventing the formation of excess retinoic acid during embryonic development.
Billings SE, Pierzchalski K, Butler Tjaden NE, Pang XY, Trainor PA, Kane MA, Moise AR
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2013 Dec;27(12):4877-89
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2013 Dec;27(12):4877-89
p53-Inducible DHRS3 is an endoplasmic reticulum protein associated with lipid droplet accumulation.
Deisenroth C, Itahana Y, Tollini L, Jin A, Zhang Y
The Journal of biological chemistry 2011 Aug 12;286(32):28343-56
The Journal of biological chemistry 2011 Aug 12;286(32):28343-56
Retinol dehydrogenase 10 but not retinol/sterol dehydrogenase(s) regulates the expression of retinoic acid-responsive genes in human transgenic skin raft culture.
Lee SA, Belyaeva OV, Wu L, Kedishvili NY
The Journal of biological chemistry 2011 Apr 15;286(15):13550-60
The Journal of biological chemistry 2011 Apr 15;286(15):13550-60
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The DHRS3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human DHRS3. This antibody recognizes human,mouse,rat antigen. The DHRS3 antibody has been validated for the following applications: ELISA, WB analysis.